Value of technetium-99m HMPAO-labelled leucocyte scintigraphy as an initial screening test in patients suspected of having inflammatory bowel disease

European Journal of Gastroenterology and Hepatology

Volumn 8, Issue 12, 1996, Pages 1195-1200

  Giaffer, Mustafa H ^a,b   Tindale, Wendy B ^a   Holdsworth, Derek ^a  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^b HULL ROYAL INFIRMARY   (United Kingdom)

Author keywords

Indium 111; Inflammatory bowel disease; Irritable bowel syndrome; Technetium 99m HMPAO

Indexed keywords

HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; TROPOLONE IN 111;

ADULT; AGED; ARTICLE; BARIUM ENEMA; CLINICAL TRIAL; CROHN DISEASE; DIAGNOSTIC VALUE; DRUG UPTAKE; ENDOSCOPY; FEMALE; HUMAN; IRRITABLE COLON; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIODIAGNOSIS; SCINTIGRAPHY; SCREENING TEST;

EID: 0029841695     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199612000-00012     Document Type: Article

References (19)

1. Stein DT, Gray GM, Gregory PB, Anderson M, Goodwin DA, McDougall IR: Location and activity of ulcerative and Crohn's colitis by indium-111 leukocyte scan. Gastmenterology 1983, 84:388-393.
2. Saverymuttu SH, Peters AM, Hodgson HJ, Chadwick VS, Lavender JP: Indium-111 autologous leucocyte scanning: comparison with radiology for imaging the colon in inflammatory bowel disease. BMJ 1982, 285:255-257.
3. Saverymuttu SH, Camilleri M, Rees H, Lavender JP, Hodgson HJF, Chadwick VS: Indium-111 granulocyte scanning in the assessment of disease extent and disease activity in inflammatory bowel disease. A comparison with colonoscopy, histology and faecal indium-111 granulocyte excretion. Gastroenterology 1986, 90:1121-1128.
4. Fotherby KJ, Wraight EP, Garforth H, Hunter JO: Indium-111 leucocyte scintigraphy in the investigation and management of inflammatory bowel disease. Postgrad Med J 1986, 62:457-462.
5. Segal AW, Ensell J, Munro JA, Sarner M: Indium-111 tagged leucocytes in diagnosis of inflammatory bowel disease. Lancet 1981, ii:230-232.
6. Saveymuttu SH, Peters AM, Crofton ME, Rees H, Lavender JP, Hodgson HJF, et al.: 111-Indium granulocytes in the detection of inflammatory bowel disease. Gut 1985, 26:955-960.
7. Coleman RE, Black RE, Welch DM, Maxwell JG: Indium-111 labelled leucocytes in the evaluation of suspected abdominal abscesses. Am J Surg 1980, 139:99-104
8. Saverymuttu SH, Peters AM, Lavender JP, Pepys MB, Hodgson HJF, Chadwick VS: Quantitative faecal Indium-111 labelled leukocyte exertion in the assessment of disease in Crohn's disease. Gastroenterology 1983b, 85:1333-1339.
9. m hexamethyl propylene amine oxime for labelling leucocytes and imaging inflammation. Lancet 1986, ii:946-949.
10. Scholmerich J, Schmidt E, Schumichen C, Billman P, Schmidt H, Gerok W: Scintigraphic assessment of bowel involvement and disease activity in Crohn's disease using technetium-99m hexamethyl propylene amine oxime as leukocyte label. Gastroenterology 1988, 95:1287-1293.
11. Giaffer MH, Tindale WB, Barker D, Senior S, Holdsworth CD: Quantification of disease activity in Crohn's disease by computer analysis of Tc-99m hexamethyl propylene amine oxime (HMPAO) labelled leucocyte images. Gut 1993, 34:68-74.
12. Tindale WB, Barber DC, Giaffer MH, Senior S, Holdsworth CD: 99m-Tc HMPAO labelled leucocyte imaging in Crohn's disease: a subtraction technique for the quantitation of disease activity. Clin Phys Physiol Meas 1992, 13:679-683.
13. Lantto E, Jarvi K, Krekela I, Lantto T, Taavitsainen M, Vendenkangas H, et al.: Technetium-99m hexamethyl propylene amine oxime leucocytes in the assessment of disease activity in inflammatory bowel disease. Eur J Nucl Med 1992, 19:14-18.
14. Roddie ME, Peters AM, Danpure HJ, Osman S, Henderson BL, Lavender JP, et al.: Inflammation: imaging with Tc-99m HMPAO labelled leucocytes. Radiology 1988, 166:767-772.
15. Gibson P, Lichtenstein M, Salehi N, Hebbard G, Andrews J: Values of positive technetium-99m leucocyte scans in predicting intestinal inflammation. Gut 1991, 32:1502-1507.
16. Manning AP, Thompson WG, Heaton KW, Morris AF: Towards a positive diagnosis of the irritable bowel. BMJ 1978, 2:653-654.
17. Best WR, Becktel JM, Singleton JW, Kern F: Development of a Crohn's disease activity index. National Co-operative Crohn's disease study, Gastroenterology 1976, 70:439-444.
18. 99mTc hexamethyl propylene amine oxime. Nucl Med Commun 1988, 9:467-475.
19. 111In leucocyte scintigraphy in inflammatory bowel disease. Nucl Med Commun 1992, 13:867-870.