Evidence for apoptosis of human macrophage-like HL-60 cells by Legionella pneumophila infection

Infection and Immunity

Volumn 64, Issue 12, 1996, Pages 4900-4906

  Müller, Anne ^a,b   Hacker, Jörg ^a   Brand, Bettina C ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Max Planck Insitut F I   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; ARTICLE; BACTERIAL GROWTH; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; MACROPHAGE; PRIORITY JOURNAL;

EID: 0029844198     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.12.4900-4906.1996     Document Type: Article

References (42)

1. Arends, M. J., and A. H. Wyllie. 1991. Apoptosis: mechanisms and roles in pathology. Int. Rev. Exp. Pathol. 32:223-254.
2. 21 and pH. Biochem. Biophys. Res. Commun. 186:782-789.
3. Blander, S. J., and M. A. Horwitz. 1989. Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. J. Exp. Med. 169: 691-705.
4. Chen, Y., and A. Zychlinsky. 1994. Apoptosis induced by bacterial pathogens. Microb. Pathog. 17:203-212.
5. Clanciotto, N. P., B. I. Eisenstein, C. H. Mody, and N. C. Engleberg. 1990. A mutiuion in the mip gene results in an attenuation of Legionclla pneumophila virulence. J. Infect. Dis. 162:121-126.
6. Clanciotto, N. P., B. I. Eisenstein, C. H. Mody, G. B. Toms, and N. C. Engleberg. 1980. A Legionella pneumophila gene encoding a spccies-specific surface protein potentiates initiation of intruccllular infection. Infect. Immun. 57:1255-1262.
7. Cianciotto, N. P., and B. S. Fields, 1992 Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages. Proc. Natl. Acad. Sci. USA 89:5188-5191.
8. Clemens, D. L. 1996. Characterization of the Mycobacterium tuberculosis phagosome. Trends Microbiol. 4:113-118.
9. Cohen, J. J. 1993. Apoptosis. Immunol. Today 14:l26-l28.
10. Collins, S. J., F. W. Ruscetti, K. E. Gallagher, and R. C. Gallo. l978. Terminal differentiation of human promyelocytic leukemia colls induced by dimethyl sulfoxidc and other polar compounds. Proc. Natl Acad. Sci. USA 75:2458-2462.
11. Ellis, R. E., J. Yuan, and H. R. Horvitz. 1991. Mechanisms and functions of cell death. Annu. Rev. Cell Biol. 7:663-698.
12. Engleberg, N. C., E. Pearlman, and B. I. Eisenstein, 1989. DNA sequence of mip. a Legianella pneumophila gene associated with macrophage infectivity. Infect. Immun. 57:1263-1270.
13. Feeley, J. C., R. J. Gibson, G. W. Gorman, N. C. Langford, J. K. Rasheed, D. C. Mackel, and W. B. Baine. 1979. Charcoal-yeast extract agar: primary isolation medium for Legionella pneumophila. J. Clin. Microbiol. 10:437-441.
14. Fischer, G., H. Bang, B. Ludwig, K. Mann, and J. Hacker. 1992. Mip protein of Legionella pneumophila exhibits peptidyl-prolyl cis/trans isomcrase (PPIase) activity. Mol. Microbiol. 6:1375-1383.
15. Friedman, R. L., B. H. Iglewski, and R. D. Miller. 1980. Identification of a cytotoxin produced by Legionella pneumophila. Infect. Immun. 29:271-274.
16. A. Gavriell, Y., Y. Sherman, and S. A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
17. Guzman, C. A., E. Domann, M. Rohde, D. Bruder, A. Darji, S. Weiss, J. Wehland, T. Chakraborty, and K. N. Timmis. 1996. Apoptosis of mouse dendritic cells is triggered by listeriolysin, the major virulence determinant of L. monocytogenes. Mol. Microbiol. 20:119-126.
18. Hacker, j., and G. Fischer. 1993. Immunophilins: structure-function relationship and possible role in pathogenicity. Mol. Microbiol. 11:445-456.
19. Horwitz, M. A. 1983. The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosomc-lysosomc fusion in human monocytes. J. Exp. Med. 158:1319-1331.
20. Horwitz, M. A. 1984. Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment with a pseudopod coil. Cell 36:27-33.
