-
1
-
-
0023332815
-
Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves
-
Stead RH, Tomioka M, Quinonez G, Simon GT, Felten SY, Bienenstock J: Intestinal mucosal mast cells In normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves. Proc Natl Acad Sci U S A 1987, 84:2975-2979.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 2975-2979
-
-
Stead, R.H.1
Tomioka, M.2
Quinonez, G.3
Simon, G.T.4
Felten, S.Y.5
Bienenstock, J.6
-
2
-
-
0028855946
-
Eicosanoids and histamine mediate C5a-induced electrolyte secretion in guinea pig ileal mucosa
-
Kachur JF, Wonkim S, Anglin C, Gaginella TS: Eicosanoids and histamine mediate C5a-induced electrolyte secretion in guinea pig ileal mucosa. Inflammation 1995, 19:717-725.
-
(1995)
Inflammation
, vol.19
, pp. 717-725
-
-
Kachur, J.F.1
Wonkim, S.2
Anglin, C.3
Gaginella, T.S.4
-
3
-
-
0028059920
-
Integrative immunophysiology in the intestinal mucosa
-
Perdue MH, McKay DM: Integrative immunophysiology in the intestinal mucosa. Am J Physiol 1994, 267:G151-G165.
-
(1994)
Am J Physiol
, vol.267
-
-
Perdue, M.H.1
McKay, D.M.2
-
4
-
-
0029049716
-
Mast cells and histamine contribute to bile acid-stimulated secretion in the mouse colon
-
Gelbmann CM, Schteingart CD, Thompson SM, Hofmann AF, Barrett KE: Mast cells and histamine contribute to bile acid-stimulated secretion in the mouse colon. J Clin Invest 1995, 95:2831-2839. This study implicates mast cells as the mechanism responsible for the secretory effects of bile acids in the mouse large intestine.
-
(1995)
J Clin Invest
, vol.95
, pp. 2831-2839
-
-
Gelbmann, C.M.1
Schteingart, C.D.2
Thompson, S.M.3
Hofmann, A.F.4
Barrett, K.E.5
-
7
-
-
0030042527
-
Mast cells mediate acid-induced augmentation of opossum esophageal blood flow via histamine and nitric oxide
-
Feldman MJ, Morris GP, Dinda PK, Paterson WG: Mast cells mediate acid-induced augmentation of opossum esophageal blood flow via histamine and nitric oxide. Gastroenterology 1996, 110:121-128.
-
(1996)
Gastroenterology
, vol.110
, pp. 121-128
-
-
Feldman, M.J.1
Morris, G.P.2
Dinda, P.K.3
Paterson, W.G.4
-
8
-
-
0030021721
-
Mucosal T cells and mast cells share common adhesion receptors
-
Smith TJ, Weis JH: Mucosal T cells and mast cells share common adhesion receptors. Immunol Today 1996, 17:60-63.
-
(1996)
Immunol Today
, vol.17
, pp. 60-63
-
-
Smith, T.J.1
Weis, J.H.2
-
9
-
-
0028675005
-
Interactions between stem cell factor and c-kit are required for intestinal immune system homeostasis
-
Puddington L, Olson S, Lefrancois L: Interactions between stem cell factor and c-kit are required for intestinal immune system homeostasis. Immunity 1994, 1:733-739.
-
(1994)
Immunity
, vol.1
, pp. 733-739
-
-
Puddington, L.1
Olson, S.2
Lefrancois, L.3
-
10
-
-
0028817939
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A role for stem cell factor and c-kit in the murine intestinal tract secretory response to cholera toxin
-
Kumpel GR, Chopra AK, Langley KE, Wypych J, Annable CA, Kaiserlian D, Ernst PB, Peterson JW: A role for stem cell factor and c-kit in the murine intestinal tract secretory response to cholera toxin. J Exp Med 1995, 182:1931-1942. This study found that stem cell factor is released into secreted fluid stimulated by cholera toxin in mouse small intestine. In addition, a mouse epithelial cell line was shown to express stem cell factor after exposure to cholera toxin.
-
(1995)
J Exp Med
, vol.182
, pp. 1931-1942
-
-
Kumpel, G.R.1
Chopra, A.K.2
Langley, K.E.3
Wypych, J.4
Annable, C.A.5
Kaiserlian, D.6
Ernst, P.B.7
Peterson, J.W.8
-
11
-
-
0029126855
-
Regulation of arachidonic acid, eicosanoid, and phospholipase A2 levels in murine mast cells by recombinant stem cell factor
-
Fonteh AN, Samet JM, Chilton FH: Regulation of arachidonic acid, eicosanoid, and phospholipase A2 levels In murine mast cells by recombinant stem cell factor. J Clin Invest 1995, 96:1432-1439.
-
(1995)
J Clin Invest
, vol.96
, pp. 1432-1439
-
-
Fonteh, A.N.1
Samet, J.M.2
Chilton, F.H.3
-
12
-
-
0027219061
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Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum
-
Pothoulakis C, Karmeli F, Kelly CP, Eliakim R, Joshi MA, O'Keane CJ, Castagliuolo I, Lamont JT, Rachmilewitz D: Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum. Gastroenterology 1993, 105:701-707.
