Comparison of in vitro release rates of nitroglycerin by diffusion through a teflon membrane to the USP method

Drug Development and Industrial Pharmacy

Volumn 22, Issue 11, 1996, Pages 1139-1144

  Juhász, Julianna ^a   Mahashabde, Shashank ^b   Sequeira, Joel ^b  

^a UNIVERSITÉ LAVAL   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERYL TRINITRATE; POLITEF; UNCLASSIFIED DRUG; ZYLON;

ARTICLE; CADAVER; CONTROLLED STUDY; DIFFUSION; DISSOLUTION; DRUG FORMULATION; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; MEMBRANE TRANSPORT; REPRODUCIBILITY; SKIN; TECHNIQUE; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0029840839     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.3109/03639049609065950     Document Type: Article

References (7)

1. 14C cortisol in man, J. Invest. Dermatol., 48, 181 (1967).
2. H. I. Maibach, R. J. Feldmann, T. H. Milby, and W. F. Serat, Regional variations in percutaneous penetration in man, Arch. Environ. Health., 23, 208 (1971).
3. A. Rougier, D. Dupuis, C. Lotte, R. Roguet, R. C. Wester, and H. I. Maibrach, Regional variation in man: Measurement by the stripping method, Arch. Dermatol. Res., 278, 465 (1986).
4. A. Orbe and L. O. Sundelölf, A new in vitro model for quantitative study of cream permeability, Int. J. Pharm., 41, 49 (1988).
5. W. J. Addicks, G. L. Flynn, and N. Weiner, Drug transport from thin applications of topical dosage forms: Development of methodology, Pharm. Res., 5, 377 (1988).
6. V. P. Shah, J. Elkins, S. Y. Lam, and J. P. Skelly, Determination of in vitro drug release from hydrocortisone creams, Int. J. Pharm., 53, 53 (1989).
7. S. T. Wu, G. K. Shiu, J. E. Simmons, R. L. Bronaugh, and J. P. Skelly. In vitro release of nitroglycerin from topical products by use of artificial membranes, J. Pharm. Sci., 81, 1153 (1992).