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Volumn 184, Issue 5, 1996, Pages 2061-2066

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLIP)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 0029845011     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.5.2061     Document Type: Article
Times cited : (72)

References (40)
  • 1
    • 0028038426 scopus 로고
    • MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
    • Germain, R.N. 1994. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell. 76:287-299.
    • (1994) Cell , vol.76 , pp. 287-299
    • Germain, R.N.1
  • 2
    • 0025331726 scopus 로고
    • Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
    • Roche, P.A., and P. Cresswell. 1990. Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding. Nature (Lond.). 345:615-618.
    • (1990) Nature (Lond.) , vol.345 , pp. 615-618
    • Roche, P.A.1    Cresswell, P.2
  • 4
    • 0028823585 scopus 로고
    • The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3
    • Ghosh, P., M. Amaya, E. Mellins, and D.C. Wiley. 1995. The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. Nature (Lond.). 378:457-462.
    • (1995) Nature (Lond.) , vol.378 , pp. 457-462
    • Ghosh, P.1    Amaya, M.2    Mellins, E.3    Wiley, D.C.4
  • 5
    • 0028341362 scopus 로고
    • Assembly of HLA DR1 molecules translated in vitro: Binding of peptide in the endoplasmic reticulum precludes association with invariant chain
    • Bijlmakers, M.J., P. Benaroch, and H.L. Ploegh. 1994. Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain. EMBO (Eur. Mol. Biol. Organ.) J. 13: 2699-2707.
    • (1994) EMBO (Eur. Mol. Biol. Organ.) J. , vol.13 , pp. 2699-2707
    • Bijlmakers, M.J.1    Benaroch, P.2    Ploegh, H.L.3
  • 6
    • 0028130306 scopus 로고
    • Assembly and peptide binding of major histocompatibility complex class 11 heterodimers in an in vitro translation system
    • Hedley, M.L., R.G. Urban, and J.L. Strominger. 1994. Assembly and peptide binding of major histocompatibility complex class 11 heterodimers in an in vitro translation system. Proc. Natl. Acad. Sci. USA. 91:10479-10483.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10479-10483
    • Hedley, M.L.1    Urban, R.G.2    Strominger, J.L.3
  • 9
    • 0028898253 scopus 로고
    • Allelic differences affecting invariant chain dependency of MHC class II subunit assembly
    • Bikoff, E.K., R.N. Germain, and E.J. Robertson. 1995. Allelic differences affecting invariant chain dependency of MHC class II subunit assembly. Immunity. 2:301-310.
    • (1995) Immunity , vol.2 , pp. 301-310
    • Bikoff, E.K.1    Germain, R.N.2    Robertson, E.J.3
  • 10
    • 0028147578 scopus 로고
    • The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules
    • Elliott, E.A., J.R. Drake, S. Amigorena, J. Elsemore, P. Webster, I. Mellman, and R.A. Flavell. 1994. The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules. J. Exp. Med. 179:681-694.
    • (1994) J. Exp. Med. , vol.179 , pp. 681-694
    • Elliott, E.A.1    Drake, J.R.2    Amigorena, S.3    Elsemore, J.4    Webster, P.5    Mellman, I.6    Flavell, R.A.7
  • 11
    • 0028970194 scopus 로고
    • Transient aggregation of major histocompatibility complex class II chains during assembly in normal spleen cells
    • Marks, M.S., R.N. Germain, and J.S. Bonifacino. 1995. Transient aggregation of major histocompatibility complex class II chains during assembly in normal spleen cells. J. Biol. Chem. 270:10475-10481.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10475-10481
    • Marks, M.S.1    Germain, R.N.2    Bonifacino, J.S.3
  • 12
    • 0028919184 scopus 로고
    • Poor loading of major histocompatibility complex class II molecules with endogenously synthesized short peptides in the absence of invariant chain
    • Busch, R., I.Y. Vturina, J. Drexler, F. Momburg, and G.J. Hammerling. 1995. Poor loading of major histocompatibility complex class II molecules with endogenously synthesized short peptides in the absence of invariant chain. Eur. J. Immunol. 25:48-53.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 48-53
    • Busch, R.1    Vturina, I.Y.2    Drexler, J.3    Momburg, F.4    Hammerling, G.J.5
  • 13
    • 0028136262 scopus 로고
    • The CLIP region of invariant chain plays a critical role in regulating MHC class II folding, transport, and peptide occupancy
    • Romagnoli, P., and R.N. Germain. 1994. The CLIP region of invariant chain plays a critical role in regulating MHC class II folding, transport, and peptide occupancy. J. Exp. Med. 180:1107-1113.
    • (1994) J. Exp. Med. , vol.180 , pp. 1107-1113
    • Romagnoli, P.1    Germain, R.N.2
  • 14
    • 0025826118 scopus 로고
    • MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding
    • Germain, R.N., and L.R. Hendrix. 1991. MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature (Lond.). 353:134-139.
