Accumulation and biotransformation of tri-n-butyltin by isolated rainbow trout hepatocytes

Environmental Toxicology and Chemistry

Volumn 15, Issue 11, 1996, Pages 2049-2052

  Reader, Stéphanie ^a   Saint Louis, Richard ^b   Pelletier, Émilien ^b   Denizeau, Francine ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE   (Canada)

Author keywords

Cytochrome P 450; Hepatocytes; Metabolism; Rainbow trout; Tributyltin chloride

Indexed keywords

BUTYLTIN; CYTOCHROME P450;

ARTICLE; BIOTRANSFORMATION; CELL ISOLATION; CELL VIABILITY; DRUG ACCUMULATION; LIVER CELL; NONHUMAN; POLLUTION; PRIORITY JOURNAL; RAINBOW TROUT;

ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 0029852589     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/1551-5028(1996)015<2049:AABOTN>2.3.CO;2     Document Type: Article

References (16)

1. Sijpesteijn, A.K., J.G.A. Luijten and G.J.M Van Der Ker. 1969. Fungicides: An advanced treatise. In D.C. Torgeson, ed., Organometallics and Fungicides. Vol 2. Academic, New York, NY, USA.
2. Walsh, G.E., L.L. McLaughlan, E.M. Lores, M.K. Louie and C.H. Deans. 1985. Effects of organotins on growth and survival of two marine diatoms, Skeletonema costatum and Thalassiosira pseudonama. Chemosphere 14:383-392.
3. Beaumont, A.R. and M.D. Budd. 1984. High mortality of the larvae of the common mussel at low concentrations of tributyllin. Mar. Fallut. Bull. 15:402-406.
4. Alzieu, C.I., J. Sanjuan, J.P. Deltreil and M. Borel. 1986. Tin contamination in Arcachon Bay: Effects on oyster shell anomalies. Mar. Pallut. Bull. 17:494-498.
5. Seinen, W., T. Helder, H. Vernij, A. Penninks and P. Leeuwangh. 1981. Short term toxicity of tri-n-butyltin chloride in rainbow trout (Salmo gairdneri Richardson) yolk sac fry. Sci. Total Environ. 19:155-166.
6. Fent, K. and J.J. Stegeman. 1991. Effects of tributyltin chloride in vitro on the hepatic microsomal monooxygenase system in the fish Stenolomus chrysops. Aquat. Toxicol. 20:159-168.
7. Fent, K. and J.J. Stegeman. 1993. Effects of tributyltin in vivo on hepatic cytochrome P450 forms in marine fish. Aquat. Toxicol. 24:219-240.
8. Reader, S., H.B. Steen and F. Denizeau. 1994. Intracellular calcium and pH alterations induced by tri-n-butyltin chloride in isolated rainbow trout hepatocytes: A flow cytometric analysis. Arch. Biochem. Biophys. 312:407-413.
9. Reader, S., M. Marion and F. Denizeau. 1993. Flow cytometric analysis of the effects of tri-n-butyltin chloride on cytosolic free calcium and thiol levels in isolated rainbow trout hepatocytes. Toxicology 80:117-129.
10. White, I.N.H. 1988. A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin. Anal. Biochem. 172:304-310.
11. Denizeau, F. and M. Marion. 1990. Toxicity of cadmium, copper, and mercury to isolated trout hepatocytes. Can. J. Fish. Aquat. Sci. 47:1038-1042.
12. Saint Louis, R., E. Pelletier, P. Marsot and R. Fournier. 1994. Distribution et effets du chlorure de tributylétain et de ses produits de dégradation sur la croissance de l'algue marine Pavlova lutheri en culture continue. Water Res. 26:2533-2544.
13. Lee, R.F. 1991. Metabolism of tributyltin by marine animals and possible linkages to effects. Mar. Environ. Res. 32:29-35.
14. Lee, R.F. 1986. Metabolism of Bis(tributyltin)oxide by estuarine animals. In Proceedings, Organotin Symposium, Oceans '86, Marine Technology Society, Washington, DC, September 23-25, pp. 1182-1188.
15. Martin, R.C., D.G. Dixon, R.J. Maguire, P.V. Hodson and R.J. Tkacz. 1989. Acute toxicity, uptake, depuration and tissue distribution of tri-n-butyltin in rainbow trout, Salmo gairdneri. Aquat. Toxicol. 15:37-52.
16. Rosenberg, D.W. and G.S. Drummond. 1983. Direct in vitro effects of bis(tri-n-butyltin)oxide on hepatic cytochrome P-450. Biochem. Pharmacol. 32:3823-3829.