Immunisation of common marmosets with vaccinia virus expressing Epstein-Barr virus (EBV) gp340 and challenge with EBV

Journal of Medical Virology

Volumn 50, Issue 3, 1996, Pages 263-271

  Mackett, Mike ^a   Cox, Charles ^b,c   Pepper, Stuart De V ^a   Lees, Janice F ^a   Naylor, Beverley A ^b   Wedderburn, Nina ^b,c   Arrand, John R ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b ROYAL COLLEGE OF SURGEONS OF ENGLAND   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Gp340; M81; Membrane antigen; Vaccinia recombinant

Indexed keywords

CYCLOSPORIN A; VIRUS GLYCOPROTEIN; VIRUS VACCINE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EPSTEIN BARR VIRUS; FEMALE; IMMUNIZATION; IMMUNOFLUORESCENCE; INFECTIOUS MONONUCLEOSIS; MALE; MARMOSET; NONHUMAN; VACCINIA VIRUS; VIRUS RECOMBINANT;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; CALLITHRIX; CELL LINE; DISEASE MODELS, ANIMAL; DNA, VIRAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENETIC VECTORS; HERPESVIRUS 4, HUMAN; IMMUNIZATION; INFECTIOUS MONONUCLEOSIS; MALE; MOLECULAR SEQUENCE DATA; MOUTH MUCOSA; VACCINES, SYNTHETIC; VACCINIA VIRUS; VIRAL MATRIX PROTEINS; VIRAL VACCINES;

ANIMALIA; CALLITHRIX JACCHUS; GOSSYPIUM HIRSUTUM; HUMAN HERPESVIRUS 4; MARMOSETS; SAGUINUS IMPERATOR; SAGUINUS OEDIPUS; VACCINIA; VACCINIA VIRUS;

EID: 0029846309     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(199611)50:3<263::AID-JMV9>3.0.CO;2-7     Document Type: Article

References (49)

