Sustained effects of a single injection of ethanol on the hypothalamic- pituitary-gonadal axis in the male rat

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 8, 1996, Pages 1368-1374

  Steiner, J C ^a   Halloran, M M ^a   Jabamoni, K ^a   Emanuele, N V ^a,b   Emanuele, M A ^a,b  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b HINES VA HOSPITAL   (United States)

Author keywords

Ethanol; LH; LHRH; Testosterone

Indexed keywords

GONADORELIN; LUTEINIZING HORMONE; TESTOSTERONE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GONADORELIN RELEASE; HYPOPHYSIS GONAD SYSTEM; LUTEINIZING HORMONE RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TESTOSTERONE SYNTHESIS;

ANIMALIA;

EID: 0029844983     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01136.x     Document Type: Article

References (31)

1. Gharib SD, Wierman ME, Shupnik MA, Chin WW: Molecular biology of the pituitary gonadotropins. Endocrine Reviews 11:177-199, 1990
2. Wierman ME, Gharib SD, Chin WW: The structure and regulation of the pituitary gonadotropin subunit genes. Baillieres Clin Endocrinol Metab 2:869-889, 1988
3. Gharib SD, Bowers SM, Need LR, Chin WW: Regulation of rat luteinizing hormone subunit messenger ribonucleic acids by gonadal steroid hormones. J Clin Invest 77:582-589, 1986
4. Neuman I, Solano AR, Paz C, Mele P, Cornejo Maciel F, Lemos JR, Fernandez HN, Podesta EJ: The action of luteinizing hormone on the testis. J Steroid Biochem Mol Biol 40:441-451, 1991
5. Parkarinen P, Proshlyakova E, Huhtaniemi I: Pituitary-gonadal interactions in perinatal rats: Relationships of plasma luteinizing hormone and testosterone concentrations, and pituitary levels of LH subunit mRNAs. Neuroendocrinology 60:42-49, 1994
6. Corbani M, Counis R, Starzec A, Justisz M: Effect of gonadectomy on pituitary levels of mRNA encoding gonadotropin subunits and secretion of luteinizing hormone. Mol Cell Endocrinol 35:83-92, 1984
7. Pakarinen P, Huhtaniemi I: Age-related discrepancies between serum and pituitary gonadotrophin, and pituitary gonadotrophin subunit mRNA responses to castration and testosterone replacement in male rats. J Endocrinol 135:507-515, 1992
8. Emanuele NV, Jurgens J, La Paglia N, Williams DW, Kelley MR: The effect of castration on steady state levels of luteinizing hormone-releasing hormone (LHRH) mRNA and proLHRH processing: Time course study utilizing semi-quantitative reverse transcription/polymerase chain reaction: J Endocrinol 148:509-515, 1996
9. Emanuele MA, Halloran MM, Uddin S, Tentler JJ, Emanuele NV, Lawrence AM, Kelley MR: The effects of alcohol on the neuroendocrine control of reproduction, in Zakhari S (ed): Alcohol and the Endocrine System. Bethesda, MD, National Institutes of Health, 1993, p 89
10. Purohit V: Effects of alcohol on the hypothalamic-pituirary-gonadal axis, in Zakhari S (ed): Alcohol and the Endocrine System. Bethesda, MD, National Institutes of Health, 1993, p 189
11. Ching M, Valenca M, Negro-Vilar A: Acute ethanol treatment lowers hypophyseal portal plasma LHRH and systemic LH levels in orchidectomized rats. Brain Res 443:315-328, 1988
12. Pohl CR, Guilinger RA, Van Thiel DH: Inhibitory action of ethanol on LH secretion of rat anterior pituitary cells in culture. Endocrinology: 120:849-852, 1987
