A source of glycosylated human T-cell lymphotropic virus type 1 envelope protein: Expression of gp46 by the vaccinia virus/T7 polymerase system

Journal of Virology

Volumn 70, Issue 11, 1996, Pages 7349-7359

  Arp, J ^a,b   Levatte, M ^a   Rowe, J ^c   Perkins, S ^c   King, E ^a,b   Leystra Lantz, C ^a,b   Foung, S K H ^c   Dekaban, G A ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPEPTIDASE; N ACETYL BETA GLUCOSAMINIDASE; RECOMBINANT PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS ENZYME; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ARTICLE; CHIMPANZEE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS 2; HUMAN T CELL LEUKEMIA VIRUS INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN GLYCOSYLATION; PROTEIN STABILITY; RETROVIRUS; SPASTIC PARESIS; SPINAL CORD DISEASE; T CELL LEUKEMIA; T CELL LYMPHOMA; VACCINE PRODUCTION; VACCINIA VIRUS; VIRUS ENVELOPE;

EID: 0029843587     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.11.7349-7359.1996     Document Type: Article

References (75)

1. Arp, J., and G. Dekaban. Unpublished data.
2. Arp, J., C. Ford, T. Palker, E. King, and C. Dekaban. 1993. Expression and immunogenicity of the entire human T-cell leukaemia virus type I envelope protein produced in a bacukvirus system. J. Gen. Virol. 74:211-222.
3. Bruck, C., N. Rcsonnet, D. Portelle, Y. Cleuther, M. Mammerickx, A. Burny, R. Mamoun, B. Guillemain, M. van der Maaten, and J. Ghysdael. 1984. Biologically active epitopes of bovine leukaemia virus glycoprotein gp51: their dependence on protein glycosylation and genetic variability. Virology 136:20-31.
4. Bukner, C., C. Roberts, S. Foung, J. Lipka, G. Reyes, K. Hadlock, L. Chan, R. Gongora-Biachi, B. Hjelle, and R. Lal. 1992. Immune responsiveness to the immunodominant recombinant envelope epitopes of human T lymphotropic virus types I and II in diverse geographic populations. J. Infect. Dis. 166:1160-1163.
5. Chen, Y., T. Lee, K. Samuel, A. Okayama, N. Tachibana, I. Mijoshi, T. Papas, and M. Essex. 1989. Antibody reactivity to different regions of human T-cell leukemia virus type I gp61 in infected people. J. Virol. 63:4952-4957.
6. Dales, S., and L. Siminovitch. 1961. The development of vaccinia virus in Earle's L strain cells as examined by electron microscopy. J. Biophys. Biochem. Cytol. 10:475-503.
7. De, B., M. Lairmore, K. Griffis, L. Williams, F. Villinger, T. Quinn, C. Brown, Nzilambi, M. Sugimuto, S. Araki, and T. Folks. 1991. Comparative analysis of nucleotide sequences of the partial envelope gene (5′ domain) among human T-lymphotropic virus type I (HTLV-I) isolates. Virology 182: 413-419.
8. De Thé, G., and R. Bomford. 1993. An HTLV-I vaccine: why. how and for whom? AIDS Res. Hum. Retroviruses 9:381-386.
9. Edouard, E., E. Legrand, T. Astier-Gin, R. Dalibart, S. Geoffre, P. Dalbon, B. Guillemain, and D. Londos-Gagliardi. 1994. Characterization of monoclonal antibodies directed against the gp46 of human T-cell leukemia virus type I. Leukemia Apr. Suppl. 1:S60-S64.
10. Elroy-Stein, O., T. Fuerst, and B. Moss. 1989. Cap-independent translation of mRNA conferred by encephalomyocarditis virus 5′ sequence improves the performance of the vaccinia virus/bacteriophage T7 hybrid expression system. Proc. Natl. Acad, Sci. USA 86:6126-6130.
