Mutations of the transforming growth factor-β type II receptor gene are strongly related to sporadic proximal colon carcinomas with microsatellite instability

Cancer

Volumn 78, Issue 12, 1996, Pages 2478-2484

  Akiyama, Yoshimitsu ^a   Iwanaga, Ritsuko ^a   Ishikawa, Tomoko ^a   Sakamoto, Kosaku ^b   Nishi, Naoto ^a   Nihei, Zenro ^a   Iwama, Takeo ^a   Saitoh, Kiyoshi ^c   Yuasa, Yasuhito ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Sakamoto Clinic of Gastroenterology   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

colon carcinoma; hereditary nonpolyposis colorectal carcinoma; hMLH1; hMSH2; microsatellite instability; TGF receptor

Indexed keywords

MICROSATELLITE DNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ADULT; AGED; ARTICLE; ASCENDING COLON; COLORECTAL CARCINOMA; FEMALE; FRAMESHIFT MUTATION; GENE DELETION; GENE MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEPTOR GENE; SOMATIC MUTATION;

AGED; AGED, 80 AND OVER; COLONIC NEOPLASMS; DNA, SATELLITE; FEMALE; HUMANS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA;

EID: 0029851548     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19961215)78:12<2478::AID-CNCR5>3.0.CO;2-G     Document Type: Article

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