메뉴 건너뛰기




Volumn 3, Issue 4, 1996, Pages 349-356

Novel therapeutic strategies via the apoptosis pathways to resolve chronic eosinophilic inflammation

Author keywords

Allergy; Apoptosis; Asthma; Cytokine; Eosinophil; Fas; Inflammation; Interleukin 5; Signal transduction

Indexed keywords

APOPTOSIS; CONTROLLED STUDY; EOSINOPHIL; HUMAN; HUMAN CELL; INFLAMMATION; PHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

EID: 0029852401     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (15)

References (68)
  • 1
    • 0028226536 scopus 로고
    • Leucocyte-endothelial interactions and regulation of leucocyte migration
    • Adams DH and Shaw S (1994) Leucocyte-endothelial interactions and regulation of leucocyte migration. Lancet 343: 831-835
    • (1994) Lancet , vol.343 , pp. 831-835
    • Adams, D.H.1    Shaw, S.2
  • 2
    • 8044237256 scopus 로고
    • Transmembrane signaling by the high-affinity receptor for Igε on mast cells - Prospects for intervention
    • Atkinson TP and Hohman RJ (1995) Transmembrane signaling by the high-affinity receptor for Igε on mast cells - prospects for intervention. ACI News 7: 10-14
    • (1995) ACI News , vol.7 , pp. 10-14
    • Atkinson, T.P.1    Hohman, R.J.2
  • 3
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A and Karin M (1995) Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis. Science 270: 286-290
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 5
    • 43949153331 scopus 로고
    • CC chemokines in allergic inflammation
    • Baggiolini M and Dahinden CA (1994) CC chemokines in allergic inflammation. Immunol. Today 15: 127-133
    • (1994) Immunol. Today , vol.15 , pp. 127-133
    • Baggiolini, M.1    Dahinden, C.A.2
  • 6
    • 14744292253 scopus 로고
    • Apoptosis and its role in human disease
    • Barr PJ and Tomei LD (1994) Apoptosis and its role in human disease. Bio/Technol. 12: 487-493
    • (1994) Bio/Technol. , vol.12 , pp. 487-493
    • Barr, P.J.1    Tomei, L.D.2
  • 8
    • 0027255942 scopus 로고
    • Apoptosis and diseases
    • Carson DA and Ribeiro JM (1993) Apoptosis and diseases. Lancet 341: 1251-1254
    • (1993) Lancet , vol.341 , pp. 1251-1254
    • Carson, D.A.1    Ribeiro, J.M.2
  • 9
    • 0029066697 scopus 로고
    • Contenders in FasL/TNF death signaling
    • Cleveland JL and Ihle JN (1995) Contenders in FasL/TNF death signaling. Cell 81: 479-482
    • (1995) Cell , vol.81 , pp. 479-482
    • Cleveland, J.L.1    Ihle, J.N.2
  • 10
    • 0023895299 scopus 로고
    • T lymphocyte activation in acute severe asthma
    • Corrigan CJ, Hartnell A and Kay AB (1988) T lymphocyte activation in acute severe asthma. Lancet: 1: 1129-1131
    • (1988) Lancet , vol.1 , pp. 1129-1131
    • Corrigan, C.J.1    Hartnell, A.2    Kay, A.B.3
  • 11
    • 0029299370 scopus 로고
    • Peripheral blood CD4 but not CD8 T-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: Effect of glucocorticoid therapy
    • Corrigan CJ, Hamid Q, North J, Barkans J, Moqbel R, Durham S, Gemou-Engesaeth V and Kay AB (1995) Peripheral blood CD4 but not CD8 T-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: Effect of glucocorticoid therapy. Am. J. Respir. Cell Mol. Biol. 12: 567-578
    • (1995) Am. J. Respir. Cell Mol. Biol. , vol.12 , pp. 567-578
    • Corrigan, C.J.1    Hamid, Q.2    North, J.3    Barkans, J.4    Moqbel, R.5    Durham, S.6    Gemou-Engesaeth, V.7    Kay, A.B.8
  • 12
    • 0026482756 scopus 로고
    • Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens
    • Dhein J, Daniel PT, Trauth BC, Oehm A, Möller P and Krammer PH (1992) Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. J. Immunol. 149: 3166-3173
    • (1992) J. Immunol. , vol.149 , pp. 3166-3173
    • Dhein, J.1    Daniel, P.T.2    Trauth, B.C.3    Oehm, A.4    Möller, P.5    Krammer, P.H.6
  • 14
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y and Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119: 493-501
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 15
    • 0028015581 scopus 로고
    • Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis
    • Hamid Q, Boguniewicz M and Leung DYM (1994) Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis. J. Clin. Invest. 94: 870-876
    • (1994) J. Clin. Invest. , vol.94 , pp. 870-876
    • Hamid, Q.1    Boguniewicz, M.2    Leung, D.Y.M.3
  • 16
    • 0028670378 scopus 로고
    • Analysis of the role of bcl-2 in apoptosis
    • Hawkins CJ and Vaux DL (1994) Analysis of the role of bcl-2 in apoptosis. Immunol. Rev. 142: 127-139
    • (1994) Immunol. Rev. , vol.142 , pp. 127-139
    • Hawkins, C.J.1    Vaux, D.L.2
  • 17
    • 0025637605 scopus 로고
    • Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): Reconstitution of a high-affinity GM-CSF receptor
    • Hayashida K, Kitamura T, Gorman DM, Arai KI, Yokota T and Miyajima A (1990) Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): Reconstitution of a high-affinity GM-CSF receptor. Proc. Natl. Acad. Sci. USA 87: 9655-9659
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9655-9659
    • Hayashida, K.1    Kitamura, T.2    Gorman, D.M.3    Arai, K.I.4    Yokota, T.5    Miyajima, A.6
  • 19
    • 0026315499 scopus 로고
    • Eosinophil hematopoietins antagonize the programmed cell death of eosinophils. Cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium
    • Her E, Frazer J, Austen F and Owen WF (1991) Eosinophil hematopoietins antagonize the programmed cell death of eosinophils. Cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium. J. Clin. Invest. 88: 1982-1987
    • (1991) J. Clin. Invest. , vol.88 , pp. 1982-1987
    • Her, E.1    Frazer, J.2    Austen, F.3    Owen, W.F.4
  • 22
    • 0025861759 scopus 로고
    • Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors
    • Kitamura T, Sato N, Arai K and Miyajima A (1991) Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors. Cell 66: 1165-1174
    • (1991) Cell , vol.66 , pp. 1165-1174
    • Kitamura, T.1    Sato, N.2    Arai, K.3    Miyajima, A.4
  • 23
    • 0026695699 scopus 로고
    • Bcl-2: A repressor of lymphocyte death
    • Korsmeyer SJ (1992) Bcl-2: a repressor of lymphocyte death, Immunol. Today 13: 285-288
    • (1992) Immunol. Today , vol.13 , pp. 285-288
    • Korsmeyer, S.J.1
  • 25
    • 0026454547 scopus 로고
    • GM-CSF, IL-3 and IL-5: Cross-competition on human haemopoietic cells
    • Lopez AF, Elliott MJ, Woodcock J and Vadas MA (1992) GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells, Immunol. Today 13: 495-500
    • (1992) Immunol. Today , vol.13 , pp. 495-500
    • Lopez, A.F.1    Elliott, M.J.2    Woodcock, J.3    Vadas, M.A.4
  • 27
    • 0029148643 scopus 로고
    • Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro
    • Matsumoto K, Schleimer RP, Saito H, Iikura Y and Bochner BS (1995) Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro. Blood 86: 1437-1443
    • (1995) Blood , vol.86 , pp. 1437-1443
    • Matsumoto, K.1    Schleimer, R.P.2    Saito, H.3    Iikura, Y.4    Bochner, B.S.5
  • 28
    • 0029863130 scopus 로고    scopus 로고
    • P-glycoprotein expression in circulating blood leucocytes of patients with steroid-resistant asthma
    • Montano E, Schmitz M, Blaser K and Simon HU (1996) P-glycoprotein expression in circulating blood leucocytes of patients with steroid-resistant asthma. J. Invest. Allergol. Clin, Immunol. 6: 14-21
    • (1996) J. Invest. Allergol. Clin, Immunol. , vol.6 , pp. 14-21
    • Montano, E.1    Schmitz, M.2    Blaser, K.3    Simon, H.U.4
  • 29
    • 0026692094 scopus 로고
    • IL-4 controls selective endothelium-driven transmigration of eosinophils from allergic individuals
    • Moser R, Fehr J and Bruijnzeel PLB (1992) IL-4 controls selective endothelium-driven transmigration of eosinophils from allergic individuals. J. Immunol. 149: 1432-1438
    • (1992) J. Immunol. , vol.149 , pp. 1432-1438
    • Moser, R.1    Fehr, J.2    Bruijnzeel, P.L.B.3
  • 30
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S and Golstein P (1995) The Fas death factor. Science 267: 1449-1456
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 31
    • 0026706261 scopus 로고
    • Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/ nerve growth factor receptor superfamily: Sequence identity with the Fas antigen
    • Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, Ponstingl H and Krammer PH (1992) Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/ nerve growth factor receptor superfamily: sequence identity with the Fas antigen. J. Biol. Chem. 267: 10709-10715
    • (1992) J. Biol. Chem. , vol.267 , pp. 10709-10715
    • Oehm, A.1    Behrmann, I.2    Falk, W.3    Pawlita, M.4    Maier, G.5    Klas, C.6    Li-Weber, M.7    Richards, S.8    Dhein, J.9    Trauth, B.C.10    Ponstingl, H.11    Krammer, P.H.12
  • 33
    • 0029058148 scopus 로고
    • The activation of the Jak-STAT 1 signaling pathway by IL-5 in eosinophils
    • Pazdrak K, Stafford S and Alam R (1995a) The activation of the Jak-STAT 1 signaling pathway by IL-5 in eosinophils. J. Immunol. 155: 397-402
    • (1995) J. Immunol. , vol.155 , pp. 397-402
    • Pazdrak, K.1    Stafford, S.2    Alam, R.3
  • 34
    • 0028881246 scopus 로고
    • Mechanism of inhibition of eosinophil activation by transforming growth factor-β. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor
    • Pazdrak K, Justement L and Alam R (1995b) Mechanism of inhibition of eosinophil activation by transforming growth factor-β. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor. J. Immunol. 155: 4454-4458.
    • (1995) J. Immunol. , vol.155 , pp. 4454-4458
    • Pazdrak, K.1    Justement, L.2    Alam, R.3
  • 35
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff, MC (1992) Social controls on cell survival and cell death. Nature 356: 397-400
    • (1992) Nature , vol.356 , pp. 397-400
    • Raff, M.C.1
  • 37
    • 0027183057 scopus 로고
    • Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-γ cytokine gene expression
    • Robinson D, Hamid Q, Ying S, Bentley A, Assoufi B, Durham S and Kay AB (1993) Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-γ cytokine gene expression. Am. Rev. Respir. Dis. 148: 401-406
    • (1993) Am. Rev. Respir. Dis. , vol.148 , pp. 401-406
    • Robinson, D.1    Hamid, Q.2    Ying, S.3    Bentley, A.4    Assoufi, B.5    Durham, S.6    Kay, A.B.7
  • 38
    • 0030036618 scopus 로고    scopus 로고
    • Platelet-activating factor exerts mitogenic activity and stimulates expression of interleukin-6 and interleukin-8 in human lung fibroblasts via binding to its functional receptor
    • Roth M, Nauck M, Yousefi S, Tamm M, Blaser K, Perruchoud AP and Simon HU (1996) Platelet-activating factor exerts mitogenic activity and stimulates expression of interleukin-6 and interleukin-8 in human lung fibroblasts via binding to its functional receptor. J. Exp. Med. 184: 191-201
    • (1996) J. Exp. Med. , vol.184 , pp. 191-201
    • Roth, M.1    Nauck, M.2    Yousefi, S.3    Tamm, M.4    Blaser, K.5    Perruchoud, A.P.6    Simon, H.U.7
  • 39
    • 0023882364 scopus 로고
    • Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3
    • Rothenberg ME, Owen WF, Silberstein DS, Wood SJ, Soberman RJ, Austen KF and Stevens RL (1988) Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J. Clin. Invest. 81: 1986-1992
    • (1988) J. Clin. Invest. , vol.81 , pp. 1986-1992
    • Rothenberg, M.E.1    Owen, W.F.2    Silberstein, D.S.3    Wood, S.J.4    Soberman, R.J.5    Austen, K.F.6    Stevens, R.L.7
  • 40
    • 0028335948 scopus 로고
    • Anchorage dependence, integrins, and apoptosis
    • Ruoslahti E and Reed JC (1994) Anchorage dependence, integrins, and apoptosis. Cell 77: 477-478
    • (1994) Cell , vol.77 , pp. 477-478
    • Ruoslahti, E.1    Reed, J.C.2
  • 41
    • 0029005587 scopus 로고
    • Activation-induced death of mature T-cells in the regulation of immune responses
    • Russell JH (1995) Activation-induced death of mature T-cells in the regulation of immune responses. Curr. Opin. Immunol. 7: 382-388
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 382-388
    • Russell, J.H.1
  • 42
    • 0027494821 scopus 로고
    • Signal transduction by the high-affinity GM-CSF receptor: Two distinct cytoplasmic regions of the common β subunit
    • Sato N, Sakamaki K, Tereda N, Arai K and Miyajima A (1993) Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common β subunit. EMBO J. 12: 4181-4189