-
(1993)
Gastroenterology
, vol.105
, pp. 701-707
-
-
Pothoulakis, C.1
Karmeli, F.2
Kelly, C.P.3
Eliakim, R.4
Joshi, M.A.5
O'Keane, C.J.6
Castagliuolo, I.7
Lamont, J.T.8
Rachmilewitz, D.9
-
13
-
-
0030032558
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Mast cell tryptase is a mitogen for epithelial cells. Stimulation of IL-8 production and intracellular adhesion molecule-1 expression
-
Cairns JA, Walls AF: Mast cell tryptase is a mitogen for epithelial cells. Stimulation of IL-8 production and intracellular adhesion molecule-1 expression. J Immunol 1996, 156:275-283. This paper reports that mast cells release tryptase during activation, which stimulates proliferation of airway epithelial cells and induces epithelial production of IL-8 and expression of intracellular adhesion molecule-1.
-
(1996)
J Immunol
, vol.156
, pp. 275-283
-
-
Cairns, J.A.1
Walls, A.F.2
-
14
-
-
0028820753
-
Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep
-
Clark JM, Abraham WM, Fishman CE, Forteza R, Ahmed A, Cortes A, Warne RL, Moore WR, Tanaka RD: Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep. Am J Respir Crit Care Med 1995, 152:2076-2083.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 2076-2083
-
-
Clark, J.M.1
Abraham, W.M.2
Fishman, C.E.3
Forteza, R.4
Ahmed, A.5
Cortes, A.6
Warne, R.L.7
Moore, W.R.8
Tanaka, R.D.9
-
15
-
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0028819780
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Release of mucosal mast cell granule chymase, rat mast cell protease-II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat Jejunum
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Scudmore CL, Thornton EM, McMillan L, Newlands GFJ, Miller HRP: Release of mucosal mast cell granule chymase, rat mast cell protease-II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat Jejunum. J Exp Med 1995, 182:1871-1881. This study demonstrates that when infused into the intestinal circulation, the protease of rat intestinal mucosal mast cells rapidly increases epithelial permeability.
-
(1995)
J Exp Med
, vol.182
, pp. 1871-1881
-
-
Scudmore, C.L.1
Thornton, E.M.2
McMillan, L.3
Newlands, G.F.J.4
Miller, H.R.P.5
-
16
-
-
0026737317
-
Gastrointestinal food hypersensitivity: Basic mechanisms of pathophysiology
-
Crowe SE, Perdue MH: Gastrointestinal food hypersensitivity: basic mechanisms of pathophysiology. Gastroenterology 1992, 103:1075-1095.
-
(1992)
Gastroenterology
, vol.103
, pp. 1075-1095
-
-
Crowe, S.E.1
Perdue, M.H.2
-
17
-
-
0029960010
-
Platelet activating factor: Release from colonic mucosa in patients with ulcerative colitis and its effect on colonic secretion
-
Wardle TD, Hall L, Turnberg LA: Platelet activating factor: release from colonic mucosa in patients with ulcerative colitis and its effect on colonic secretion. Gut 1996, 38:355-361.
-
(1996)
Gut
, vol.38
, pp. 355-361
-
-
Wardle, T.D.1
Hall, L.2
Turnberg, L.A.3
-
18
-
-
0029863465
-
Mast cell-dependent neutrophil and mononuclear cell recruitment in immunoglobulin E-induced gastric reactions in mice
-
Wershil BK, Furuta GT, Wang ZS, Galli SJ: Mast cell-dependent neutrophil and mononuclear cell recruitment in immunoglobulin E-induced gastric reactions in mice. Gastroenterology 1996, 110:1482-1490. is study demonstrates the key role of mast cells in the recruitment of inflammatory cells to gastric mucosa following antigen challenge and provides evidence for a late-phase response in the gastrointestinal tract.
-
(1996)
Gastroenterology
, vol.110
, pp. 1482-1490
-
-
Wershil, B.K.1
Furuta, G.T.2
Wang, Z.S.3
Galli, S.J.4
-
19
-
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0028215642
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Role of H1 receptors and p-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venules
-
Asako H, Kurose I, Wolf R, DeFrees S, Zheng Z-L, Phillips ML, Paulson JC, Granger DN: Role of H1 receptors and p-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venules. J Clin Invest 1994, 93:1508-1515.
-
(1994)
J Clin Invest
, vol.93
, pp. 1508-1515
-
-
Asako, H.1
Kurose, I.2
Wolf, R.3
DeFrees, S.4
Zheng, Z.-L.5
Phillips, M.L.6
Paulson, J.C.7
Granger, D.N.8
-
20
-
-
0029037745
-
Boosted systemic immune and local responsiveness after intestinal inflammation in orally sensitized guinea pigs
-
Fargeas M-J, Theodorou V, More J, Wal J-M, Fioramonti J, Bueno L: Boosted systemic immune and local responsiveness after intestinal inflammation in orally sensitized guinea pigs. Gastroenterology 1995, 109:53-62. This study shows that increased epithelial permeability, caused by TNBS inflammation in the proximal small intestine, results in a greater degree of sensitization in guinea pigs following drinking of cow's milk than in nontreated guinea pigs. Subsequent colonic antigen challenge results in greater ion secretion in those guinea pigs compared with the control group. Therefore, this study suggests that epithelial barrier defects may have significant consequences.