11. Fenouillet, E., and J.-C. Gluckman. 1991. Effect of a glucosidase inhibitor on the bioactivity and immunoreactivity of human immunodeficiency virus type 1 envelope glycoprotein. J. Gen. Virol. 72:1919-1926.
12. Ford, C., J. Arp, E. King, G. Dekaban, and T. Palker. 1991. Expression and immunogenicity of HTLV-I envelope proteins by recombinant vaccinia virus, p. 253-258. In R. M. Chanock et al. (ed.), Vaccines 91: modern approaches to new vaccines. Cold Spring Harbor Laboratory, Cold Spring Harbor, N. Y.
13. Ford, C., J. Arp, T. Palker, E. King, and G. Dekaban. 1992. Characterization of the antibody response to three different versions of the HTLV-I envelope protein expressed by recombinant vaccinia viruses: induction of neutralizing antibody. Virology 191:448-453.
14. Foung, S., and S. Perkins. 1989. Electric field-induced cell fusion and human monoclonal antibodies. J. Immunol. Methods 116:117-122.
15. Fuerst, T., P. Earl, and B. Moss. 1987. Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes. Mol. Cell. Biol. 7:2538-2544.
16. Geyer, H., D. Holschbach, G. Hunsmann, and J. Schneider. 1988. Carbohydrates of human immunodeficiency virus: structures of oligosaccharides linked to the envelope glycoprotein 120. J. Biol. Chem. 263:11760-11767.
17. Giri, A., P. Markliam. L. Digilio, G. Hurteau, R. Gallo, and G. Franchini. 1994. Isolation of a novel simian T-cell lymphotropic virus from Pan paniscus that is distantly related to the human T-cell leukemia/lymphotropic virus types I and II. J. Virol. 68:8392-8395.
18. Goubau, P., H. Liu, G. DeLange, A. Vandamme, and J. Desmyter. 1993. HTLV-II seroprevalenee in pygmies across Africa since 1970. AIDS Res. Hum. Retroviruses 9:709-713.
19. Hadlock, K., C. Goh, P. Bradshaw, S. Perkins, J. Lo, J. Kaplan, R. Khabbaz, and S. Foung. 1995. Delineation of an immunodominant and HTLV-specific epitope within the HTLV-I transmembrane glycoprotein. Blood 86:1392-1399.
20. Haigwood, N., C. Barker, K. Higgins, P. Skiles, G. Moore, K. Mann, D. Lee, J. Eichberg, and K. Steimer. 1990. Evidence for neutralizing antibodies directed againsl conformational epitopes of HIV-1 gp120, p. 313-320. In R. Chanock et al. (ed.), Vaccines 91: modern approaches to new vaccines. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
21. Haigwood, N., P. Nara, E. Brooks, G. van Nest, G. Ott, K. Higgins, N. Dunlop, C. Scandella, J. Eichberg, and K. Steimer. 1992. Native hut not denatured recombinant human immunodeficiency virus type 1 gp120 generates broad-spectrum neutralization antibodies in baboons. J. Virol. 66:172-182.
22. Hayden, D., N. Baker, M. Percival, and P. Beckwith. 1986. Modification of the photosystem II light-harvesting chlorophyll a/b protein complex in maize during chill-induced photoinhibition. Biochim. Biophys. Acta 851:86-92.
23. Ho, D., M. Fung, Y. Cao, X. Li, C. Sun, T. Chang, and N.-C. Sun. 1991. Another discontinuous epitope on gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibody. Proc. Natl. Acad. Sci. USA 88:8949-8952.
24. Ho, D., J. McKeating, X. Li, T. Moudgil, E. Daar, N.-C. Sun, and J. Robinson. 1991. Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody. J. Virol. 65:489-493.
25. Ijichi, S., T. Matsuda, I. Maruyama, T. Izumihara, K. Kojima, T. Niimura, Y. Maruyama, S. Sonoda, A. Yoshida, and M. Osame. 1990. Arthritis in a human T lymphotropic virus type (HTLV-I) carrier. Ann. Rheum. Dis. 49:718-721.
