Heterologous Expression of α1-Integrin cDNA Generates Variable Ligand Specificities and Alterations in Cell Shape

Cell Communication and Adhesion

Volumn 4, Issue 3, 1996, Pages 201-221

  Wong, Lianna D ^a   Sondheim, Anne B ^b   Zachow, Karen R ^a   Reichardt, Louis F ^b   Ignatius, Michael J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell Adhesion; Extracellular Matrix; Laminin. Collagen; Megakaryocyte Differentiation

Indexed keywords

COMPLEMENTARY DNA; INTEGRIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL SHAPE; CELL SPREADING; CELL STRAIN K 562; HUMAN; HUMAN CELL; LIGAND BINDING; MEGAKARYOCYTE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIGENS, CD; CELL ADHESION; CELL ADHESION MOLECULES; CELL SIZE; CELLS, CULTURED; COLLAGEN; DNA, COMPLEMENTARY; FIBRONECTINS; HUMANS; INTEGRIN ALPHA1; LIGANDS; RATS; TRANSFECTION;

ANIMALIA;

EID: 0029849104     PISSN: 15419061     EISSN: 15435180     Source Type: Journal    
DOI: 10.3109/15419069609014223     Document Type: Article

References (64)

1. Albelda S. M., Buck C. A. Integrins and other cell ad hesion molecules. Faseb J 1990; 4: 2868 – 2880
2. Anderson L. C., Jokinen M., Gahmberg C. G. Induc tion of erythroid differentiation in the human leukemia cell line K562. Nature 1979; 278: 364 – 365
3. Andrew D. P., Berlin Honda C. S., Yoshino T., Hamann A., Holzmann B., Kilshaw P. J., Butcher E. C. Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1. mucosal addressin-1, fibronectin, and lymphocyte aggregation. J. Immunol. 1994; 153: 3847 – 3861
4. Arroyo A. G., Sanchez-Mateos P., Campanero M. R., Martin-Padura I., Dejana E., Sanchez-Madrid F. Regulation of the VLA integrin-ligand interactions through the beta 1 subunit. J. Cell Biol. 1992; 117: 659 – 670
5. Bazzoni G., Shih D T., Buck C. A., Hemler M. E. Monoclonal antibody 9EG7 defines a novel beta 1 imegrin epitope induced by soluble ligand and managanese. but inhibited by calcium. J. Biol. Chem. 1995; 270: 25570 – 25577
6. Belkin V. M., Belkin A. M., Koteliansky V. E. Human smooth muscle VLA-1 integrin: purification, substrate specific ity, localization in aorta, and expression during development. J. Cell Biol. 1990; 111: 2159 – 2170
7. Bodary S. C., McLean J. W. The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. J. Biol. Chem. 1990; 265.: 5938 – 5941
8. Burger S. R., Zutter M. M., Sturgill-Koszycki S., Santoro S. A. Induced cell surface expression of functional α2β1 integrin during megakaryocutic differentiation of k562 leukemic cells. Exper. Cell Res. 1992; 202: 28 – 35
9. Butler T. M., Ziemiecki A., Friis R. R. Megakaryocytic differentiation of K562 cells is associated with changes in the cytoskeletal organization and the pattern of chromatographically distinct forms of phosphotyrosyl-specific protein phosphatases. Cancer Res. 1990; 50: 6323 – 6329
10. Chammas R., Veiga S. S., Travassos L. R., Brentani R. R. Functionally distinct roles for glycosylation of alpha and beta integrin chains in cell-matrix interactions. Proc. Natl. Acad. Sci. USA 1993; 90: 1795 – 1799
11. Chan B. M., Matsuura N., Takada Y., Zetter B. R., Hemler M. E. In vitro and in vivo consequences of VLA-2 ex pression on rhabdomyosarcoma cells. Science 1991; 251: 1600 – 1602
12. Chan B. M., Hemler M. E. Multiple functional forms of the integrin VLA-2 can be derived from a single α2 cDNA clone: Interconversion of forms induced by an anti-β1 antibody. J. Cell Biol. 1993; 120.: 537 – 543
13. Cheresh D. A., Pierschbacher M. D., Herzig M. A., Mujoo K. Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to ex tracellular matrix proteins. J. Cell Biol. 1986; 102.: 688 – 696
14. Cheresh D. A., Pytela R., Pierschbacher M. D., Klier F. G., Ruoslahti E., Reisfeld R. A. An arg-gly-asp-directed re ceptor on the surface of human melanoma cells exists in a diva lent cation-dependent functional complex with a disialoganglioside GD2. J. Cell Biol. 1987; 105.: 1163 – 1173
15. Conforti G., Zanetti A., Pasquali-Ronchetti I., Quaglino D., Jr, Neyroz P., Dejana E. Modulation of vitronectin re ceptor binding by membrane lipid composition. J. Biol. Chem. 1990; 265: 4011 – 4019
16. Dahl S. C., Grabel L. B. Integrin phosphorylation is modulated during the differentiation of F-9 teratocarcinoma stem cells. J. Cell Biol. 1989; 108: 183 – 190