-
(1995)
Gastroenterology
, vol.109
, pp. 53-62
-
-
Fargeas, M.-J.1
Theodorou, V.2
More, J.3
Wal, J.-M.4
Fioramonti, J.5
Bueno, L.6
-
21
-
-
0029123521
-
Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis
-
Mantyh CR, Vigna SR, Bollinger RR, Mantyh PW, Maggio JE, Pappas TN: Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis. Gastroenterology 1995, 109:850-860.
-
(1995)
Gastroenterology
, vol.109
, pp. 850-860
-
-
Mantyh, C.R.1
Vigna, S.R.2
Bollinger, R.R.3
Mantyh, P.W.4
Maggio, J.E.5
Pappas, T.N.6
-
22
-
-
0030063285
-
Action of sensory neurons in an experimental rat colitis model of injury and repair
-
Reinshagen M, Patel A, Sottili M, French S, Sternini C, Eysselein VE: Action of sensory neurons in an experimental rat colitis model of injury and repair. Am J Physiol 1996, 270:G79-G86.
-
(1996)
Am J Physiol
, vol.270
-
-
Reinshagen, M.1
Patel, A.2
Sottili, M.3
French, S.4
Sternini, C.5
Eysselein, V.E.6
-
23
-
-
0028543664
-
Substance-P mediated intestinal inflammation: Inhibitory effects of CP 96,345 and SMS 201-995
-
Kataeva G, Agro A, Stanisz A: Substance-P mediated intestinal inflammation: inhibitory effects of CP 96,345 and SMS 201-995. Neuroimmunomodulation 1994, 1:350-356.
-
(1994)
Neuroimmunomodulation
, vol.1
, pp. 350-356
-
-
Kataeva, G.1
Agro, A.2
Stanisz, A.3
-
25
-
-
0028967388
-
Human eosinophils migrate across an intestinal epithelium in response to platelet-activating factor
-
Resnick MB, Colgan SP, Parkas CA, Delp-Archer C, McGuirk D, Weller PF, Madara JL: Human eosinophils migrate across an intestinal epithelium in response to platelet-activating factor. Gastroenterology 1995, 108:409-416.
-
(1995)
Gastroenterology
, vol.108
, pp. 409-416
-
-
Resnick, M.B.1
Colgan, S.P.2
Parkas, C.A.3
Delp-Archer, C.4
McGuirk, D.5
Weller, P.F.6
Madara, J.L.7
-
26
-
-
0030046975
-
Intestinal inflammation in children with atopic eczema: Faecal eosinophil cationic protein and tumor necrosis factor-alpha as non-invasive indicators of food allergy
-
Majamaa H, Miettinen A, Laine S, Isolauri E: Intestinal inflammation in children with atopic eczema: Faecal eosinophil cationic protein and tumor necrosis factor-alpha as non-invasive indicators of food allergy. Clin Exp Allergy 1996, 26:181-187.
-
(1996)
Clin Exp Allergy
, vol.26
, pp. 181-187
-
-
Majamaa, H.1
Miettinen, A.2
Laine, S.3
Isolauri, E.4
-
27
-
-
0028228827
-
Mononuclear cells from infants allergic to cow's milk secrete tumor necrosis factor alpha, altering intestinal function
-
Heymen M, Darmon N, Dupont C, Dugas B, Hirribaren A, Blaton M-A, Desjeux J-F: Mononuclear cells from infants allergic to cow's milk secrete tumor necrosis factor alpha, altering intestinal function. Gastroenterology 1994, 106:1514-1523.
-
(1994)
Gastroenterology
, vol.106
, pp. 1514-1523
-
-
Heymen, M.1
Darmon, N.2
Dupont, C.3
Dugas, B.4
Hirribaren, A.5
Blaton, M.-A.6
Desjeux, J.-F.7
-
28
-
-
0028236232
-
Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease
-
Breese EJ, Michie CA, Nicholls SW, Murch SH, Williams CB, Domizio P, Walkersmith JA, MacDonald TT: Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 1994, 106:1455-1466.
-
(1994)
Gastroenterology
, vol.106
, pp. 1455-1466
-
-
Breese, E.J.1
Michie, C.A.2
Nicholls, S.W.3
Murch, S.H.4
Williams, C.B.5
Domizio, P.6
Walkersmith, J.A.7
MacDonald, T.T.8
-
29
-
-
0030045392
-
Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 in eosinophilic gastroenteritis
-
Desreumaux P, Bloget F, Seguy D, Capron M, Cortot A, Colombel J-F, Janin A: Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 in eosinophilic gastroenteritis. Gastroenterology 1996, 110:768-774.
