Response of germfree rat colonic mucous cells to peroral endotoxin application

European Journal of Cell Biology

Volumn 71, Issue 1, 1996, Pages 99-104

  Enss, Marie L ^a   Schmidt Wittig, Undine ^a   Müller, Hartmut ^a   Mai, Uwe E H ^a   Coenen, Manfred ^b   Hedrich, Hans J ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Germfree rat; Goblet cell; Lipid A; Lipopolysaccharide; Mucin

Indexed keywords

ENDOTOXIN; LIPID A; LIPOPOLYSACCHARIDE; MUCIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASCENDING COLON; BACTERIAL COLONIZATION; BACTERIAL MEMBRANE; CELL PROLIFERATION; COLON MUCOSA; CONTROLLED STUDY; DESCENDING COLON; GERMFREE ANIMAL; GLYCOPROTEIN SYNTHESIS; GOBLET CELL; HISTOMETRY; INFLAMMATION; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0029844846     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Abrams, G. D., H. Bauer, H. Spitz: Influence of the normal flora on mucosa morphology and cellular renewal in the ileum. A comparison of germ-free and conventional mice. Lab. Invest. 12, 356-364 (1963).
2. Allen, A., N. J. K. Carrol: Adherent and soluble mucus in the stomach and duodenum. Dig. Dis. Sci. 30, 55S-62S (1986).
3. Carlstedt, I., J. K. Sheehan, A. P. Corfield, J. T. Gallagher: Mucous glycoproteins: a gel of problem. Essays Biochem. 20, 40-77 (1985).
4. Chadee, K., K. Keller, J. Forstner, D. J. Innes, J. I. Ravdin: Mucin and nonmucin secretagogue activity of Entamoeba histolytica and cholera toxin in rat colon. Gastroenterology 100, 986-997 (1991).
5. Ciao, M. J., W. J. Ma, L. Ma, R. Berg, R. D. Specian: Endotoxin-induced alterations in rat colonie water and electrolyte transport. Gastroenterology 103, 1437-1443 (1992).
6. Clamp, J. R.: A gas liquid chromatographic approach to the analysis of carbohydrates. Biochem. Soc. Trans. 5, 1693-1695 (1977).
7. Cohan, V. L., A. L. Scott, C. A. Dinarello, R. A. Prendergast: Interleukin-1 is a mucus secretagogue. Cell. Immunol. 136, 425-434 (1991).
8. Deitch, E. A., W. J. Ma, L. Ma, R. Berg, R. D. Specian: Endotoxin-induced baterial translocation: A study of mechanisms. Surgery 106, 292-300 (1989).
9. Diener, M., W. Rummel, E. Scharrer: Regulation des Zellvolumens in isolierten Krypten aus dem Kolon der Ratte. Z. Gastroenterologie (Suppl. 4), 31, 12-14 (1993).
10. Dignass, A. U., D. K. Podolsky: Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor β. Gastroenterology 105, 1323-1332 (1993).
11. Enss, M.-L., U. Schmidt-Wittig, K. Höner, R. Kownatzki, K. Gärtner: Mechanical challenge causes alterations of rat colonie mucosa and released mucins. J. Exp. Anim. Sci. 36, 128-140 (1994).
12. Enss, M.-L., U. Schmidt-Wittig, H. Müller, U. E. H. Mai, H. J. Hedrich: Effects of peroral endotoxin application on colonie mucins in germfree rats. J. Lab. Anim. Sci. 37, 138-148 (1996).
13. Flemming, S. E., M. D. Fitch, S. de Vries: The influence of dietary fiber on proliferation of intestinal mucosal cells in miniature swine may not be mediated primarily by fermentation. J. Nutr. 122, 906-916 (1992).
14. Forstner, G.: Signal transduction, packaging and secretion of mucins. Annu. Rev. Physiol. 57, 585-605 (1995).
15. Goodled, R. A., B. Ratcliffe, J. P. Fordham, N. A. Weight: Does dietary fibre stimulate intestinal epithelial cell proliferation in germfree rats? Gut 30, 820-825 (1989).
16. Gordon, H. A., B. S. Bruckner: Anomalous lower bowel function and related phenomena in germfree animals. In: M. E. Coates, B. E. Gustafsson (eds.): The Germfree Animal in Research. pp. 193-213. Laboratory Animals Ltd. London 1984.
17. Harkema, J. R., J. A. Hotchkiss: In vivo effects of endotoxin on intraepithelial mucosubstances in rat pulmonary airways. Am. J. Pathol. 141, 307-317 (1992).
18. Heneghan, J. B.: Physiology of the alimentary tract. In: M. E. Coates, B. E. Gustafsson (eds.): The Germfree Animal in Biomedical Research. Laboratory Animals Ltd. pp. 169-192. London 1984.
