메뉴 건너뛰기




Volumn 48, Issue 5, 1996, Pages 501-502

Pulmonary microsomal metabolism of benzo[a]pyrene following exposure of rats to silica

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE; BENZO[A]PYRENE DERIVATIVE; CYTOCHROME P450; OXYGENASE; SILICON DIOXIDE; TOXIN; UNSPECIFIC MONOOXYGENASE;

EID: 0029843136     PISSN: 00984108     EISSN: None     Source Type: Journal    
DOI: 10.1080/009841096161203     Document Type: Article
Times cited : (7)

References (29)
  • 1
    • 0015624014 scopus 로고
    • Metabolic conversion of benzo(A)pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid
    • Borgen, A., Darvey, H., Castagnoli, N., Crocker, T. T., Rasmussen, R. E., and Wang, I. Y. 1973. Metabolic conversion of benzo(a)pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid. J. Med. Chem. 16:502-506.
    • (1973) J. Med. Chem. , vol.16 , pp. 502-506
    • Borgen, A.1    Darvey, H.2    Castagnoli, N.3    Crocker, T.T.4    Rasmussen, R.E.5    Wang, I.Y.6
  • 2
    • 21544464160 scopus 로고
    • Metabolism of benzo(A)-pyrene in reconstituted monooxygenase systems containing rabbit cytochrome P-450 forms 2 and 6
    • Cheung, E. N., Domin, B. A., Philpot, R. M., and Bend, J. R. 1984. Metabolism of benzo(a)-pyrene in reconstituted monooxygenase systems containing rabbit cytochrome P-450 forms 2 and 6. Pharmacologist 26:169.
    • (1984) Pharmacologist , vol.26 , pp. 169
    • Cheung, E.N.1    Domin, B.A.2    Philpot, R.M.3    Bend, J.R.4
  • 3
    • 0025072154 scopus 로고
    • Pulmonary metabolism of foreign compounds: Its role in metabolic activation
    • Cohen, G. M. 1990. Pulmonary metabolism of foreign compounds: Its role in metabolic activation. Environ. Health Perspect. 85:31-41.
    • (1990) Environ. Health Perspect. , vol.85 , pp. 31-41
    • Cohen, G.M.1
  • 4
    • 0018090784 scopus 로고
    • The metabolism of polycyclic hydrocarbons and its relationship to cancer
    • Depierre, J. W., and Ernster, L. 1978. The metabolism of polycyclic hydrocarbons and its relationship to cancer. Biochim. Biophys. Acta 473:149-186.
    • (1978) Biochim. Biophys. Acta , vol.473 , pp. 149-186
    • Depierre, J.W.1    Ernster, L.2
  • 6
    • 0024535776 scopus 로고
    • Xenobiotic metabolism by isolated pu l-monary cells
    • Devereux, T. R., Domin, B. A., and Philpot, R. M. 1989. Xenobiotic metabolism by isolated pu l-monary cells. Pharmacol. Ther. 41:243-256.
    • (1989) Pharmacol. Ther. , vol.41 , pp. 243-256
    • Devereux, T.R.1    Domin, B.A.2    Philpot, R.M.3
  • 7
    • 0022523266 scopus 로고
    • The effect of substrate on the expression of activity catalyzed by cytochrome P-450: Metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems
    • Domin, B. A., and Philpot, R. M. 1986. The effect of substrate on the expression of activity catalyzed by cytochrome P-450: Metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems. Arch. Biochem. Biophys. 246:128-142.
    • (1986) Arch. Biochem. Biophys. , vol.246 , pp. 128-142
    • Domin, B.A.1    Philpot, R.M.2
  • 8
    • 0025408909 scopus 로고
    • Pulmonary response to silica or titanium dioxide: Inflammatory cells, alveolar macrophage-derived cytokines, and histopathology
    • Driscoll, K. E., Lindenschmidt, R. C., Maurer, J. K., Higgins, J. M., and Ridder, G. 1990. Pulmonary response to silica or titanium dioxide: inflammatory cells, alveolar macrophage-derived cytokines, and histopathology. Am. J. Respir. Cell Mol. Biol. 2:381-390.
    • (1990) Am. J. Respir. Cell Mol. Biol. , vol.2 , pp. 381-390
    • Driscoll, K.E.1    Lindenschmidt, R.C.2    Maurer, J.K.3    Higgins, J.M.4    Ridder, G.5
  • 9
    • 0019074870 scopus 로고
    • Benzo(A)pyrene metabolism, activation, and carcinogenesis: Role and regulation of mixed-function oxidases and related enzymes