-
(1996)
Gastroenterology
, vol.110
, pp. 768-774
-
-
Desreumaux, P.1
Bloget, F.2
Seguy, D.3
Capron, M.4
Cortot, A.5
Colombel, J.-F.6
Janin, A.7
-
30
-
-
0029888615
-
Eosinophil fibroblast Interactions: Granule major basic protein interacts with IL-1 and transforming growth factor β in the stimulation of lung fibroblast IL-6-type cytokine production
-
Rochester C, Ackerman S, Zheng T, Elias J: Eosinophil fibroblast Interactions: granule major basic protein interacts with IL-1 and transforming growth factor β in the stimulation of lung fibroblast IL-6-type cytokine production. J Immunol 1996, 156:4449-4456.
-
(1996)
J Immunol
, vol.156
, pp. 4449-4456
-
-
Rochester, C.1
Ackerman, S.2
Zheng, T.3
Elias, J.4
-
31
-
-
0027258364
-
5'-Adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers
-
Madara JL, Palapoff TW, Gillece-Castro B, Colgan SP, Parkas CA, Delp C, Mrsny RJ: 5'-Adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers. J Clin Invest 1993, 91:2320-2325.
-
(1993)
J Clin Invest
, vol.91
, pp. 2320-2325
-
-
Madara, J.L.1
Palapoff, T.W.2
Gillece-Castro, B.3
Colgan, S.P.4
Parkas, C.A.5
Delp, C.6
Mrsny, R.J.7
-
32
-
-
0028919437
-
Intestinal epithelia (TB4) possess basolateral ligands for CD11b/CD18-mediated neutrophil adherence
-
Parkas CA, Colgan SP, Bacarra AE, Nusrat A, Delp-Archer C, Carlson S, Su DHC, Madara JL: Intestinal epithelia (TB4) possess basolateral ligands for CD11b/CD18-mediated neutrophil adherence. Am J Physiol 1995, 268:C472-C479.
-
(1995)
Am J Physiol
, vol.268
-
-
Parkas, C.A.1
Colgan, S.P.2
Bacarra, A.E.3
Nusrat, A.4
Delp-Archer, C.5
Carlson, S.6
Su, D.H.C.7
Madara, J.L.8
-
33
-
-
0028864991
-
A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
-
Jung HC, Eckmann L, Yang S, Panja A, Fierer J, Morzycka-Wroblewska E, Kagnoff MF: A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 1995, 95:55-65. This study demonstrates that bacterial invasion of epithelial cells results in expression of cytokines, particularly IL-B (which has chemotactic properties), suggesting that epithelial cells participate in inflammatory reactions.
-
(1995)
J Clin Invest
, vol.95
, pp. 55-65
-
-
Jung, H.C.1
Eckmann, L.2
Yang, S.3
Panja, A.4
Fierer, J.5
Morzycka-Wroblewska, E.6
Kagnoff, M.F.7
-
34
-
-
0029609245
-
Surface attachment of Salmonella typhimurium to intestinal epithelia prints the subepithelial matrix with gradients chemotactic for neutrophils
-
McCormick BA, Hofman PM, Kim J, Carnes DK, Miller SI, Madara JL: Surface attachment of Salmonella typhimurium to intestinal epithelia prints the subepithelial matrix with gradients chemotactic for neutrophils. J Cell Biol 1995, 131:1599-1608. This paper provides evidence that bacterial interactions with epithelial cells result in transfer of chemotactic properties to the matrix so that it retains the ability to attract neutrophils even in the absence of epithelial cells.
-
(1995)
J Cell Biol
, vol.131
, pp. 1599-1608
-
-
McCormick, B.A.1
Hofman, P.M.2
Kim, J.3
Carnes, D.K.4
Miller, S.I.5
Madara, J.L.6
-
35
-
-
0029056024
-
+ population of monocytes in inflammatory bowel disease mucosa-implications for pathogenesis
-
+ population of monocytes in inflammatory bowel disease mucosa-implications for pathogenesis. Clin Exp Immunol 1995, 100:291-297. This study demonstrates that circulating monocytes are recruited to the intestinal mucosa of patients with IBD. The expression of CD14 on the surface of these cells makes them reactive to bacterial endotoxin, unlike the relatively unresponsive macrophages found in intestine of healthy individuals.
-
(1995)
Clin Exp Immunol
, vol.100
, pp. 291-297
-
-
Grimm, M.C.1
Pavli, P.2
Van De Pol, E.3
Doe, W.F.4
-
36
-
-
0028813487
-
Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa
-
Reinecker H-C, Loh EY, Ringler DJ, Mehta A, Rombeau JL, MacDermott RP: Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa. Gastroenterology 1995, 108:40-50. This paper demonstrates that intestinal epithelial cells in IBD express a chemokine for monocytes. This may explain the presence of monocytes in the mucosa of these patients [35•].