1. Baer R, Bankier AT, Biggin MD, Deininger PL, Farrell PJ, Gibson TJ, Hatfull G, Hudson GS, Satchwell SC, Seguin C, Tuffnell PS, Barrell BG (1984): DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 310:207-211.
2. Bauer G (1983): Quantitative analysis of the cooperative effect between inducers of Epstein-Barr virus antigen synthesis. Journal of General Virology 64:1337-1346.
3. Beisel C, Tanner J, Matsuo T, Thorley-Lawson D, Kezdy F, Kieff E (1985): Two major outer envelope glycoproteins of Epstein-Barr virus are encoded by the same gene. Journal of Virology 54:665-674.
4. Biggin M, Farrell PJ, Barrell BG (1984): Transcription and DNA sequence of the BamHI L fragment of B95-8 Epstein-Barr virus. EMBO Journal 3:1083-1090.
5. Chen XY, Pepper S de V, Arrand JR (1992): Prevalence of the A and B types of Epstein-Barr virus DNA in nasopharyngeal carcinoma biopsies from southern China. Journal of General Virology 73: 463-466.
6. Cleary ML, Epstein MA, Finerty S, Dorfman RF, Bornkamm GW, Kirkwood JK, Morgan AJ, Sklar J (1985): Individual tumors of multifocal EB virus-induced malignant lymphomas in tamarins arise from different B-cell clones. Science 228:722-724.
7. Conway M, Morgan AJ, Mackett M (1989): Expression of Epstein-Barr virus membrane antigen gp340/220 in mouse fibroblasts using a bovine papillomavirus vector. Journal of General Virology 70: 729-734.
8. Cox C, Chang S, Karran L, Griffin B, Wedderburn N (1996): Persistent Epstein-Barr virus infection in the common marmoset (Callithrax jacchus) Journal of General Virology 77:1173-1180.
9. de Thé G, Ho HC, Kwan HC, Desgranges C, Favre MC (1970): Nasopharyngeal carcinoma (NPC). I. Types of cultures derived from tumour biopsies and non-tumorous tissues of Chinese patients with special reference to lymphoblastoid transformation. Inernational Journal of Cancer 6:189-206.
10. de Thé G, Geser A, Day NE, Tukei PM, Williams EH, Beri DP, Smith PG, Dean AG, Bronkamm GW, Feorino P, Henle W (1978): Epidemiological evidence for causal relationships between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study. Nature 274:756-761.
11. de Thé G, Dubouch P, Fontaine C, Wedderburn N, Carter RL, Edwards MB, Cohen B (1980): Natural antibodies to EBV-VCA antigens in common marmosets (Callithrix jacchus) and response after EBV inoculation. Intervirology 14:284-291.
12. Desgranges C, Lenoir G, de Thé G, Seigneurin JM, Hilgers J, Dubouch P (1976): In vitro transforming activity of EBV. I. Establishment and properties of two EBV strains (M81 and M72) produced by immortalized Callithrix jacchus lymphocytes. Biomedicine 25: 349-352.
13. Desgranges C, Lavoue MF, Patet J, de Thé G (1979): In vitro transforming activity of Epstein-Barr virus (EBV). II. Differences between M81 and B95-8 EBV strains. Biomedicine 30:102-108.
14. Emini EA, Luka J, Armstrong ME, Banker FS, Provost PJ, Pearson GR (1986): Establishment and characterization of a chronic infectious mononucleosis like syndrome in common marmosets. Journal of Medical Virology 18:369-379.
15. Epstein MA, Morgan AJ, Finerty S, Randle BJ, Kirkwood JK (1985): Protection of cottontop tamarins against Epstein-Barr virus-induced malignant lymphoma by a prototype subunit vaccine. Nature 318:287-289.
16. Epstein MA, Randle BJ, Finerty S, Kirkwood JK (1986): Not all potently neutralizing, vaccine-induced antibodies to Epstein-Barr virus ensure protection of susceptible experimental animals. Clinical and Experimental Immunology 63:485-490.
17. Felton SC, Hoffmann CC, Kreier JP, Glaser R (1984): Hematologic and immunologic responses in common marmosets (Calllithrix jacchus) infected with Plasmodium knowlesi and Epstein-Barr virus. Laboratory Animal Sciences 34:164-168.
18. Finerty S, Tarlton J, Mackett M, Conway M, Arrand JR, Watkins PE, Morgan AJ (1992): Protective immunization against Epstein-Barr virus-induced disease in cottontop tamarins using the virus envelope glycoprotein gp340 produced from a bovine papillomavirus expression vector. Journal of General Virology 73:449-453.
19. Finerty S, Mackett M, Arrand JR, Watkins PE, Tarlton J, Morgan AJ (1994): Immunization of cottontop tamarins and rabbits with a candidate vaccine against the Epstein-Barr virus based on the major viral envelope glycoprotein gp340 and alum. Vaccine 12:1180-1184.
20. Greenspan JS, Greenspan D, Lennette ET, Abrams DI, Conant MA, Petersen V, Freese UK (1985): Replication of Epstein-Barr virus within the epithelial cells of oral "hairy" leukoplakia, an AIDS-associated lesion. New England Journal of Medicine 313:1564-1571.
21. Greenspan D, Greenspan JS, de Souza Y, Levy JA, Ungar AM (1989): Oral hairy leukoplakia in an HIV-negative renal transplant recipient. Journal of Oral Pathology and Medicine 18:32-34.
22. Gu SY, Huang TM, Ruan L, Miao YH, Lu H, Chu CM, Motz M, Wolf H (1995). First EBV vaccine trial in humans using recombinant vaccinia virus expressing the major membrane antigen. Developments in Biological Standardisation 84:171-177.
23. Hanto DW, Frizzera G, Purtilo DT, Sakamoto K, Sullivan JL, Saemundsen AK, Klein G, Simmons RL, Najarian JS (1981): Clinical spectrum of lymphoproliferative disorders in renal transplant recipients and evidence for the role of Epstein-Barr virus. Cancer Research 41:4253-4261.
24. Henle G, Henle W (1966): Immunofluorescence in cells derived from Burkitt's lymphoma. Journal of Bacteriology 91:1248-1256.
25. Herbst H, Niedobitek G, Kneba M, Hummel M, Finn T, Anagnostopoulos I, Bergholz M, Krieger G, Stein H (1990): High incidence of Epstein-Barr virus genomes in Hodgkin's disease. American Journal of Pathology 137:13-18.
