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Volumn 64, Issue 12, 1996, Pages 5129-5137

Surface Zn-proteinase as a molecule for defense of Leishmania mexicana amazonensis promastigotes against cytolysis inside macrophage phagolysosomes

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE; CHLORAMPHENICOL ACETYLTRANSFERASE; PARASITE ANTIGEN; PROTEINASE; ZINC;

EID: 0029851699     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.12.5129-5137.1996     Document Type: Article
Times cited : (61)

References (62)
  • 1
    • 0029098551 scopus 로고
    • Recombinant BCG expressing the Leishmania surface antigen gp63 induces protective immunity against Leishimania major infection in BALB/c mice
    • Abdelhak, S., H. Louzir, J. Timm, L. Blel, Z. Benlasfar, M. Lagranderie, M. Gheorghlu, K. Dellagi, and B. Gicquel. 1995. Recombinant BCG expressing the Leishmania surface antigen gp63 induces protective immunity against Leishimania major infection in BALB/c mice. Microbiology 141:1585-1592.
    • (1995) Microbiology , vol.141 , pp. 1585-1592
    • Abdelhak, S.1    Louzir, H.2    Timm, J.3    Blel, L.4    Benlasfar, Z.5    Lagranderie, M.6    Gheorghlu, M.7    Dellagi, K.8    Gicquel, B.9
  • 2
    • 0026533657 scopus 로고
    • The interaction of Leishmania species with macrophages
    • Alexander, J., and D. G. Russell. 1992. The interaction of Leishmania species with macrophages. Adv. Parasitol. 31:175-254.
    • (1992) Adv. Parasitol. , vol.31 , pp. 175-254
    • Alexander, J.1    Russell, D.G.2
  • 4
    • 0025064922 scopus 로고
    • Receptor mediated endocytosis of macromolecular conjugates in selective drug delivery
    • Basu, S. K. 1990. Receptor mediated endocytosis of macromolecular conjugates in selective drug delivery. Biochcm. Pharmacol. 40:1941-1946.
    • (1990) Biochcm. Pharmacol. , vol.40 , pp. 1941-1946
    • Basu, S.K.1
  • 5
    • 0027351065 scopus 로고
    • Transfcction of Leishmania and Trypanosoma brucei by electroporation
    • Beverley, S. M., and C. E. Clayton. 1993. Transfcction of Leishmania and Trypanosoma brucei by electroporation. Methods Mol. Biol. 21:333-348.
    • (1993) Methods Mol. Biol. , vol.21 , pp. 333-348
    • Beverley, S.M.1    Clayton, C.E.2
  • 6
    • 0024454057 scopus 로고
    • Characterization of the promastigote surface protease of Leishmania as a membrane bound zinc-endopeptidasc
    • Bouvier, J., C. Bordler, H. Vogel, R. Reichert, and R. Etges. 1989. Characterization of the promastigote surface protease of Leishmania as a membrane bound zinc-endopeptidasc. Mol. Biochcm. Parasitol. 37:235-246.
    • (1989) Mol. Biochcm. Parasitol. , vol.37 , pp. 235-246
    • Bouvier, J.1    Bordler, C.2    Vogel, H.3    Reichert, R.4    Etges, R.5
  • 7
    • 0029046678 scopus 로고
    • Role of Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis
    • Brittlngham, A., C. J. Morrison, W. R. McMaster, B. S. McGwire, K.-P. Chang, and D. M. Mosser, 1995. Role of Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis, J. Immunol. 155:3102-3111.
    • (1995) J. Immunol. , vol.155 , pp. 3102-3111
    • Brittlngham, A.1    Morrison, C.J.2    McMaster, W.R.3    McGwire, B.S.4    Chang, K.-P.5    Mosser, D.M.6
  • 8
    • 0025702766 scopus 로고
    • Atherosclerosis: Scavenging for receptors
    • Brown, M. S, and G. L. Goldstein. 1990. Atherosclerosis: scavenging for receptors. Nature (London) 343:508-509.
