Inducible expression of the vaccinia virus A17L gene provides a synchronized system to monitor sorting of viral proteins during morphogenesis

Journal of Virology

Volumn 70, Issue 11, 1996, Pages 7641-7653

  Rodríguez, Dolores ^a   Risco, Cristina ^a   Rodríguez, Juan Ramón ^a   Carrascosa, José L ^a   Esteban, Mariano ^a  

^a CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ENVELOPE PROTEIN; THIOGLYCOSIDE; VIRUS PROTEIN;

ARTICLE; CELL NUCLEUS MEMBRANE; GENE EXPRESSION REGULATION; GENETIC CODE; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE; MORPHOGENESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; ROUGH ENDOPLASMIC RETICULUM; VACCINIA VIRUS; VIRION;

EID: 0029840072     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.11.7641-7653.1996     Document Type: Article

References (50)

1. Appleyard, G., A. J. Hapel, and E. A. Boulter. 1971. An antigenic différence between intracellular and extracellular rabbitpox virus. J. Gen. Virol. 13:9-17.
2. Blasco, R., and B. Moss. 1991. Extracellular vaccinia virus formation and cell-to-cell virus transmission are prevented by deletion of the gene encoding the 37,000-dalton outer envelope protein. J. Virol. 65:5910-5920.
3. Blasco, R., J. R, Sisler, and B. Moss. 1993. Dissociation of progeny vaccinia virus from the cell membrane is regulated by a viral envelope glycoprotein: effect of a point mutation in the lectin homology domain of the A34R gene. J. Virol. 67:3319-3325.
4. Boulter, E. A., and G. Appleyard. 1973. Differences between extracellular and intracellular forms of poxviruses and their implications. Prog. Med. Virol. 16:86-108.
5. Dales, S., and B. G. T. Pogo. 1981. Biology of poxviruses. Virol. Monogr. 18:54-64.
6. Dales, S., and L. Siminovitch. 1961. The development of vaccinia virus in Earles L strain cells as examined by electron microscopy. J. Biophys. Biochem. Cytol. 10:475-503.
7. Demkowicz, W. E., J.-S. Maa, and M. Esteban. 1992. Identification and characterization of vaccinia virus genes encoding proteins that are highly antigenic in animals and are immunodominant in vaccinated humans. J. Virol. 66:386-398.
8. Duncan, S. A., and G. L. Smith. 1992. Identification and characterization of an extracellular envelope glycoprotein affecting vaccinia virus egress. J. Virol. 66:1610-1621.
9. Engelstad, M., S. T. Howard, and G. L. Smith. 1992. A constitutively expressed vaccinia gene encodes a 42-kDa glycoprotein related to complement control factors that forms part of the extracellular virus envelope. Virology 188:801-810.
10. Engelstad, M., and G. L. Smith. 1993. The vaccinia virus 42-KDa envelope protein is required for the envelopment and egress of extracellular virus and for virus virulence. Virology 194:627-637.
11. Ericsson, M., S. Cudmore, S. Shuman, R. C. Condit, G. Griffiths, J. KrijnseLocker. 1995. Characterization of ts16, a temperature-sensitive mutant of vaccinia virus. J. Virol. 69:7072-7086.
12. Esteban, M. 1977. Rifampicin and vaccinia DNA. J. Virol. 21:796-801.
13. Grimley, P. M., E. N. Rosemblum, S. J. Mims, and B. Moss. 1970. Interruption by rifampicin of an early stage in vaccinia virus morphogenesis: accumulation of membranes which are precursors of virus envelopes. J. Virol. 6:519-533.
14. Ichihashi, Y., S. Matsumoto, and S. Dales. 1971. Biogenesis of poxviruses: role of A-type inclusions and host cell membranes in virus dissemination. Virology 46:507-532.