17. Defilippi P., van Hinsbergh V., Bertolotto A., Rossino P., Silengo L., Tarone G. Differential distribution and modulation of expression of alpha 1/betal integrin on human endothelial cells. J. Cell Biol. 1991; 114: 855 – 863
18. Delwel G. O., Hogervorst F. F., Kuikman I., Paulsson M., Timpl R., Sonnenberg A. Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interac tion with isoforms of laminin. J. Biol. Chem. 1993; 268: 25865 – 25875
19. Doherty P., Ashton S. V., Skaper S. D., Leon A., Walsh F. S. Ganglioside modulation of neural cell adhesion molecule and N-cadherin-dependent neurite outgrowth. J. Cell Biol. 1992; 117: 1093 – 1099
20. Elices M. J., Hemler M E. The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc. Natl. Acad. Sci. USA 1989; 86: 9906 – 9910
21. Forsberg E., Paulsson M., Timpl R., Johansson S. Characterization of a laminin receptor on rat hepatocytes. J. Biol. Chem. 1990; 265: 6376 – 6381
22. Gullberg D., Turner D. C., Borg T. K., Terracio L., Rubin K. Different β1-integrin collagen receptors on rat hepato cytes and cardiac fibroblasts. Exp. Cell Res. 1990; 190: 254 – 264
23. Gunning P., Leavitt J., Muscat G., Ng S. Y., Kedes L. A human β-actin expression vector system directs high-level accumulation of antisense transcripts. Proc. Natl. Acad. Sci. USA 1987; 84: 4831 – 4835
24. Haas T. A., Plow E. F. Integrin-ligand interactions: a year in review. Curr. Op. Cell Biol. 1994; 6: 656 – 662
25. Hemler M. E. Adhesive protein receptors on hematopoietc cells. Immunol. Today 1988; 9: 109 – 113
26. Hynes R. O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11 – 25
27. Ignatius M. J., Reichardt L. F. Identification of a neuronal laminin receptor: an Mr 200K/120K integrin heterodimer that binds laminin in a divalent cation-dependent manner. Neuron 1988; 1: 713 – 725
28. Ignatius M. J., Large T. H., Houde M., Tawil J. W., Barton A., Esch F., Carbonetto S., Reichardt L. F. Molecular cloning of the rat integrin alpha 1-subunit: a receptor for laminin and collagen. J. Cell Biol. 1990; 111: 709 – 720
29. Lida J., Skubitz A. P., Furcht L. T., Wayner E. A., McCarthy J. B. Coordinate role for cell surface chondroitin sulfate proteoglycan and alpha 4 beta 1 integrin in mediating melanoma cell adhesion to fibronectin. J. Cell Biol. 1992; 118: 431 – 44
30. Jarvinen M., Ylanne J., Virtanen I. () The effect of differentiation inducers on the integrin expression of K562 erythroleukemia cells. Cell Biol. Intern. 1993; 17: 399 – 407
31. Kamata T., Takada Y. Direct binding of collagen to the I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29) in a divalent cation-independent manner. J. Biol. Chem. 1994; 269: 26006 – 260010
32. Kern A., Briesewitz R., Bank I., Marcantonio E. E. The role of the I domain in ligand binding of the human integrin alpha 1 beta 1. J. Biol. Chem. 1994; 269: 22811 – 22816
33. Kirchhofer D., Languino L. R., Ruoslahti E., Pierschbacher M. D. Alpha 2 beta 1 tntegrins from different cell types show different binding specificities. J. Biol. Chem. 1987; 265: 615 – 618
34. Lampe B. V., Stallmach A., Riecken E. O. Altered glycosylation of integrin adhesion molecules in colorectal cancer cells and decreased adhesion to the extracellular matrix. Gut 1993; 34: 829 – 836
35. Lein P. J., Higgins D., Turner D. C., Flier L. A., Terranova V. P. The NCI domain of type IV collagen promotes axonal growth in sympathetic neurons through interaction with the alpha 1 beta 1 integrin. J. Cell Biol. 1991; 113: 417 – 428
36. Lozzio B. B., Lozzio C. B. Properties and usefullness of the original K-562 human myelogenous leukemia cell line. Leukemia Res. 1979; 3: 363 – 370
37. Masumoto A., Hemler M. E. Mutation of putative diva lent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin. J. Cell Biol. 1993; 123: 245 – 53
38. Moss L., Prakobphol A., Wiedmann T. W., Fisher S. J., Damsky C. H. Glycosylation of human trophoblast integrins is stage and cell-type specific. Glycobiology 1994; 4: 567 – 575
39. Neugebauer K. N., Reichardt L. F. Cell-surface regula tion of β1-integrin activity on developing neurons. Nature 1991; 350: 68 – 71
40. Perris R., Bronner-Fraser M. Recent advances in de fining the role of the extracellular matrix in neural crest devel opment. Comm. on Dev. Neurobiol. 1989; 1: 61 – 83