    • (1990) Nature (London) , vol.343 , pp. 508-509
    • Brown, M.S.1    Goldstein, G.L.2
  • 9
    • 0015990062 scopus 로고
    • Evidence of an essential histidine residue in thermolysin
    • Burstein, Y., K. A. Walsh, and H. Neurath. 1974. Evidence of an essential histidine residue in thermolysin. Biochemistry 13:205-209.
    • (1974) Biochemistry , vol.13 , pp. 205-209
    • Burstein, Y.1    Walsh, K.A.2    Neurath, H.3
  • 10
    • 0023837354 scopus 로고
    • Molecular cloning of the major surface antigen of Leishmania
    • Button, L. L., and W. R. McMaster. 1988. Molecular cloning of the major surface antigen of Leishmania. J. Exp. Med. 167:724-729.
    • (1988) J. Exp. Med. , vol.167 , pp. 724-729
    • Button, L.L.1    McMaster, W.R.2
  • 11
    • 0027428114 scopus 로고
    • Recombinant Leishmania surface glycoprotein gp63 is secreted in the haculovirus expression system as a latent metalloproteinase
    • Button, L. L., G. Wilson, C. R. Astell, and W. R, McMaster. 1993. Recombinant Leishmania surface glycoprotein gp63 is secreted in the haculovirus expression system as a latent metalloproteinase. Gene 134:75-81.
    • (1993) Gene , vol.134 , pp. 75-81
    • Button, L.L.1    Wilson, G.2    Astell, C.R.3    McMaster, W.R.4
  • 12
    • 0025086308 scopus 로고
    • Molecular determinants of Leishmania virulence
    • Chang, K.-P., G. Chaudhuri, and D. Fong. 1990. Molecular determinants of Leishmania virulence. Annu. Rev. Microbiol, 44:499-529.
    • (1990) Annu. Rev. Microbiol , vol.44 , pp. 499-529
    • Chang, K.-P.1    Chaudhuri, G.2    Fong, D.3
  • 13
    • 0002549642 scopus 로고
    • Biology of Leishmania and leishmuniusis
    • In K.-P. Chang and R. S. Bray (ed.), Elsevier, Amsterdam
    • Chang. K.-P., D. Fong, and R. S. Bray. 1985. Biology of Leishmania and leishmuniusis. p. 1-30. In K.-P. Chang and R. S. Bray (ed.), Leishmaniasis. Elsevier, Amsterdam.
    • (1985) Leishmaniasis , pp. 1-30
    • Chang, K.-P.1    Fong, D.2    Bray, R.S.3
  • 14
    • 0024296398 scopus 로고
    • A simple method for isolation of extnichromosomal circular DNA in unicellular eukaryoles
    • Chaudhuri, G., and K.-P. Chang. 1988. A simple method for isolation of extnichromosomal circular DNA in unicellular eukaryoles. Nucleic Acids Res. 16:2341.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 2341
    • Chaudhuri, G.1    Chang, K.-P.2
  • 15
    • 0023637628 scopus 로고
    • Acid protease activity of a major surface membrane glycoprotein (gp63) from Leishmania mexicana promastigotes
    • Chaudhurl, G., and K.-P. Chang. 1988. Acid protease activity of a major surface membrane glycoprotein (gp63) from Leishmania mexicana promastigotes. Mol. Biochem. Parasitol, 27:43-52.
    • (1988) Mol. Biochem. Parasitol , vol.27 , pp. 43-52
    • Chaudhurl, G.1    Chang, K.-P.2
  • 16
    • 0024509987 scopus 로고
    • Surface acid proteinase (gp63) of Leishmania mexicana: A metalloenzyme capable of protecting liposome-encapsulated proteins from phagolysosomal degradation by macrophages
    • Chaudhuri, G., M. Chaudhuri, A. Pan, and K.-P. Chang. 1989. Surface acid proteinase (gp63) of Leishmania mexicana: a metalloenzyme capable of protecting liposome-encapsulated proteins from phagolysosomal degradation by macrophages. J. Biol. Chem. 264:7483-7489.
