Synthesis and conformational analysis of a series of 1-benzopyrano[3,4-b][1,4]oxazines structurally related to cromakalim

Pharmazie

Volumn 51, Issue 11, 1996, Pages 836-839

  Wolf, C ^a   Weiss Greiler, P ^a   Wolschann, P ^a   Ecker, G ^a   Fleischhacker, W ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZOPYRANO[3,4 B][1,4]OXAZINE DERIVATIVE; 1,4 OXAZINE DERIVATIVE; CROMAKALIM; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; THEORY;

EID: 0029842144     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Palmer, W. J. (ed.): ID research alerts Potassium Channel Modulators, Current Drugs, London 1996.
2. Robertson, D. W.; Steinberg, M. I.: J. Med. Chem. 33, 1529 (1990)
3. Evans, J. M.; Hadley, M. S.; Stemp, G.; in: Weston, A. H.; Hamilton, T. C.: Potassium Channel Modulators, p. 341 Blackwell Scientific Publications, London-Edinburgh-Boston-Melbourne-Paris-Berlin-Vienna 1992
4. Gericke, R.; Harting, J.; Lues, I.; Schittenhelm, C.: J. Med. Chem. 34, 3074 (1991)
5. Julian, D. R.; Matusiak, Z. S.: J. Heterocycl. Chem. 1179 (1975)
6. Ashwood, V. A.; Cassidy, F.; Coldwell, M. C; Evans, J. M.; Hamilton, T. C.; Howlett, D. R.; Smith, D. M.; Stemp, G.: J. Med. Chem. 33, 2667 (1990)
7. Atwal, K. S., Grover, G. J.; Ferrara, F. N.; Ahmed, S. Z.; Sleph, P. G.; Dzwonczyk, S.; Normandin, D. E.: J. Med. Chem. 38, 1966 (1995)
8. Frisch, M. J.; Trucks, G. W.; Schlegel, H. B.; Gill, P. M. W.; Johnson, B. G.; Robb, M. A.; Cheeseman, J. R.; Keith, T. A.; Petersson, G. A.; Montgomery, J. A.; Raghavachari, K.; Al-Laham, M. A.; Zakrzewski, V. G.; Ortiz, J. V.; Foresman, J. B.; Cioslowski, J.; Stefanov, B. B.; Nanayakkara, A.; Challacombe, M.; Peng, C. Y.; Ayala, P. Y.; Chen, W.; Wong, M. W.; Andres, J. L.; Replogle, E. S.; Gomberts, R.; Martin, R. L.; Fox, D. J.; Binkley, J. S.; Defrees, D. J.; Baker, J.; Stewart, J. J. P.; Head-Gordon, M.; Gonzalez, C.; Pople, J. A.: Gaussian 94, Revision A.1, Gaussian Inc., Pittsburgh, PA, 1995
9. Brinkley, J. S.; Pople, J. A.; Hehre, W. J.: J. Amer. Chem. Soc. 102, 939 (1980)
10. Lampert, H.; Mikenda, W.; Karpfen, A.: J. Phys. Chem. 100, 7418 (1996)
11. Cassidy, F.; Evans, J. M.; Smith, D. M.; Stemp, G.; Edge, C.; Williams, D. J.: J. Chem. Soc., Chem. Comm. 377 (1989)
12. Lemmens-Gruber, R.; Heistracher, P.: unpublished results
13. Tripos Ass. Inc., München, Germany