26. Imai S, Koizumi S, Sugiura M, Tokunaga M, Uemura Y, Yamamoto N, Tanaka S, Sato E, Osato T (1994): Gastric carcinoma: monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein. Proceedings of the National Academy of Sciences USA 91:9131-9135.
27. Israel ZR, Edmonson PF, Maul DH, O'Neil SP, Mossman SP, Thiriart C, Fabry L, van Opstal O, Bruck C, Bex F, Burny A, Fultz PN, Mullins JI, Hoover EA (1994): Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines. Journal of Virology 68:1843-1853.
28. Johnston DA, Knight AM, Naylor BA, Wedderburn N, Mitchell GH (1990): Monoclonal antibodies from Epstein-Barr virus-transformed lymphocytes of common marmosets (Callithrix jacchus) immune to malaria. Journal of Immunological Methods 127:187-195.
29. Labrecque LG, Barnes DM, Fentiman IS, Griffin BE (1995): Epstein-Barr virus in epithelial cell tumors: a breast cancer study. Cancer Research 55:39-45.
30. Lees JF, Arrand JE, Peppers de V, Stewart JP, Mackett M, Arrand JR (1993): The Epstein-Bar virus candidate vaccine antigen gp340/220 is highly conserved between virus types A and B. Virology 195: 578-586.
31. Mackett M, and Arrand JR (1985): Recombinant vaccinia virus induces neutralising antibodies in rabbits against Epstein-Barr virus membrane antigen gp340. EMBO Journal 4:3229-3234.
32. Morgan AJ, Finerty JS, Lovgren K, Scullion FT, Morein B (1988a): Prevention of Epstein-Barr (EB) virus-induced lymphoma in cottontop tamarins by vaccination with the EB virus envelope glycoprotein gp340 incorporated into immune-stimulating complexes. Journal of General Virology 69:2093-2096.
33. Morgan AJ, Mackett M, Finerty S, Arrand JR, Scullion FT, Epstein MA (1988b): Recombinant vaccinia virus expressing Epstein-Barr virus glycoprotein gp340 protects cottontop tamarins against EB virus-induced malignant lymphomas. Journal of Medical Virology 25:189-195.
34. Morgan AJ, Allison AC, Finerty S, Scullion FT, Byars NE, Epstein MA (1989): Validation of a first-generation Epstein-Barr virus vaccine preparation suitable for human use. Journal of Medical Virology 29:74-78.
35. Niedobitek G, Agathanggelou A, Finerty S, Tierney R, Watkins P, Jones EL, Morgan AJ, Young LS, Rooney N (1994): Latent Epstein-Barr virus infection in cottontop tamarins. A possible model for Epstein-Barr virus infection in humans. American Journal of Pathology 145:969-978.
36. North JR, Morgan AJ, Epstein MA (1980): Observations on the EB virus envelope and virus-determined membrane antigen (MA) polypeptides. International Journal of Cancer 26:231-240.
37. Parker BD, Bankier A, Satchwell S, Barrell B, Farrell PJ (1990): Sequence and transcription of Raji Epstein-Barr virus DNA spanning the B95-8 deletion region. Virology 179:339-346.
38. Pepper S de V, Stewart JP, Arrand JR, Mackett M (1996): Murine gammaherpesvirus-68 encodes homologues of thymidine kinase and glycoprotein H: sequence, expression and characterization of pyrimidine kinase activity. Virology 219:475-479.
39. Ragot T, Finerty S, Watkins PE, Perricaudet M, Morgan AJ (1993): Replication-defective recombinant adenovirus expressing the Epstein-Barr virus (EBV) envelope glycoprotein gp340/220 induces protective immunity against EBV-induced lymphomas in the cottontop tamarin. Journal of General Virology 74:501-507.
40. Randle BJ, Epstein MA (1984): A highly sensitive enzyme-linked immunosorbent assay to quantitate antibodies to Epstein-Barr virus membrane antigen gp340. Journal of Virological Methods 9:201-208.
41. Sutjipto S, Pedersen NC, Miller CJ, Gardner MB, Hanson CV, Gettie A, Jennings M, Higgins J, Marx PA (1990): Inactivated simian immunodeficiency virus vaccine failed to protect rhesus macaques from intravenous or genital mucosal infection but delayed disease in intravenously exposed animals. Journal of Virology 64:2290-2297.
42. Tanner J, Whang Y, Sample J, Sears A, Kieff E (1988): Soluble gp350/ 220 and deletion mutant glycoproteins block Epstein-Barr virus adsorption to lymphocytes. Journal of Virology 62:4452-4464.
43. Thomas JA, Crawford DH (1989): Epstein-Barr virus associated B-cell lymphomas in AIDS and after organ transplantation. Lancet 1:1075-1076.
44. Ulaeto D, Wallace L, Morgan AJ, Morein B, Rickinson AB (1988): In vitro T cell responses to a candidate Epstein-Barr virus vaccine: human CD4+ T cell clones specific for the major envelope glycoprotein gp340. European Journal of Immunology 18:1689-1697.
45. Wallace LE, Wright J, Ulaeto DO, Morgan AJ, Rickinson AB (1991): Identification of two T-cell epitopes on the candidate Epstein-Barr virus vaccine glycoprotein gp340 recognized by CD4+ T-cell clones. Journal of Virology 65:3821-3828.
46. Wedderburn N, Edwards JM, Desgranges C, Fontaine C, Cohen B, de Thé G (1984): Infectious mononucleosis-like response in common marmosets infected with Epstein-Barr virus. Journal of Infectious Diseases 150:878-882.
47. Weir JP, Moss B (1983): Nucleotide sequence of the vaccinia virus thymidine kinase gene and the nature of spontaneous frameshift mutations. Journal of Virology 46:530-537.
48. Weir JP, Bajszar G, Moss B (1982): Mapping of the vaccinia virus thymidine kinase gene by marker rescue and by cell-free translation of selected mRNA. Proceedings of the National Academy of Sciences USA 79:1210-1214.
49. zur Hausen H, Holthausen H, Schulte H, Klein G, Henle W, Henle G, Clifford P, Santesson L (1970): EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx. Nature 228:1056-1058.