    • (1989) J. Biol. Chem. , vol.264 , pp. 7483-7489
    • Chaudhuri, G.1    Chaudhuri, M.2    Pan, A.3    Chang, K.-P.4
  • 17
    • 0024463408 scopus 로고
    • Selective delivery of drugs to macrophages through acetyl low-density lipoprotein receptor: An efficient chemotherapeutic approach against leishmaniasis
    • Chaudhuri, G., A. Mukhopadhyay, and S, K. Basu. 1989. Selective delivery of drugs to macrophages through acetyl low-density lipoprotein receptor: an efficient chemotherapeutic approach against leishmaniasis Biochcm. Pharmacol. 38:2995-3002.
    • (1989) Biochcm. Pharmacol. , vol.38 , pp. 2995-3002
    • Chaudhuri, G.1    Mukhopadhyay, A.2    Basu, S.K.3
  • 19
    • 0027141144 scopus 로고
    • Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guerin expressing the Leishmania surface proteinase gp63
    • Connell, N. D., E. Medina-Acosta, W. R. McMaster, B. R. Bloom, and D. G. Russell. 1993. Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guerin expressing the Leishmania surface proteinase gp63. Proc. Natl. Acad. Sci. USA 90:11473-11477.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11473-11477
    • Connell, N.D.1    Medina-Acosta, E.2    McMaster, W.R.3    Bloom, B.R.4    Russell, D.G.5
  • 20
    • 0027410144 scopus 로고
    • Plasticity in chromosome number and testing of essential genes in Leishmania by targeting
    • Cruz, A, K., R. Titus, and S. M. Beverley. 1993. Plasticity in chromosome number and testing of essential genes in Leishmania by targeting. Proc. Natl. Acad. Sci. USA 90:1599-1603.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1599-1603
    • Cruz, A.K.1    Titus, R.2    Beverley, S.M.3
  • 21
    • 0028859537 scopus 로고
    • A specialized pathway affecting virulence glycoconjugates of Leishmania
    • Descoteaux, A., Y. Luo, S. J. Turco, and S. M. Beverley. 1995. A specialized pathway affecting virulence glycoconjugates of Leishmania. Science 269:1869-1872.
    • (1995) Science , vol.269 , pp. 1869-1872
    • Descoteaux, A.1    Luo, Y.2    Turco, S.J.3    Beverley, S.M.4
  • 22
    • 0023864576 scopus 로고
    • DNA amplification in tunicamycin resistant Leishmania mexicana: Multicopies of a single 63 kilobase supercoiled molecule and their expression
    • Delke, S., U. Chaudhuri, J. A. Kink, and K.-P. Chang. 1988. DNA amplification in tunicamycin resistant Leishmania mexicana: multicopies of a single 63 kilobase supercoiled molecule and their expression. J. Biol. Chem. 263:3418-3424.
    • (1988) J. Biol. Chem. , vol.263 , pp. 3418-3424
    • Delke, S.1    Chaudhuri, U.2    Kink, J.A.3    Chang, K.-P.4
  • 23
    • 0022689973 scopus 로고
    • The major surface protein of Leishmania promastigotes is anchored in the membrane by a myristic acid labeled phospholipid
    • Elges, R., J. Bouvier, and C. Bordler. 1986. The major surface protein of Leishmania promastigotes is anchored in the membrane by a myristic acid labeled phospholipid. EMBO J. 5:597-601.