15. Isaacs, S. N., E. J. Wolffe, L. G. Payne, and B. Moss. 1992. Characterization of a vaccinia virus-encoded 42-kilodalton class 1 membrane glycoprotein component of the extracellular virus envelope. J. Virol. 66:7217-7224.
16. Kane, E. M., and S. Shuman. 1993. Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the 17 gene that encodes a virion component. J. Virol. 67:2689-2698.
17. Katz, E., and B. Moss. 1970. Formation of a vaccinia virus structural polypeptide from a higher molecular weight precursor: inhibition by rifampicin. Proc. Natl. Acad. Sci. USA 66:677-684.
18. Krinjse-Locker, J., S. Schleich, D. Rodriguez, B. Gould, E. J. Snijder, and G. Griffiths. 1996. The role of a 21-kDa viral membrane protein in the assembly of vaccinia virus from the intermediate compartment. J. Biol. Chem. 271: 14950-14958.
19. McNulty-Kowalczyk, A., and E. Paoletti. 1993. Mutations in ORF D13L and other genetic loci alter the rifampicin phenotype of vaccinia virus. Virology 194:638-646.
20. Moss, B. Poxviridae and their replication, p. 2079-2111. In B. N. Fields and D. M. Knipe (ed.), Virology, 2nd ed. Raven Press, New York.
21. Moss, B., and E. N. Rosenblum. 1973. Protein cleavage and poxvirus morphogenesis: tryptic peptide analysis of core precursors accumulated by blocking assembly with rifampicin. J. Mol. Biol. 81:267-269.
22. Moss, B., E. N. Rosenblum, and E. Katz. 1969. Rifampin: a specific inhibitor of vaccinia virus assembly. Nature (London) 224:1280-1284.
23. Nagayama, A., B. G. T. Pogo, and S. Dales. 1970. Biogenesis of vaccinia: separation of early stages from maturation by means of rifampicin. Virology 4:1039-1051.
24. Parkinson, J. E., and G. L. Smith. 1994. Vaccinia virus gene A36R encodes a Mr 43-50 K protein on the surface of extracellular enveloped virus. Virology 204:376-390.
25. Payne, L. G. 1978. Polypeptide composition of extracellular enveloped vaccinia virus. J. Virol. 27:28-37.
26. Payne, L. G. 1979. Identification of the vaccinia hemagglutinin polypeptide from a cell system yielding large amounts of extracellular enveloped virus. J. Virol. 31:147-155.
27. Payne, L. G. 1980. Significance of extracellular enveloped virus in the in vitro and in vivo dissemination of vaccinia. J. Gen. Virol. 50:89-100.
28. Payne, L. G., and K. Kristensson. 1985. Extracellular release of enveloped vaccinia virus from mouse nasal epithelial cells in vivo. J. Gen. Virol. 66: 643-646.
29. Ravanello, M. P., and D. Hruby. 1994. Conditional lethal expression of the vaccinia virus L1R myristylated protein reveals a role in virion assembly. J. Virol. 68:6401-6410.
30. Risco, C., I. M. Antón, C. Suñé, A. M. Pedregosa, J. M. Martín-Alonso, F. Parra, J. L. Carrascosa, and L. Enjuanes. 1995. Membrane protein molecules of transmissible gastroenteritis coronavirus also expose the carboxyterminal region on the external surface of the virion. J. Virol. 69:5269-5277.
31. Risco, C., L. Menéndez-Arias, T. D. Copeland, P. Pinto da Silva, and S. Ornszlan. 1995. Intracellular transport of the murine leukemia virus during acute infection of NIH 3T3 cells: nuclear import of nucleocapsid protein and integrase. J. Cell Sci. 108:3039-3050.
32. Rodriguez, D., M. Esteban, and J.-R. Rodríguez. 1995. Vaccinia virus A17L gene product is essential for an early step in virion morphogenesis. J. Virol. 69:4640-4648.
33. Rodriguez, D., J.-R. Rodríguez, and M. Esteban. 1993. The vaccinia virus 14-kilodalton fusion protein forms a stable complex with the processed protein encoded by the vaccinia virus A17L gene. J. Virol. 67:3435-3440.
