Gold replacement of cadmium, zinc-binding metallothionein

Research Communications in Molecular Pathology and Pharmacology

Volumn 93, Issue 1, 1996, Pages 101-107

  Saito, Shigeru ^a   Kurasaki, Masaaki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; GOLD; METALLOTHIONEIN; ZINC;

ARTICLE; BINDING AFFINITY; ENZYME BINDING; METAL BINDING; PRIORITY JOURNAL; ULTRAVIOLET SPECTROSCOPY;

CADMIUM; GOLD; METALLOTHIONEIN; PROTEIN BINDING; SPECTROPHOTOMETRY, ULTRAVIOLET; ZINC;

EID: 0029843778     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Block, W.D.,Buchanan, O.H.,and Freyberg, R.H. (1941) Metabolism, toxicity and manner of action of gold compounds used in the treatment of arthritis. J. Pharm. Exp. Ther. 73, 200-204.
2. Gottlieb, N.L.,Smith, P.M.,and Smith, E.M. (1972) Tissue gold concentrations in a rheumatoid arthritic receiving chrysotherapy. Arthritis Rheum. 15, 16-22.
3. Kägi, J.H.R. (1993) In: Metallothionein III: Biological roles and medical implications. Edited by Suzuki, K.T., Imura, N. and Kimura, M. Birkhäuser Verlag Basel, Switzerland, pp. 29-55.
4. Kägi, J.H.R.,and Schäffer, A. (1988) Biochemistry of metallothionein. Biochemistry 27, 8509-8515.
5. Kägi, J.H.R.,and Vallee, B.L. (1961) Metallothionein: a cadmium and zinc-containing protein from equine renal cortex. II. Physicochemical properties. J. Biol. Chem. 236, 2435-2442.
6. Margoshes, M.,and Vallee, B.L. (1957) A cadmium protein from equine kidney cortex. J. Amer. Chem. Soc. 79, 4813-4814.
7. McQueen, E.G.,and Dykes, P.W. (1969) Transport of gold in the body. Ann. Rheum. Dis. 28, 437-442.
8. Mogilnicka, E.,and Webb, M. (1982) The effects of cadmium and copper on the renal uptake and metallothionein binding of gold in the rat and hamster. Chem. Biol. Interact. 40, 247-256.
9. Nielson, K.B.,Atkin, C.L.,and Winge, D.R. (1985) Distinct metal-binding configurations in metallothionein. J. Biol. Chem. 260, 5342-5350.
10. Saito, S. (1996) The effect of gold on copper and zinc in kidney and in metallothionein. Res. Commun. Molec. Pathol. Pharmacol. (in press).
11. Saito, S.,and Kojima Y. (1996) Relative gold-binding capacity of metallothionein: Studies in renal cytosols from gold-injected rats. Res. Commun. Molec. Pathol. Pharmacol. 92, 119-126.
12. Schmitz, G.,Minkel, D.T.,Gingrich, D.,Shaw, C.F.III. (1980) The binding of gold (I) to metallothionein. J. Inorg. Biochem. 12, 293-306.
13. Sharma, R.P.,and McQueen, E.G. (1980) The binding of gold to cytosolic proteins in the rat liver and kidney tissues: metallothionein. Biochem. Pharmacol. 29, 2017-2021.
14. Sharma, R.P.,and McQueen, E.G. (1981) Effects of gold sodium thiomalate on cytosolic copper and zinc in the rat kidney and liver tissues. Clin. Exp. Pharmacol. Physiol. 8, 591-599.
15. Vasak, M.,Kägi, J.H.R.,and Hill, H.A.O. (1981) Zinc (II), cadmium (II), and mercury (II) thiolate transitions in metallothionein. Biochemistry 20, 2852-2856.
16. Zvaifler, N.J. (1979) Gold and antimalarial therapy. In: Arthritis and Allied Conditions Edited by: D.J. McCarty. Lea and Febiger, Philadelphia.