Preparation and absolute configurations of optical isomers of sodium 2- [[4-(3-methoxypropoxy)-3-methylpyridin-2-yl] methylsulfinyl]-1H-benzimidazole (E3810)

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 10, 1996, Pages 1853-1857

  Nochi, Shigeharu ^a   Kawai, Takatoshi ^a   Kawakami, Yoshiyuki ^a   Asakawa, Naoki ^a   Ueda, Norihiro ^a   Hayashi, Kenji ^a   Souda, Shigeru ^a  

^a EISAI CO LTD   (Japan)

Author keywords

absolute configuration; E3810; optical isomer; optical resolution; proton pump inhibitor; X ray crystallographic analysis

Indexed keywords

RABEPRAZOLE;

ARTICLE; DRUG CONFORMATION; DRUG EFFECT; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERISM; PEPTIC ULCER; PROTON TRANSPORT; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

EID: 0029845014     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.1853     Document Type: Article

References (13)

1. Morii M., Takata H., Fujisaki H., Takeguchi N., Biochem. Pharmacol., 39, 661-667 (1990).
2. Fujisaki H., Shibata H., Oketani K., Murakami M., Fujimoto M., Wakabayashi T., Yamatsu I., Yamaguchi M., Sakai H., Takeguchi N., Biochem. Pharmacol., 42, 321-328 (1991).
3. Fujisaki H., Oketani K., Shibata H., Murakami M., Fujimoto M., Wakabayashi T., Yamatsu I., Takeguchi N., Nippon Yakurigaku Zasshi, 102, 389-397 (1993).
4. Tomiyama Y., Morii M., Takeguchi N., Biochem. Pharmacol., 48, 2049-2055 (1994).
5. Morii M., Hamatani K., Takeguchi N., Biochem. Pharmacol., 49, 1729-1734 (1995).
6. Yasuda S., Ohnishi A., Ogawa T., Tomono Y., Hasegawa J., Nakai H., Shimamura Y., Morishita N., Int. J. Clin. Pharmacol. Ther., 32, 466-473 (1994).
7. Kohl B., Senn-Bilfinger J., Ger. Offen. DE 40 35 455 Al (1992).
8. Fujisaki H. (Eisai Co., Ltd.), Fujimoto M. (Eisai Co., Ltd.), unpublished results.
9. Nochi S., Yokoyama Y., Narukawa M., Ebine K., Murahashi M., Kawakami Y., Asakawa N., Sato T., Chem. Pharm. Bull., 44, 552-558 (1996).
10. Souda S., Ueda N., Miyazawa S., Tagami K., Nomoto S., Okita M., Shimomura N., Kaneko T., Fujimolo M., Murakami M., Oketani K., Fujisaki H., Shibata H., Wakabayashi T., U.S. Patent 5045552 (1991).
11. CAD4-EXPRESS (VI.1), 1992, Delft Instruments X-Ray Diffraction, PO Box 811, 2600 AV Delft, Netherlands.
12. MOLEN, 1990, Delft Instruments X-Ray Diffraction B. V., Röntgenweg 1, 2624 BD Delft, Netherlands.
13. Giacovazzo C., Acta Crystallogr., Sect. A, A36, 362-372 (1980).