-
(1995)
Gastroenterology
, vol.108
, pp. 40-50
-
-
Reinecker, H.-C.1
Loh, E.Y.2
Ringler, D.J.3
Mehta, A.4
Rombeau, J.L.5
MacDermott, R.P.6
-
37
-
-
0029586031
-
Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
-
Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, Zumbuschenfelde KHM: Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 1995, 102:448-455. This study shows that both blood and intestinal mononuclear cells from patients with IBD respond to their own intestinal flora, unlike the normal situation in the gut (tolerance of autologous bacteria).
-
(1995)
Clin Exp Immunol
, vol.102
, pp. 448-455
-
-
Duchmann, R.1
Kaiser, I.2
Hermann, E.3
Mayet, W.4
Ewe, K.5
Zumbuschenfelde, K.H.M.6
-
38
-
-
0030012072
-
T cell-monocyte interactions regulate epithelial physiology in a co-culture model of inflammation
-
McKay DM, Croitoru K, Perdue MH: T cell-monocyte interactions regulate epithelial physiology in a co-culture model of inflammation. Am J Physiol 1996, 270:C418-C428. This study illustrates T-cell-to-monocyte communication in the induction of epithelial transport and permeability abnormalities. Experimental evidence is presented showing that specific T-cell activation leads to the release of IFN-γ, which activates monocytes, causing TNF-α production. This intercellular signaling results in epithelial pathophysiology in the absence of major cytotoxic effect.
-
(1996)
Am J Physiol
, vol.270
-
-
McKay, D.M.1
Croitoru, K.2
Perdue, M.H.3
-
39
-
-
0342936960
-
Intestinal inflammation induced by non-pathogenic non-toxigenic E. coli
-
Zareie M, McKay DM, Brattsand R, Philpott D, Sherman P, Perdue MH: Intestinal inflammation induced by non-pathogenic non-toxigenic E. coli [abstract]. Gastroenterology 1996, 110:1052.
-
(1996)
Gastroenterology
, vol.110
, pp. 1052
-
-
Zareie, M.1
McKay, D.M.2
Brattsand, R.3
Philpott, D.4
Sherman, P.5
Perdue, M.H.6
-
40
-
-
0030423740
-
Budesonide inhibits T cell-initiated epithelial pathophysiology in an in vitro model of inflammation
-
McKay DM, Brattsand R, Wieslander E, Fung M, Croitoru K, Perdue MH: Budesonide inhibits T cell-initiated epithelial pathophysiology in an in vitro model of inflammation. J Pharmacol Exp Ther 1996, 277:403-410. This paper shows that T cells or monocytes pretreated with budesonide prior to activation prevent the epithelial transport and barrier abnormalities evoked by coculture with these immune cells.
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 403-410
-
-
McKay, D.M.1
Brattsand, R.2
Wieslander, E.3
Fung, M.4
Croitoru, K.5
Perdue, M.H.6
-
41
-
-
0027398111
-
Regulation of antigen-presenting cell function(s) in lung and airway tissues
-
Holt PG: Regulation of antigen-presenting cell function(s) in lung and airway tissues. Eur Respir J 1993, 6:120-129.
-
(1993)
Eur Respir J
, vol.6
, pp. 120-129
-
-
Holt, P.G.1
-
42
-
-
0030022290
-
Class II MHC antigen (Ia)- Bearing dendritic cells in the epithelium of the rat
-
Maric I, Holt PG, Perdue MH, Bienenstock J: Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat J Immunol 1996, 156:1408-1414. This paper clearly demonstrates the presence of a network of dendritic cells in the mucosa of rat small and large intestine. These cells may be located in the epithelium or may extend processes between tight junctions, suggesting that they have exposure to luminal contents.
-
(1996)
J Immunol
, vol.156
, pp. 1408-1414
-
-
Maric, I.1
Holt, P.G.2
Perdue, M.H.3
Bienenstock, J.4
-
43
-
-
0030067796
-
Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Payer's patch
-
Kelsall BL, Strober W: Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Payer's patch. J Exp Med 1996, 183:237-248.
-
(1996)
J Exp Med
, vol.183
, pp. 237-248
-
-
Kelsall, B.L.1
Strober, W.2
-
44
-
-
0029068495
-
Rat intestinal dendritic cells: Immunostimulatory potency and phenotypic characterization
-
Liu LM, Macpherson GG: Rat intestinal dendritic cells: immunostimulatory potency and phenotypic characterization. Immunol 1995, 85:88-93. This paper demonstrates that dendritic cells derived from the intestine have the potential to stimulate immune reactions.
-
(1995)
Immunol
, vol.85
, pp. 88-93
-
-
Liu, L.M.1
Macpherson, G.G.2
-
45
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, Horak I: Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993, 75:253-261.
