메뉴 건너뛰기




Volumn 17, Issue 8, 1996, Pages 717-724

Nasal administration of morphine-6-glucuronide in sheep - A pharmacokinetic study

Author keywords

chitosan; morphine 6 glucuronide; nasal; pharmacokinetics; sheep model

Indexed keywords

MORPHINE; MORPHINE 6 GLUCURONIDE;

EID: 0029840181     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199611)17:8<717::AID-BDD985>3.0.CO;2-I     Document Type: Article
Times cited : (22)

References (25)
  • 1
    • 1542768293 scopus 로고
    • Analgesic activity of morphine-6-glucuronide
    • R. Osborne, S. P. Joel, D. Trew and M. L. Slevin, Analgesic activity of morphine-6-glucuronide. Lancet, i, 828 (1988).
    • (1988) Lancet , vol.1 , pp. 828
    • Osborne, R.1    Joel, S.P.2    Trew, D.3    Slevin, M.L.4
  • 2
    • 0025190756 scopus 로고
    • Morphine and metabolic behaviour after different routes of morphine administration: Demonstration of the importance of the active metabolite morphine-6-glucuronide
    • R. J. Osborne, S. Joel, D. Trew and M. Slevin, Morphine and metabolic behaviour after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide. Clin. Pharmacol. Ther., 47, 12-19 (1990).
    • (1990) Clin. Pharmacol. Ther. , vol.47 , pp. 12-19
    • Osborne, R.J.1    Joel, S.2    Trew, D.3    Slevin, M.4
  • 3
    • 0002998410 scopus 로고
    • Morphine and its 3- and 6-glucuronides in plasma and urine during chronic oral administration in cancer patients
    • K. M. Foley and C. E. Inturrisi (Eds), Raven, New York
    • J. Sawe, Morphine and its 3- and 6-glucuronides in plasma and urine during chronic oral administration in cancer patients. In Advances in Pain Research and Therapy, K. M. Foley and C. E. Inturrisi (Eds), Raven, New York, 1986, pp. 45-55.
    • (1986) Advances in Pain Research and Therapy , pp. 45-55
    • Sawe, J.1
  • 4
    • 0028036747 scopus 로고
    • The effect of different routes of administration on the metabolism of morphine: The disposition of morphine and its metabolites after topical application
    • T. Matsuzawa, Y. Wada, M. Shimoyama, K. Nakajima, T. Seki, K. Sugibayashi and M. Shimoyama, The effect of different routes of administration on the metabolism of morphine: the disposition of morphine and its metabolites after topical application. Biopharm. Drug Disposit., 15, 665-678 (1994).
    • (1994) Biopharm. Drug Disposit. , vol.15 , pp. 665-678
    • Matsuzawa, T.1    Wada, Y.2    Shimoyama, M.3    Nakajima, K.4    Seki, T.5    Sugibayashi, K.6    Shimoyama, M.7
  • 9
    • 0025219273 scopus 로고
    • Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: Comparison with morphine
    • M. H. Hanna, S. J. Peat, M. Woodham, A. Knibb and C. Fung, Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: comparison with morphine. Br. J. Anaesth., 64, 547-550 (1990).
    • (1990) Br. J. Anaesth. , vol.64 , pp. 547-550
    • Hanna, M.H.1    Peat, S.J.2    Woodham, M.3    Knibb, A.4    Fung, C.5
  • 10
    • 9844232586 scopus 로고
    • The pharmacokinetics of morphine and morphine glucuronides in normal volunteers after four routes of administration
    • R. J. Osborne, S. P. Joel, D. Trew and M. Slevin, The pharmacokinetics of morphine and morphine glucuronides in normal volunteers after four routes of administration. Br. J. Cancer, 23, 227-228 (1986).
    • (1986) Br. J. Cancer , vol.23 , pp. 227-228
    • Osborne, R.J.1    Joel, S.P.2    Trew, D.3    Slevin, M.4
  • 11
    • 0026070941 scopus 로고
    • Disposition of morphine-6-glucuronide and morphine in healthy volunteers
    • M. H. Hanna, S. J. Peat, A. A. Knibb and C. Fung, Disposition of morphine-6-glucuronide and morphine in healthy volunteers. Br. J. Anaesth., 66, 103-107 (1991).
    • (1991) Br. J. Anaesth. , vol.66 , pp. 103-107
    • Hanna, M.H.1    Peat, S.J.2    Knibb, A.A.3    Fung, C.4
  • 12
    • 10544251111 scopus 로고    scopus 로고
