Intention-to-treat analyses for incomplete repeated measures data

Biometrics

Volumn 52, Issue 3, 1996, Pages 1002-1017

  Hogan, Joseph W ^a   Laird, Nan M ^b  

^a BROWN UNIVERSITY   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Dropout; Explanatory analysis; Pediatric AIDS; Pragmatic analysis; Randomized clinical trial

Indexed keywords

DISEASES; MEDICAL APPLICATIONS; PEDIATRICS; PIECEWISE LINEAR TECHNIQUES; RANDOM PROCESSES;

CLINICAL TRIAL; DROPOUT; EXPLANATORY ANALYSE; MEASURE DATA; PAEDIATRIC AIDS; PIECEWISE LINEAR; PIECEWISE-LINEAR; PRAGMATIC ANALYSE; RANDOMIZED CLINICAL TRIALS; REPEATED MEASURES;

MAXIMUM LIKELIHOOD ESTIMATION;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; MULTIVARIATE ANALYSIS; RANDOMIZATION; STATISTICAL ANALYSIS; STATISTICS; SURVIVAL;

EID: 0029846947     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.2307/2533061     Document Type: Article

References (30)

1. AIDS Clinical Trials Group. (1993). A randomized blinded trial to evaluate the safety and tolerance of high versus low dose zidovudine administered to children with human immunodeficiency virus. Protocol 128, Version 6.0 (final). Washington, D.C.: National Institute of Allergy and Infectious Diseases.
2. Armitage, P. (1983). Exclusions, losses to follow-up, and withdrawals in clinical trials. In Clinical Trials, S. H. Shapiro and T. A. Louis (eds), 99-113. New York: Marcel Dekker, Inc.
3. Bayley, N. (1969). Manual for the Bayley Scales of Infant Development. Cleveland: The Psychological Corporation.
4. Brady, M. T., McGrath, N., Brouwers, P., et al. (1996). Randomized study of the tolerance and efficacy of high versus low dose zidovudine in HIV-infected children with mild to moderate symptoms. Journal of Infectious Diseases, in press.
5. Coronary Drug Project Research Group. (1980). Influence of adherence to treatment and response of cholesterol on mortality in the Coronary Drug Project. New England Journal of Medicine 303, 1038-1041.
6. DeGruttola, V. and Tu, X. M. (1995). Modeling progression of CD4-lymphocyte count and its relationship to survival time. Biometrics 50, 1003-1014.
7. Diggle, P. and Kenward, M. G. (1994). Informative drop-out in longitudinal data analysis. Applied Statistics 43, 49-93.
8. Efron, B. and Tibshirani, R. (1986). Bootstrap methods for standard errors, confidence intervals, and other measures of statistical accuracy. Statistical Science 1, 54-77.
9. Fisher, L. D., Dixon, D. O., Herson, J., Frankowski, R. K., Hearron, M. S., and Peace, K. E. (1990). Intention to treat in clinical trials. In Statistical Issues in Drug Research and Development, K. E. Peace (ed), 331-350. New York: Marcel Dekker.
10. Fleming, T. R. and Harrington, D. P. (1991). Counting Processes and Survival Analysis. New York: John Wiley and Sons.
11. Heyting, A., Tolboom, J. T. B. M., and Essers, J. G. A. (1992). Statistical handling of drop-outs in longitudinal clinical trials. Statistics in Medicine 11, 2043-2061.
12. Hogan, J. W. and Laird, N. M. (1996). Mixture models for the joint distribution of repeated measures and event times. Statistics in Medicine, in press.
13. Kaplan, E. L. and Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association 53, 457-481.
14. Lagakos, S. W. (1979). General right censoring and its impact on the analysis of survival data. Biometrics 35, 139-156.
15. Laird, N. M. and Ware, J. H. (1982). Random-effects models for longitudinal data. Biometrics 38, 963-974.
16. Laird, N. M., Donnelly, C., and Ware, J. H. (1992). Longitudinal studies with continuous responses. Statistical Methods in Medical Research 1, 3-25.
17. Little, R. J. A. (1993). Pattern-mixture models for multivariate incomplete data. Journal of the American Statistical Association 88, 125-134.
18. Little, R. J. A. (1995). Modeling the drop-out mechanism in repeated-measures studies. Journal of the American Statistical Association 90, 1112-1121.
19. Little, R. J. A. and Rubin, D. B. (1987). Statistical Analysis with Missing Data. New York: John Wiley and Sons.
20. McCarthy, D. (1972). Manual for the McCarthy Scales of Children's Abilities. Cleveland: The Psychological Corporation.
21. Mori, M., Woodworth, G. G., and Woolson, R. F. (1992). Application of empirical Bayes inference to estimation of rate of change in the presence of informative right censoring. Statistics in Medicine 11, 621-631.
22. Oakes, D., Moss, A. J., Fleiss, J. L., Bigger, J. T., Jr., Therneau, T., Eberly, S. W., McDermott, M. P., Manatunga, A., Carleen, E., Benhorin, J., and Multicenter Diltiazem Post-Infarction Trial Research Group. (1993). Use of compliance measures in an analysis of the effect of Diltiazem on mortality and reinfarction after myocardial infarction. Journal of the American Statistical Association 88, 44-49.
23. Pinheiro, J. C. and Bates, D. M. (1995). Mixed effects models and classes for S and SPlus. Technical Report 89, Department of Biostatistics, University of Wisconsin, Madison.
24. SAS Institute Inc. (1992). SAS/STAT Software: Changes and Enhancements, Release 6.07. Cary, North Carolina: SAS Institute Inc.
25. Schluchter, M. D. (1990). 5V: Unbalanced repeated measures models with structured covariance matrices. In BMDP Statistical Software Manual, Volume 2, W. J. Dixon (ed), 1207-1244, 1322-1327. Berkeley: University of California Press.
26. Schluchter, M. D. (1992). Methods for the analysis of informatively censored longitudinal data. Statistics in Medicine 11, 1861-1870.
27. Schwartz, D. and Lellouch, J. (1967). Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases 20, 637-648.
28. StatSci. (1991). S-Plus Reference Manual, Volume 2. Seattle: Statistical Sciences, Inc.
29. Wu, M. C. and Bailey, K. R. (1989). Estimation and comparison of changes in the presence of informative right censoring: Conditional linear model. Biometrics 45, 939-955.
30. Wu, M. C. and Carroll, R. J. (1988). Estimation and comparison of changes in the presence of informative right censoring by modeling the censoring process. Biometrics 44, 175-188.