Marked increase in serum CA 19-9 level in patients with alcoholic cirrhosis: Report of four cases

European Journal of Gastroenterology and Hepatology

Volumn 8, Issue 11, 1996, Pages 1129-1131

  Mathurin, Philippe ^a   Cadranel, Jean François ^b   Bouraya, Dalila ^b   Bronstein, Jean Ariel ^a   Collot, Gerard ^b   Devergie, Bruno ^b   Poynard, Thierry ^a   Opolon, Pierre ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b Centre Hospitalier de Creil   (France)

Author keywords

Alcoholic cirrhosis; Alcoholic hepatitis; Serum CA 19 9 level

Indexed keywords

CA 19-9 ANTIGEN;

ALCOHOL LIVER CIRRHOSIS; ALCOHOL LIVER DISEASE; ARTICLE; CASE REPORT; DIAGNOSTIC VALUE; HUMAN; JAUNDICE; LIVER FUNCTION; PANCREAS CARCINOMA; PRIORITY JOURNAL; STOMACH CARCINOMA;

EID: 0029845148     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199611000-00019     Document Type: Article

References (17)

1. Pleskow DK, Berger HJ, Gyves J, Allen E, McLean A, Podolsky DK: Evaluation of a serological marker, CA 19-9 in the diagnosis of pancreatic cancer. Ann Intern Med 1989, 110:704-709.
2. Welfare M, Tanner A: CA 19-9 estimation in the assessment of pancreatic or biliary tract malignancy - what is the most efficient threshold value? Eur J Gastroenterol Hepatol 1991, 3:539-543.
3. Pearce S, Thornes H, Carr D, Tanner A: Diagnosis pitfall: interpretation of CA 19-9 concentrations in the presence of hepatic dysfunction. Gut 1994, 35:707-708.
4. Steinberg WM, Gelfand R, Anderson KK, Glenn J, Kurtzmann SH, Sindelar WF, et al: Comparison of the sensitivity and specificity of the CA 19-9 and carcinoembryonic antigen assays in detecting cancer of pancreas. Gastroenterology 1986, 90:491-494.
5. Craxi A, Patti C, Aragona E: Serum CA 19-9 levels in patients with hepatocellular carcinoma or cirrhosis. Ital J Gastroenterol 1985, 17:288-289.
6. Andriulli A, Gindro T, Piantino P: Prospective evaluation of the diagnosis efficacy of CA 19-9 assay as a marker for gastrointestinal cancer. Digestion 1986, 33:26-33.
7. Del Favero G, Fabris C, Panucti A, Basso D, Plebani M, Baccaglini U, et al.: Carbohydrate antigen 19-9 and carcinoembryonic antigen in pancreatic cancer. Bull Cancer 1986, 73(3):251-255.
8. Boirie Y, Thiéfin G, Diebold MD, Leutenegger M: Elévation importante de l'antigène CA 19-9 sérique au cours d'une hépatite alcoolique aiguë. Gastroenterol Clin Biol 1995, 19:738.
9. Griga T, May B: Alkoholtoxische, akute intrahepatische Cholestase mit reversibler Erhohung des Tumormarkers CA 19-9 bei chronisher Alkohepatitis. Zeitschr Gastroenterol 31(suppl. 2):62-63.
10. Paganuzzi M, Onetto M, Marroni P, Barone D, Conio M, Aste H, et al.: CA 19-9 and CA 50 in benign and malignant pancreatic and biliary diseases. Cancer 1988, 61:2100-2108.
11. Delmashio A, Vanzulli A, Sironi S, Castrucci M, Mellone R, Staudacher C, et al.: Pancreatic cancer versus chronic pancreatitis: diagnosis with CA 19-9 assessment, US, CT and CT-guided fine-needle biopsy. Radiology 1991, 178:95-99.
12. Encabo G, Ruibal A: Seric CA 19-9 levels in patients with non tumoral pathologies. Our experience in 892 cases. Bull Cancer 1986, 73:256-259.
13. Basso D, Meggiato T, Fabris C, Plebani M, Fogar P, Panozzo MP, et al.: Extra-hepatic cholestasis determines a reversible increase of glycoprotein tumor markers in benign and malignant diseases. Eur J Clin Invest 1992, 22:800-804.
14. Collazos J, Genolla J, Ruibal A: CA 19-9 in non-neoplasic liver diseases. A clinical and laboratory study. Clin Chim Acta 1992, 210:145-151.
15. Pines E, Slama JC, Holeman A, Ley G, Malbec D, Boudon P: Taux inhabituellement élevé du CA 19-9 au cours d'une pancréatite chronique. Gastroenterol Clin Biol 1995, 19:641-642.
16. Thomas P, Zamcheck N: Role of the liver in clearance and excretion of circulating carcinoembryonic antigen Dig Dis Sci 1983, 28:217-224.
17. Shuster J, Silverman M, Gold P: Metabolism of human carcinoembryonic antigen in xenogenic animals Cancer Res 1973, 33:65-68.