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
46
-
-
0027531528
-
Transforming growth factor b1 null mutation in mice causes excessive inflammatory response and early death
-
Kulkarni AB, Huh C, Becherk DD, Geiser A, Lyght M, Flanders KC, Roverts AB, Sporn MB, Ward JM, Karlsson S: Transforming growth factor b1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci U S A 1993, 90:770-774.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 770-774
-
-
Kulkarni, A.B.1
Huh, C.2
Becherk, D.D.3
Geiser, A.4
Lyght, M.5
Flanders, K.C.6
Roverts, A.B.7
Sporn, M.B.8
Ward, J.M.9
Karlsson, S.10
-
47
-
-
0028877061
-
T cells, but not B cells, are required for bowel inflammation in interleukin 2 deficient mice
-
Ma A, Datta M, Margosian E, Chen J, Horak I: T cells, but not B cells, are required for bowel inflammation in interleukin 2 deficient mice. J Exp Med 1995, 182:1567-1572. ce deficient in interleukin-2 develop anemia and colitis. The authors show that spontaneous intestinal disease requires the presence of T cells and that anemia is dependent on B cells.
-
(1995)
J Exp Med
, vol.182
, pp. 1567-1572
-
-
Ma, A.1
Datta, M.2
Margosian, E.3
Chen, J.4
Horak, I.5
-
48
-
-
0029618694
-
Early onset multifocal inflammation in the transforming growth factor β1 null mouse is lymphocyte mediated
-
Diebold RJ, Eis MJ, Yin M, Orbsby I, Boivin GP, Darrow BJ, Saffitz JE. Doetschman T: Early onset multifocal inflammation in the transforming growth factor β1 null mouse is lymphocyte mediated. Proc Natl Acad Sci U S A 1995, 92:12215-12219. A combination of immunosuppressive therapy and cross-breeding of severe combined immunodeficiency mice was used to illustrate that lymphocytes are essential for the manifestation of inflammation in TGF-β1 knockout mice.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 12215-12219
-
-
Diebold, R.J.1
Eis, M.J.2
Yin, M.3
Orbsby, I.4
Boivin, G.P.5
Darrow, B.J.6
Saffitz, J.E.7
Doetschman, T.8
-
51
-
-
0027930912
-
Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line
-
Kaoutzani P, Colgan SP, Cepek KL, Burkard PG, Carlson S, Deep-Archer C Brenner MB, Madara JL: Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. J Clin Invest 1994, 94:788-796.
-
(1994)
J Clin Invest
, vol.94
, pp. 788-796
-
-
Kaoutzani, P.1
Colgan, S.P.2
Cepek, K.L.3
Burkard, P.G.4
Carlson, S.5
Deep-Archer, C.6
Brenner, M.B.7
Madara, J.L.8
-
53
-
-
0029015464
-
1 cells
-
1 cells. Science 1995, 269:245-247.
-
(1995)
Science
, vol.269
, pp. 245-247
-
-
Pernis, A.1
Gupta, S.2
Gollob, K.J.3
Garfein, E.4
Coffman, R.L.5
Schindler, C.6
Rothman, P.7
-
54
-
-
0029671317
-
Regulation of NF-κB activation in T helper 1 and T helper 2 cells
-
Lederer JA, Liou JS, Kim S, Rice N, Lichtman AH: Regulation of NF-κB activation in T helper 1 and T helper 2 cells. J Immunol 1996, 156:56-63.
-
(1996)
J Immunol
, vol.156
, pp. 56-63
-
-
Lederer, J.A.1
Liou, J.S.2
Kim, S.3
Rice, N.4
Lichtman, A.H.5
-
55
-
-
0028879232
-
Immunogenetics of cytokines: Relevance for future research on inflammatory bowel disease
-
Koutroubakis I, Crusius JBA, Pena AS: Immunogenetics of cytokines: relevance for future research on inflammatory bowel disease. Scand J Gastroenterol 1995, 30:1139-1146.
-
(1995)
Scand J Gastroenterol
, vol.30
, pp. 1139-1146
-
-
Koutroubakis, I.1
Crusius, J.B.A.2
Pena, A.S.3
-
56
-
-
0028815553
-
Interleukin 10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance
-
Berg D, Kuhn R, Rajewsky K, Muller W, Menon S, Davidson N, Grunig G: Interleukin 10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J Clin Invest 1995, 96:2339-2347.
-
(1995)
J Clin Invest
, vol.96
, pp. 2339-2347
-
-
Berg, D.1
Kuhn, R.2
Rajewsky, K.3
Muller, W.4
Menon, S.5
Davidson, N.6
Grunig, G.7
-
57
-
-
0029993786
-
Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 of antibodies to interleukin-12
-
Duchmann R, Schmitt E, Knolle P, Zumbuschenfelde KHM, Neurath M: Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 of antibodies to interleukin-12. Eur J Immunol 1996, 26:934-938. Intrarectal instillation of TNBS to Balb/c mice resulted in loss of local and systemic tolerance to bacterial sonicates. Concomitant treatment (intraperitoneal injection) with recombinant IL-10 or antibodies to IL-12 along with TNBS restored tolerance (splenocytes, lymphocytes from small and large intestine) to bacterial sonicates from autologous intestine.
-
(1996)
Eur J Immunol
, vol.26
, pp. 934-938
-
-
Duchmann, R.1
Schmitt, E.2
Knolle, P.3
Zumbuschenfelde, K.H.M.4
Neurath, M.5
-
58
-
-
0029935847
-
Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide-38 inhibit IL-10 production in murine T lymphocytes
-
Martinez C, Delgado M, Gomariz RP, Ganea D: Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide-38 inhibit IL-10 production in murine T lymphocytes. J Immunol 1996, 156:4128-4136.