    • (1993) EMBO J. , vol.12 , pp. 4181-4189
    • Sato, N.1    Sakamaki, K.2    Tereda, N.3    Arai, K.4    Miyajima, A.5
  • 44
    • 0029066512 scopus 로고
    • FAP-1: A protein tyrosine phosphatase that associates with Fas
    • Sato T, Irie S, Kitada S and Reed JC (1995) FAP-1: a protein tyrosine phosphatase that associates with Fas. Science 268: 411-415
    • (1995) Science , vol.268 , pp. 411-415
    • Sato, T.1    Irie, S.2    Kitada, S.3    Reed, J.C.4
  • 45
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK and Baldwin Jr, AS (1995) Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 270: 283-286
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 47
    • 0027762770 scopus 로고
    • Interleukin-8 is a chemoattractant for eosinophils purified from subjects with a blood eosinophilia but not from healthy subjects
    • Sehmi R, Cromwell O, Wardlaw AJ, Moqbel R and Kay AB (1994) Interleukin-8 is a chemoattractant for eosinophils purified from subjects with a blood eosinophilia but not from healthy subjects. Clin. Exp. Allergy 23: 1027-1036
    • (1994) Clin. Exp. Allergy , vol.23 , pp. 1027-1036
    • Sehmi, R.1    Cromwell, O.2    Wardlaw, A.J.3    Moqbel, R.4    Kay, A.B.5
  • 48
    • 0028878377 scopus 로고
    • Inhibition of programmed eosinophil death: A key pathogenic event for eosinophilia?
    • Simon HU and Blaser K (1995) Inhibition of programmed eosinophil death: a key pathogenic event for eosinophilia? Immunol. Today 16: 53-55
    • (1995) Immunol. Today , vol.16 , pp. 53-55
    • Simon, H.U.1    Blaser, K.2
  • 49
    • 0028428101 scopus 로고
    • High altitude climate therapy reduces peripheral blood T lymphocyte activation, eosinophilia, and bronchial obstruction in children with house-dust mite allergic asthma
    • Simon HU, Grotzer M, Nikolaizik WH, Blaser K and Schöni MH (1994a) High altitude climate therapy reduces peripheral blood T lymphocyte activation, eosinophilia, and bronchial obstruction in children with house-dust mite allergic asthma. Pediatr. Pulmonol. 17: 304-311
    • (1994) Pediatr. Pulmonol. , vol.17 , pp. 304-311
    • Simon, H.U.1    Grotzer, M.2    Nikolaizik, W.H.3    Blaser, K.4    Schöni, M.H.5
  • 50
    • 0028308265 scopus 로고
    • Functional platelet-activating factor receptors are expressed by monocytes and granulocytes but not by resting or activated T and B lymphocytes from normal individuals or patients with asthma
    • Simon HU, Tsao PW, Siminovitch KA, Mills GB and Blaser K (1994b) Functional platelet-activating factor receptors are expressed by monocytes and granulocytes but not by resting or activated T and B lymphocytes from normal individuals or patients with asthma. J. Immunol. 153: 364-377
    • (1994) J. Immunol. , vol.153 , pp. 364-377
    • Simon, H.U.1    Tsao, P.W.2    Siminovitch, K.A.3    Mills, G.B.4    Blaser, K.5
  • 52
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer TA (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301-314
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 53
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H (1995) Mechanisms and genes of cellular suicide. Science 267: 1445-1449
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 54
    • 0026580593 scopus 로고
    • Apoptosis in human eosinophils. Programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5
    • Stern M, Meagher L, Savill J and Haslett C (1992) Apoptosis in human eosinophils. Programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5. J. Immunol. 148: 3543-3549
    • (1992) J. Immunol. , vol.148 , pp. 3543-3549
    • Stern, M.1    Meagher, L.2    Savill, J.3    Haslett, C.4
  • 55
    • 0025769977 scopus 로고
    • Effects of IL-5, granulocyte/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro
    • Tai PC, Sun L and Spry CJF (1991) Effects of IL-5, granulocyte/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro. Clin. Exp. Immunol. 85: 312-316
    • (1991) Clin. Exp. Immunol. , vol.85 , pp. 312-316
    • Tai, P.C.1    Sun, L.2    Spry, C.J.F.3
  • 56
    • 0025770219 scopus 로고
