Tumor suppressor p53 gene forms multiple isoforms: Evidence for single locus origin and cytoplasmic complex formation with heat shock proteins

Electrophoresis

Volumn 17, Issue 11, 1996, Pages 1764-1771

  Selkirk, James K ^a,b   He, Chaoying ^a   Patterson, Rachel M ^a   Merrick, B Alex ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b Lab of Molecular Carcinogenesis   (United States)

Author keywords

Cell culture; Heat shock proteins; Tumor suppressor p53 gene; Two dimensional polyacrylamide gel electrophoresis

Indexed keywords

ELECTROPHORESIS; GENES; PROTEINS; TUMORS;

CELL-CYCLE CONTROLS; COMPLEX FORMATIONS; CONTROL FACTORS; HEAT SHOCK PROTEIN; ISOFORMS; P53 GENE; TUMOR SUPPRESSOR P53 GENE; TUMOR SUPPRESSOR PROTEINS; TUMOUR SUPPRESSOR; TWO-DIMENSIONAL POLYACRYLAMIDE GEL ELECTROPHORESIS;

CELL CULTURE;

HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; PROTEIN P53;

ARTICLE; GENE EXPRESSION; HUMAN; IMMUNOPRECIPITATION; MALIGNANT TRANSFORMATION; MUTATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; TUMOR SUPPRESSOR GENE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 0029851968     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.1150171114     Document Type: Article

References (48)

