Influence of mitochondrial protein synthesis inhibition on deafferentation-induced ultrastructural changes in nucleus magnocellularis of developing chicks

Journal of Comparative Neurology

Volumn 371, Issue 3, 1996, Pages 448-460

  Hartlage Rübsamen, Maike ^a   Rubel, Edwin W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

deafferentation; n. magnocellularis; neuronal death; protein synthesis; ribosomes

Indexed keywords

ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL ULTRASTRUCTURE; CHICK EMBRYO; COCHLEA; CONTROLLED STUDY; DEAFFERENTATION; MAGNOCELLULAR NUCLEUS; MITOCHONDRIAL RESPIRATION; NERVE CELL NECROSIS; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; ROUGH ENDOPLASMIC RETICULUM;

AFFERENT PATHWAYS; ANIMALS; ANIMALS, NEWBORN; CELL SURVIVAL; CHICKENS; CHLORAMPHENICOL; COCHLEA; CYTOPLASM; DENERVATION; EVALUATION STUDIES; MITOCHONDRIA; NERVE TISSUE PROTEINS; POLYRIBOSOMES; PROTEIN SYNTHESIS INHIBITORS; SUBSTANTIA INNOMINATA;

EID: 0029847001     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19960729)371:3<448::AID-CNE7>3.0.CO;2-2     Document Type: Article

References (81)