26. Johnson, D., J. Gautsch, J. Sportsman, and J. Elder. 1984 Improved technique utilizing nonfat dry milk for analysis of proteins and nuclcic acids transferred to nitrocellulose. Gen. Anal. Tech. 1:3-8.
27. Kaluza, G., R. Rott, and R. Schwarz. 1980. Carbohydrate-induced conformational changes of Semliki forest virus glycoproteins determine antigenicity. Virology 102:286-299.
28. Kang, C.-Y., P. Nara, V. Chamat, V. Caralli, T. Ryskamp, N. Haigwood, R. Newman, and H. Kohler. 1991. Evidence for non-V3 specific neutralizing antibodies in HIV-1 infected humans which interfere with gp120/CD4 binding. Proc. Natl. Acad. Sci. USA 88:6171-6175.
29. Kinoshita, T., A. Tsujimoto, and K. Shimotohno. 1991. Sequence variations in I.TR and env regions of HTLV-I do not discriminate between the virus from patients with HTLV-I associated myelopathy and adult T-cell leukemia, Int. J. Cancer 47:491-495.
30. Kiyokawa, T., H. Yoshikura, S. Hattori, M. Seiki, and M. Yoshida. 1984. Envelope proteins of human T-cell leukemia virus: expression in Escherichia coli and its application to studies of env gene functions. Proc. Natl. Acad. Sci. USA 81:6202-6206.
31. Klenk, H. 1980. Processing of the hemagglutinin: glycosylation and proteolytic cleavage, p. 213-222. In W. Laver and G. Air (ed.). Structure and variation in influenza virus. Elsevier/North Holland, Amsterdam.
32. Komurian, F., F. Pelloquin, and G. De Thé. 1991. In vivo genetic variability of human T-cell leukemia virus type I depends more upon geography than upon pathologies. J. Virol. 65:3770-3778.
33. Kornfeld, R., and S. Kornfeld. 1985. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem. 54:631-664.
34. Kuga, T., S. Hattori, M. Yoshida, and T. Taniguchi. 1986. Expression of human T-cell leukemia virus type I envelope protein in Saccharomyces cer-evisiae. Gene 44:337-340.
35. Lagrenade, L., B. Hanchard, V. Fletcher, B. Cranston, and W. Blattner. 1990. Infective dermatitis of Jamaican children: a murker for HTLV-I infection. Lancet 336:1345-1347.
36. Lee, T., J. Coligan, T. Homma, M. McLane, N. Tachibana, and M. Essex. 1984. Human T-cell leukemia virus-associated membrane antigens: identity of the major antigens recognized after virus infection. Proc. Natl. Acad. Sci. USA 81:3856-3860.
37. Li, Y., L. Luo, N. Rassol, and C. Kang. 1993. Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding. J. Virol. 67:584-588.
38. Lillehoj, E., C. Tal, A. Nguyen, and S. Alexander. 1989. Characterization of env and tax encoded polypeptides of human T-cell leukemia virus type I. Clin. Biotechnol. 1:27-41.
39. Lipka, J., K. Bui, G. Reyes, R. Moeckli, S. Wiktor, W. Blattner, E. Murphy, G. Shaw, C. Hanson, J. Sninsky, and S. Foung. 1990. Determination of a unique and immunodominant epitope of human T cell lymphotropic virus type I. J. Infect. Dis, 162:353-357.
40. Mackett, M., G. Smith, and B. Moss. 1984. General method for the production and selection of infectious vaccinia virus recombilants expressing foreign genes. J. Virol. 49:857-864.
41. Mackett, M., G. Smith, and B. Moss. 1985, The construction and characterization of vaccinia virus recombinants expressing foreign genes, p. 191-211. In D. Rickwood and B. D. Hames (ed.), DNA cloning, vol. 2. IRL Press, Washington, D.C.