    • (1986) EMBO J. , vol.5 , pp. 597-601
    • Elges, R.1    Bouvier, J.2    Bordler, C.3
  • 24
    • 0025055580 scopus 로고
    • The major surface glycoprotein (GP63) is present in both life stages of Leishmania
    • Frommel, T. O, L. L. Button, Y. Fujikura, and W. R. McMaster, 1990. The major surface glycoprotein (GP63) is present in both life stages of Leishmania. Mol. Biochem. Parasitol. 38:25-32.
    • (1990) Mol. Biochem. Parasitol. , vol.38 , pp. 25-32
    • Frommel, T.O.1    Button, L.L.2    Fujikura, Y.3    McMaster, W.R.4
  • 25
    • 0021744255 scopus 로고
    • An interactive computer graphics study of thermolysin-catalyzed peptide cleavage and inhibition by N-carboxymethyl dipeptides
    • Hangauer, D. G., A. F. Monzingo, and B. W. Matthews. 1984. An interactive computer graphics study of thermolysin-catalyzed peptide cleavage and inhibition by N-carboxymethyl dipeptides. Biochemistry 23:5730-5741.
    • (1984) Biochemistry , vol.23 , pp. 5730-5741
    • Hangauer, D.G.1    Monzingo, A.F.2    Matthews, B.W.3
  • 26
    • 0027279941 scopus 로고
    • The lysosomal gp63-rclated protein in Leishmania amastigotes is a soluble metalloproteinase with an acidic pH optimum
    • Ilg, T., D. Harbecke, and P. Overath. 1993. The lysosomal gp63-rclated protein in Leishmania amastigotes is a soluble metalloproteinase with an acidic pH optimum. FEBS Lett. 327:103-107.
    • (1993) FEBS Lett. , vol.327 , pp. 103-107
    • Ilg, T.1    Harbecke, D.2    Overath, P.3
  • 27
    • 0025177343 scopus 로고
    • Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils
    • Kodama, T., M. Freeman, L. Rohrer, J. Zabrecky, P. Matsudaira, and M. Krieger. 1990. Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils. Nature (London) 343:531-535.
    • (1990) Nature (London) , vol.343 , pp. 531-535
    • Kodama, T.1    Freeman, M.2    Rohrer, L.3    Zabrecky, J.4    Matsudaira, P.5    Krieger, M.6
  • 28
    • 0024331981 scopus 로고
    • Translation of Leishmania enriettii and expression of chloramphenicol acetyltransferase gene
    • Laban, A., and D. F. Wlrth. 1989. Translation of Leishmania enriettii and expression of chloramphenicol acetyltransferase gene. Proc. Natl. Acad. Sci. USA 86:9119-9123.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9119-9123
    • Laban, A.1    Wlrth, D.F.2
  • 29
    • 0030027824 scopus 로고    scopus 로고
    • An RNA polymerase II promoter in the hsp70 locus of Tiypanosoma brucei
    • Lee, M. G.-S. 1996. An RNA polymerase II promoter in the hsp70 locus of Tiypanosoma brucei. Mol. Cell. Biol. 16:1220-1230.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1220-1230
    • Lee, M.G.-S.1
  • 30
    • 0026777333 scopus 로고
    • Extrachromosomal genetic complementation of surface metalloproteinase (gp63)-deficient Leishmania increases their binding to macrophages
    • Liu, X. and K.-P. Chang. 1992. Extrachromosomal genetic complementation of surface metalloproteinase (gp63)-deficient Leishmania increases their binding to macrophages. Proc. Natl. Acad. Sci. USA 89:4991-4995.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4991-4995
    • Liu, X.1    Chang, K.-P.2
  • 32
    • 0028972393 scopus 로고
    • Analysis of the active site und activation mechanism of the Leishmania surface metalloprotcinasc gp63
    • Macdonald, M. H., C. J. Morrlson, and W. R. McMaster. 1995. Analysis of the active site und activation mechanism of the Leishmania surface metalloprotcinasc gp63. Biochim. Biophys. Acta 1253:199-207.