    • Octanol-, chloroform-, and PGDP-water partitioning of morphine-6-glucuronide and other related opioids
    • submitted
    • A. Avdeef, D. A. Barrett, P. N. Shaw, R. D. Knaggs and S. S. Davis, Octanol-, chloroform-, and PGDP-water partitioning of morphine-6-glucuronide and other related opioids. J. Med. Chem. submitted.
    • J. Med. Chem.
    • Avdeef, A.1    Barrett, D.A.2    Shaw, P.N.3    Knaggs, R.D.4    Davis, S.S.5
  • 13
    • 0028124642 scopus 로고
    • Chitosan as a novel nasal delivery system for peptide drugs
    • L. Illum, N. F. Farraj and S. S. Davis, Chitosan as a novel nasal delivery system for peptide drugs. Pharm. Res., 11, 1186-1189 (1994).
    • (1994) Pharm. Res. , vol.11 , pp. 1186-1189
    • Illum, L.1    Farraj, N.F.2    Davis, S.S.3
  • 14
    • 10544225800 scopus 로고    scopus 로고
    • Animal models for nasal delivery
    • in press
    • L. Illum, Animal models for nasal delivery. J. Drug Targeting, in press.
    • J. Drug Targeting
    • Illum, L.1
  • 15
    • 0025026181 scopus 로고
    • Nasal administration of insulin using bioadhesive microspheres as a delivery system
    • N. F. Farraj, B. R. Johansen, S. S. Davis and L. Illum, Nasal administration of insulin using bioadhesive microspheres as a delivery system. J. Control. Rel., 13, 253-261 (1990).
    • (1990) J. Control. Rel. , vol.13 , pp. 253-261
    • Farraj, N.F.1    Johansen, B.R.2    Davis, S.S.3    Illum, L.4
  • 16
    • 0027289542 scopus 로고
    • An improved extraction method for the HPLC determination of morphine and its metabolites in plasma
    • M. Pawula, D. A. Barrett and P. N. Shaw, An improved extraction method for the HPLC determination of morphine and its metabolites in plasma. J. Pharm. Biomed. Anal., 11, 401-406 (1993).
    • (1993) J. Pharm. Biomed. Anal. , vol.11 , pp. 401-406
    • Pawula, M.1    Barrett, D.A.2    Shaw, P.N.3
  • 19
    • 0028071051 scopus 로고
    • The effect of chitosan on the permeability of monolayers of intestinal epithelial cells (CaCo-2)
    • P. Artursson, T. Lindmark, S. S. Davis and L. Illum, The effect of chitosan on the permeability of monolayers of intestinal epithelial cells (CaCo-2). Pharm. Res., 11, 1358-1361 (1994).
    • (1994) Pharm. Res. , vol.11 , pp. 1358-1361
    • Artursson, P.1    Lindmark, T.2    Davis, S.S.3    Illum, L.4
  • 20
    • 0029003181 scopus 로고    scopus 로고
    • Chitosan as a nasal delivery system: Evaluation of the effect of chitosan on mucociliary clearance rate in the frog palate model
    • in press
    • T. J. Aspden, J. Adler, S. S. Davis, Ø. Skaugrud and L. Illum, Chitosan as a nasal delivery system: evaluation of the effect of chitosan on mucociliary clearance rate in the frog palate model. Int. J. Pharm., in press.
    • Int. J. Pharm.
    • Aspden, T.J.1    Adler, J.2    Davis, S.S.3    Skaugrud, Ø.4    Illum, L.5
  • 21
    • 0342859496 scopus 로고
    • Intranasal midazolam premedication in pre-school chilren
    • N. C. T. Wilton, J. Leigh, D. Rosen and U. Pandit, Intranasal midazolam premedication in pre-school chilren. Anesth. Analg., 67, S260 (1988).
    • (1988) Anesth. Analg. , vol.67
    • Wilton, N.C.T.1    Leigh, J.2    Rosen, D.3    Pandit, U.4
  • 24
    • 0024468996 scopus 로고    scopus 로고
    • Intranasal opiates: Old route for new drugs
    • F. E. Ralley, Intranasal opiates: old route for new drugs. Can. J. Anaesth., 36, 491-493.
    • Can. J. Anaesth. , vol.36 , pp. 491-493
    • Ralley, F.E.1
  • 25
    • 0026070941 scopus 로고
    • Disposition of morphine-6 glucuronide and morphine in healthy volunteers
    • M. H. Hanna, S. J. Peat, A. A. Knibb and C. Fung, Disposition of morphine-6 glucuronide and morphine in healthy volunteers. Br. J. Anaesth., 66, 103-107 (1991).
    • (1991) Br. J. Anaesth. , vol.66 , pp. 103-107
    • Hanna, M.H.1    Peat, S.J.2    Knibb, A.A.3    Fung, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.