-
(1996)
J Immunol
, vol.156
, pp. 4128-4136
-
-
Martinez, C.1
Delgado, M.2
Gomariz, R.P.3
Ganea, D.4
-
59
-
-
0029878041
-
Pro-opiomelanocortin derived peptides induce IL-10 production in human monocytes
-
Bhardwaj RS, Schwarz A, Becher E, Mahnke K, Aragane Y, Schwartz T, Luger TA: Pro-opiomelanocortin derived peptides induce IL-10 production in human monocytes. J Immunol 1996, 156:2517-2521.
-
(1996)
J Immunol
, vol.156
, pp. 2517-2521
-
-
Bhardwaj, R.S.1
Schwarz, A.2
Becher, E.3
Mahnke, K.4
Aragane, Y.5
Schwartz, T.6
Luger, T.A.7
-
60
-
-
0028884906
-
Involvement of eicosanoids and macrophage-like cells in cytokine-mediated changes in rat myenteric nerves
-
Ruhl A, Berezin I, Collins SM: Involvement of eicosanoids and macrophage-like cells in cytokine-mediated changes in rat myenteric nerves. Gastroenterology 1995, 109:1852-1862.
-
(1995)
Gastroenterology
, vol.109
, pp. 1852-1862
-
-
Ruhl, A.1
Berezin, I.2
Collins, S.M.3
-
61
-
-
0029130993
-
Implication of NK1 and NK2 receptors in rat colonic hypersecretion induced by interleukin 1β: Role of nitric oxide
-
Eutamene H, Vassilia T, Jean F, Bueno L: Implication of NK1 and NK2 receptors in rat colonic hypersecretion induced by interleukin 1β: role of nitric oxide. Gastroenterology 1995, 109:483-489.
-
(1995)
Gastroenterology
, vol.109
, pp. 483-489
-
-
Eutamene, H.1
Vassilia, T.2
Jean, F.3
Bueno, L.4
-
62
-
-
0029011542
-
Nitric oxide inhibits LPS-induced IL-6 production in enterocytes
-
Meyer TA, Tiao GM, James JH, Noguchi Y, Ogle CK, Fischer JE, Hasseigren PO: Nitric oxide inhibits LPS-induced IL-6 production in enterocytes. J Surg Res 1995, 58:570-575.
-
(1995)
J Surg Res
, vol.58
, pp. 570-575
-
-
Meyer, T.A.1
Tiao, G.M.2
James, J.H.3
Noguchi, Y.4
Ogle, C.K.5
Fischer, J.E.6
Hasseigren, P.O.7
-
63
-
-
0029922844
-
Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion
-
2+ and to cyclic AMP-evoked chloride secretion. This study highlights the importance of the microenvironment in determining epithelial physiology.
-
(1996)
J Biol Chem
, vol.271
, pp. 7460-7464
-
-
Zund, G.1
Madara, J.L.2
Dzus, A.3
Awtrey, C.S.4
Colgan, S.P.5
-
64
-
-
0030068217
-
Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
-
Hilton DJ, Zhang J, Metcalf D, Alexander WS, Nicola NA, Wilson TA: Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci U S A 1996, 93:497-501.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 497-501
-
-
Hilton, D.J.1
Zhang, J.2
Metcalf, D.3
Alexander, W.S.4
Nicola, N.A.5
Wilson, T.A.6
-
65
-
-
0028814039
-
Expression of interleukin 8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro
-
Crowe S, Alvarez L, Dytoc M, Hunt RH, Muller M, Sherman P, Patel J, Jin Y, Ernst PB: Expression of interleukin 8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro. Gastroenterology 1995, 108:65-74.
-
(1995)
Gastroenterology
, vol.108
, pp. 65-74
-
-
Crowe, S.1
Alvarez, L.2
Dytoc, M.3
Hunt, R.H.4
Muller, M.5
Sherman, P.6
Patel, J.7
Jin, Y.8
Ernst, P.B.9
-
66
-
-
0029921168
-
T lymphocyte recruitment by interleukin-8 (IL-8): IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo
-
Taub D, Anver M, Oppenheim J, Longo D, Murphy W: T lymphocyte recruitment by interleukin-8 (IL-8): IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo. J Clin Invest 1996, 97:1931-1941. This paper reports that severe combined immunodeficiency mice reconstituted with T cells and treated with IL-8 initially show neutrophil recruitment (within 4 hours) followed by a later (72-hour) accumulation of T cells at the site of cytokine administration.
-
(1996)
J Clin Invest
, vol.97
, pp. 1931-1941
-
-
Taub, D.1
Anver, M.2
Oppenheim, J.3
Longo, D.4
Murphy, W.5
-
67
-
-
0029963596
-
Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patients
-
Maiuri L, Picarelli A, Boirivant M, Coletta S, Mazzilli MC, Devincenzi M, Londei M, Auricchio S: Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patients. Gastroenterology 1996, 110:1368-1378. This paper highlights the putative role of the intestinal epithelium in celiac disease, a condition generally considered a T-cell disorder. Data are presented showing that increased major histocompatibility class II expression on the epithelium precedes full T-cell activation in response to gliadin.
