ICAM-1 as a potential target for treatments blocking the host response in stroke

Keio Journal of Medicine

Volumn 45, Issue 3, 1996, Pages 254-262

  Lindsberg, Perttu J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

adhesion molecules; ICAM 1; leukocytes; stroke

Indexed keywords

ALTEPLASE; FIBRINOLYTIC AGENT; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY;

BRAIN ISCHEMIA; CELL MIGRATION; CONFERENCE PAPER; DRUG ACTIVITY; HUMAN; LEUKOCYTE; NONHUMAN; PATHOGENESIS; STROKE;

EID: 0029840694     PISSN: 00229717     EISSN: None     Source Type: Journal    
DOI: 10.2302/kjm.45.254     Document Type: Conference Paper

References (39)

1. Pozzilli C, Lenzi GL, Argentino C, Carolei A, Rasura M, Signore A, Bozzao L, Pozzilli P: Imaging of leukocytic infiltration in human cerebral infarcts. Stroke 1985; 16: 251-255
2. Hallenbeck JM, Dutka AJ, Tanistnma T, Kochanek PM, Kumaroo KK, Thompson CB, Obrenovitch TP, Contreras TJ: Polymorphonuclear leukocyte accumulation in brain regions with low blood flow during the early postischemic period. Stroke 1986; 17: 246-253
3. Wang PY, Kao CH, Mui MY, Wang SJ: Leukocyte infiltration in acute hemispheric ischemic stroke. Stroke 1993; 24: 236-240
4. Garcia JH, Liu KF, Yoshida Y, Lian J. Chen S, del Zoppo GJ: Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat). Am J Pathol 1994; 144: 188-199
5. Vedder NB, Winn RK, Rice CL, Chi EY, Arfors KE, Harlan JM: A monoclonal antibody to the adherence-promoting leukocyte glycoprotem. CD18, reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits. J Clin Invest 1988; 81: 939-944
6. Weiss SJ: Tissue destruction by neutrophils. N Engl J Med 1989; 320: 365-376
7. Hallenfaeck JM, Dutka AJ: Background review and current concepts of reperfusion injury. Arch Neurol 1990; 47: 1245-1254
8. Adams D, Shaw S: Leukocyte-endothehal interactions and regulation of leukocyte migration. Lancet 1994; 343: 831-836
9. Dustin ML, Staunton DE, Springer TA: Supergene families meet in the immune system. Immunol Today 1988; 9: 213-215
10. Springer TA: Adhesion receptors of the immune system. Nature 1990; 346: 425-434
11. del Zoppo GJ, Schmid-Schönbein GW, Mori E, Copeland BR, Chang CM: Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 1991; 22: 1276-1283
12. Mon E, del Zoppo GJ, Chambers JD, Copeland BR, Arfors KE: Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons. Stroke 1992; 23: 712-718
13. Ames A, Wright RL, Kowada M, Thurston JM, Majno G: Cerebral ischemia. II. The no-reflow phenomenon. Am J Pathol 1968; 52: 437-453
14. Kochanek PM, Hallenbeck JM: Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 1992; 23: 1367-1379
15. Lindsberg PJ, Hallenbeck JM, Feuerstein G: Platelet-activating factor in stroke and brain injury. Ann Neurol 1991; 30: 117-129
16. Schmid-Schonbein GW, Engler R: Granulocytes as active participants in acute myocardial ischemia and infarction. Am J Cardiovasc Path 1986; 1: 15-29
17. Iadecola C, Zhang F, Xu S, Casey R, Ross ME: Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J Cereb Blood Flow Metab 1995; 15: 378-384
18. Entman ML, Michael L, Rossen RD, Dreyer WJ, Andersen DC, Taylor AA, Smith CW: Inflammation in the course of early myocardial ischemia. FASEB J 1991; 5: 2529-2537
19. Chen H, Chopp M, Bodzin G, Zeloga C, Carey J, Smith CW: The expression of adhesion molecules after transient focal cerebral ischemia in the rats. J Cereb Blood Flow Metab 1993; 13 (Suppl 1): S123
20. Zhang RL, Chopp M, Zaloga C, Zhang ZG, Jiang N, Gautam SC, Tang WX, Tsang W, Anderson DC, Manning AM: The temporal profiles of ICAM-1 protein and mRNA expression after transient MCA occlusion in the rat. Brain Res 1995: 682, 182-188