    • (1995) Biochim. Biophys. Acta , vol.1253 , pp. 199-207
    • Macdonald, M.H.1    Morrlson, C.J.2    McMaster, W.R.3
  • 33
    • 0027240551 scopus 로고
    • Chelation of intracellular zinc triggers apoptosis in mature thymocytes
    • McCabe, M. J., Jr., S. A. Jiang, and S. Orrenius. 1993. Chelation of intracellular zinc triggers apoptosis in mature thymocytes. Lab. Invest. 69:101-110.
    • (1993) Lab. Invest. , vol.69 , pp. 101-110
    • McCabe Jr., M.J.1    Jiang, S.A.2    Orrenius, S.3
  • 34
    • 0028142227 scopus 로고
    • Genetic rescue of surface mctalloproteinase (gp63)-deficicncy in Leishmania amazimensis variants increases their infection of macrophages at the early phase
    • McGwire, B., and K.-P. Chang. 1994. Genetic rescue of surface mctalloproteinase (gp63)-deficicncy in Leishmania amazimensis variants increases their infection of macrophages at the early phase. Mol. Biochcm. Parasitol. 66:345-347.
    • (1994) Mol. Biochcm. Parasitol. , vol.66 , pp. 345-347
    • McGwire, B.1    Chang, K.-P.2
  • 35
    • 0029873473 scopus 로고    scopus 로고
    • Post-translational regulation of a Leishmania HEXXH metalloproteinase (gp63): The effects of site-specific mutagenesis of catalytic, zinc binding, N-glycosylation, and glycosyl phosphatidyl inositol addition sites on N-terminal end cleavage, intracellular stability, and extracellular exit
    • McGwire, B. S., and K.-P. Chang. 1996. Post-translational regulation of a Leishmania HEXXH metalloproteinase (gp63): the effects of site-specific mutagenesis of catalytic, zinc binding, N-glycosylation, and glycosyl phosphatidyl inositol addition sites on N-terminal end cleavage, intracellular stability, and extracellular exit. J. Biol. Chem. 271:7903-7909.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7903-7909
    • McGwire, B.S.1    Chang, K.-P.2
  • 37
    • 0027982197 scopus 로고
    • Mutational and functional analysis of the Leishmania surface metalloproteinase gp63: Similarities to matrix metalloproteinases
    • McMaster, W. R., C. J, Morrlson, H. Macdonald, and P. B. Joshi. 1994. Mutational and functional analysis of the Leishmania surface metalloproteinase gp63: similarities to matrix metalloproteinases. Parasitology 108:S29-S36.
    • (1994) Parasitology , vol.108
    • McMaster, W.R.1    Morrlson, C.J.2    Macdonald, H.3    Joshi, P.B.4
  • 38
    • 0029050856 scopus 로고
    • Protection against Leishmania major infection in genetically susceptible BALB/c mice by gp63 delivered orally in attenuated Salmonella typhimurium (AroA AroD )
    • McSoriey, S. J., D. Xu, S. N. Chaffield, G. Dougan, and F. Y, Liew. 1995. Protection against Leishmania major infection in genetically susceptible BALB/c mice by gp63 delivered orally in attenuated Salmonella typhimurium (AroA AroD ). Immunology 85:1-7.
    • (1995) Immunology , vol.85 , pp. 1-7
    • McSoriey, S.J.1    Xu, D.2    Chaffield, S.N.3    Dougan, G.4    Liew, F.Y.5
  • 39
    • 0027472098 scopus 로고
    • Structurally distinct genes for the surface protease of Leishmania mexicana arc developmentally regulated
    • Medlna-Acusta, E., R. E, Karess, and D. G. Russell. 1993. Structurally distinct genes for the surface protease of Leishmania mexicana arc developmentally regulated. Mol. Biochem. Parasitol. 57:31-45.
