Pharmacokinetic studies of the fragrance compound 1,8-cineol in humans during inhalation

Chemical Senses

Volumn 21, Issue 4, 1996, Pages 477-480

  Jager W ^a   Nasel B ^a   Nasel C ^a   Binder, R ^a   Stimpfl, T ^a   Vycudilik, W ^a   Buchbauer, G ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CINEOLE;

ABSORPTION; ADULT; AIR; ARTICLE; BLOOD LEVEL; BREATHING; FEMALE; HALF LIFE TIME; HUMAN; HUMAN EXPERIMENT; INHALATION; MALE; NORMAL HUMAN; PHARMACOKINETICS; PRIORITY JOURNAL;

EID: 0029840605     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/21.4.477     Document Type: Article

References (8)

1. Ammon, H.P.T. (1989) Phytotherapeutika in der Kneipp-Therapie. Therapiewoche, 39, 117-127.
2. Buchbauer, G., Jirovetz, L., Jäger, W., Plank, C. and Dietrich, H. (1993a) Fragrance compounds and essential oils with sedative effects upon inhalation. J. Pharm. Sci., 82, 660-664.
3. Buchbauer, G., Jirovetz, L., Czejka, M., Našel, C. and Dietrich, H. (1993b) New results in aromatherapy research. Paper presented at the 24th International Symposium on Essential Oils, July 21-24, 1993, Berlin.
4. Heinzel, G., Woloszczak, R. and Thomann, P. (1993) Top Fit Version 2.0, Pharmacokinetic and Pharmacodynamic Data Analysis System. Gustav Fischer Verlag, Stuttgart.
5. Kovar, K.A., Gropper, B., Friess, D. and Ammon, H.P.T. (1987) Blood levels of 1,8-cineol and locomotor activity of mice after inhalation and oral administration of rosemary oil. Planta Med., 53, 315-318.
6. Našel, C., Našel, B., Samec, P., Schindler, E. and Buchbauer G. (1994) Functional imaging of effects of fragrances on the human brain after prolonged inhalation. Chem. Senses, 19, 359-364.
7. Stimpfl, T., Našel, B., Našel C., Binder, R., Vycudilik, W. and Buchbauer, G. (1995) Concentration of 1,8-cineol in human blood during prolonged inhalation. Chem. Senses, 20, 349-350.
8. Wissenschaftliche Tabellen Geigy (1982) Teilband Somatometrie und Biochemie, 8th edn. Ciba-Geigy, Basel.