Cerivastatin, a new inhibitor of HMG-CoA reductase - Pharmacokinetics in rats and dogs

Japanese Pharmacology and Therapeutics

Volumn 24, Issue SUPPL. 9, 1996, Pages 7-27

  Steinke, W ^a   Yamashita, S ^b   Tabei, M ^b   Ahr, H J ^a   Beckermann, B ^a   Domdey Bette, A ^a   Goller G ^a   Schwarz, T ^a   Siefert, H M ^a  

^a BAYER AG   (Germany)

^b BAYER YAKUHIN LTD   (Japan)

Author keywords

Absorption; BAY w 6228; CAS 143201 11 0; Cerivastatin; Distribution; Excretion; HMG CoA reductase inhibitor; Interaction; Mammary excretion; Organ distribution; Pharmacokinetics; Placental transfer; Preclinical; Protein binding; Whole body autoradiography

Indexed keywords

CAS 143201; CERIVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN; PLASMA PROTEIN; SERUM ALBUMIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EXCRETION; ENZYME INHIBITION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERLIPIDEMIA; LIPID METABOLISM; MALE; NONHUMAN; RAT; WHOLE BODY AUTORADIOGRAPHY;

EID: 0029853471     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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