21. Horwitz, M. A., and F. R. Maxfield. 1984. Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J. Cell Biol. 99:105-114.
22. Horwitz, M. A., and S. C. Silverstein. 1980. Legionnaires' disease bacterium (Legionella pneumophila) multiplies intracellularly in human monocyles. J. Clin. Invest. 66:441-550.
23. Husmann, L. K., and W. Johnson. 1994. Cytotoxicity of extracellular Legionella pneumophila. Infect. Immun. 62:2111-2114.
24. Jepras, R. I., R. B. Fitzgeorge, and A. Baskerville. 1985. A comparison of virulence of two strains of Legionella pneumophila based on experimental aerosol infection of guinea-pigs. J. Hyg. 95:29-38.
25. Kato, S., M. Muro, S. Akifusa, N. Hanada, I. Semba, T. Fujii, Y. Kowashi, and T. Nishihara. 1995. Evidence for apoptosis of murine macrophages by Actinobacillus actinomycetemcomitans infection. Infect. Immun. 63:3914-1919.
26. Keen, M. G., and P. S. Hoffman. 1989. Characterization of a Legionella pneumophila extracellular protease exhibiting hemolytic and cytotoxic activities. Infect. Immun. 57:732-738.
27. Khelef, N., A. Zychlinski, and N. Guise. 1993. Bordetella pertussis induces apoptosis in macrophages: role of adenylate cyclase-hemolysin. Infect. Immun. 61:4064-4071.
28. Marra, A., M. A. Horwitz, and H. A. Shuman. 1990. The HL-60 model for the interaction of human macrophages with the Legionnaires' disease bacterium. J. Immunol. 144:2738-2744.
29. Marra, A., and H. A. Shuman. 1989. Isolation of a Legionella pneumophila restriction mutant with increased ability to act as a recipient in heterospecific matings. J. Bacteriol. 171:2238-2240.
30. Martin, S. J., and D. R. Green. 1995. Proteasc activation during apoptosis: death by a thousand cuts. Cell 82:344-352.
31. Martin, S. J., S. V. Lennon, A. M. Bonham, and T. G. Cotter. 1990. Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. J. Immunnl 145:1859-1867.
32. Molloy, A., P. Laochumroonvorapong, and G. Kaplan. 1994. Apoptosis, but not necrosis of infected monocytes is coupled with killing of intracellular BCG. J. Exp. Med. 180:1499-1509.
33. Pearlman, E., A. H. Jlwa, N. C. Engleberg, and B. I. Eisenstein. 1988. Growth of Legionella pneumophila in a human macrophage-like (U937) cell line. Microb. Pathog. 5:87-95.
34. Quinn, F. D., M. G. Keen, and L. S. Tompkins. 1989. Genetic, immunological and cytotoxic comparison of Legionello proteolytic activities. Infect. Immun. 57:2719-2725.
35. Quinn, F. D., and L. S. Tompkins. 1989. Analysis of a cloned sequence of Legionella pneumophila encoding a 38 kD metalloprotease possessing hemolytic and cytotoxic activities. Mol. Microbiol. 3:797-805.
36. Raff, M. C. 1992. Social controls on cell survival and cell death. Nature (London) 356:397-400.
37. Sadosky, A. B., L. A. Wiater, and H. A. Shuman. 1993. Identification of Legionella pneumophila genes required for growth within and killing of human macrophages, Infect. Immun. 61:5361-5373.
38. Szeto, L., and H. A. Shuman. 1990. The Legionella pneumophila major secretory protein, a protease, is not required for intrucellular growth or cell killing. Infect. Immun. 58:2585-2592.
39. Wiater, L. A., A. B. Sadosky, and H. A. Shuman, 1994. Mutagenesis of Legionella pneumophila using Tn903dIIlacZ: identification of a growth-phase-regulated pigmentation gene. Mol. Microbiol. 11:641-653.
40. Williams, G. T. 1994. Programmed cell death: a fundamental protective response to pathogens. Trends Microbiol. 2:463-464.
41. Wintermeyer, E., B. Ludwig, M. Steinert, B. Schmidt, G. Fischer, and J. Hacker. 1995. Influence of site specific altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells. Infect. Immun. 63: 4576-4583.
42. Zyehlinsky, A., M. C. Prevost, and P. J. Sansonetti. 1992. Shigella flemeri induces apoptosis in infected macrophages. Nature (London) 358:167-169.