Biomarkers of lung inflammation in recreational joggers exposed to ozone

American Journal of Respiratory and Critical Care Medicine

Volumn 154, Issue 5, 1996, Pages 1430-1435

  Kinney, Patrick L ^a   Nilsen, Diana M ^b   Lippmann, Morton ^b   Brescia, Michael ^b   Gordon, Terry ^b   Mcgovern, Tim ^b   El Fawal, Hassan ^b   Devlin, Robert B ^b   Rom, William N ^b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

OZONE;

ADULT; ARTICLE; BRONCHOSCOPY; CLINICAL ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; JOGGING; LUNG LAVAGE; MALE; PNEUMONIA; PRIORITY JOURNAL; SUMMER; WINTER;

EID: 0029846712     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.154.5.8912760     Document Type: Article

References (19)

1. Lippmann, M. 1989. Health effects of ozone. A critical review. J. Air Pollut. Control Assoc. 39:672-695.
2. Horstman, D. H., L. J. Folinsbee, P. J. Ives, S. Abdul-Salaam, and W. F. McDonnell. 1990. Ozone concentration and pulmonary response relationships for 6.6-hour exposures with five hours of moderate exercise to 0.08, 0.10, and 0.12 ppm. Am. Rev. Respir. Dis. 142: 1158-1163.
3. Koren, H. S., R. B. Devlin, D. E. Graham, R. Mann, M. P. McGee, D. H. Hortsman, W. J. Kozumbo, S. Becker, D. E. House, W. F. McDonnell, and P. A. Bromberg. 1989. Ozone-induced inflammation in the lower airways of human subjects. Am. Rev. Respir. Dis. 139:407-415.
4. Spektor, D. M., G. D. Thurston, J. Mao, D. He, C. Hayes, and M. Lippmann. 1991. Effects of single and multiday ozone exposures on respiratory function in active normal children. Environ. Res. 55: 107-122.
5. 3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J. Appl. Physiol. 60:1321-1326.
6. Aris, R. M., D. Christian, P. Q. Hearne, K. Kerr, W. E. Finkbeiner, and J. R. Balmes. 1993. Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am. Rev. Respir. Dis. 148:1363-1372.
7. Devlin, R. B., W. F. McDonnell, R. Mann, S. Becker, D. E. House, D. Schreinemachers, and H. S. Koren. 1991. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am. J. Respir. Cell Mol. Biol. 4:72-81.
8. Folinsbee, L. J., R. B. Devlin, and H. S. Koren. 1994. Time course of pulmonary response to repeated ozone exposure in man (abstract). Am. J. Respir. Crit. Care Med. 149(Part 2):A151.
9. Crapo, R. O., A. H. Morris, and R. M. Gardner. 1981. Reference spirometric values for spirometry using techniques and equipment that meet ATS recommendations. Am. Rev. Respir. Dis. 123:659-664.
10. Easmon, C. S. F., P. J. Cole, A. J. Williams, and M. Hastings. 1980. The measurement of opsonic and phagocytic funciton by luminol-dependent chemiluminescence. Immunology 41:67-74.
11. Ogunbiyi, P. O., P. D. Conlon, W. D. Black, and P. Eyre. 1988. Levamisole-induced attenuation of alveolar macrophage-dysfunction in respiratory virus-infected calves. Int. J. Immunopharmacol. 10: 377-385.
12. Leonard, E. J., and T. Yoshimura. 1990. Neutrophil attractant/activation protein 1(NAP-1[Interleukin 8]). Am. J. Respir. Cell Mol. Biol. 2:479-486.
13. Stieter, R. M., K. Kasahara, R. M. Allen, T. J. Standiford, M. W. Rolfe, F. S. Becker, S. W. Chensue, and S. L. Kunkel. 1992. Cytokine-induced neutrophil-derived interleukin-8. Am. J. Pathol. 141:397-407.
14. Carré, P. C., R. L. Mortenson, T. W. King, Jr., P. W. Noble, C. L. Sable, and D. W. H. Riches. 1991. Increased expression of interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis. J. Clin. Invest. 88:1802-1810.
15. Ryer-Powder, J. E., M. A. Amoruso, B. Czerniecki, G. Witz, and B. D. Goldstein. 1988. Inhalation of ozone produces a decrease in superoxide anion radical production in mouse alveolar macrophages. Am. Rev. Respir. Dis. 138:1129-1133.
16. Morrison, D., A. Langridge, I. Rahman, and W. MacNee. 1995. Epithelial permeability, inflammation and oxidant status in the air spaces of non-smokers exposed to ozone (abstract). Am. J. Respir. Crit. Care Med. 151(Part 2):A27.
17. Voter, K. Z., J. C. Whitin, M. J. Utell, Y. Tsai, P. E. Morrow, and M. W. Frampton. 1995. Superoxide anion generation by bronchoalveolar lavage cells from smokers and nonsmokers exposed to ozone (abstract). Am. J. Respir. Crit. Care Med. 151(Part 2):A26.
18. Driscoll, K. E., T. A. Vollmuth, and R. B. Schlesinger. 1987. Acute and subchronic ozone inhalation in the rabbit: response of alveolar macrophages. J. Toxicol. Environ. Health 21:27-43.
19. Everson, R. B., D. M. Schreinemachers, R. B. Devlin, and H. S. Koren. 1994. Host determinants of cellular and biochemical constituents of bronchial lavage fluids: implications for design of epidemiologic studies. Am. J. Respir. Crit. Care Med. 149:899-904.