1. Agardh, C.D., J. Folbergrová, and B. Siesjö (1978) Cerebral metabolic changes in profound, insulin-induced hypoglycemia, and in the recovery period following glucose administration. J. Neurochem. 31:1135-1142.
2. Alberts, B., D. Bray, J. Lewis, M. Raff, K. Roberts, and J.D. Watson (1989) Molecular biology of the cell. New York: Garland Publishing, pp. 342-366.
3. Attardi, G. and G. Schatz (1988) Biogenesis of mitochondria. Ann. Rev. Cell Biol. 4:289-333.
4. Bergstedt, K., B.R. Hu, and T. Wieloch (1993) Initiation of protein synthesis and heat-shock protein-72 expression in the rat brain following severe insulin-induced hypoglycemia. Acta Neuropathol. 86:145-153.
5. Boobis, A.R., D.J. Fawthrop, and D.S. Davies (1989) Mechanisms of cell death. TiPS 10:275-280.
6. Born, D.E. and E.W Rubel (1985) Afferent influences on brainstem auditory nuclei of the chicken: Neuron number and size following cochlea removal. J. Comp. Neurol. 231:435-445.
7. Born, D.E. and E.W Rubel (1988) Afferent influences on brainstem auditory nuclei of the chicken: Presynaptic action potentials regulate protein synthesis in nucleus magnocellularis. J. Neurosci. 8:901-919.
8. Born, D.E., D. Durham, and E.W Rubel (1991) Afferent influences on brainstem auditory nuclei of the chicken: Neuron number and size following cochlea removal. Brain Res. 557:37-47.
9. Brand, M.D. and M.P. Murphy (1987) Control of electron flux through the respiratory chain in mitochondria and cells. Biol. Rev. Camb. Phil. Soc. 62:141-193.
10. Cheung, J.Y., J.V. Bonventre, C.D. Malis, and A. Leaf (1986) Calcium and ischemic injury. N. Engl. J. Med. 314:1670-1676.
11. Choi, D.W. (1987) Ionic dependence of glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:369-379.
12. Choi, D.W. (1988a) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1:623-634.
13. Choi, D.W. (1988b) Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage. TINS 11:465-469
14. Clarke, P.G.H. (1990) Developmental cell death: morphological diversity and multiple mechanisms. Anat. Embryol. 181:195-213.
15. 2+ as a second messenger within mitochondria of the heart and other tissues. Annu. Rev. Physiol. 52:451-466.
16. Durham, D. and E.W Rubel (1985) Afferent influences on brain stem auditory nuclei of the chicken: Changes in succinate dehydrogenase activity following cochlea removal. J. Comp. Neurol. 231:446-456.
17. Durham, D., F.M. Matschinsky, and E.W Rubel (1993) Altered malate dehydrogenase activity in nucleus magnocellularis of the chicken following cochlea removal. Hear. Res. 70:151-159.
18. Fein, A. and M. Tsacopoulos (1988) Activation of mitochondrial oxidative metabolism by calcium ions in Limulus ventral photoreceptor. Nature 331:437-440.
19. Furber, S., R.W. Oppenheim, and D. Prevette (1987) Naturally-occurring neuron death in the ciliary ganglion of the chick embryo following removal of preganglionic input: Evidence for the role of afferents in ganglion cell survival. J. Neurosci. 7:1816-1832.
20. Garden, G.A., K.S. Canady, D.I. Lurie, M. Bothwell, and E.W Rubel (1994) A biphasic change in ribosomal conformation during transneuronal degeneration is altered by inhibition of mitochondrial, but not cytoplasmic protein synthesis. J. Neurosci. 14:1994-2008.
21. Garden, G.A., V. Redeker-DeWulf, and E.W Rubel (1995a) Changes in transcriptional activity of chicken auditory brainstem neurons following loss of afferent innervation. J. Comp. Neurol. 359:412-423.
22. Garden, G.A., M. Hartlage-Rübsamen, E.W Rubel, and M. Bothwell (1995b) Protein masking of a ribosomal RNA epitope is an early event in afferent deprivation induced neuronal death. Molec. Cell. Neurosci. 6:293-310.
23. Hallmann, M. (1973) Oxygen uptake in neonatal rats: a developmental study with particular reference to the effects of chloramphenicol. Paediatr. Res. 7:923-930.
24. 2+ loads from rat adrenal chromatin cells. Neuron. 16:119-228.
25. Hershey, J.W.B. (1990) Overview: Phosphorylation and translation control. Enzyme 44:17-27.
26. Hockenbery, D.M., Z.N. Oltvai, X.M. Yin, C.L. Milliman, and S.J. Korsmeyer (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251.