42. + T cells can discriminate the molecular and structural context of T epitopes of HIV gp120 and HIV p66. J. Acquired Immune Defic. Syndr. 9:227-237.
43. + T cell lines generated from HTLV-I seronegative individuals. Blood 85:1547-1554.
44. Matsushita, S., M. Robert-Guroff, J. Trepel, J. Cossman, H. Mitsuya, and S. Broder. 1986. Human monoclonal antibody directed against an envelope glycoprotein of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. USA 83:2672-2676.
45. Misumi, Y., Y. Misumi, K. Miki, A. Takatsuki, G. Tamura, and Y. Ikehara. 1986. Novel blockade by Brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J. Biol. Chem. 261:11398-11403.
46. Mochizuki, M., T. Watanabe, K. Yamaguchi, K. Takatsuki, M. Shirao, S. Nakashima, S. Mori, S. Araki, and N. Miyata. 1992. HTLV-I uveitis: a distinct clinical entity caused by HTLV-I. Jpn. J. Cancer Res. 83:236-239.
47. Moore, J., J. McKeating, I. Jones, P. Stephens, G. Clements, S. Thompson, and R. Weiss. 1990. Characterization of recombinant gp120 and gp160 from HIV-1 binding to monoclonal antibodies and soluble CD4. AIDS 4:307-315.
48. Nyunoya, H., T. Ogura, M. Kikuchi, H. Iwamoto, K. Yamashita, M. Maekawa, Y. Takebe, K. Miyamura, S. Yamazaki, and K. Shimotohno. 1990. Expression of HTLV-I envelope protein to hydrophobic amino-terminal peptide of baculovirus polyhedrin in insect cells and its application for scrological assays. AIDS Res. Hum. Retroviruses 6:1311-1321.
49. Osame, M., K. Usuku, S. Izumo, N. Ijichi, H. Amitani, A. ,Igata, M. Matsumoto, and M. Tara. 1986. HTLV-I associated myelopathy, a new clinical entity. Lancet 1:1031-1032.
50. Palker, T., R. Scearce, S. Miller, M. Popovic, D. Bolognesi, R. Gallo, and B. Haynes. 1984. Monoclonal antibodies against human T-cell leukemia-lymphoma virus (HTLV) p24 internal core protein. J. Exp. Med. 159:1117-1125.
51. Palker, T., M. Tanner, R. Scearce, R. Streilein, M. Clark, and B. Haynes. 1989. Mapping of immunogenic regions of human T-cell leukemia type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46. J. Immunol. 142:971-978.
52. Perkins, S., and S. Foung. 1995. Stabilizing antibody secretion of human Epstein-Barr virus activated B lymphocytes with hybridoma formation by electrofusion. Methods Mol. Biol. 48:295-307.
53. Perkins, S., U. Zimmermann, and S. Foung. 1991. Parameters to enhance hybridoma formation with hypo-osmolar electrofusion. Hum. Antibod. Hybridomas 2:155-159.
54. Ix antigen of murine leukemia virus: an analysis with monoclonal antibodies. Virology 112:450-460.
55. Pique, C., D. Pham, T. Tursz, and M.-C. Dokhelar. 1992. Human T-cell leukemia virus type 1 envelope protein maturation process: requirements for syncytium formation. J. Virol. 66:906-913.
56. Pique, C., T. Tursz, and M.-C. Dokhelar. 1990. Mutations introduced along the HTLV-I envelope gene result in a non-functional protein: a basis for envelope conservation? EMBO J. 9:4243-4248.
57. Plummer, T., Jr., J. Elder, S. Alexander, A. Phelan, and A. Tarentino. 1984. Demonstration of peptide:N-glycosidase F activity in endo-beta-N-acetylglucoaminidase F preparations. J. Biol. Chem. 259:10700-10704.