21. Okada Y, Copeland BR, Mori E, Tung MM, Thomas WS, del Zoppo GJ: P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion. Stroke 1994; 25: 202-211
22. Baronc FC, Wang X, Yue T-L, Clark RK, Feuerstein GF: Demonstration of increased endothelial-leukocyte adhesion molecule 1 mRNA expression in rat focal ischemic cortex using quantitative reverse transcription and polymerase chain reaction. Stroke 1995; 26: 14
23. Clark WM, Madden KP, Rothlein R, Zivin JA: Reduction of central nervous system ischemic injury in rabbits using leukocyte adhesion antibody treatment. Stroke 1991; 22: 877-883
24. Clark WM, Madden KP, Rothlein R, Zivin JA: Reduction of central nervous system ischemic injury by monoclonal antibody to intercellular adhesion molecule. J Neurosurg 1991; 75: 623-627
25. Zhang RL, Chopp M, Li Y, Zaloga C, Jiang N, Jones ML, Miyasaka M, Ward PA: Anti-ICAM-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in the rat. Neurology 1994; 44: 1747-1751
26. Chcn H, Chopp M, Zhang RL, Bodzin G, Chen Q, Rusche JR, Todd RF III: Anti-CD lib monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat. Ann Neurol 1994; 35: 458-463
27. Takcshima R, Kirsch JR, Koehlcr RC, Gomoll AW, Traystman RJ: Monoclonal leukocyte antibody does not decrease the injury of transient focal cerebral ischemia in cats. Stroke 1992; 23: 247-252
28. Soriano SG, Wang YM, Lipton SA, Gutierrez-Ramos JC, Hickey PR: 1CAM-1 knockouts are resistant to cerebral ischemia reperfusion injury. Stroke 1995; 26: 14
29. Chopp M, Zhang RL, Chen H, Li Y, Jiang N, Rusche JR: Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats. Stroke 1994; 25: 869-876
30. Lindsberg PJ, Sirén AL, Feuerstein GZ, Hallenbeck JM: Antagonism of neutrophil adherence in the deteriorating stroke model in rabbits. J Neurosurg 1995; 82: 269-277
31. Zhang RL, Chopp M, Jiang N, Tang WX, Prostak J, Manning AM, Anderson DC: Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the Wistar rat. Stroke 1995; 26: 1438-1443
32. Lindsberg PJ, Yue TL, Frerichs KU, Hallenbeck JM, Feuerstein G: Evidence for platelet-activating factor as a novel mediator in experimental stroke in rabbits. Stroke 1990; 21: 1452-1457
33. Jaeschke H, Farhood A, Bautista AP, Spolarics Z, Spitzer JJ, Smith CW: Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemiareperfusion injury in rat liver. Hepatology 1993; 17: 915-923
34. Simpson PJ. Todd RF, Mickelson JK, Fantone JC, Gallagher KP, Lee KA,-Tamura Y, Cronin M, Lucchesi BR: Sustained limitation of myocardial reperfusion injury by a monoclonal antibody that alters leukocyte function. Circulation 1990; 81: 226-237
35. Kim JS, Chopp M, Chen H, Levine SR, Carey JL, Welch KM: Adhesive glycoproteins CD11a and CD18 are upregulated in the leukocytes from patients with ischemic stroke and transient ischemic attacks. J Neurol Sci 1995; 128: 45-50
36. Lindsberg PJ, Carpén O, Paetau A, Karjalainen-Lindsberg ML. Kaste M: Endothelial ICAM- expression associated with inflammatory cell response in human ischemic stroke. Circulation 1996; 94: 939-945
37. Clark WM, Coull BM, Bnley DP, Mainolfi E, Rothlein R: Circulating intercellular adhesion molecule-1 levels and neutrophil adhesion in stroke. J Neuroimmunol 1993; 44: 123-125
38. Fassbcnder K, Mössner R, Motsch L, Kischka U, Grau A, Hennenci M: Circulating selectin- and immunoglobulin-type adhesion molecules in acute ischemic stroke. Stroke 1995; 26: 1361-1364
39. Bowes MP, Rothlein R, Fagan SC, Zivin JA: Monoclonal antibodies preventing leukocyte activation reduce experimental neurologic injury and enhance efficacy of thrombolytic therapy. Neurology 1995; 45: 815-819