27. Holt, D., D. Harvey, and R. Hurley (1993) Chloramphenicol toxicity. Adverse Drug React. Toxicol. Rev. 12:83-95.
28. Hossmann, K.A. and P. Kleihues (1973) Reversibility of ischemic brain damage. Arch. Neurol. 29:375-382.
29. Houge, G., S.O. Døskeland, R. Bøe, and M. Lanotte (1993) Selective cleavage of 28S rRNA variable regions V3 and V13 in myeloid leukemia cell apoptosis. FEBS Letters 315:16-20.
30. Hyde, G.E. and D. Durham (1990) Cytochrome oxidase response to cochlea removal in chicken auditory brainstem neurons. J. Comp. Neurol. 297:329-339.
31. Hyde, G.E. and D. Durham (1994a) Rapid increase in mitochondrial volume in nucleus magnocellularis neurons following cochlea removal. J. Comp. Neurol. 339:27-48.
32. Hyde, G.E. and D. Durham (1994b) Increased deafferentation-induced cell death in chick brainstem auditory neurons following blockade of mitochondrial protein synthesis with chloramphenicol. J. Neurosci. 14:291-300.
33. Jagus, R., W. French Anderson, and B. Safer (1981) The regulation of initiation of mammalian protein synthesis. In: Progress in Nucleic Acid Research and Molecular Biology, 25:129-185. New York: Academic Press.
34. Jhaveri, S. and D.K. Morest (1982a) Neuronal architecture in nucleus magnocellularis of the chick auditory system with observations on nucleus laminaris: A light and electron microscope study. Neurosci. 7:809-836.
35. Jhaveri, S. and D.K. Morest (1982b) Sequential alterations of neuronal architecture in nucleus magnocellularis of the developing chicken: An electron microscope study. Neurosci. 7:855-870.
36. Jiménez, A. (1976) Inhibitors of translation. Trends Biochem. Sci. 1:28-30.
37. Jones, D.A. and H. McIlwain (1971) Amino acid distribution and incorporation into proteins in isolated, electrically-stimulated cerebral tissues. J. Neurochem. 18:41-58.
38. Kane, D.J., T.A. Sarafian, R. Anton, H. Hahn, E.B. Gralla, J.S. Valentine, T. Örd, and D.E. Bredesen (1993) Bcl-2 inhibition of neuronal cell death: Decreased generation of reactive oxygen species. Science 262:1274-1277.
39. 3H] tyrosine incorporation into rat brain proteins during severe hypoglycemia. J. Cereb. Blood Flow Metab. 2:249-253.
40. Kleihues, P. and K.A. Hossmann (1971) Protein synthesis in the cat brain after prolonged cerebral ischemia. Brain Res. 35:409-418.
41. Krause, G.S. and B.R. Tiffany (1993) Suppression of protein synthesis in the reperfused brain. Stroke 24:747-756.
42. Lamb, A.J., G.D. Clark-Walker, and A.W. Linnane (1968) The biogenesis of mitochondria: The differentiation of mitochondrial and cytoplasmic protein synthesizing systems in vitro by antibiotics. Biochem. Biophys. Acta 161:415-427.
43. 2+ ion transport. Biochem. J. 119:129-138.
44. Lipton, P. (1987) Measurement of protein synthesis in hippocampal slices: In vitro versus in vivo. In A. Schurr, T.J. Teyler, and M.T. Tseng (eds): Brain Slices: Fundamentals, Applications and Implications. Switzerland: Karger.
45. 2+ and NMDA receptors. In G. Somjen (ed): Mechanisms of Cerebral Hypoxia and Stroke. New York: Plenum Press, pp. 229-249.
46. Mattson, M.P., Y. Zhang, and S. Bose (1993) Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose. Exp. Neurol. 121:1-13.
47. 2+ concentration. Arch. Biochem. Biophys. 269:365-370.
48. Merrick, W.C. (1990) Overview: Mechanism of translation initiation in eukaryotes. Enzyme 44:7-16.
49. Montisano, D.F. and T.W. James (1979) Mitochondrial morphology in yeast with and without mitochondrial DNA. J. Ultrastruct. Res. 67:288-296.
50. Moore, M.N. and L.L. Spremulli (1985) Effects of cations and cosolvents on eukaryotic ribosomal subunit conformation. Biochemistry 24:191-196.
51. Morley, S.J. and G. Thomas (1991) Intracellular messengers and the control of protein synthesis. Pharmac. Ther. 50:291-319.
52. Murray T., K.M. Dowey, and A.A. Yunis (1982) Degradation of isolated DNA mediated by nitroso-chloramphenicol: Possible role in chloramphenicol-induced aplastic anaemia. Biochem. Pharmacol. 31:2291-2296.
53. O'Connor, T.M. and C.R. Wyttenbach (1974) Cell death in the embryonic chick spinal cord. J. Cell Biol. 60:448-459.
