Suppression of tumorigenicity in Ras-transformed fibroblasts by α2(I) collagen

Cell Growth and Differentiation

Volumn 7, Issue 10, 1996, Pages 1353-1360

  Travers, Helen ^a,b   French, Neil S ^a   Norton, John D ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL TRANSFORMATION; COLLAGEN METABOLISM; CONTROLLED STUDY; CYTOSKELETON; EXTRACELLULAR MATRIX; FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; CELL ADHESION; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; COLLAGEN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; MICE; SIGNAL TRANSDUCTION;

ANIMALIA; MUS MUSCULUS;

EID: 0029845481     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. Galang, C. K., Der, C. J., and Hauser, C. A. Oncogenic ras can induce transcriptional activation through a variety of promoter elements, including tandem c-ets-2 binding sites. Oncogene, 9: 2913-2921, 1994.
2. Aoyama, A., and Klemenz, R. Oncogene-mediated effects on cellular gene expression. Crit. Rev. Oncog., 4: 53-94, 1993.
3. Bortner, D. M., Langer, S. J., and Ostrowski, M. C. Non-nuclear oncogenes and the regulation of gene expression in transformed cells. Crit. Rev. Oncog., 4: 137-160, 1993.
4. Chambers, A. F., and Tuck, A. B. Ras-responsive genes and tumor metastasis. Crit. Rev. Oncog., 4: 95-114, 1993.
5. Willingham, M. C., Yamada, K. M., Yamada, S. S., Pouysségur, J., and Pastan, J. Microfilament bundles and cell shape are related to adhesiveness to substratum and are dissociable from growth control in cultured fibroblasts. Cell, 10: 375-380, 1977.
6. Chambers, A. F., Hota, C., and Prince, C. W. Adhesion of metastatic, ras-transformed NIH 3T3 cells to osteoponin, fibronectin, and laminin. Cancer Res., 53: 701-706, 1993.
7. Schwartz, M. A. Signaling by integrins: implications for tumorigenesis. Cancer Res., 53: 1503-1506, 1993.
8. Giancotti, F. G., and Mainiero, F. Integrin-mediated adhesion and signalling in tumorigenesis. Biochim. Biophys. Acta, 1198: 47-64, 1994.
9. Plantefaber, L. C., and Hynes, R. O. Changes in integrin receptors on oncogenically transformed cells. Cell, 56: 281-290, 1989.
10. 1/2fibroblasts. Cancer Res., 50: 4061-4066, 1990.
11. Fernadez, J. L. R., Geiger, B., Salomon, D., and Ben-Ze'ev, A. Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells. J. Cell Biol., 122: 1285-1294, 1993.
12. Eiden, M. V., MacArthur, L., and Okayama, H. Suppression of the chemically transformed phenotype of BHK cells by a human cDNA. Mol. Cell. Biol., 11: 5321-5329, 1991.
13. Fernadez, J. L. R., Geiger, B., Salomon, D., Sabana, I., Zoller, M., and Ben-Ze'ev, A. Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA. J. Cell Biol., 119: 427-438, 1992.
14. Gluck, U., Kwiatkowski, D. J., and Ben-Ze'ev, A. Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with a-actinin cDNA. Proc. Natl. Acad. Sci. USA, 90: 383-387, 1993.
15. Steel, D. M., and Harris, H. The effect of antisense RNA to fibronectin on the malignancy of hybrids between melanoma cells and normal fibroblasts. J. Cell Sci., 93: 515-524, 1989.
16. Pienta, K. J., Murphy, B. C., Getzenberg, R. H., and Coffey, D. S. The effect of extracellular matrix interactions on morphological transformation in vitro. Biochem. Biophys. Res. Commun., 179: 333-339, 1991.
17. Yamada, K. M., Yamada, S. S., and Pastan, I. Cell surface protein partially restores morphology, adhesiveness, and contact inhibition of movement to transformed fibroblasts. Proc. Natl. Acad. Sci. USA, 73: 1217-1221, 1977.
18. Vlodavsky, I., Lui, G. M., and Gos Podarowicz, D. Morphological appearance, growth behavior, and migratory activity of human tumor cells maintained on extracellular matrix versus plastic. Cell, 19: 607-616, 1980.
19. Ali, I. U., Mautner, V., Lanza, R., and Hynes, R. O. Restoration of normal morphology, adhesion, and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein. Cell, 11: 115-126, 1977.
20. Bornstein, P., and Sage, H. Structurally distinct collagen types. Annu. Rev. Biochem., 49: 957-1003, 1980.
21. Bornstein, P., and Sage, H. Regulation of collagen gene expression. Prog. Nucleic Acid Res. Mol. Biol., 37: 67-106, 1989.
22. Sonnenberg, A. Integrins and their ligands. Curr. Top. Microbiol. Immunol., 186: 7-26, 1993.
23. Haas, T., and Plow, E. F. Integrin ligand interactions - a year in review. Curr. Opin. Cell Biol., 6: 656-662, 1994.
24. Juliano, R. L., and Haskill, S. Signal transduction from the extracellular matrix. J. Cell Biol., 120: 577-584, 1993.
25. Zachary, I., and Rosengurt, E. Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes. Cell, 71: 891-894, 1992.
26. Hanks, S. K., Calalb, M. B., Harper, M. C., and Patel, S. K. Focal adhesion protein tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc. Natl. Acad. Sci. USA, 89: 8487-8491, 1992.
27. Parker, M. I., Smith, A. A., and Gevers, W. Absence of α2(1) procollagen synthesis in a clone of SV40-transformed WI-38 human fibroblasts. J. Biol. Chem., 264: 7147-7152, 1989.