    • (1993) Mol. Biochem. Parasitol. , vol.57 , pp. 31-45
    • Medlna-Acusta, E.1    Karess, R.E.2    Russell, D.G.3
  • 40
    • 0024439986 scopus 로고
    • The promastigote surface protease (gp63) at Leishmania is expressed but differ- Cntly processed and localized in the amastigote stage
    • Medina-Acosta, E., R. E. Karess, H. Schwartz, and D. G. Russell, 1989. The promastigote surface protease (gp63) at Leishmania is expressed but differ- cntly processed and localized in the amastigote stage. Mol. Biochem. Parasitol. 37:263-274.
    • (1989) Mol. Biochem. Parasitol. , vol.37 , pp. 263-274
    • Medina-Acosta, E.1    Karess, R.E.2    Schwartz, H.3    Russell, D.G.4
  • 41
    • 0025138718 scopus 로고
    • Leishmania gp63 molecule implicated in cellular adhesion lacks an Arg-Gly-Asp sequence
    • Miller, R. A., S. G. Reed, and M. Parsons. 1990. Leishmania gp63 molecule implicated in cellular adhesion lacks an Arg-Gly-Asp sequence. Mol. Bioehem. Parasitol. 39:267-274.
    • (1990) Mol. Bioehem. Parasitol. , vol.39 , pp. 267-274
    • Miller, R.A.1    Reed, S.G.2    Parsons, M.3
  • 42
    • 0024355351 scopus 로고
    • Receptor-medialed drug delivery to macrophages in chemotherapy of leishmaniusis
    • Mukhopadhyay, A., G. Chaudhuri, S, K. Arora, S. Bengal, and S. K. Basu. 1989. Receptor-medialed drug delivery to macrophages in chemotherapy of leishmaniusis. Science 244:705-707.
    • (1989) Science , vol.244 , pp. 705-707
    • Mukhopadhyay, A.1    Chaudhuri, G.2    Arora, S.K.3    Bengal, S.4    Basu, S.K.5
  • 43
    • 0026582754 scopus 로고
    • Scavenger-receptor-mediated delivery of daunomycin clicits selective toxicity towards neoplastic cells of macrophage lineage
    • Mukhopadhyay, A., B. Mukhopadhyay, R. K. Srivastava, and S. K, Basu. 1992. Scavenger-receptor-mediated delivery of daunomycin clicits selective toxicity towards neoplastic cells of macrophage lineage. Biochem. J. 284:237-241.
    • (1992) Biochem. J. , vol.284 , pp. 237-241
    • Mukhopadhyay, A.1    Mukhopadhyay, B.2    Srivastava, R.K.3    Basu, S.K.4
  • 44
    • 0021869320 scopus 로고
    • Enhanced metabolism of Leishmania dimovtni amastigotes at acid pH: An adaptation for intracellular growth
    • Mukkada, A. J., J. C. Meade, T. A. Glaser, and P. Bonventre. 1985. Enhanced metabolism of Leishmania dimovtni amastigotes at acid pH: an adaptation for intracellular growth. Science 229:1099-1101.
    • (1985) Science , vol.229 , pp. 1099-1101
    • Mukkada, A.J.1    Meade, J.C.2    Glaser, T.A.3    Bonventre, P.4
  • 45
    • 0027221830 scopus 로고
    • Metal chelators reverse the action of hydrogen peroxide in rat leutal cells
    • Musicki, B., and H. R. Behrman. 1993. Metal chelators reverse the action of hydrogen peroxide in rat leutal cells. Mol. Cell. Endocrinol. 92:215-220.