    • A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF
    • Tavernier J, Devos R, Cornelis S, Tuypens T, van der Heyden J, Fiers W and Plaetinck G (1991) A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF. Cell 66: 1175-1184
    • (1991) Cell , vol.66 , pp. 1175-1184
    • Tavernier, J.1    Devos, R.2    Cornelis, S.3    Tuypens, T.4    Van Der Heyden, J.5    Fiers, W.6    Plaetinck, G.7
  • 58
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB (1995) Apoptosis in the pathogenesis and treatment of disease. Nature 267: 1456-1462
    • (1995) Nature , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 60
    • 0028864183 scopus 로고
    • Activation of the Fas receptor on lung eosinophils leads to apoptosis and resolution of eosinophilic inflammation of the airways
    • Tsuyuki S, Bertrand C, Erard F, Trifilieff A, Tsuyuki J, Wesp M, Anderson GP and Coyle AJ (1995) Activation of the Fas receptor on lung eosinophils leads to apoptosis and resolution of eosinophilic inflammation of the airways. J. Clin. Invest. 96: 2924-2931
    • (1995) J. Clin. Invest. , vol.96 , pp. 2924-2931
    • Tsuyuki, S.1    Bertrand, C.2    Erard, F.3    Trifilieff, A.4    Tsuyuki, J.5    Wesp, M.6    Anderson, G.P.7    Coyle, A.J.8
  • 62
    • 0026666718 scopus 로고
    • Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
    • Walker C, Bode E, Boer L, Hansel TT, Blaser K and Virchow JC (1992) Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am. Rev. Respir. Dis. 146: 109-115
    • (1992) Am. Rev. Respir. Dis. , vol.146 , pp. 109-115
    • Walker, C.1    Bode, E.2    Boer, L.3    Hansel, T.T.4    Blaser, K.5    Virchow, J.C.6
  • 63
    • 0025805857 scopus 로고
    • T-cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma
    • Walker C, Virchow JC, Bruijnzeel PLB and Blaser K (1991) T-cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J. Immunol. 146: 1829-1835
    • (1991) J. Immunol. , vol.146 , pp. 1829-1835
    • Walker, C.1    Virchow, J.C.2    Bruijnzeel, P.L.B.3    Blaser, K.4
  • 64
    • 0025841768 scopus 로고
    • Glucocorticoids inhibit cytokine-mediated eosinophil survival
    • Wallen N, Kita H, Weiler D and Gleich GJ (1991) Glucocorticoids inhibit cytokine-mediated eosinophil survival. J. Immunol. 147: 3490-3495
    • (1991) J. Immunol. , vol.147 , pp. 3490-3495
    • Wallen, N.1    Kita, H.2    Weiler, D.3    Gleich, G.J.4
  • 65
    • 0025723962 scopus 로고
    • Analysis of the survival of mature human eosinophils: Interleukin-5 prevents apoptosis in mature human eosinophils
    • Yamaguchi Y, Suda T, Ohta S, Tominaga K, Miura Y and Kasahara T (1991) Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature human eosinophils. Blood 78: 2542-2547
    • (1991) Blood , vol.78 , pp. 2542-2547
    • Yamaguchi, Y.1    Suda, T.2    Ohta, S.3    Tominaga, K.4    Miura, Y.5    Kasahara, T.6
  • 66
    • 0028000264 scopus 로고
    • Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils
    • Yousefi S, Green DR, Blaser K and Simon HU (1994) Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc. Natl. Acad. Sci. USA 91: 10868-10872
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10868-10872
    • Yousefi, S.1    Green, D.R.2    Blaser, K.3    Simon, H.U.4
  • 67
    • 0029017519 scopus 로고
    • IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma
    • Yousefi S, Hemmann S, Weber M, Hölzer C, Hartung K, Blaser K and Simon HU (1995) IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma. J. Immunol. 154: 5481-5490
    • (1995) J. Immunol. , vol.154 , pp. 5481-5490
    • Yousefi, S.1    Hemmann, S.2    Weber, M.3    Hölzer, C.4    Hartung, K.5    Blaser, K.6    Simon, H.U.7
  • 68
    • 0029913802 scopus 로고    scopus 로고
    • Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils
    • Yousefi S, Hoessli DC, Blaser K, Mills GB and Simon HU (1996) Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils. J. Exp. Med. 183: 1407-1414
    • (1996) J. Exp. Med. , vol.183 , pp. 1407-1414
    • Yousefi, S.1    Hoessli, D.C.2    Blaser, K.3    Mills, G.B.4    Simon, H.U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.