Impact of cerebral perfusion pressure and autoregulation on intracranial dynamics: A modeling study

Neurosurgery

Volumn 39, Issue 5, 1996, Pages 1005-1015

  Giulioni, Marco ^a   Ursino, Mauro ^b  

^a BELLARIA HOSPITAL   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Autoregulation; Cerebral perfusion pressure; Intracranial pressure; Mathematical modeling; Pressure volume index; Secondary brain damage

Indexed keywords

ARTICLE; AUTOREGULATION; BRAIN BLOOD FLOW; BRAIN INJURY; BRAIN PERFUSION; HEMODYNAMIC MONITORING; INTRACRANIAL ANEURYSM; MATHEMATICAL MODEL; PRESSURE VOLUME CURVE; PRIORITY JOURNAL;

BLOOD PRESSURE; BLOOD VOLUME; CEREBROVASCULAR CIRCULATION; COMPUTER SIMULATION; HEMODYNAMIC PROCESSES; HOMEOSTASIS; HUMANS; INTRACRANIAL PRESSURE; MODELS, NEUROLOGICAL;

EID: 0029846276     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-199611000-00024     Document Type: Article

References (40)

1. Auer LM, Ishiyama N, Pucher R: Cerebrovascular response to intracranial hypertension. Acta Neurochir (Wien) 84:124-128, 1987.
2. Avezaat CJJ, van Eijndhoven JHM, Wyper DJ: Cerebrospinal fluid pulse pressure and intracranial volume-pressure relationship. J Neurol Neurosurg Psychiatry 42:687-700, 1979.
3. Avezaat CJJ, van Eijndhoven JHM, Wyper DJ: Effects of hypercapnia and arterial hypotension and hypertension on cerebrospinal fluid pulse pressure and intracranial volume-pressure relationship. J Neurol Neurosurg Psychiatry 43:222-234, 1980.
4. Bouma GJ, Muizelaar JP, Bandoh K, Marmarou A: Blood pressure and intracranial pressure-volume dynamics in severe head injury: Relationship with cerebral blood flow. J Neurosurg 77:15-19, 1992.
5. Bouma GJ, Muizelaar JP, Choi SC, Newlon PG, Young HF: Cerebral circulation and metabolism after severe traumatic brain injury: The elusive role of ischemia. J Neurosurg 75:685-693, 1991.
6. Bouma GJ, Muizelaar JP, Stringer WA, Choi SC, Newlon PG, Fatourus P, Young HF: Ultra-early evaluation of regional blood flow in severely head injured patients using xenon-enhanced computerized tomography. J Neurosurg 77:360-368, 1992.
7. Chan KH, Dearden NM, Miller JD, Andrews PJD, Midgley S: Multimodality monitoring: ASA guide to treatment of intracranial hypertension after severe brain injury. Neurosurgery 32:547-553, 1993.
8. Chan KH, Miller JD, Dearden NM, Andrews PJ, Midgley S: The effect of changes in cerebral perfusion pressure upon middle cerebral artery blood flow velocity and jugular bulb venous oxygen saturation after severe brain injury. J Neurosurg 77:55-61, 1992.
9. 2 cerebrovascular reactivity as a function of perfusion pressure: A modelling study. Acta Neurochir (Wien) 121:159-165, 1993.
10. Fung YC: Biodynamics: Circulation. New York, Springer-Verlag, 1984.
11. Giulioni M, Ursino M, Alvisi C: Correlation among intracranial pulsatility, intracranial hemodynamics, and transcranial Doppler wave form: Literature review and hypothesis for future studies. Neurosurgery 22:807-812, 1988.
12. Gray WJ, Rosner MJ: Pressure-volume index as a function of cerebral perfusion pressure: Part 1 - The effects of cerebral perfusion pressure changes and anesthesia. J Neurosurg 67:369-376, 1987.
13. Gray WJ, Rosner MJ: Pressure-volume index as a function of cerebral perfusion pressure: Part 2 - The effects of low cerebral perfusion pressure and autoregulation. J Neurosurg 67:377-380, 1987.
14. Gustafsson O, Rossitti S: Intracranial pressure is a fraction of arterial blood pressure. Eur J Neurol 2:31-37, 1995.
15. Hoffman H: Biomathematics of intracranial CSF and hemodynamics: Simulation and analysis with the aid of a mathematical model. Acta Neurochir Suppl (Wien) 40:117-130, 1987.
16. Kontos HA, Wei EP, Navari RM, Levasseur JE, Rosenblum WI, Patterson JL: Responses of cerebral arteries and arterioles to acute hypotension and hypertension. Am J Physiol 234:H371-H383, 1978.
17. Langfitt TW, Weinstein JD, Kassel NF: Cerebral vasomotor paralysis produced by intracranial hypertension. Neurology 15:622-641, 1965.