    • (1993) Mol. Cell. Endocrinol. , vol.92 , pp. 215-220
    • Musicki, B.1    Behrman, H.R.2
  • 46
    • 0029012720 scopus 로고
    • Intergenic regions between tandem gp63 genes influence the differential expression of gpA3 RNAs in Leishmania chagasi pnomastigotes
    • Romamoorthy, R., K. G. Swlhart, J. J. McCoy, M. E. Wilson, and J. E. Donelson. 1995. Intergenic regions between tandem gp63 genes influence the differential expression of gpA3 RNAs in Leishmania chagasi pnomastigotes, J. Biol. Chem. 270:12133-12139.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12133-12139
    • Romamoorthy, R.1    Swlhart, K.G.2    McCoy, J.J.3    Wilson, M.E.4    Donelson, J.E.5
  • 48
    • 0028933057 scopus 로고
    • Developmentally regulated expression of a novel 59-kDa product of the major surface protease (Map or gp63) gene family of Leishmania chagasi
    • Roberts, S. C., M. E. Wilson, and J. E. Donelson. 1995. Developmentally regulated expression of a novel 59-kDa product of the major surface protease (Map or gp63) gene family of Leishmania chagasi. J. Biol. Chcm. 270:8884-8892.
    • (1995) J. Biol. Chcm. , vol.270 , pp. 8884-8892
    • Roberts, S.C.1    Wilson, M.E.2    Donelson, J.E.3
  • 49
    • 0027153185 scopus 로고
    • Mapping human T-cell epitopes in Leishmania gp63: Identification of cross-reactive and species-specific epitopes
    • RUSSo, U. M., A. Jardim, E. M, Carvalho, P. R. Sleuth, R, J. Armitage. R. W. Olafson, and S, G. Reed. 1993. Mapping human T-cell epitopes in Leishmania gp63: identification of cross-reactive and species-specific epitopes. J. Immunol. 150:932-939.
    • (1993) J. Immunol. , vol.150 , pp. 932-939
    • Russo, U.M.1    Jardim, A.2    Carvalho, E.M.3    Sleuth, P.R.4    Armitage, R.J.5    Olafson, R.W.6    Reed, S.G.7
  • 50
    • 0027227645 scopus 로고
    • Isolation of virulenee genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania
    • Ryan, K. A., L. A. Garraway, A. Descoteaux, K. J. Turco, and S, M. Beverley. 1993 Isolation of virulenee genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania. Proc. Natl. Acad. Sci. USA 90:8609-8613.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8609-8613
    • Ryan, K.A.1    Garraway, L.A.2    Descoteaux, A.3    Turco, K.J.4    Beverley, S.M.5
  • 51
    • 0027487851 scopus 로고
    • Reversion to virulence in Leishmania major correlates with expression of surface lipophosphoglycan
    • Sankar, A., T. K. Milchen, L. R. Hall, S. J. Turco, and R. G. Tltus. 1993. Reversion to virulence in Leishmania major correlates with expression of surface lipophosphoglycan. Mol. Biochem. Parasitol. 61:207-216.
    • (1993) Mol. Biochem. Parasitol. , vol.61 , pp. 207-216
    • Sankar, A.1    Milchen, T.K.2    Hall, L.R.3    Turco, S.J.4    Tltus, R.G.5
  • 52
    • 0026918044 scopus 로고
    • Leishmania major differential regulation of the surface metalloprotease in amastigole and promastigote stages
    • Schneider, P., J. P. Rosar, J. Bouvier, J. Louis, and C. Bordler. 1992. Leishmania major differential regulation of the surface metalloprotease in amastigole and promastigote stages. Parasitology 75:196-206.
    • (1992) Parasitology , vol.75 , pp. 196-206
    • Schneider, P.1    Rosar, J.P.2    Bouvier, J.3    Louis, J.4    Bordler, C.5
  • 53
    • 0027455633 scopus 로고
    • Antibody responses to visceral leishmaniasis patients to gp63, a major surface glycoprotein of Leishmania species
    • Shreffler, W. G., J. M. Burns, R, Badaro, H. W. Ghallb, L. L. Button, W. R, McMaster, and S. G. Reed. 1993. Antibody responses to visceral leishmaniasis patients to gp63, a major surface glycoprotein of Leishmania species, J. Infect. Dis. 167:426-430.