1. DeLeo, A. B., Jay, G., Appella, E., Dubois, G. C., Law, W. L., Old, L. J., Proc. Natl. Acad. Sci. USA 1979, 76, 2420-2424.
2. Lane, D. P., Crawford, L. V., Nature 1979, 278, 261-263.
3. Linzer, D. I. H., Levine, A. J., Cell 1979, 17, 43-52.
4. Lane, D. P., Crawford, L. V., Nature 1979, 278, 261-263.
5. Eliyahu, D., Raz, A., Gruss, P., Givol, D., Oren, M., Nature 1984, 312, 646-649.
6. Parada, L. F., Land, H., Weinberg, R. A., Wolf, D., Rotter, V., Nature 1984, 312, 649-651.
7. Hinds, P. W., Finlay, C., Levine, A. J., Villarreal, L. P. (Ed.), Common Mechanisms of Transformation by Small DNA Tumor Viruses, American Society for Microbiology, Washington, DC 1989, pp. 33-101.
8. Finlay, C. A., Hinds, P. W., Levine, A. J., Cell 1989, 57, 1083-1093.
9. Baker, S. J., Markowitz, S., Fearon, E. R., Wilson, J. K. U., Vogelstein, B., Science 1990, 249, 912-915.
10. Chen, P.-L., Chen, Y., Bookstein, R., Lee, W.-H., Science 1990, 250, 1576-1580.
11. Diller, L., Kassel, J., Nelson, C. E., Gryka, M. A., Litwak, G., Gebhardt, M., Bressac, B., Ozturk, M., Baker, S. J., Vogelstein, B., Mol. Cell. Biol. 1990, 10, 5772-5781.
12. Mercer, W. E., Amin, M., Sauve, G. J., Appella, E., Ullrich, S. J., Romano, J., Oncogene 1990, 5, 973-980.
13. Mercer, W. E., Shields, M. T., Amin, M., Sauve, G. J., Appella, E., Ullrich, S. J., Proc. Natl. Acad. Sci. USA 1990, 87, 6166-6170.
14. Oren, M., Maltzman, W., Levine, A. J., Mol. Cell Biol. 1981, 1, 101-110.
15. Reich, N., Oren, M., Levine, A. J., Mol. Cell. Biol. 1983, 3, 2143-2150.
16. Hinds, P. W., Finlay, C. A., Quartin, R. S., Baker, S. J., Fearon, E. R., Vogelstein, B., Levine, A. J., Cell Growth Differ. 1990, 1, 571-580.
17. Milner, J., Medcalf, E. A., Cell 1991, 65, 765-774.
18. Pinhasi-Kimhi, O., Michalovitz, D., Ben-Zeev, A., Oren, M., Nature 1986, 320, 182-185.
19. Sturtzbecher, H.-W., Chumakov, P., Welch, W. J., Jenkins, J. R., Oncogene 1987, 1, 201-211.
20. Hinds, P. W., Finlay, C., Frey, A., Levine, A. J., Mol. Cell. Biol. 1987, 7, 2862-2869.
21. Finlay, C. A., Hinds, P. W., Tan, T.-H., Eliyahu, D., Oren, M., Levine, A. J., Mol. Cell. Biol. 1988, 8, 531-539.
22. Clarke, C. F., Cheng, K., Frey, A. B., Stein, R., Hinds, P. W., Levine, A. J., Mol. Cell. Biol. 1988, 8, 1206-1215.
23. Yewdell, J., Gannon, J. V., Lane, D. P., J. Virol. 1986, 59, 444-452.
24. Tan, T.-H., Wallis, J., Levine, A. J., J Virol. 1986, 59, 574-583.
25. Clarke, C. F., Cheng, K., Frey, A. B., Stein, R., Hinds, P. W., Levine, A. J., Mol. Cell. Biol. 1988, 8, 1206-1215.
26. Baker, S. J., Markowitz, S., Fearon, E. R., Wilson, J. K. U., Vogelstein, B., Science 1990, 249, 912-915.
27. Pelham, H. R. B., Cell 1986, 46, 959-961.
28. Davidoff, A. M., Iglehart, J. D., Marks, J. D., Proc. Natl. Acad. Sci. USA 1992, 89, 3439-3442.
29. Rothman, J. E., Cell 1989, 59, 591-601.
30. Levine, A. J., Virology 1990, 177, 419-426.
31. Momand, J., Zambetti, G. P., Olsen, D. C., George, D., Levine, A. J., Cell 1992, 69, 1237-1245.
32. Fakharzadeh, S. S., Trusko, S. P., George, D., EMBO J. 1991, 10, 1565-1569.
33. Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M., Hostetter, R., Cleary, K., Bigner, S. H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Collins, F. S., Weston, A., Modali, R., Harris, C. C., Vogelstein, B., Nature 1989, 342, 705-708.
34. Selkirk, J. K., He, C., Merrick, M. B., Appl. Theoret. Electrophoresis 1994, 4, 11-18.
35. Ullrich, S. J., Mercer, W. E., Appella, E., Oncogene 1992, 7, 1635-1643.
36. Merrick, B. A., Pence, M. P., He, C., Patterson, R. M., Selkirk, J. K., BioTechniques 1995, 18, 292-299.
37. Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A. J., Butel, J. S., Bradley, A., Nature 1992, 356, 215-221.
38. Selkirk, J. K., He, C., Merrick, B. M., Appl. Theoret. Electrophoresis 1994, 4, 89-93.
39. Merrick, B. A., He, C., Witcher, L. L., Patterson, R. M., Reid, J. J., Pence-Pawloski, P. M., Selkirk, J. K., Biochim Biophys. Acta 1996, in press.
40. Anderson, M. J., Casey, G., Fasching, C. L., Stanbridge, E. J., Genes Choromosom. Cancer 1994, 9, 266-281.
41. Cannon, J. V., Greaves, R., Iggo, R., Lane, D. P., EMBO J., 1990, 9, 1595-1602.
42. Mizzen, L. A., Chang, C., Garrels, J. I., Welch, W. J., J. Biol. Chem. 1989, 264, 2064-2067.
43. Perdew, G., Whitelaw, M., J. Biol. Chem. 1991, 266, 6708-6713.
44. Baker, S. J., Vogelstein, B., in: Sharp, P. A. (Ed.), Nuclear Processes and Oncogenes, Academic Press, San Diego 1992, pp. 87-104.
45. Sanchez, E. R., Hirst, M., Scherrer, L. C., Tang, H., Welsh, M. J., Harmon, J. M., Simons, S. S., Jr., Ringold, G. M., Pratt, W. B., J. Biol. Chem. 1990, 265, 20123-20130.
46. Whitelaw, M. L., Hutchison, K., Perdew, G. H., J. Biol. Chem. 1991, 266, 16436-16440.
47. Gruppi, C. M., Wolgemuth, D. J., Devel. Gen. 1993, 14, 119-126.
48. Gething, M. J., Sambrook, J., Nature 1992, 355, 33-45.