An evaluation of the roles of metabolic denitrosation and α- hydroxylation in the hepatotoxicity of N-nitrosodimethylamine

Chemical Research in Toxicology

Volumn 9, Issue 8, 1996, Pages 1319-1324

  Lee, Valentia M ^a   Keefer, Larry K ^b   Archer, Michael C ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLNITROSAMINE; FORMALDEHYDE; METHANOL; METHYLAMINE; N ACETOXYMETHYL N METHYLNITROSAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL PROLIFERATION; HYDROXYLATION; LIVER CELL; LIVER TOXICITY; MUTAGENESIS; NITROSATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN BINDING; RAT;

ANIMALS; CARCINOGENS; CELL SURVIVAL; CELLS, CULTURED; HEPATITIS, TOXIC; HYDROXYLATION; L-LACTATE DEHYDROGENASE; LIVER; MALE; NITROSO COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SWINE;

ANIMALIA;

EID: 0029851429     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx960077u     Document Type: Article

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