    • (1993) J. Infect. Dis. , vol.167 , pp. 426-430
    • Shreffler, W.G.1    Burns, J.M.2    Badaro, R.3    Ghallb, H.W.4    Button, L.L.5    McMaster, W.R.6    Reed, S.G.7
  • 55
    • 0027475170 scopus 로고
    • PCR MIMICS: Competitive DNA fragments for use as internal standards in quantitative PCR
    • Slebert, P. D., and J. W. Larrlck. 1993. PCR MIMICS: competitive DNA fragments for use as internal standards in quantitative PCR. BioTechniques 14:244-249.
    • (1993) BioTechniques , vol.14 , pp. 244-249
    • Slebert, P.D.1    Larrlck, J.W.2
  • 57
    • 0028309901 scopus 로고
    • The gel shift assay for the analysis of DNA-protein interactions
    • G. G. Kneale (cd.), Humana Press. Clifton, N.J.
    • Taylor, J. D., A. J. Ackroyd, and S. E. Haiford. 1994. The gel shift assay for the analysis of DNA-protein interactions, p. 263-279. In G. G. Kneale (cd.), DNA-protein interactions. Humana Press. Clifton, N.J.
    • (1994) DNA-protein Interactions , pp. 263-279
    • Taylor, J.D.1    Ackroyd, A.J.2    Haiford, S.E.3
  • 58
    • 0026746610 scopus 로고
    • The lipophosphuglycan of Leishmania parasites
    • Turco, S. J., and A. Descoleaux. 1992. The lipophosphuglycan of Leishmania parasites. Annu. Rev. Microbiol. 46:65-94,
    • (1992) Annu. Rev. Microbiol. , vol.46 , pp. 65-94
    • Turco, S.J.1    Descoleaux, A.2
  • 59
    • 0025810812 scopus 로고
    • Substrate-dependent pH optima of gp63 purified from seven strains of Leishmania
    • Tzinia, A. K., and K. P. Soterladou. 1991. Substrate-dependent pH optima of gp63 purified from seven strains of Leishmania. Mol. Biochcm. Parasitol. 47: 83-89.
    • (1991) Mol. Biochcm. Parasitol. , vol.47 , pp. 83-89
    • Tzinia, A.K.1    Soterladou, K.P.2
  • 60
    • 0027322425 scopus 로고
    • Molecular cloning and expression of a Leismania major gene encoding a single-stranded DNA-binding protein containing nine CCHC zinc finger motifs
    • Webb, J. B, and W. R. McMaster. 1993. Molecular cloning and expression of a Leismania major gene encoding a single-stranded DNA-binding protein containing nine CCHC zinc finger motifs. J. Biol. Chem. 268:13994-14002.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13994-14002
    • Webb, J.B.1    McMaster, W.R.2
  • 61
    • 0028326573 scopus 로고
    • Lcishmania major HEXBP deletion mutants generated by double targeted gene replacement
    • Webb, J. B., and W. R. McMaster. 1994. Lcishmania major HEXBP deletion mutants generated by double targeted gene replacement. Mol., Biochem. Parasitol. 63:231-242.
    • (1994) Mol., Biochem. Parasitol. , vol.63 , pp. 231-242
    • Webb, J.B.1    McMaster, W.R.2
  • 62
    • 0027306112 scopus 로고
    • The effect of ongoing protein synthesis on the steady state levels of gp63 RNAs in Leishmania chagusi
    • Wilson, M. E., K. E. Paeiz, R. Ramamoorthy, and J. E. Donelson. 1993. The effect of ongoing protein synthesis on the steady state levels of gp63 RNAs in Leishmania chagusi. J. Biol. Chem. 268:15731-15736.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15731-15736
    • Wilson, M.E.1    Paeiz, K.E.2    Ramamoorthy, R.3    Donelson, J.E.4


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