-
1
-
-
0029115555
-
The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families
-
Alzheimer's disease collaborative group (1995) The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nat Genet 11: 219-222
-
(1995)
Nat Genet
, vol.11
, pp. 219-222
-
-
-
2
-
-
0023192563
-
Localization of amyloid beta-protein messenger RNA in brains from patients with Alzheimer's disease
-
Bahanmanyar S, Higgins GA, Goldgaber D, Lewis DA, Morrison JH, Wilson MC, Shankar SK, Gajdusek DC (1987) Localization of amyloid beta-protein messenger RNA in brains from patients with Alzheimer's disease. Science 237: 77-80
-
(1987)
Science
, vol.237
, pp. 77-80
-
-
Bahanmanyar, S.1
Higgins, G.A.2
Goldgaber, D.3
Lewis, D.A.4
Morrison, J.H.5
Wilson, M.C.6
Shankar, S.K.7
Gajdusek, D.C.8
-
3
-
-
0024587074
-
Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease
-
Bancher C, Brunner C, Lassman H, Budka H, Jellinger K, Wiche G, Seitelberger F, Grundke-Iqbal I, Wisniewski HM (1989) Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res 477: 90-99
-
(1989)
Brain Res
, vol.477
, pp. 90-99
-
-
Bancher, C.1
Brunner, C.2
Lassman, H.3
Budka, H.4
Jellinger, K.5
Wiche, G.6
Seitelberger, F.7
Grundke-Iqbal, I.8
Wisniewski, H.M.9
-
4
-
-
0026551711
-
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
-
Biernat J, Mandelkow E-M, Schröter C, Lichtenberg-Kraag B, Steiner B, Berling B, Meyer H, Mercken M, Vandermeeren A, Goedert M, Mandelkow E (1992) The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. EMBO J 11: 1593-1597
-
(1992)
EMBO J
, vol.11
, pp. 1593-1597
-
-
Biernat, J.1
Mandelkow, E.-M.2
Schröter, C.3
Lichtenberg-Kraag, B.4
Steiner, B.5
Berling, B.6
Meyer, H.7
Mercken, M.8
Vandermeeren, A.9
Goedert, M.10
Mandelkow, E.11
-
5
-
-
0024602479
-
Tau, paired helical filaments and amyloid in the neocortex: A morphometric study of 15 cases with graded intellectual status in aging and senile dementia of Alzheimer's type
-
Delaère P, Duyckaerts C, Brion JP, Poulain V, Hauw J-J (1989) Tau, paired helical filaments and amyloid in the neocortex: a morphometric study of 15 cases with graded intellectual status in aging and senile dementia of Alzheimer's type. Acta Neuropathol 77: 645-653
-
(1989)
Acta Neuropathol
, vol.77
, pp. 645-653
-
-
Delaère, P.1
Duyckaerts, C.2
Brion, J.P.3
Poulain, V.4
Hauw, J.-J.5
-
6
-
-
0023495384
-
Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease
-
Goedert M (1987) Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease. EMBO J 6: 3627-3632
-
(1987)
EMBO J
, vol.6
, pp. 3627-3632
-
-
Goedert, M.1
-
7
-
-
0026454256
-
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases
-
Hof PR, Bouras C, Buée L, Delacourte A, Perl DP, Morrison JH (1992) Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. Acta Neuropathol 85: 23-30
-
(1992)
Acta Neuropathol
, vol.85
, pp. 23-30
-
-
Hof, P.R.1
Bouras, C.2
Buée, L.3
Delacourte, A.4
Perl, D.P.5
Morrison, J.H.6
-
8
-
-
0024580845
-
The immunohistochemical demonstration of subsequences of the precursor of the amyloid A4 protein in senile plaques in Alzheimer's disease
-
Ishii T, Kametani F, Haga S, Sato M (1989) The immunohistochemical demonstration of subsequences of the precursor of the amyloid A4 protein in senile plaques in Alzheimer's disease. Neuropathol Appl Neurobiol 15: 135-147
-
(1989)
Neuropathol Appl Neurobiol
, vol.15
, pp. 135-147
-
-
Ishii, T.1
Kametani, F.2
Haga, S.3
Sato, M.4
-
9
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J, Lemaire H-G, Unterbeck A, Salbaum J, Masters C, Grzeschik K, Multhaup G, Beyreuther K, Müller-Hill B (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.-G.2
Unterbeck, A.3
Salbaum, J.4
Masters, C.5
Grzeschik, K.6
Multhaup, G.7
Beyreuther, K.8
Müller-Hill, B.9
-
10
-
-
0025056563
-
Precursor of amyloid protein in Alzheimer's disease undergoes fast anterograde transport
-
Koo EH, Sisodia SS, Archer DR, Martin LJ, Weidemann A, Beyreuther K, Fischer P, Masters CL, Price DL (1990) Precursor of amyloid protein in Alzheimer's disease undergoes fast anterograde transport. Proc Natl Acad Sci USA 87: 1561-1565
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 1561-1565
-
-
Koo, E.H.1
Sisodia, S.S.2
Archer, D.R.3
Martin, L.J.4
Weidemann, A.5
Beyreuther, K.6
Fischer, P.7
Masters, C.L.8
Price, D.L.9
-
11
-
-
0028833215
-
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
-
Lassmann H, Bancher C, Breitschopf H, Wegiel J, Bobinski M, Jellinger K, Wisniewski HM (1995) Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropathol 89: 35-41
-
(1995)
Acta Neuropathol
, vol.89
, pp. 35-41
-
-
Lassmann, H.1
Bancher, C.2
Breitschopf, H.3
Wegiel, J.4
Bobinski, M.5
Jellinger, K.6
Wisniewski, H.M.7
-
12
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu C, Jondro PD, Schmidt SD, Wang K, Crowley AC, Fu Y-H, Guenette SY, Galas D, Nemens E, Wijsman EM, Bird TD, Schellenberg GD, Tanzi RE (1995) Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269: 973-977