54. Oppenheim, R.W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:453-501.
55. 2+ in toxic cell killing. TiPS 10:281-285.
56. 2+ - dependent mechanisms of cytotoxicity and programmed cell death. Toxicol. Lett. 64/65:357-364.
57. Panniers, R. and E. Henshaw (1983) A GDP/GTP exchange factor essential for recycling in Erlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylation. J. Biol. Chem. 258:7928-7934.
58. Parks, T.N. (1981) Morphology of axosomatic endings in an avian cochlear nucleus: Nucleus magnocellularis of the chicken. J. Comp. Neurol. 203:425-440.
59. Pilar, G. and L. Landmesser (1976) Ultrastructural differences during embryonic death in normal and peripherally deprived ciliary ganglia. J. Cell Biol. 68:339-356.
60. 2+ sequestering pools and the action of inositol 1,4,5-triphosphate. J. Biol. Chem. 259:13777-13782.
61. Raley-Susman, K.M. and P. Lipton (1990) In vitro ischemia and protein synthesis in the rat hippocampal slice: The role of calcium and NMDA receptor activation. Brain Res. 515:27-38.
62. Randall, R.D. and S.A. Thayer (1992) Glutamate-induced calcium transient triggers delayed Calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12:1882-1895.
63. Rhoads, R.E. (1993) Regulation of eukaryotic protein synthesis by initiation factors. J. Biol. Chem. 268:3017-3020.
64. 2+ homeostasis, cell death, proliferation, and differentiation. Chem. Biol. Interactions 77:1-23.
65. Rubel, E.W, R.L. Hyson, and D. Durham (1990) Afferent regulation of neurons in the brain stem auditory system. J. Neurobiol. 21:169-196.
66. Rubel, E.W, P.M. Falk, K.S. Canady, and O. Steward (1991) A cellular mechanism underlying activity-dependent transneuronal degeneration: Rapid but reversible destruction of neuronal ribosomes. Brain Dysfunct. 4:55-74.
67. Sarre, T.F. (1989) The phosphorylation of eukaryotic initiation factor 2: A principle of translational control in mammalian cells. Biosystems 22:311-325.
68. Siesjö, B.K. (1988) Calcium, ischemia and death of brain cells. Ann. NY Acad. Sci. 522:638-661.
69. Simon, R.P., T. Griffith, M.C. Evans, J.H. Swan, and B.S. Meldrum (1984) Calcium overload in selectively vulnerable neurons of the hippocampus during and after ischemia: An electron microscope study in the rat. J. Cereb. Blood Flow Metabol. 4:350-361.
70. Steitz, J.A. (1989) Immunoprecipitation of ribonucleoproteins using autoantibodies. Methods in Enzymol. 180:468-481.
71. Steward, O. and E.W Rubel (1985) Afferent influences on brain stem auditory nuclei of the chicken: Cessation of amino acid incorporation as an antecedent to age-dependent transneuronal degeneration. J. Comp. Neurol. 231:385-395.
72. Tocher, J.H., R.C. Knight, and D.I. Edwards (1988) Electrochemical characteristics of nitro-heterocyclic compounds of biological interest: II. Nitrosochloramphenicol. Free Radical Res. Commun. 5:319-326.
73. 2+ in cell injury, necrosis and apoptosis. Curr. Opinion Cell Biol. 4:227-232.
74. Tzagoloff, A. (1982) Mitochondria. New York:Plenum.
75. Tzagoloff, A. and A.M. Myers (1986) Genetics of mitochondrial biogenesis. Ann Rev Biochem. 55:249-285.
76. Vornov, J.J. and J.T. Coyle (1991) Glutamate neurotoxicity and the inhibition of protein synthesis in the hippocampal slice. J. Neurochem. 56:996-1006.
77. Werth, J.L. and S.A. Thayer (1994) Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons. J. Neurosci. 14:348-356.
78. 14C]Leucine incorporation into brain proteins in gerbils after transient ischemia: Relationship to selective vulnerability of hippocampus. J. Neurochem. 56:789-796.
79. Yunis, A.A. (1988) Chloramphenicol: Relation of structure to activity and toxicity. Annu. Rev. Pharmacol. Toxicol. 28:83-100.
80. Zirpel, L., E.A. Lachica, and W.R. Lippe (1995) Deafferentation increases the intracellular calcium of cochlear nucleus neurons in the embryonic chick. J. Neurophysiol. 74:1355-1357.
81. Zirpel, L. and E.W Rubel (1996) Eighth nerve activity regulates intracellular calcium concentration of avian cochlear nucleus neurons via a metabotropic glutamate receptor. J. Neurophysiol. (in press).