41. Pulido R., Elices M. J., Campanero M. R., Osborn L., Schiffer S., Garcia-Pardo A., Lobb R., Hemler M. E., Sanchez-Madrid F. Functional evidence for three distinct and indepen dently inhibitable adhesion activities mediated by the human integrin VLA-4. J. Biol. Chem. 1991; 266: 10241 – 10245
42. Pullman W. E., Bodmer W. F. Cloning and character ization of a gene that regulates cell adhesion. Nature 1992; 356: 529 – 532
43. Reh T. A., Nagy T., Gretton H. Retinal pigmented epithelial cells induced to transdifferentiate to neurons by lami nin. Nature 1987; 330: 68 – 71
44. Reichardt L. F., Tomaselli K. J. Extracellular matrix molecules and their receptors: functions in neural development. Annu. Rev. Neurosci. 1991; 14: 531 – 70
45. Santala P., Heino J. Regulation of integrin-type cell adhesion by cytokines. J. Biol. Chem. 1991; 266: 23505 – 23509
46. Schwartz M. A. Transmembrane signalling by integrins. Trends Cell Biol. 1992; 2: 304 – 308
47. Sutherland J. A., Turner A. R., Mannoni P., McGann L. E., Turc J. M. Differentiation of K562 leukemia cells. J. Biol. Resp. Modif. 1986; 5: 250 – 262
48. Symington B. E., Symington F. W., Rohrschneider L. R. Phorbol ester induces increased expression, altered glycosylation, and reduced adhesion of K562 erythroleukemia cell fibronectin receptors. J. Biol. Chem. 1989; 264: 13258 – 13266
49. Symington B. E. Fibronectin receptor overexpression and loss of transformed phenotype in a stable variant of the K562 cell line. Cell Regulation 1990; 1: 637 – 648
50. Tablin F, Castro M., Leven R. M. Blood platelet for mation in vitro. The role of the cytoskeleton in megakaryocyte fragmentation. J. Cell Sci. 1990; 97: 59 – 70
51. Takada Y., Puzon W. Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies. J. Biol Chem. 1993; 268: 17597 – 17601
52. Tamura R. N., Rozzo C., Starr L., Chambers Reichardt J., Cooper L. F.H.M., Quaranta V. Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4. J. Cell Biol 1990; 111: 1593 – 604
53. Tarentino A. L., Gomez C. M., Plummer T. H., Jr. Deglycosylation of asparagine-linked glycans by peptide: N-glycosidase F. Biochem. 1985; 24: 4665 – 4671
54. Tawil N. J., Houde Blacher M. R., Esch F., Reichardt L. F., Turner D. C., Carbonetto S. Alpha 1 beta 1 integrin heterodiraer functions as a dual laminin/collagen receptor in neural cells. Biochem. 1990; 29: 6540 – 6544
55. Timpl R., Rohde H., Ristidi L., Ott U., Robey P. G., Martin G. R. Laminin. Meth. Enzymol. 1982; 82: 831 – 838
56. Topp K. S., Tablin F., Levin J. Culture of isolated bovine megakaryocytes on reconstituted basement membrane matrix leads to proplatelet process formation. Blood 1990; 76: 912 – 24
57. Trimble R. B., Maley F. Optimizing hydrolysis of Nlinked high-mannose oligosaccharides by endo-β-N-acetglu-cosaminidase H. Anal. Biochem. 1984; 141: 512 – 522
58. Tuckwell D., Calderwood D. A., Green L. J., Humphries M. J. Integrin α2 1-domain is a binding site for collagens. J. Cell Sci. 1995; 108: 1629 – 1637
59. Turner D. O., Flier L. A., Carbonetto S. Identification of a cell-surface protein involved in PC 12 cell-substratum adhe sion and neurite outgrowth on laminin and collagen. J. Neurosci. 1989; 9: 3287 – 3296
60. Veiga S. S., Chammas R., Cella N., Brentani R. R. Glycosylation of beta-1 integrins in B16-F10 mouse melanoma cells as determinant of differential binding and acquisition of biological activity. Int. J. Cancer 1995; 61: 420 – 424
61. Wadsworth S., Halvorson M. J., Chang A. C., Coligan J. E. Multiple changes in VLA protein glycosylation, expres sion, and function occur during mouse T cell ontogeny. J. Immunol. 1993; 150: 847 – 857
62. Wayner E. A., Carter W. G., Piotrowicz R. S., Kunicki T. J. The function of multiple ECM receptors in mediating cell adhesion to ECM. J. Cell Biol. 1988; 107: 1881 – 1891
63. Zheng M., Fang H., Hakomori S. Functional role of N-glycosylation in α5β1 integrin receptor. J. Biol. Chem. 1994; 269: 12325 – 12331
64. Zutter M. M., Fong A. M., Krigman H. R., Santoro S. A. Differential regulation of the α2β1 and αIIbβ3 integrin genes during megakaryocytic differentiation of pluripotential K562 cells. J. Biol. Chem. 1992; 267: 20233 – 20238