Interleukin-6 and granulocyte colony-stimulating factor synergistically increase peripheral blood progenitor cells in myelosuppressive mice

Japanese Journal of Cancer Research

Volumn 87, Issue 9, 1996, Pages 938-944

  Suzuki, Hideki ^a   Okano, Akira ^a   Ejima, Chieko ^a   Konishi, Atsushi ^a   Akiyama, Yukio ^a   Ozawa, Keiya ^b,c   Asano, Shigetaka ^b  

^a AJINOMOTO CO INC   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Autologous PBSCT; CFU GM; G CSF; IL 6; Myelosuppressive mice

Indexed keywords

CARBOPLATIN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 6; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOTRANSPLANTATION; BLOOD CELL COUNT; BONE MARROW; BONE MARROW SUPPRESSION; CELL TRANSPLANTATION; COLONY FORMING UNIT; COLONY FORMING UNIT GM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SPLEEN; STEM CELL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029843632     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1996.tb02123.x     Document Type: Article

References (30)

1. Bensinger, W., Singer, J., Appelbaum, F., Lilleby, K., Longin, K., Rowley, S., Clarke, E., Clift, R., Hansen, J., Shields, T., Storb, R., Weaver, C., Weiden, P. and Buckner, C. D. Autologous transplantation with peripheral blood mononuclear cells collected after administration of recombinant granulocyte stimulating factor. Blood, 81, 3158-3163 (1993).
2. Kawano, Y., Takaue, Y., Watanabe, T., Saito, S., Abe, T., Hirao, A., Sato, J., Ninomiya, T., Suzue, T., Koyama, T., Shimokawa, T., Yokobayashi, A., Asano, S., Masaoka, T., Takaku, F. and Kuroda, Y. Effects of progenitor cell dose and preleukapheresis use of human recombinant granulocyte colony-stimulating factor on the recovery of hematopoiesis after blood stem cell autografting in children. Exp. Hematol., 21, 103-108 (1993).
3. Hohaus, S., Goldschmidt, H., Ehrhardt, R. and Haas, R. Successful autografting following myeloablative conditioning therapy with blood stem cells mobilized by chemotherapy plus rhG-CSF. Exp. Hematol., 21, 508-514 (1993).
4. Stoppa, A. M., Blaise, D., Viens, P., Baume, D., Mannoni, P., Novakovitch, G., David, F. A., Yver, A. and Maraninchi, D. Phase I study of in vivo lenograstim (rHuG-CSF) for stem cell collection demonstrates improved neutrophil recovery after autologous bone marrow transplantation. Bone Marrow Transplant., 13, 541-547 (1994).
5. Shea, T. C., Mason, J. R., Storniolo, A. M., Bissent, E., Breslin, M., Mullen, M. and Taetle, R. High-dose carboplatin chemotherapy with GM-CSF and peripheral blood progenitor cell support: a model for delivering repeated cycles of dose-intensive therapy. Cancer Treat. Rev., 19 (Suppl. C), 11-20 (1993).
6. Suzuki, H., Okano, A., Suzuki, C., Konishi, A., Akiyama, Y., Ishibashi, T., Ozawa, K. and Asano, S. A synergistic increase in transplantable peripheral blood stem cells in mice by co-administration of recombinant human interleukin 6 and recombinant human granulocyte colony-stimulating factor. Transplantation, 59, 1596-1600 (1995).
7. Yasueda, H., Nagase, K., Hosoda, A., Akiyama, Y. and Yamada, K. High-level direct expression of semi-synthetic human interleukin-6 of Escherichia coli and production of N-terminus Met-free product. Biotechnology, 8, 1036-1040 (1990).
8. Takatsuki, F., Okano, A., Suzuki, C., Miyasaka, Y., Hirano, T., Kishimoto, T., Ejima, D. and Akiyama, Y. Interleukin 6 perfusion stimulates reconstitution of the immune and hematopoietic systems after 5-fluorouracil treatment. Cancer Res., 50, 2885-2890 (1990).
9. Hattori, K., Shimizu, K., Takahashi, M., Tamura, M., Oheda, M., Ohsawa, N. and Ono, M. Quantitative in vivo assay of human granulocyte colony-stimulating factor using cyclophosphamide-induced neutropenic mice. Blood, 75, 1228-1233 (1990).
10. Okano, A., Suzuki, C., Takatsuki, F., Akiyama, Y., Koike, K., Ozawa, K., Hirano, T., Kishimoto, T., Nakahata, T. and Asano, S. In vitro expansion of the murine pluripotent hemopoietic stem cell population in response to interleukin 3 and interleukin 6. Transplantation, 48, 495-498 (1989).
11. Kimura, F., Kakemura, Y., Ohtsuki, T., Mizukami, H., Takagi, S., Yamamoto, K., Nagata, N. and Motoyoshi, K. Serial changes of the serum macrophage colony-stimulating factor level after cytoreductive chemotherapy. Int. J. Hematol., 55, 147-155 (1992).
12. Kawano, Y., Takaue, Y., Saito, S., Sato, J., Shimizu, T., Suzue, T., Hirao, A., Okamoto, Y., Abe, T., Watanabe, T., Kuroda, Y., Kimura, F., Motoyoshi, K. and Asano, S. Granulocyte colony-stimulating factor (CSF), macrophage-CSF, granulocyte-macrophage CSF, interleukin-3, and interleukin-6 levels in sera from children undergoing blood stem cell autografts. Blood, 81, 856-860 (1993).
13. Haas, R., Gericke, G., Witt, B., Cayeux, S. and Hunstein, W. Increased serum levels of granulocyte colony-stimulating factor after autologous bone marrow or blood stem cell transplantation. Exp. Hematol., 21, 109-113 (1993).
