Enhanced biosynthesis of extracellular matrix proteins and TGF-β1 by polyinosinic-polycytidylic acid during cutaneous wound healing in vivo

Journal of Cellular Physiology

Volumn 169, Issue 1, 1996, Pages 108-114

  Sidhu, Gurmel S ^a   Thaloor, Deepa ^a   Singh, Anoop K ^a   Raghunath, Puthiyaveettil N ^a   Maheshwari, Radha K ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; INTERCELLULAR ADHESION MOLECULE 1; LAMININ; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; WOUND HEALING;

ANIMALS; COLLAGEN; EXTRACELLULAR MATRIX PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; IN SITU HYBRIDIZATION; INTERCELLULAR ADHESION MOLECULE-1; LAMININ; MALE; MICE; MICE, INBRED STRAINS; POLY I-C; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; TRANSFORMING GROWTH FACTOR BETA; VASCULAR CELL ADHESION MOLECULE-1; WOUND HEALING;

ANIMALIA;

EID: 0029842616     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199610)169:1<108::AID-JCP11>3.0.CO;2-9     Document Type: Article

References (20)

1. Bhartiya, D., Sklarsh, J.W., and Maheshwari, R.K. (1992) Enhanced wound healing in animal models by interferon and interferon inducer. J. Cell. Physiol., 150:312-319.
2. Brown, R.L., Breeden, M.P., and Greenhalgh, D.G. (1994) PDGF and TGF-α act synergistically to improve wound healing in genetically diabetic mouse. J. Surg. Res., 56:562-567.
3. Clark, R.A.F. (1989) Wound repair. Curr. Opin. Cell Biol., 1:1000-1008.
4. Clark, R.A.F. (1990) Fibronectin matrix deposition and fibronectin receptor expression in healing and normal skin. J. Invest. Dermatol., 94:128S-134S.
5. Diamond, S.L., Sharefkin, J.B., Dieffenbach, C., Frasier-Scott, K., McIntire, L.V., and Eskin, S.G. (1990) Tissue plasminogen activator messenger RNA levels increase in cultured human endothelial cells exposed to laminar shear stress. J. Cell. Physiol., 143:364-371.
6. Doukas, J., Cutler, A.H., and Mordes, J.P. (1994) Polyinosinic-polycytidylic acid is a potent activator of endothelial cells. Am. J. Pathol., 145:137-147.
7. Fujikawa, L.S., Foster, C.S., Havrist, T.J., Lanigan, J.M., and Cavin, R.B. (1981) Fibronectin in healing rabbit corneal wounds. Lab. Invest., 45:120-126.
8. Grinnel, F. (1992) Wound repair, keratinocyte activation and integrin modulation. J. Cell. Sci., 101:1-5.
9. Hunt, T.K. (1988) A retrospective perspective on the nature of wound in growth factors and other aspects of wound healing In: Biological and Clinical Implications. A. Barbul, E. Pines, M. Caldwell, and T.K. Hunt, eds. Alan R Liss, Inc., Philadelphia, pp. XIII-XX.
10. Kirsner, R.S., and Eaglestein, W.H. (1993) The wound healing process. Dermatol. Clin., 11:629-640.
11. Martin, P., Hopkinson-Wooley, J., and McClusky, J. (1992) Growth factors and cutaneous wound repair. Prog. Growth Factor Res., 4:24-44.
12. McDonald, J.A. (1989) Receptors for extracellular matrix components. Am. J. Physiol., 257:L331-L337.
13. Mustoe, T.A., Pierce, G.F., Thomason, A., Gramates, P., Sporn, M.B., and Deuel, T.F. (1987) Accelerated healing of incisional wounds in rats induced by transforming growth factor-β. Science, 237:1333-1335.
14. Mustoe, T.A., Pierce, G.F., Morishima, C., and Deuel, T.F. (1991) Growth factor induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model. J. Clin. Invest., 87:694-703.
15. Peltonen, J., Jaakkola, S., Gay, K., Olsen, D.R., Chu, M.L., and Uitto, J. (1989) Expression of extracellular matrix gene by cultured human cells: Localization of messenger RNAs and antigenic epitopes. Anal. Biochem., 178:184-193.
16. Raghow, R. (1994) The role of extracellular matrix in post inflammatory wound healing and fibrosis. FASEB J., 8:823-831.
17. Rothe, M., and Flanga, V. (1989) Growth factors: Their biology and promise in dermatologic diseases and tissue repair. Arch. Dermatol., 125:1390-1398.
18. Snapper, C.M., Yamaguchi, H., Urban, J.F. Jr., and Finkelman, F.D. (1991) Induction of Ly-6A/E expression by murine lymphocytes after in vivo immunization is strictly dependent upon the activation of IFN-α/β and/or IFN-γ. Int. Immunol., 9:845-852.
19. Varga, J., Rosenbloom, J., and Jimenez, S.A. (1987) Transforming growth factor β causes a persistant increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal dermal fibroblasts. Biochem. J., 247:597-604.
20. Yang, J., Xu, Y., Zhu, X., Hagan, M.K., Lawley, T., and Offermann, M.K. (1994) Regulation of adhesion molecule expression in Kaposi's sarcoma cells. J. Immunol., 152:361-373.