Intraplatelet cyclic 3'-5' guanosine monophosphate is related to serum cholesterol

International Angiology

Volumn 15, Issue 3, 1996, Pages 201-206

  Anwaar, I ^a   Gottsater A ^a   Wallmark, A ^a   Hedblad, B ^a   Lindgarde F ^a   Mattiasson, I ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Atherosclerosis; Endothelium; Platelets

Indexed keywords

CHOLESTEROL; CYCLIC GMP; GLUCOSE; GUANYLATE CYCLASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRIC OXIDE; TRIACYLGLYCEROL;

ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE; BODY MASS; CHOLESTEROL BLOOD LEVEL; COMMON CAROTID ARTERY; CORRELATION FUNCTION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INTIMA; MALE; NORMAL HUMAN; RADIOIMMUNOASSAY; RISK ASSESSMENT; RISK FACTOR; SMOKING HABIT; THROMBOCYTE COUNT;

AGE FACTORS; AGED; ANTIHYPERTENSIVE AGENTS; ARTERIOSCLEROSIS; BLOOD GLUCOSE; BLOOD PLATELETS; BLOOD PRESSURE; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CYCLIC GMP; DIABETES MELLITUS; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; MIDDLE AGED; PLATELET COUNT; RADIOIMMUNOASSAY; RISK FACTORS; SMOKING; TRIGLYCERIDES;

EID: 0029844754     PISSN: 03929590     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Ignarro L, Buga G, Wood K, Byrns R, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci 1987;84:9265-9.
2. Palmer R, Ferrige A, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-6.
3. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993;329:2002-12.
4. Ware J, Heistad D. Platelet-endothelium interactions. N Engl J Med 1993;328:628-35.
5. Rapoport R, Draznin M, Murad F. Endothelium dependent relaxation in rat aorta may be mediated through cGMP-dependent protein phosphorylation. Nature 1983;306:174-6.
6. Radomski M, Palmer R, Moncada S. An L-arginine NO pathway present in human platelets regulates aggregation. Proc Natl Acad Sci USA 1990;87:5193-7.
7. Venturini C, Weston L, Kaplan J. Platelet cGMP, but not cAMP, inhibits thrombin-induced platelet adhesion to pulmonary vascular endothelium. Am J Physiol 1992; 263:H606-12.
8. Radomski M, Palmer R, Moncada S. The anti-aggregating properties of vascular endothelium: interaction between prostacyclin and NO. Br J Pharmacol 1987;92:639-46.
9. Watanabe H, Kakihana M, Ohtsuka S, Enomoto T, Yasui K, Sugishita Y. Platelet cyclic GMP. A potentially useful indicator to evaluate the effects of nitroglycerin and nitrate tolerance. Circulation 1993; 88:29-36.
10. Hoffmann G, Göbel B, Harbrecht U, Vetter H, Düsing R. Platelet cAMP and cGMP in essential hypertension. Am J Hypertens 1992;5:847-50.
11. Anderson T, Meredith I, Yeung A, Frei B, Selwyn A, Ganz P. The effects of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion. N Engl J Med 1995;332:488-93.
12. Treasure C, Klein J, Weintraub W et al. Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary disease. N Engl J Med 1995;332:481-7.
13. Berglund G, Elmstahl S, Janzon L, Larsson SA. The Malmö Diet and Cancer Study. Design and feasabiliy. J Int Med 1993;233:45-51.
14. Larsson B, Svärdsudd K, Welin L, Wilhelmsen L, Björntorp P, Tibblin G. Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow-up of participants in the study of men born 1913. Br Med J 1984;288:1401-4.
15. Endre T, Mattiasson, I, Hulthen UL, Lindgärde F, Berglund G. Insulin resistance is coupled to low physical fitness in normotensive men with a family history of hypertension. J Hypertens 1994;12:81-8.
16. Amado J, Poveda J, Salas E, Berrazueta J, Botana M. Low levels of intraplatelet cGMP in IDDM. Diabetes Care 1993;16:809-811.
17. Brooker G, Harper J, Terasaki W, Moylan R. Radioimmunoassay of cyclic AMP and cyclic GMP. In: Brooker G, Greengard P, Robison G, editors. Advances in cyclic nucleotide research. New York: Raven Press, 1979;10:1-32.
18. Jeppsson J-O, Jerntorp P, Sundkvist G, Englund H, Nylund V. Measurement of hemoglobin A1c by a new lipid-chromatographic assay: Methodology, clinical utility, and relation to glucose tolerance evaluated. Clin Chem 1986;32:1867-72.
19. Burstein M, Scholnik H, Morfin R. Rapid method for the isolation of proteins from human serum by precipitation with polyanions. J Lipid Res 1970;11:583-95.
20. Wendelhag I, Gustavsson T, Suurküla M, Berglund G, Wikstrand J. Ultrasound measurement of wall thickness in the carotid artery. Fundamental principles and description of a computerized analysing system. Clin Phys 1991;11:565-77.
21. Persson J, Stawenov L, Wikstrand J, Istraelsson B, Formgren J, Berglund G. Noninvasive quantification of atherosclerotic lesions. Reproducibility of ultrasonographic measurements of arterial wall thickness and plaque size. Arterioscler Thromb 1993;13:482-6.
22. Persson J, Formgren J, Israelsson B, Berglund G. Ultrasound determined intima media thickness and atherosclerosis. Direct and indirect validation. Arterioscler Thromb 1994;14:261-4.
23. Karpatkin S. Heterogenity of human platelets VI. Correlation of Platelet function with platelet volume. Blood 1978;51(2):307-16.