Cyclosporine therapy for acquired factor VIII inhibitor in a patient with systemic lupus erythematosus

Thrombosis and Haemostasis

Volumn 76, Issue 3, 1996, Pages 344-346

  Schulman, S ^a,c   Langevitz, P ^b   Livneh, A ^b   Martinowitz, U ^a   Seligsohn, U ^a   Varon, D ^a  

^a National Hemophilia Center   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c National Hemophilia Center   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 INHIBITOR; CYCLOPHOSPHAMIDE; CYCLOSPORIN; IMMUNOGLOBULIN;

ADULT; ARTICLE; AUTOIMMUNITY; CASE REPORT; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG THERAPY; FEMALE; HEMOPHILIA; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT FAILURE;

EID: 0029853277     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1650581     Document Type: Article

References (16)

1. Green D, Lechner K. A survey of 215 non-hemofilic patients with inhibitors to factor VIII. Thromb Haemost 1981; 45: 200-3.
2. Spero JA, Lewis JH, Hasiba U. Corticosteroid therapy for acquired F VIII:C inhibitors. Br J Haematol 1981; 48: 635-42.
3. Sultan Y, Kazatchkine MD, Maisonneuve P, Nydegger UE. Anti-idiotypic suppression of autoantibodies to factor VIII (antihaemophilic factor) by high-dose intravenous gammaglobulin. Lancet 1984; 2: 765-8.
4. Green D, Rademaker AW, Briët E. A prospective, randomized trial of prednisone and cyclophosphamide in the treatment of patients with F VIII autoantibodies. Thromb Haemost 1993; 70: 753-7.
5. Lian EC-Y, Larcada AF, Chiu AY-Z. Combination immunosuppressive therapy after factor VIII infusion for acquired factor VIII inhibitor. Ann Intern Med 1989; 110: 774-8.
6. Rhodes EGH, Boesen EAM, Corringham RET, Matthews KB, Tuddenham EGD, Kernoff PBA. Disappearance of antibodies to factor VIII in a patient with acquired haemophilia and carcinoma of the pancreas during cytotoxic therapy with fluorouracil and CCNU. Thromb Haemost 1984; 52: 131-3.
7. Schwerdtfeger R, Hintz G, Huhn D. Successful treatment of a patient with postpartum factor VIII inhibitor with recombinant human interferon a 2a. Am J Hematol 1991; 37: 190-3.
8. Hess AD, Colombani PM. Mechanism of action. In: Cyclosporini Progress in Allergy. Borel JF (ed). Karger, Basel 1986; 38: 185-93.
9. Van Buren C. Cyclosporine: progress, problems, and perspectives. Surg Clin North Am 1986; 66: 435-49.
10. Borel JF, von Graffenried B. Sandimmun® (Cyclosporin A) and autoimmunity. In: Recent advances in systemic lupus erythematosus. Lamber PH, Perrin L, Izui S (eds). Academic Press, New York 1983; 313-8.
11. Pijnappels MI, Briët E, van der Zwet G, Huisden R, van Tilburg NH, Euederink F. Evaluation of the cuticle bleeding time in canine haemophilia A. Thromb Haemost 1986; 55: 70-3.
12. Bach JF, Feutren G. Contrasting effects of ciclosporin on humoral and cell-mediated immunity in patients with autoimmune diseases. In: Ciclosporin in autoimmune diseases. Schindler R (ed). Springer-Verlag, Berlin 1985; 33-8.
13. Hart HC, Kraijenhagen RJ, Kerckhaert JAM, Verdel G, Freen M, van de Wiel A. A patient with a spontaneous factor VIII:C autoantibody: Successful treatment with cyclosporine. Transplant Proc 1988; 20 (Suppl 4): 323-8.
14. Pflieger G, Boda Z, Hársfalvi J, FIóra-Nagy M, Sári G, Pecze K, Rak K. Cyclosporin treatment of a woman with acquired haemophilia due to factor VIII:C inhibitor. Postgrad Med J 1989; 65: 400-2.
15. McLeod BC, McKenna R, Chediak J. Treatment of acquired factor VIII inhibitors with antibody removal by apheresis followed by immunosuppression with prednisone and Cyclosporin. Blood 1989; 74 (Suppl): 393 a (abstract).
16. Siegbahn A, Feltelius N, Norlén BJ, Hedner U. Treatment of acquired hemophilia due to F VIII:C autoantibodies with recombinant F VIIa and cyclosporine. Thromb Haemost 1995; 73: 1424 (abstract).