19. Hill, R. R., H. M. Cowley: Alteration in colonie crypt architecture and mucin production following polyassociation of germfree mice with autochtonous crypt-inhabiting bacteria. Microecology and Therapy 19, 356-364 (1989).
20. Hommes, D. W., Y. Zhao, E. Bernart, J. Jansen, S. A. Radema, S. J. H. van Deventer: Endotoxin induced endogenous mediators in the pathogenesis of septicaemia. In: H. Cottier, P. J. Heidt, V. C. Rusch, W. van der Waaij (eds.): Effective and Ineffective Defence Mechanisms in the Gastrointestinal Tract. pp. 78-93. Institute for Microbiology and Biochemistry, Herborn-Dill/Germany 1994.
21. Jacobs, L. R., B. O. Shneeman: Effects of dietary wheat bran on rat colonie structure and mucosal cell growth. J. Nutr. 111, 798-803 (1981).
22. Jacobs, L. R., J. R. Lupton: Effect of dietary fibers on rat large bowel mucosal growth and cell proliferation. Am. J. Physiol. 246, G378-G385 (1984).
23. Kunstyr, I. (ed.): Diagnostic Microbiology for Laboratory Animals. GV-SOLAS. Vol. 11. Gustav Fischer Verlag. Stuttgart, Jena, New York 1992.
24. Kyoi, T., F. Ueda, K. Kimura, M. Yamamoto, K. Kataoke: Development of gap junctions between gastric surface mucous cells during cell maturation in rats. Gastroenterology 103, 1930-1935 (1992).
25. Lesher, B., H. E. Walburg, G. A. Sacher: Generation cycle in the duodenal crypts of germ-free and conventional mice. Nature 202, 884-886 (1964).
26. Loppnow, H., H. Brade, E. T. Rietschel, H.-D. Flad: Induction of cytokines in mononuclear and vascular cells by endotoxin and other bacterial products. In: V. L. Clark, P. M. Bavoil: Bacterial Pathogenesis. Vol. 236. pp. 3-10. Academic Press New York 1994.
27. Mesters, M. D., R. G. Tomkins, J. A. Gelfand, C. A. Dinarello, J. F. Burke, B. D. Clark: Intestinal production of Interleukin-1α during endotoxemia in the mouse. J. Surg. Res. 54, 584-591 (1993).
28. Mowry, R. W., C. H. Winkler: The coloration of acidic carbohydrates of bacteria and fungi in tissue sections with special reference to capsules of Cryptococcus neoformans, Pneumococci, and Staphylococci. Am. J. Pathol. 32, 628-629 (1956).
29. Podolsky, D. K.: Regulation of intestinal epithelial cell proliferation: a few answers, many questions. Am. J. Physiol. 264, G179-G186 (1993).
30. Rietschel, E. T., C. Galanos, O. Luederitz, O. Westphal: Chemical structure, physiological function and biological activity of lipopolysaccharides and their lipid A component. In: R. D. Webb (ed.): Immunopharmacology and the Regulation of Leukocyte Function. pp. 183-229. Marcel Dekker. New York 1982.
31. Specian, R. D., M. G. Oliver: Functional biology of the intestinal goblet cell. Am. J. Physiol. 260, C183-C193 (1991).
32. Sperber, K., S. Ogata, C. Sylvester, J. Aisenberg, A. Chen, L. Mayer, S. Itzkowitz: A novel human macrophage-derived mucin secretagogue: implication for the pathogenesis of inflammatory bowel disease. Gastroenterology 104, 1302-1309 (1993).
33. Strous, G. J., J. Dekker: Mucin-type glycoproteins. Crit. Rev. Biochem. Mol. Biol. 27, 57-92 (1992).
34. Szentkuti, L., H. Riedesel, M.-L. Enss, K. Gärtner, W. von Engelhardt: Pre-epithelial mucus layer in the colon of conventional and germ-free rats. Histochem. J. 22, 124-138 (1992).
35. Tse, K.-S., K. Chadee: The interaction between intestinal mucus glycoproteins and enteric infections. Parasitol. Today 7, 163-172 (1991).
36. Uribe, A., E. Jaramillo, T. Midtvedt: Cell kinetics of the proximal jejunal epithelium in germfree rats. 10th International Symposium on Gnotobiology. p. 100. Leiden/The Netherlands 1990.
37. Walker, R. I., R. L. Owen: Intestinal barriers to bacteria and their toxins. Annu. Rev. Med. 41, 393-400 (1990).
38. Weldon, M. J., J. D. Maxwell: Lymphocyte and macrophage receptors in inflammatory bowel disease: a more selective target for therapy? Gut 35, 867-871 (1994).