28. Jimenez, S. A., Varga, J., Olsen, A., Li, L., Diaz, A., Herhal, J., and Koch, J. Functional analysis of human α-1 (1) procollagen gene promoter-differential activity in collagen-producing and collagen-nonproducing cells and response to transforming growth factor β(1). J. Biol. Chem., 269: 12684-12691, 1994.
29. Slack, J. L., Parker, M. I., Robinson, V. R., and Bornstein, P. Regulation of collagen I gene expression by ras. Mol. Cell. Biol., 12: 4714-4723, 1992.
30. Gottesman, M. . Semin. Cancer Biol., 1: 97-160, 1990.
31. Matrisian, L. M. Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet., 6: 121-125, 1991.
32. Sundarraj, N., and Church, R. L. Alterations of post-translational modification of procollagen by SV40-transformed human fibroblasts. FEBS Lett., 85: 47-51, 1978.
33. Marsilio, E., Sobel, M., and Smith, B. Absence of procollagen α2(1) mRNA in chemically transformed rat liver epithelial cells. J. Biol. Chem., 259: 1401-1404, 1984.
34. Smith, B. D., and Niles, R. Characterization of collagen synthesized by normal and chemically transformed rat liver epithelial cell lines. Biochemistry, 19: 1820-1825, 1980.
35. Norton, J. D., Cook, F., Roberts, B. C., Clewley, J. P., and Avery, R. J. Expression of Kirsten murine sarcoma virus in transformed nonproducer and revenant NIH/3T3 cells: evidence for cell-mediated resistance to a viral oncogene in phenotypic reversion. J. Virol., 50: 439-444, 1984.
36. Eaton, L. T., and Norton, J. D. Independent regulation of mouse retrotransposon expression in suspension-arrested fibroblasts. Nucleic Acids Res., 18: 2069-2077, 1990.
37. Owen, R. D., Bortner, D. M., and Ostrowski, M. C. Ras oncogene activation of a VL30 transcriptional element is linked to transformation. Mol. Cell. Biol., 10: 1-9, 1990.
38. Lee, S. T., Smith, B. D., and Greenspan, D. S. Construction of a full-length cDNA encoding human pro-α2(1) collagen and its expression in pro-α2(1)-deficient W8 rat cells. J. Biol. Chem., 263: 13414-13418, 1988.
39. Hynes, R. O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell, 69: 11-25, 1992.
40. Juliano, R. Signal-transduction by integrins and its role in the regulation of tumor growth. Cancer Metastasis Rev., 13: 25-30, 1994.
41. 1, fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells. Cell, 60: 849-859, 1990.
42. Haimovich, B., Lipfert, L., Brugge, J. S., and Shattil, S. J. Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands. J. Biol. Chem., 268: 15868-15877, 1993.
43. Chen, Q., Kinch, M. S., Lin, T. H., Burridge, K., and Juliano, R. L. Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J. Biol. Chem., 269: 26602-26605, 1994.
44. Schlaepfer, D. D., Hanks, S. K., Hunter, T., and Van der Greer, P. Integrin-mediated signal transduction linked to ras pathway by GRB2 binding to focal adhesion kinase. Nature (Lond.), 372: 786-791, 1994.
45. Schaller, M. D., and Parsons, J. T. Focal adhesion kinase and associated proteins. Curr. Opin. Cell Biol., 6: 705-710, 1994.
46. Hulsken, J., Behrens, J., and Birchmeier, W. Tumor suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr. Opin. Cell Biol., 6: 711-716, 1994.
47. Knudson, A. G. Antioncogenes and human cancer. Proc. Natl. Acad. Sci. USA, 90: 10914-10921, 1993.
48. Narayanan, R., Lawlor, K. G., Schaapveld, R. Q. J., Cho, K. R., Vogelstein, B., Tran, P. B. V., Osborne, M. P., and Telang, N. T. Antisense RNA to the putative tumor suppressor gene DCC transforms RAT-1 fibroblasts. Oncogene, 7: 553-561, 1992.
49. Risinger, J. I., Berchuck, A., Kohler, M. F., and Boyd, J. Mutations of the E-cadherin gene in human gynecologic cancers. Nat. Genet., 7: 98-101, 1994.
50. Zhou, J., Mochizuki, T., Smets, H., Antignac, C., Laurila, P., DePaepe, A., Truggvasun, K., and Reeders, S. T. Deletion of the paired α5(IV) and α6(IV) collagen genes in inherited smooth muscle tumors. Science (Washington DC), 261: 1167-1169, 1993.
51. Yoshioka, K., Kono, T., Kitajima, J., Nakagawa, K., Yashiro, N., Taniguchi, S., Furukawa, M., and Hamada, T. Squamous cell carcinoma developing in epidermolysis bullosa dystrophica. Int. J. Dermatol., 30: 718-721, 1991.
52. Kuivaniemi, H., Tromp, G., Chu. M-L., and Prockop, D. J. Structure of a full-length cDNA clone for the pre-proα2(1) chain of human type I procollagen. Biochem. J., 252: 633-640, 1988.
53. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
54. Luckow, B., and Schutz, G. Cat constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res., 15: 5490, 1987.
55. Deed, R. W., Bianchi, S. M., Atherton, G. T., Johnston, D., Santibanez-Koref, M., Murphy, J. J., and Norton, J. D. An immediate early human gene encodes an Id-like helix loop helix protein and is regulated by protein kinase C activation in diverse cell types. Oncogene, 8: 599-607, 1993.
56. Harlow, E., and Lane, D. Antibodies: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1988.
57. Gorman, C. M., Moffat, L. F., and Howard, B. H. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol., 2: 1044-1051, 1982.
58. Liau, G., Yamada, Y., and de Crombrugghe, B. C. Coordinate regulation of the levels of type III and type I collagen messenger RNA in most but not all mouse fibroblasts. Biochem. J., 260: 531-536, 1985.