Distribution control of metabolic flux

Cell Biochemistry and Function

Volumn 14, Issue 4, 1996, Pages 229-236

  Veech, Richard L ^a   Fell, David A ^b  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b OXFORD BROOKES UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME;

CONCENTRATION RESPONSE; ENZYME REGULATION; METABOLIC REGULATION; PRIORITY JOURNAL; REVIEW;

EID: 0029841696     PISSN: 02636484     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbf.697     Document Type: Review

References (28)

1. Blackman, F. F. (1905) Optima and limiting factors Ann. Bot., 19, 281.
2. Krebs, H. A. (1957) Control of metabolic processes. Endeavour, 16, 125-132
3. Kacser, H. and Burns, J. A. (1973). The control of flux. Symp. Soc. Exp. Biol., 27, 65-104. (Reprinted in Biochem. Soc. Trans., 23, 341-366, 1995).
4. Kacser, H. and Burns, J. A. (1973). The control of flux. Symp. Soc. Exp. Biol., 27, 65-104. (Reprinted in Biochem. Soc. Trans., 23, 341-366, 1995).
5. Heinrich, R. and Rapoport, T A (1974). A linear steady-state treatment of enzymatic chains; general properties, control and effector strength. Eur J. Biochem , 42, 89-95.
6. Heinrich, R. and Rapoport, T A. (1974). A linear steady state treatment of enzymatic chains. Eur J Biochem , 42, 97-105.
7. Fell, D. A. (1992). Metabolic Control Analysis: a survey of theoretical and experimental developments Biochem. J., 286, 313-330
8. Groen, A. K., Wanders, R. J. A., Westerhoff, H. V., van der Meer, R. and Tager, J. M (1982). Quantification of the contribution of various steps to the control of mitochondrial respiration. J. Biol Chem., 257, 2754-2757
9. 2 and air humidity. Planta, 183, 555-566
10. Schaaff, I., Heinisch, J. and Zimmerman, F. K. (1989) Overproduction of glycolytic enzymes in yeast. Yeast, 5, 285-290
11. Davies, S. E. C. and Brindle, K. M (1992). Effects of over-expression of phosphofructokinase on glycolysis in the yeast Saccharomyces cerevisiae. Biochemistry, 31, 4729-4735.
12. Burrell, M. M., Mooney, P. J., Blundy, M., Carter, D., Wilson, F., Green, J., Blundy, K. S. and Rees, T. (1994). Genetic manipulation of 6-phosphofructokinas in potato tubers. Planta, 194, 95-101.
13. Brindle, K. M. (1996). Analysis of metabolic control in vivo using molecular genetics. Cell Biochem. Funct., 14, 000-000.
14. Groen, A. K., van Roermund, R. C., Vervoorn, C. W. T. and Tager, J. M. (1986). Control of gluconeogenesis in rat liver cells, Biochem J. 237, 379-389.
15. Kashiwaya, Y., Sato, K., Tsuchiya, N , Thomas, S., Fell, D. A., Veech, R. L. and Passonneau, J. V. (1994). Control of glucose utilization in working perfused rat heart. J. Biol. Chem., 269, 25502-25514.
16. Morgan, H. E., Randle, P. J. and Regen, D. M. (1959). Biochem. J., 73, 573-579.
17. Brown, G. C., Hafner, R. P. and Brand, M. D. (1990). A 'top-down' approach to the determination of control coefficients in metabolic control theory. Eur. J. Biochem., 188, 321-325.
18. Hafner, R. P., Brown, G. C. and Brand, M. D. (1990). Analysis of the respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory. Eur. J Biochem., 188, 313-319.
19. Quant, P. A. (1993). Experimental application of top-down Control Analysis to metabolic systems. Trends Biochem. Sci., 18, 26-30
20. Buttgereit, F. and Brand, M. D (1995). A hierarchy of ATP-consuming processes in mammalian cells. Biochem. J., 312, 163-167.
21. Small, J. R and Kacser, H. (1993). Responses of metabolic systems to large changes in enzyme activities and effectors. 1. The linear treatment of unbranched chains. Eur. J. Biochem., 213, 613-624.
22. Niederberger, P., Prasad, R., Miozzari, G. and Kacser, H. (1992). A strategy for increasing an in vivo flux by genetic manipulation: the tryptophan system of yeast. Biochem. J., 287, 473-479.
23. Hofmeyr, J.-H. S. and Cornish-Bowden, A. (1991). Quantitative assessment of regulation in metabolic systems. Eur. J. Biochem., 200, 223-236.
24. Nishimura, M., Fedorov, S. and Uyeda, K. (1994). Glucose stimulated synthesis of fructose 2,6 bisphosphate in rat liver. J. Biol. Chem., 269, 26100-26106.
25. Sakurai, T., Johnson, J. H. and Uyeda, K. (1996). Islet fructose 6-phosphate 2-kinase: fructose 2,6-bisphosphatase - isozymic form, expression and characterization. Biochem. Biophys. Res. Commun., 218, 159-163
26. Cassaza, J. P. and Veech, R. L. (1986). The content of pentose-cycle intermediates in liver in starved, fed ad libitum and meal-fed rats. Biochem. J., 236, 635-641.
27. Kacser, H. and Acerenza, L. (1993). A universal method for achieving increases in metabolite production. Eur. J. Biochem., 216, 361-367.
28. Fell, D. A. and Thomas, S. (1995). Physiological control of flux: the requirement for multisite modulation. Biochem. J., 311, 35-39.