13. Emanuele MA, Tentler J, Emanuele NV, Reda D, Kirsteins L, Lawrence AM: In vitro effect of ethanol exposure on basal and GnRH-stimulated LH secretion from pituitary cells. Endocrine Res 15:383-401, 1989
14. Emanuele MA, Tentler J, Emanuele NV, Kelley MR: In vivo effects of acute EtOH on rat alpha and beta luteinizing hormone gene expression. Alcohol 8:345-348, 1991
15. Cobb CF, Ennis MF, Van Thiel DH, Gavaler JS, Lester R: Acetaldehyde and ethanol are testicular toxins. Gastroenterology 73:958-965, 1978
16. Salonen I, Huhtaniemi I: Effects of chronic ethanol diet on pituitary-testicular function of the rat. Biol Reprod 42:55-62, 1990
17. Chomcyznski P, Sacchi N: Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction, Anal Biochem 162:156-159, 1987
18. Salonen I, Pakarinen P, Huhtaniemi I: Effect of chronic ethanol diet on expression of gonadotropin genes in the male rat. J Pharmacol Exp Ther 260:463-467, 1992
19. Cicero TJ, Meyer ER, Bell RD: Effects of ethanol on the hypothalamic-pituitary-luteinizing hormone axis and testicular steroidogenesis. Pharmacol Exp Ther 208:210-215, 1979
20. Rivier C, Rivest S, Vale W: Alcohol-induced inhibition of LH secretion in intact and gonadectomized male and female rats: Possible mechanisms. Alcohol Clin Exp Res 16:935-941, 1993
21. Gonzalez-Reimers E, Marinez-Riera A, Santolaria-Fernandez F, Conde-Martel A, Alvarez-Arguelles H, Santana-Herrera C, Rodriguez-Moreno F: Relative and combined effects of the ethanol and protein deficiency on gonadal function and histology. Alcohol 11:355-360, 1994
22. Lester R, Van Theil DH: Gonadal function in chronic alcoholic men. Adv Exp Med Biol 85A:399-413, 1977
23. Konstadoulakis MM, Syrigos KN, Baxevanis CN, Syrigou EI, Papamichail M, Peveretos P, Anapliotou M, Golematis BC: Effect of testosterone administration, pre-postnatally, on the immune System of rats, Horm Metab Res 27:275-278, 1995
24. Baillie SP, Davison CE, Johnson FJ, Francis RM: Pathogenesis of vertebral crush fractures in men. Age Ageing 21:139-141, 1992
25. Horowitz M, Wishart JM, O'Loughlin PD, Morris HA, Need AG, Nordin BE: Osteoporosis and Klinefelter's syndrome. Clin Endocrinol 36;113-118, 1992
26. Resch H, Pietschmann P, Woloszczuk W, Krexner E, Bernecker P, Willvonseder R: Bone mass and biochemical parameters of bone metabolism in men with spinal osteoporosis. Eur J Clin Invest 22:542-545, 1992
27. Devogelaer JP, PeCooman S, Nagant de Deuxchaisnes C: Low bone mass in hypogonadal males. Effect of testosterone substitution therapy, a densitometric study. Maturitas 15:17-23, 1992
28. Azad N, Agrawal L, Emanuele MA, Kelley MR, Mohagheghpour N, Lawrence AM, Emanuele NV: Neuroirnmunoendocrinology. Am J Reprod Immunol 26:160-172, 1991
29. Sassa S, Zhang H, Okamoto R: Long-term observation of serum hormone fluctuations in aging model of gonadectomized rat. Folia Endocrinol Jap 70:69-74, 1994
30. Vaubourdolle M, Guechot J, Chazouilleres O, Poupon RE, Giboudeau J: Effect of dihydrotestosterone on the rate of ethanol elimination in healthy men. Alcohol Clin Exp Res 15:238-240, 1991
31. Halloran MM, Emanuele MA, Emanuele NV, Tentler JJ, Kelley MR: Further characterization of the impact of ethanol, on β-LH: Alterations in polyribosome association of β-LH mRNA. Endocrine 3:469-473, 1995