Stimulated secretion of lysosomal enzymes induced by drugs in transimmortalized proximal tubule mouse kidney cells

Cell Biology and Toxicology

Volumn 12, Issue 4-6, 1996, Pages 299-303

  Vandewalle, A ^a  

^a INSERM   (France)

Author keywords

aminoside; cell culture; kidney; lysosomal enzymes; proximal tubule

Indexed keywords

GENTAMICIN; LYSOSOME ENZYME;

ANIMAL CELL; CELL CULTURE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; ENZYME RELEASE; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; MUS MUSCULUS;

EID: 0029845819     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00438161     Document Type: Conference Paper

References (26)

1. Blais A, Morvan-bayeynaud J, Friedlander G, Le grimellec C. Primary culture of rabbit proximal tabules as a cellular model to study nephrotoxicity of xenobiotics. Kidney Int. 1993;44:13-8.
2. Bohets HH, Van Thielen MN, Van Der Biest I et al. Cytotoxicity of mercury compounds in LLC-PK1, MDCK and human proximal tubular cells. Kidney Int. 1995;47:395-403.
3. Bourbouze R, Dubois M, Gluckman JC, Legrain M. Excretion of urinary N-acetyl-β-D-glucuronidase isoenzymes after renal transplantation in the rat. J Clin Chem Clin Biochem. 1987;25:71-6.
4. Briand P, Kahn A, Vandewalle A. Targeted oncogenesis: a powerful method to derive renal cell lines. Kidney Int. 1995;47:388-94.
5. Cartier N, Lacave R, Vallet V et al. Establishment of proximal tubule cell lines by targeted oncogenesis in transgenic mice using the L-pyruvate kinase-SV40 (T) antigen hybrid gene. J Cell Sci. 1993;104:695-704.
6. De Broe ME, Verpooten GA, Giuliano RA et al. In: Klastersky J, ed. Controversial aspects of aminoglycoside therapy. EORTC symposium, Brussels; 1982:34-45.
7. Ernest S, Bello-Reuss E. Expression and function of P-glycoprotein in a mouse kidney cell line. Am J Physiol. 1995;269: C323-33.
8. Gonzalez-Noriega A, Grubb JH, Talkad V, Sly WS. Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling. J Cell Biol. 1980;85:839-52.
9. Gottesman M, Pastan I. The multidrug transporter, a double-edged sword. J Biol Chem. 1988;263:12163-6.
10. Gros P, Croop J, Housman D. Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell. 1986;47: 371-80.
11. Horio M, Chin K, Currier SJ et al. Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia. Proc Natl Acad Sci USA. 1989;264:14880-4.
12. 1). Am J Physiol. 1988;254:C251-7.
13. Lacave R, Bens M, Cartier N et al. Functional characteristics of proximal tubule cell lines derived from transgenic mice harboring L-pyruvate kinase-SV40 (T) antigen hybrid gene. J Cell Sci. 1993;104:705-12.
14. Naruse T, Hirokawa N, Oike S, Maekawa T. Clinical evaluation of urinary N-acetyl-β-D-glucosaminidase activity in patients receiving aminoglycoside and cephalosporin drugs. Res Commun Chem Pathol Pharmacol. 1981;31:313-29.
15. Ransammy LS, Josepovitz B, Lane GJ, Kaloyanides GJ. Effect of gentamicin on phospholipid metabolism in cultured proximal tubular cells. Am J Physiol. 1990;256:C204-13.
16. Riccaldi D, Robic D, Bens M et al. Cultured proximal cells derived from transgenic mouse provide model to study drug toxicity. Kidney Int. 1995;48:722-30.
17. 1) cells in culture. J Pharmacol Exp Ther. 1986;236:254-62.
18. Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA. 1987;4:7735-8.
19. Tremp GL, Boquet D, Ripoche MA et al. Expression of the rat L-type pyruvate kinase gene from its dual erythroid- and liver-specific promoter in transgenic mice. J Biol Chem. 1989;264:19904-10.
20. Tulkens PM, De Broe ME, Maldague P, Heuson-Stiennon J. Lysosomal alterations in aminoglycoside-induced acute renal failure. In: Solez K, Whelton A, eds. Acute renal failure: correlation between morphology and function. New York: Marcel Dekker; 1984:299-327.
21. Vallet V, Bens M, Antoine B et al. Transcription factors and aldolase B gene expression in microdissected tubules and derived cell lines. Exp Cell Res. 1995;216:363-70.
22. Voisin T, Bens M, Cluzeaud F, Vandewalle A, Laburthe M. Peptide YY receptors in the proximal tubule PKSV-PCT cell line derived from transgenic mice - relation with cell growth. J Biol Chem. 1993;268:20547-54.
23. 12 proteins in renal proximal tubule cells. J Biol Chem. 1996;271:574-80.
24. +-adenosine triphosphatase by gentamicin. J Pharmacol Exp Ther. 1984;231: 248-53.
25. Willcox P, Rattray S. Secretion and uptake of β-N acetylglucosaminidase by fibroblasts. Biochim Biophys Acta. 1979;586: 442-52
26. Willingham MC, Cornwell MM, Cardarelli CO, Gottesmann MM, Pastan I. Single-cell analysis of daunomycin uptake and efflux in multidrug-resistant and -sensitive KB cells: effects of verapamil. Cancer Res. 1986;46:5941-6.