14. Miksits, K., Beyer, J. and Siegert, W. Serum concentrations of G-CSF during high-dose chemotherapy with autologous stem cell rescue. Bone Marrow Transplant., 11, 375-377 (1993).
15. Fibbe, W. E., Hamilton, M. S., Laterveer, L. L., Kibbelaar, R. E., Falkenburg, J. H., Visser, J. W. and Willemze, R. Sustained engraftment of mice transplanted with IL-1-primed blood-derived stem cells. J. Immunol., 148, 417-421 (1992).
16. Schaafsma, M. R., Fibbe W. E., van der Harst, D., Duinkerken, N., Brand, A., Osanto, S., Franks, C. R., Willemze, R. and Falkenburg, J. H. Increased numbers of circulating haematopoietic progenitor cells after treatment with high-dose interleukin-2 in cancer patients. Br. J. Haematol., 76, 180-185 (1990).
17. Brugger, W., Bross, K., Frish, J., Dern, P., Weber, B., Mertelsmann, R. and Kantz, L. Mobilization of peripheral blood progenitor cells by sequential administration of interleukin-3 and granulocyte-macrophage colony-stimulating factor following polychemotherapy with etoposide, ifosfamide, and cisplatin. Blood, 79, 1193-1200 (1992).
18. Guillaume, T., D'Hondt, V. and Symann, M. IL-3 and peripheral blood stem cell harvesting. Stem Cells, 11, 173-181 (1993).
19. Ohi, S., Sakamaki, S., Matsunaga, T., Kuga, T., Hirayama, Y., Kohgo, Y. and Niitsu, Y. Co-administration of IL-3 with G-CSF increases the CFU-S mobilization into peripheral blood. Int. J. Hematol., 62, 75-82 (1995).
20. Grzegorzewski, K., Komschlies, K. L., Mori, M., Kaneda, K., Usui, N., Faltynek, C. R., Keller, J. R., Ruscetti, F. W. and Wiltrout, R. H. Administration of recombinant human interleukin-7 to mice induces the exportation of myeloid progenitor cells from the bone marrow to peripheral sites. Blood, 83, 377-385 (1994).
21. Laterveer, L., Lindley, I. J., Hamilton, M. S., Willemze, R. and Fibbe, W. E. Interleukin-8 induces rapid mobilization of hematopoietic stem cells with radioprotective capacity and long-term myelolymphoid repopulating ability. Blood, 85, 2269-2275 (1995).
22. Hastings, R., Kaviani, M. D., Schlerman, F., Hitz, S., Bree, A. and Goldman, S. J. Mobilization of hematopoietic progenitors by rhIL-11 and rhG-CSF in non-human primates. Blood, 84 (Suppl. 1), 23a (1994).
23. Jackson, J. D., Yan, Y., Brunda, M. J., Kelsey, L. S. and Talmadge, J. E. Interleukin-12 enhances peripheral hematopoiesis in vivo. Blood, 85, 2371-2376 (1995).
24. Elias, A. D., Ayash, L., Anderson, K. C., Hunt, M., Wheeler, C., Schwartz, G., Tepler, I., Mazanet, R., Lynch, C., Pap, S., Pelaez, J., Reich, E., Critchlow, J., Demetri, G., Bibbo, J., Schnipper, L., Griffin, J. D., Frei III, E. and Antman, K. H. Mobilization of peripheral blood progenitor cells by chemotherapy and granulocyte-macrophage colony-stimulating factor for hematologic support after high-dose intensification for breast cancer. Blood, 79, 3036-3044 (1992).
25. Peters, W. P., Rosner, G., Ross, M., Vredenburgh, J., Meisenberg, B., Gilbert, C. and Kurtzberg, J. Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. Blood, 81, 1709-1719 (1993).
26. Bishop, M. R., Anderson, J. R., Jackson, J. D., Bierman, P. J., Reed, E. C., Vose, J. M., Armitage, J. O., Warkentin, P. I. and Kessinger, A. High-dose therapy and peripheral blood progenitor cell transplantation: effects of recombinant human granulocyte-macrophage colony-stimulating factor on the autograft. Blood, 83, 610-616 (1994).
27. Lane, T. A., Law, P., Maruyama, M., Young, D., Burgess, J., Mullen, M., Mealiffe, M., Terstappen, L. W., Hardwick, A., Moubayed, M., Oldham, F., Corringham, R. E. T. and Ho, A. D. Harvesting and enrichment of hematopoietic progenitor cells mobilized into the peripheral blood of normal donors by granulocyte-macrophage colony-stimulating factor (GM-CSF) or G-CSF: potential role in allogeneic marrow transplantation. Blood, 85, 275-282 (1995).
28. Andrews, R. G., Briddell, R. A., Knitter, G. H., Rowley, S. D., Appelbaum, F. R. and McNiece, I. K. Rapid engraftment by peripheral blood progenitor cells mobilized by recombinant human stem cell factor and recombinant human granulocyte colony-stimulating factor in nonhuman primates. Blood, 85, 15-20 (1995).
29. Yan, X. Q., Hartley, C., McElroy, P., Chang, A., McCrea, C. and McNiece, I. Peripheral blood progenitor cells mobilized by recombinant human granulocyte colony-stimulating factor plus recombinant rat stem cell factor contain long-term engrafting cells capable of cellular proliferation for more than two years as shown by serial transplantation in mice. Blood, 85, 2303-2307 (1995).
30. Brasel, K., McKenna, H. J., Charrier, K., Morrissey, P., Williams, D. E. and Lyman, S. D. Mobilization of peripheral blood progenitor cells with Flt3 ligand. Blood, 86 (Suppl. 1), 463a (1995).