58. Rademacher, T. 1992. Therapeutic challenges: does glycobiology have a role. Trends Biotechnol. 10:227-230.
59. Rademacher, T., R. Parekh, and R. Dwek. 1988. Glycobiology. Annu. Rev. Biochem. 57:785-838.
60. Ratner, L., S. Josephs, B. Starcich, B. Hahn, G. Shaw, R. Gallo, and F. Wong-Staal. 1985. Nucleotide sequence analysis of a variant human T-cell leukemia virus (HTLV-Ib) provirus with a deletion in pX-I. J. Virol. 54:781-790.
61. Robert-Guroff, M., Y. Nakao, K. Notake, Y. Ito, A. Sliski, and R. Gallo. 1982. Natural antibodies to human retrovirus HTLV in a cluster of Japanese patients with adult T cell leukemia. Science 215:975-978.
62. Rowe, J., S. Perkins, P. Bradshaw, G.-Y. Song, and S. Foung. 1994. Neutralizing HTLV-human monoclonal antibodies (HMAbs) to conformational epitopes. AIDS Res. Hum. Retroviruses 10:509.
63. Samuel, K., J. Lautenherger, C. Jorcyk, S. Josephs, F. Wong-Staal, and T. Papas. 1984. Diagnostic potential for human malignancies of bacterially produced HTLV-I envelope glycoprotein. Science 226:1094-1097.
64. Sattentau, Q., and J. Moore. 1995. HIV-1 neutralization is determined by epitope exposure on the gp120 oligomer. J. Exp. Med. 182:185-196.
65. Schwarz, R., and R. Datema. 1982. Inhibition of the dolichol pathway of protein glycosylation. Methods Enzymol. 83:432-143.
66. Seiki, M., S. Hattori, Y. Hirayama, and M. Yoshida. 1983. Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. Proc. Natl. Acad. Sci. USA 80:3618-3622.
67. Sodora, D., G. Cohen, M. Muggeridge, and R. Eisenberg. 1991. Absence of asparagine-linked oligosaccharides from glycoprotein D of herpes simplex virus type 1 results in a structurally altered by biologically active protein. J. Virol. 65:4424-4431.
68. Stamatatos, L., and C. Cheng-Mayer. 1995. Structural modulations of the envelope gp120 glycoprotein of human immunodeficiency virus type 1 upon oligomerization and differential V3 loop epitope exposure of isolates displaying distinct tropism upon virion-soluble receptor binding. J. Virol. 69: 6191-6198.
69. Sugawara, K., F. Kitame, H. Nishimura, and K. Nakamura. 1988. Operational and topological analyses of antigenic sites on influenza virus glycoprotein and their dependence on glycosylation. J. Gen. Virol. 69:537-547.
70. Trimble, R., and G. Maley. 1984. Optimizing hydrolysis of N-linked high-mannose oligosaccharides by endo-beta-N-acetyl-glucosaminidase H. Anal. Biochem. 141:515-522.
71. van Drunen Littel-van den Hurk, S., G. Hughes, and L. Bahiuk. 1990. The role of carbohydrate in the antigenic and immunogenic structure of bovine herpesvirus type 1 glycoproteins gI and gIV. J. Gen. Virol. 71:2053-2063.
72. Varki, A. 1993. Biological roles of oligosaccharides: all of the theories are correct. Glycobiology 3:97-130.
73. Vidal, S., G. Mottet, D. Kolakofsky, and L. Roux. 1989. Addition of high-mannose sugars must precede disulfide bond formation for proper folding of Sendai virus glycoproteins. J. Virol. 63:892-900.
74. Vile, R., T. Schulz, O. Danos, M. Collins, and R. Weiss. 1991. A murine cell line producing HTLV-I pseudotype virions carrying a selectable marker gene. Virology 180:420-424.
75. Yoshida, M., M. Seiki, K. Yamaguchi, and K. Takatsuki. 1984. Monoclonal integration of human T-cell leukemia provirus in all primary tumours of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease. Proc. Natl. Acad. Sci. USA 81:2534-2537.