    • (1991) Nature (Lond.) , vol.353 , pp. 134-139
    • Germain, R.N.1    Hendrix, L.R.2
  • 15
    • 0025870669 scopus 로고
    • A role for peptide in determining MHC class II structure
    • Sadegh-Nasseri, S., and R.N. Germain. 1991. A role for peptide in determining MHC class II structure. Nature (Lond.). 353:167-170.
    • (1991) Nature (Lond.) , vol.353 , pp. 167-170
    • Sadegh-Nasseri, S.1    Germain, R.N.2
  • 16
    • 0027941809 scopus 로고
    • MHC class II function preserved by low-affinity peptide interactions preceding stable binding
    • Sadegh-Nasseri, S., L.J. Stern, D.C. Wiley, and R.N. Germain. 1994. MHC class II function preserved by low-affinity peptide interactions preceding stable binding. Nature (Lond.). 370:647-650.
    • (1994) Nature (Lond.) , vol.370 , pp. 647-650
    • Sadegh-Nasseri, S.1    Stern, L.J.2    Wiley, D.C.3    Germain, R.N.4
  • 17
    • 0024362181 scopus 로고
    • Capacity of intact proteins to bind to MHC class II molecules
    • Sette, A., L. Adorini, S.M. Colon, S. Buus, and H.M. Grey. 1989. Capacity of intact proteins to bind to MHC class II molecules. J. Immunol. 143:1265-1267.
    • (1989) J. Immunol. , vol.143 , pp. 1265-1267
    • Sette, A.1    Adorini, L.2    Colon, S.M.3    Buus, S.4    Grey, H.M.5
  • 18
    • 0030052495 scopus 로고    scopus 로고
    • Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum
    • Busch, R., I. Cloutier, R.-P. Sékaly, and G.J. Hämmerling. 1996. Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum. EMBO (Eur. Mol. Biol. Organ.) J. 15:418-428.
    • (1996) EMBO (Eur. Mol. Biol. Organ.) J. , vol.15 , pp. 418-428
    • Busch, R.1    Cloutier, I.2    Sékaly, R.-P.3    Hämmerling, G.J.4
  • 19
    • 0029450142 scopus 로고
    • Binding domain regulation of MHC class II molecule assembly, trafficking, fate, and function
    • Germain, R.N. 1995. Binding domain regulation of MHC class II molecule assembly, trafficking, fate, and function. Semin. Immunol. 7:361-372.
    • (1995) Semin. Immunol. , vol.7 , pp. 361-372
    • Germain, R.N.1
  • 21
    • 0028935078 scopus 로고
    • Cell surface expression of class II MHC proteins bound by a single peptide
    • Ignatowicz, L., G. Winslow, J. Bill, J. Kappler, and P. Marrack. 1995. Cell surface expression of class II MHC proteins bound by a single peptide. J. Immunol. 154:3852-3862.
    • (1995) J. Immunol. , vol.154 , pp. 3852-3862
    • Ignatowicz, L.1    Winslow, G.2    Bill, J.3    Kappler, J.4    Marrack, P.5
  • 22
    • 0023850352 scopus 로고
    • SRα promoter: An efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat
    • Takebe, Y., M. Seiki, J. Fujisawa, P. Hoy, K. Yokota, K. Arai, M. Yoshida, and N. Arai. 1988. SRα promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol. 8:466-472.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 466-472
    • Takebe, Y.1    Seiki, M.2    Fujisawa, J.3    Hoy, P.4    Yokota, K.5    Arai, K.6    Yoshida, M.7    Arai, N.8
  • 24
    • 0027498929 scopus 로고
    • Relationship between invariant chain expression and MHC class II transport into early and late endocytic compartments
    • Romagnoli, P., C. Layet, J. Yewdell, O. Bakke, and R.N. Germain. 1993. Relationship between invariant chain expression and MHC class II transport into early and late endocytic compartments. J. Exp. Med. 177:583-596.
    • (1993) J. Exp. Med. , vol.177 , pp. 583-596
    • Romagnoli, P.1    Layet, C.2    Yewdell, J.3    Bakke, O.4    Germain, R.N.5
  • 25
    • 0026048458 scopus 로고
    • Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex α/β chains
    • Sant, A.J., L.R. Hendrix, J.E. Coligan, W.L. Maloy, and R.N. Germain. 1991. Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex α/β chains. J. Exp. Med. 174:799-808.
    • (1991) J. Exp. Med. , vol.174 , pp. 799-808
    • Sant, A.J.1    Hendrix, L.R.2    Coligan, J.E.3    Maloy, W.L.4    Germain, R.N.5
  • 26
    • 0019786306 scopus 로고
    • A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: Evidence for I region gene duplication
    • Bhattacharya, A., M.E. Dorf, and T.A. Springer. 1981. A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J. Immunol. 127:2488-2495.