    • Gelboin, H. V. 1980. Benzo(a)pyrene metabolism, activation, and carcinogenesis: Role and regulation of mixed-function oxidases and related enzymes. Physiol. Rev. 60:1107-1166.
    • (1980) Physiol. Rev. , vol.60 , pp. 1107-1166
    • Gelboin, H.V.1
  • 10
    • 6844263308 scopus 로고
    • Combined silica exposure and cigarette smoking: A likely synergistic effect
    • D. F. Goldsmith, D. M. Winn, and C. M. Shy, New York: Praeger
    • Goldsmith, D. F., and Guidotti, T. L. 1986. Combined silica exposure and cigarette smoking: a likely synergistic effect. In Silica, silicosis, and cancer: Controversy in occupational medicine, eds. D. F. Goldsmith, D. M. Winn, and C. M. Shy, pp. 451-459. New York: Praeger.
    • (1986) Silica, Silicosis, and Cancer: Controversy in Occupational Medicine , pp. 451-459
    • Goldsmith, D.F.1    Guidotti, T.L.2
  • 11
    • 0020359044 scopus 로고
    • Does occupational exposure to silica cause lung cancer?
    • Goldsmith, D. F., Guidotti, T. L., and Johnston, D. R. 1982. Does occupational exposure to silica cause lung cancer? Am. J. Ind. Med. 3:423-440.
    • (1982) Am. J. Ind. Med. , vol.3 , pp. 423-440
    • Goldsmith, D.F.1    Guidotti, T.L.2    Johnston, D.R.3
  • 12
    • 0023951396 scopus 로고
    • Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy
    • Guengerich, F. P. 1988. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res. 48:2946-2954.
    • (1988) Cancer Res , vol.48 , pp. 2946-2954
    • Guengerich, F.P.1
  • 13
    • 0025895757 scopus 로고
    • Reactions and significance of cytochrome P-450 enzymes
    • Guengerich, F. P. 1991. Reactions and significance of cytochrome P-450 enzymes. J. Biol. Chem. 266:10019-10022.
    • (1991) J. Biol. Chem. , vol.266 , pp. 10019-10022
    • Guengerich, F.P.1
  • 14
    • 0021867158 scopus 로고
    • Silica, pneumoconiosis, and carcinoma of the lung
    • Heppleston, A. G. 1985. Silica, pneumoconiosis, and carcinoma of the lung. Am. J. Ind. Med. 7:285-294.
    • (1985) Am. J. Ind. Med. , vol.7 , pp. 285-294
    • Heppleston, A.G.1
  • 15
    • 0015396622 scopus 로고
    • Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver
    • Hook, G. E. R., Bend, J. R., Hoel, D., Fouts, J. R., and Gram, T. E. 1972. Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver. J. Pharmacol. Exp. Ther. 182:474-480.
    • (1972) J. Pharmacol. Exp. Ther. , vol.182 , pp. 474-480
    • Hook, G.E.R.1    Bend, J.R.2    Hoel, D.3    Fouts, J.R.4    Gram, T.E.5
  • 16
    • 21544440782 scopus 로고
    • Silica and some silicates
    • Lyon: IARC
    • International Agency for Research on Cancer. 1987. Silica and some silicates. Monogr. Evalu. Carcinogen. Risk Chem. Hum. 42:39-143. Lyon: IARC.
    • (1987) Monogr. Evalu. Carcinogen. Risk Chem. Hum , vol.42 , pp. 39-143
  • 17
    • 0022480831 scopus 로고
    • Effects of organic solvent vehicles on benzo(A)pyrene metabolism in rabbit lung microsomes
    • Kontir, D. M., Glance, C. A., Colby, H. D., and Miles, P. R. 1986. Effects of organic solvent vehicles on benzo(a)pyrene metabolism in rabbit lung microsomes. Biochem. Pharmacol. 35:2569-2575.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 2569-2575
    • Kontir, D.M.1    Glance, C.A.2    Colby, H.D.3    Miles, P.R.4
  • 19
    • 0024358520 scopus 로고
    • Silica, silicosis, and lung cancer
    • McDonald, J. C. 1989. Silica, silicosis, and lung cancer. Br. J. Ind. Med. 46:289-291.
    • (1989) Br. J. Ind. Med. , vol.46 , pp. 289-291
    • McDonald, J.C.1
  • 20
    • 0027613986 scopus 로고
    • Alterations in the pulmonary microsomal P-450 system following exposure of rats to silica
    • Miles, P. R., Bowman, L., and Miller, M. R. 1993. Alterations in the pulmonary microsomal P-450 system following exposure of rats to silica. Am. J. Respir. Cell Mol. Biol. 8:597-604.