-
(1996)
Gastroenterology
, vol.110
, pp. 1368-1378
-
-
Maiuri, L.1
Picarelli, A.2
Boirivant, M.3
Coletta, S.4
Mazzilli, M.C.5
Devincenzi, M.6
Londei, M.7
Auricchio, S.8
-
68
-
-
0028877712
-
Nerve growth factor synthesis by intestinal epithelial cells
-
Varilek GW, Neil GA, Bishop WP, Lin J, Pantazis NJ: Nerve growth factor synthesis by intestinal epithelial cells. Am J Physiol 1995, 269:G445-G452.
-
(1995)
Am J Physiol
, vol.269
-
-
Varilek, G.W.1
Neil, G.A.2
Bishop, W.P.3
Lin, J.4
Pantazis, N.J.5
-
69
-
-
0026332943
-
Remodelling of B-50 (GAP-43)- And NSE-immunoreactive mucosal nerves in the intestines of rats infected with Nippostrongylus brasiliensis
-
Stead RH, Kosecka-Janiszewska U, Oestreicher AB, Dixon MF, Bienenstock J: Remodelling of B-50 (GAP-43)- and NSE-immunoreactive mucosal nerves in the intestines of rats infected with Nippostrongylus brasiliensis. J Neurosci 1991, 11:3809-3821.
-
(1991)
J Neurosci
, vol.11
, pp. 3809-3821
-
-
Stead, R.H.1
Kosecka-Janiszewska, U.2
Oestreicher, A.B.3
Dixon, M.F.4
Bienenstock, J.5
-
70
-
-
0029914865
-
Activation of T lymphocytes by syngeneic murine intestinal smooth muscle cells
-
Hogaboam CM, Snider DP, Collins SM: Activation of T lymphocytes by syngeneic murine intestinal smooth muscle cells. Gastroenterology 1996, 110:1456-1466.
-
(1996)
Gastroenterology
, vol.110
, pp. 1456-1466
-
-
Hogaboam, C.M.1
Snider, D.P.2
Collins, S.M.3
-
71
-
-
0029050742
-
Treatment of Crohn's disease with anti tumor necrosis factor chimeric monoclonal antibody (cA2)
-
Van Dullemen H, Van Deventer S, Hommes DW, Bijl H, Jansen J, Tytgat GNJ, Woody J: Treatment of Crohn's disease with anti tumor necrosis factor chimeric monoclonal antibody (cA2). Gastroenterology 1995, 109:129-135
-
(1995)
Gastroenterology
, vol.109
, pp. 129-135
-
-
Van Dullemen, H.1
Van Deventer, S.2
Hommes, D.W.3
Bijl, H.4
Jansen, J.5
Tytgat, G.N.J.6
Woody, J.7
-
72
-
-
0029112434
-
Anti-inflammatory effects of CGP 47969A, a novel inhibitor of proinflammatory cytokine synthesis, in rabbit immune colitis
-
Casini-Raggi V, Monsacchi L, Vosbeck K, Nast C, Pizarro T, Cominelli F: Anti-inflammatory effects of CGP 47969A, a novel inhibitor of proinflammatory cytokine synthesis, in rabbit immune colitis. Gastroenterology 1995, 109:812-815.
-
(1995)
Gastroenterology
, vol.109
, pp. 812-815
-
-
Casini-Raggi, V.1
Monsacchi, L.2
Vosbeck, K.3
Nast, C.4
Pizarro, T.5
Cominelli, F.6
-
73
-
-
0029100370
-
A nitric oxide releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats
-
Elliott SN, McKnight W, Cirino G, Wallace JL: A nitric oxide releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats. Gastroenterology 1995, 109:524-530.
-
(1995)
Gastroenterology
, vol.109
, pp. 524-530
-
-
Elliott, S.N.1
McKnight, W.2
Cirino, G.3
Wallace, J.L.4
-
74
-
-
0029020655
-
Colonic delivery of dexamethasone from a prodrug accelerates healing of colitis in rats without adrenal suppression
-
Fedorak R, Haeberlin B, Empey LR, Cui N, Nollen H III, Jewell LD, Friend DR: Colonic delivery of dexamethasone from a prodrug accelerates healing of colitis in rats without adrenal suppression. Gastroenterology 1995, 108:1688-1699. Compared with dexamethasone, an orally delivered dexamethasone-β-D-glucuronide conjugate is more potent in improving colonic water absorption and reducing the area of ulceration and histologic scope in rats treated with 4% acetic acid. The prodrug also maintains the levels of adrenocorticotropic hormone and corticosterone at close to normal.
-
(1995)
Gastroenterology
, vol.108
, pp. 1688-1699
-
-
Fedorak, R.1
Haeberlin, B.2
Empey, L.R.3
Cui, N.4
Nollen III, H.5
Jewell, L.D.6
Friend, D.R.7
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