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.-H.12
Guenette, S.Y.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
13
-
-
0026758096
-
Monoclonal antibodies with selective specificity for Alzheimer's Tau are directed against phosphatase-sensitive epitopes
-
Mercken M, Vandermeeren M, Lübke U, Six J, Boons J, Van de Voorde A, Martin J-J, Gheuens J (1992) Monoclonal antibodies with selective specificity for Alzheimer's Tau are directed against phosphatase-sensitive epitopes. Acta Neuropathol 84: 265-272
-
(1992)
Acta Neuropathol
, vol.84
, pp. 265-272
-
-
Mercken, M.1
Vandermeeren, M.2
Lübke, U.3
Six, J.4
Boons, J.5
Van De Voorde, A.6
Martin, J.-J.7
Gheuens, J.8
-
14
-
-
0027985477
-
A study of apoptosis in nomal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks
-
Migheli A, Cavalla P, Marino S, Schiffer D (1994) A study of apoptosis in nomal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks. J Neuropathol Exp Neurol 53: 606-616
-
(1994)
J Neuropathol Exp Neurol
, vol.53
, pp. 606-616
-
-
Migheli, A.1
Cavalla, P.2
Marino, S.3
Schiffer, D.4
-
15
-
-
0027254967
-
Amyloid precursor protein is synthesized by retinal ganglion cells, rapidly transported to the optic nerve plasma membrane and nerve terminals, and metabolized
-
Morin PJ, Abraham CR, Amaratunga A, Johnson RJ, Huber G, Sandell JH, Fine RE (1993) Amyloid precursor protein is synthesized by retinal ganglion cells, rapidly transported to the optic nerve plasma membrane and nerve terminals, and metabolized. J Neurochem 61: 464-473
-
(1993)
J Neurochem
, vol.61
, pp. 464-473
-
-
Morin, P.J.1
Abraham, C.R.2
Amaratunga, A.3
Johnson, R.J.4
Huber, G.5
Sandell, J.H.6
Fine, R.E.7
-
16
-
-
0023729858
-
Antisera to an amino-terminal peptide detect the amyloid precursor of Alzheimer's disease and recognize senile plaques
-
Palmert MR, Podlinsky MB, Witkar DS, Oltersdorf T, Younkin L, Selkoe D, Younkin S (1988) Antisera to an amino-terminal peptide detect the amyloid precursor of Alzheimer's disease and recognize senile plaques. Biochem Biophys Res Commun 156: 432-437
-
(1988)
Biochem Biophys Res Commun
, vol.156
, pp. 432-437
-
-
Palmert, M.R.1
Podlinsky, M.B.2
Witkar, D.S.3
Oltersdorf, T.4
Younkin, L.5
Selkoe, D.6
Younkin, S.7
-
17
-
-
0023706899
-
Amyloid precursor protein is in senile plaques of Alzheimer's disease
-
Perry G, Lipphardt S, Mulvihill P, Kancherla M, Mijares M, Gambetti P, Sharma S, Maggiora L, Cornette J, Lobl T, Greenberg B (1988) Amyloid precursor protein is in senile plaques of Alzheimer's disease. Lancet II: 746
-
(1988)
Lancet
, vol.2
, pp. 746
-
-
Perry, G.1
Lipphardt, S.2
Mulvihill, P.3
Kancherla, M.4
Mijares, M.5
Gambetti, P.6
Sharma, S.7
Maggiora, L.8
Cornette, J.9
Lobl, T.10
Greenberg, B.11
-
18
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev EI, Sherrington R, Rogaeva EA, Levesque G, Ikeda M, Liang Y, Chi H, Lin Cs, Holman K, Tsuda T, Mar L, Sorbi S, Nacmias B, Placentini S, Amaducci L, Chumakov I, Cohen D, Lannfelt L, Fraser PE, Rommens JM, St. George-Hyslop PH (1995) Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376: 775-778
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, Cs.8
Holman, K.9
Tsuda, T.10
Mar, L.11
Sorbi, S.12
Nacmias, B.13
Placentini, S.14
Amaducci, L.15
Chumakov, I.16
Cohen, D.17
Lannfelt, L.18
Fraser, P.E.19
Rommens, J.M.20
St. George-Hyslop, P.H.21
more..
-
19
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin J-F, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Poilen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HAR, Haines JL, Pericak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St. George-Hyslop PH (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375: 754-760
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.-F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Poilen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
Da Silva, H.A.R.26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Rommens, J.M.32
St. George-Hyslop, P.H.33
more..
-
20
-
-
0027212769
-
Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system
-
Sisodia SS, Koo EH, Hoffman PN, Perry G, Price DL (1993) Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system. J Neurosci 13: 3136-3142
-
(1993)
J Neurosci
, vol.13
, pp. 3136-3142
-
-
Sisodia, S.S.1
Koo, E.H.2
Hoffman, P.N.3
Perry, G.4
Price, D.L.5
-
21
-
-
0029671219
-
2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3
-
2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science 271: 521-524
-
(1996)
Science
, vol.271
, pp. 521-524
-
-
Vito, P.1
Lacaná, E.2
D'Adamio, L.3
-
22
-
-
0028822488
-
S182 protein in Alzheimer's disease neuritic plaques
-
Wisniewski T, Palha JA, Ghiso J (1995) S182 protein in Alzheimer's disease neuritic plaques. Lancet 346: 1366
-
(1995)
Lancet
, vol.346
, pp. 1366
-
-
Wisniewski, T.1
Palha, J.A.2
Ghiso, J.3
|