    • (1981) J. Immunol. , vol.127 , pp. 2488-2495
    • Bhattacharya, A.1    Dorf, M.E.2    Springer, T.A.3
  • 29
    • 0027303736 scopus 로고
    • Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes selective cell surface expression of occupied molecules
    • Germain, R.N., and A.G. Rinker, Jr. 1993. Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes selective cell surface expression of occupied molecules. Nature (Lond.). 363:725-728.
    • (1993) Nature (Lond.) , vol.363 , pp. 725-728
    • Germain, R.N.1    Rinker Jr., A.G.2
  • 30
    • 0028233838 scopus 로고
    • Production of soluble MHC class II proteins with covalently bound single peptides
    • Kozono, H., J. White, J. Clements, P. Marrack, and J. Kappler. 1994. Production of soluble MHC class II proteins with covalently bound single peptides. Nature (Lond.). 369:151-154.
    • (1994) Nature (Lond.) , vol.369 , pp. 151-154
    • Kozono, H.1    White, J.2    Clements, J.3    Marrack, P.4    Kappler, J.5
  • 31
    • 0028921633 scopus 로고
    • Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II
    • Sette, A., S. Southwood, J. Miller, and E. Appella. 1995. Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II. J. Exp. Med. 181:677-683.
    • (1995) J. Exp. Med. , vol.181 , pp. 677-683
    • Sette, A.1    Southwood, S.2    Miller, J.3    Appella, E.4
  • 32
    • 0026015909 scopus 로고
    • Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex AαAβ dimers from the endoplasmic reticulum/cis-Golgi compartment
    • Layet, C., and R.N. Germain. 1991. Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex AαAβ dimers from the endoplasmic reticulum/cis-Golgi compartment. Proc. Natl. Acad. Sci. USA. 88:2346-2350.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2346-2350
    • Layet, C.1    Germain, R.N.2
  • 33
    • 0027141852 scopus 로고
    • A chaperone with a sweet tooth
    • Hammond, C., and A. Helenius. 1993. A chaperone with a sweet tooth. Curr. Biol. 3:884-886.
    • (1993) Curr. Biol. , vol.3 , pp. 884-886
    • Hammond, C.1    Helenius, A.2
  • 34
    • 0026505030 scopus 로고
    • Irreversible association of peptides with class-II MHC molecules in living cells
    • Lanzavecchia, A., P.A. Reid, and C. Watts. 1992. Irreversible association of peptides with class-II MHC molecules in living cells. Nature (Lond.). 357:249-252.
    • (1992) Nature (Lond.) , vol.357 , pp. 249-252
    • Lanzavecchia, A.1    Reid, P.A.2    Watts, C.3
  • 35
    • 0027475731 scopus 로고
    • Identification of two distinct properties of class II major histocompatibility complex-associated peptides
    • Nelson, C.A., S.J. Petzold, and E.R. Unanue. 1993. Identification of two distinct properties of class II major histocompatibility complex-associated peptides. Proc. Natl. Acad. Sci. USA. 90:1227-1231.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1227-1231
    • Nelson, C.A.1    Petzold, S.J.2    Unanue, E.R.3
  • 36
    • 0026695747 scopus 로고
    • Ligand-dependent secretion of rat retinol-binding protein expressed in HeLa cells
    • Melhus, H., B. Laurent, L. Rask, and P.A. Peterson. 1992. Ligand-dependent secretion of rat retinol-binding protein expressed in HeLa cells. J. Biol. Chem. 267:12036-12041.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12036-12041
    • Melhus, H.1    Laurent, B.2    Rask, L.3    Peterson, P.A.4
  • 37
    • 0024324442 scopus 로고
    • Association of class I major histocompatibility heavy and light chains induced by viral peptides
    • Townsend, A., C. Öhlén, J. Bastin, H.G. Ljunggren, L. Foster, and K. Kärre. 1989. Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature (Lond.). 340:443-448.
    • (1989) Nature (Lond.) , vol.340 , pp. 443-448
    • Townsend, A.1    Öhlén, C.2    Bastin, J.3    Ljunggren, H.G.4    Foster, L.5    Kärre, K.6
  • 39
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading
    • Denzin, L.K., and P. Cresswell. 1995. HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell. 82:155-165.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 40
    • 0029084023 scopus 로고
    • DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide
    • Sherman, M.A., D.A. Weber, and P.E. Jensen. 1995. DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide. Immunity. 3:197-205.
    • (1995) Immunity , vol.3 , pp. 197-205
    • Sherman, M.A.1    Weber, D.A.2    Jensen, P.E.3


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