    • (1993) Am. J. Respir. Cell Mol. Biol. , vol.8 , pp. 597-604
    • Miles, P.R.1    Bowman, L.2    Miller, M.R.3
  • 21
    • 0023567442 scopus 로고
    • Progression of type II cell hypertrophy and hyperplasia during silica-induced pulmonary inflammation
    • Miller, B. E., Dethloff, L. A., and Hook, G. E. R. 1987. Progression of type II cell hypertrophy and hyperplasia during silica-induced pulmonary inflammation. Lab. Invest. 57:546-554.
    • (1987) Lab. Invest. , vol.57 , pp. 546-554
    • Miller, B.E.1    Dethloff, L.A.2    Hook, G.E.R.3
  • 22
    • 0014410265 scopus 로고
    • Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assays and properties of induced enzyme
    • Nebert, D. W., and Gelboin, H. V. 1968. Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assays and properties of induced enzyme. J. Biol. Chem. 243:6242-6249.
    • (1968) J. Biol. Chem. , vol.243 , pp. 6242-6249
    • Nebert, D.W.1    Gelboin, H.V.2
  • 23
    • 0020523616 scopus 로고
    • Fifty years of benzo(A)pyrene
    • Phillips, D. H. 1983. Fifty years of benzo(a)pyrene. Nature 303:468-472.
    • (1983) Nature , vol.303 , pp. 468-472
    • Phillips, D.H.1
  • 24
    • 0021288082 scopus 로고
    • Role of cytochrome P-450 and related enzymes in the pulmonary metabolism of xenobiotics
    • Philpot, R. M., and Smith, B. R. 1984. Role of cytochrome P-450 and related enzymes in the pulmonary metabolism of xenobiotics. Environ. Health Perspect. 55:359-367.
    • (1984) Environ. Health Perspect. , vol.55 , pp. 359-367
    • Philpot, R.M.1    Smith, B.R.2
  • 25
    • 0018456940 scopus 로고
    • Characteristics of benzo(A)pyrene metabolism by kidney, liver, and lung microsomal fractions from rodents and humans
    • Prough, R. A., Patrizi, V. W., Okita, R. T., Masters, S. S., and Jakobsson, S. W. 1979. Characteristics of benzo(a)pyrene metabolism by kidney, liver, and lung microsomal fractions from rodents and humans. Cancer Res. 39:1199-1206.
    • (1979) Cancer Res , vol.39 , pp. 1199-1206
    • Prough, R.A.1    Patrizi, V.W.2    Okita, R.T.3    Masters, S.S.4    Jakobsson, S.W.5
  • 26
    • 0016328890 scopus 로고
    • Metabolic activation of benzo(A)pyrene proceeds by a diol-epoxide
    • Sims, P., Grover, P. L., Swaisland, A., Pal, K., and Hewer, A. 1974. Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide. Nature 252:326-328.
    • (1974) Nature , vol.252 , pp. 326-328
    • Sims, P.1    Grover, P.L.2    Swaisland, A.3    Pal, K.4    Hewer, A.5
  • 27
    • 0006447324 scopus 로고
    • Determination of succinate dehydrogenase activity
    • Singer, T. P., and Kearney, E. B. 1957. Determination of succinate dehydrogenase activity. Methods Biochem. Anal. 4:307-310.
    • (1957) Methods Biochem. Anal. , vol.4 , pp. 307-310
    • Singer, T.P.1    Kearney, E.B.2
  • 28
    • 0018769955 scopus 로고
    • Experimental respiratory carcinogenesis in hamsters: Environmental, physiochemical, and biological aspects
    • Stenback, F., and Rowland, J. 1979. Experimental respiratory carcinogenesis in hamsters: environmental, physiochemical, and biological aspects. Oncology 36:63-71.
    • (1979) Oncology , vol.36 , pp. 63-71
    • Stenback, F.1    Rowland, J.2
  • 29
    • 0018949498 scopus 로고
    • Silica-induced malignant histiocytic lymphoma: Incidence linked with strain of rat and type of silica
    • Wagner, M. M. F., Wagner, J. C., Davis, R., and Griffiths, D. M. 1980. Silica-induced malignant histiocytic lymphoma: incidence linked with strain of rat and type of silica. Br. J. Cancer 41:908-917.
    • (1980) Br. J. Cancer , vol.41 , pp. 908-917
    • Wagner, M.M.F.1    Wagner, J.C.2    Davis, R.3    Griffiths, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.