18. Leech P, Miller JD: Intracranial pressure-volume relationships during experimental brain compression in primates: Part 2 - Effects of induced changes in systemic arterial pressure and cerebral blood flow. J Neurol Neurosurg Psychiatry 37:1099-1104, 1974.
19. MacKenzie ET, Farrar JK, Fitch W, Graham DI, Gregory PC, Harper AM: Effects of hemorrhagic hypotension on the cerebral circulation: Part 1 - Cerebral blood flow and pial arteriolar caliber. Stroke 10:711-718, 1979.
20. Marmarou A, Anderson RL, Ward JD, Choi SC, Young HF, Eisenberg HM, Foulkes MA, Marshall LF, Jane JA: Impact of ICP instability and hypotension on outcome in patients with severe head trauma. J Neurosurg 75[Suppl]:S59-S66, 1991.
21. Marmarou A, Maset AL, Ward JD, Choi S, Brooks D, Lutz HA, Moulton R, Muizelaar JP, De Salles A, Young F: Contribution of CSF and vascular factors to elevation of ICP in severely head-injured patients. J Neurosurg 66:883-890, 1987.
22. Marmarou A, Shulman K, LaMorgese J: Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system. J Neurosurg 43:523-534, 1975.
23. Mchedlishvili G: Arterial Behavior and Blood Circulation in the Brain. New York, Plenum Press, 1986.
24. Miller JD: Head injury and brain ischemia: Implications for therapy. Br J Anaesth 57:120-129, 1985.
25. Miller JD, Dearden NM, Piper IR, Chan KH: Control of intracranial pressure in patients with severe head injury. J Neurotrauma 9[Suppl 1]:S317-S326, 1992.
26. Muizelaar JP, Ward JD, Marmarou A, Newlon PG, Wachi A: Cerebral blood flow and metabolism in severely head-injured children: Part 2 - autoregulation. J Neurosurg 71:72-76, 1989.
27. Nakagawa Y, Tsuru M, Yada K: Site and mechanism for compression of the venous system during experimental intracranial hypertension. J Neurosurg 41:427-434, 1974.
28. Obrist WD, Langfitt TW, Jaggi JL, Cruz J, Gennarelli TA: Cerebral blood flow and metabolism in comatose patients with acute head injury: Relationship to intracranial hypertension. J Neurosurg 61:241-253, 1984.
29. Risberg J, Lundberg N, Ingvar DH: Regional cerebral blood volume during acute transient rises of the intracranial pressure (plateau waves). J Neurosurg 31:303-310, 1969.
30. Robertson CS, Narayan RK, Contant CF, Grossman RG, Gokaslan ZL, Pahwa R, Caram P Jr, Bray RS Jr, Sherwood AM: Clinical experience with a continuous monitor of intracranial compliance. J Neurosurg 71:673-680, 1989.
31. Rosner MJ, Becker DP: Origin and evolution of plateau waves: Experimental observations and a theoretical model. J Neurosurg 60:312-324, 1984.
32. Rosner MJ, Becker DP: Cerebral perfusion pressure: Link between intracranial pressure and systemic circulation, in Wood JH (ed): Cerebral Blood Flow: Physiological and Clinical Aspects. New York, McGraw-Hill, 1987, pp 425-448.
33. Sorek S, Bear J, Karni Z: Resistances and compliances of a compartmental model of the cerebrovascular system. Ann Biomed Eng 17:1-12, 1989.
34. 2 upon bulk compliance (PVI), in Shulman K, Marmarou A, Miller JD (eds): Intracranial Pressure IV. Berlin, Springer-Verlag, 1980, pp 163-166.
35. Takemae T, Kosugi Y, Ikebe J, Kumagai Y, Matsuyama K, Saito H: A simulation study of intracranial pressure using an electrical circuit model of cerebral circulation. IEEE Trans Biomed Eng 34:958-962, 1987.
36. Ursino M: A mathematical study of human intracranial hydrodynamics: Part 1 - The cerebrospinal fluid pulse pressure. Ann Biomed Eng 16:379-402, 1988.
37. Ursino M: A mathematical study of human intracranial hydrodynamics: Part 2 - Simulation of clinical tests. Ann Biomed Eng 16:403-416, 1988.
38. Ursino M, Di Giammarco P: A mathematical model of the relationship between cerebral blood volume and intracranial pressure changes: The generation of plateau waves. Ann Biomed Eng 19:15-42, 1991.
39. Ursino M, Giulioni M: Computer analysis of intracranial pressure pulsatility and blood flow shape during intracranial hypertension, in Avezaat CJJ, van Eijndhoven JHM, Maas AIR, Tans JTJ (eds): Intracranial Pressure VIII. Berlin, Springer-Verlag, 1993, pp 394-397.
40. Ursino M, Iezzi M, Stocchetti N: Intracranial pressure dynamics in patients with acute brain damage: A critical analysis with the aid of a mathematical model. IEEE Trans Biomed Eng 42:529-540, 1995.