34. Rodríguez, J. F., and G. L. Smith. 1990. IPTG-dependent vaccinia virus: identification of a virus protein enabling virion envelopment by Golgi membrane and egress. Nucleic Acids Res. 18:5347-5351.
35. Schmelz, M., B. Sodeik, M. Ericsson, E. J. Wolffe, H. Shida, G. Hiller, and G. Griffiths. 1994. Assembly of vaccinia virus: the second wrapping cisterna is derived from the trans Golgi network. J. Virol. 68:130-147.
36. r protein confers resistance to an inhibitor of virus envelopment and release. J. Virol. 65:3435-3442.
37. Sodeik, B., S. Cudmore, M. Ericsson, M. Esteban, E. G. Niles, and G. Griffiths. 1995. Assembly of vaccinia virus: incorporation of p14 and p32 into the membrane of the intracellular mature virus. J. Virol. 69:3560-3574.
38. Sodeik, B., R. W. Doms, M. Ericsson, G. Hiller, C. E. Machamer, W. van't Hof, G. van Meer, B. Moss, and G. Griffiths. 1993. Assembly of vaccinia virus: role of the intermediate compartment between the endoplasmic reticulum and the Golgi stacks. J. Cell Biol. 121:521-541.
39. Sodeik, B., G. Griffiths, M. Ericsson, B. Moss, and R. W. Doms. 1994. Assembly of vaccinia virus: effects of rifampin on the intracellular distribution of viral protein p65. J. Virol. 68:1103-1114.
40. Taktman, P., A. Caligiuri, S. A. Jesty, and U. Sankar. 1995. Temperaturesensitive mutants with lesions in the vaccinia virus F10 kinase undergo arrest at the earliest stage of virion morphogenesis. J. Virol. 69:6581-6587.
41. Tartaglia, J., and E. Paolelti. 1985. Physical mapping and DNA sequence analysis of the rifampin resistance locus in vaccinia virus. Virology 147:394-404.
42. VanSlyke, J. K., P. Lee, E. M. Wilson, and D. E. Hruby. 1993. Isolation and analysis of vaccinia virus previrions. Virus Genes 7:311-324.
43. Wang, S., and S. Shuman. 1995. Vaccinia virus morphogenesis is blocked by temperature-sensitive mutations in the F10 gene, which encodes protein kinase 2. J. Virol. 69:6376-6388.
44. Whitehead, S. S., and D. E. Hruby. 1994. Differential utilization of a conserved motif for the proteolytic maturation of vaccinia virus proteins. Virology 200:154-161.
45. Whitehead, S. S., and D. E. Hruby. 1994. Transcriptionally controlled transprocessing assay: putative identification of a vaccinia virus-encoded proteinase which cleaves precursor protein p25. J. Virol. 68:7603-7608.
46. Wilcock, D., and G. L. Smith. 1994. Vaccinia virus core protein VP8 is required for virus infectivity, but not for core protein processing or for INV and EEV formation. Virology 202:294-304.
47. Wolffe, E. J., S. N. Isaacs, and B. Moss. 1993. Deletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination. J. Virol. 67:4732-4741.
48. Wolffe, E. J., D. M. Moore, P. J. Peters, and B. Moss. 1996. Vaccinia virus A17L open reading frame encodes an essential component of nascent viral membranes that is required to initiate morphogenesis. J. Virol. 70:2797-2808.
49. Zhang, Y., and B. Moss. 1991. Vaccinia virus morphogenesis is interrupted when expression of the gene encoding an 11-kilodalton phosphorylated protein is prevented by the Escherichia coli lac repressor. J. Virol. 65:6101-6110.
50. Zhang, Y., and B. Moss. 1992. Immature viral envelope formation is interrupted at the same stage by lac operator-mediated repression of the vaccinia virus D13L gene and by the drug rifampicin. Virology 187:643-653.