Hepatic 5-aminoIevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins

European Journal of Biochemistry

Volumn 240, Issue 1, 1996, Pages 112-117

  Bonkovsky, Herbert L ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

5 aminolevulinate acid synthase; Heme; Heme oxygenase; mRNA stability; Zinc mesoporphyrin

Indexed keywords

4,6 DIXOHEPTANOIC ACID; 5 AMINOLEVULINATE SYNTHASE; DEFEROXAMINE; HEME; HEME OXYGENASE; MESSENGER RNA; METALLOPORPHYRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; LIVER CELL; NONHUMAN; PRIORITY JOURNAL;

5-AMINOLEVULINATE SYNTHETASE; ALLYLISOPROPYLACETAMIDE; ANIMALS; CELLS, CULTURED; CHICK EMBRYO; DACTINOMYCIN; DEFEROXAMINE; ENZYME INHIBITORS; GLUTETHIMIDE; HEME; HEPTANOATES; KINETICS; LIVER; METALLOPORPHYRINS; PORPHOBILINOGEN SYNTHASE; REGRESSION ANALYSIS; RNA, MESSENGER;

EID: 0029844702     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0112h.x     Document Type: Article

References (3)

1. Kappas, A., Sassa, S., Galbraith, R. A. & Nordmann, Y. (1989) The porphyrias, in The metabolic basis of inherited disease (Scriver, C. R., Beaudet, A. L., Sly, W. S. & Valle, D., eds) 6th edn, pp. 1305-1365, McGraw-Hill, Inc., New York, NY.
2. Bonkovsky, H. L. (1990) Porphyrin and heme metabolism and the porphyrias, in Hepatology a textbook of liver disease (Zakim, D. & Boyer, T. D., eds) pp. 378-424, W. B. Saunders Company, Philadelphia.
3. Bonkovsky, H. L. (1993) Advances in understanding and treating 'the little imitator', acute porphyria, Gastroenterology 105, 590-594.