In vivo NMR evidence for moderate glucose accumulation in human skeletal muscle during hyperglycemia

American Journal of Physiology - Endocrinology and Metabolism

Volumn 271, Issue 3 34-3, 1996, Pages

  Roussel, Ronan ^b   Velho, Gilberto ^b   Carlier, Pierre G ^b   Jouvensal, Laurence ^b   Bloch, Gilles ^a  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b NONE

Author keywords

13C nuclear magnetic resonance spectroscopy; 31P nuclear magnetic resonance spectroscopy; glucose 6 phosphate; metabolic control of flux; muscle glucose disposal

Indexed keywords

GLUCOSE 6 PHOSPHATE;

ADULT; ARTICLE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HUMAN; HUMAN EXPERIMENT; HYPERGLYCEMIA; IN VIVO STUDY; INSULIN RESISTANCE; MALE; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SKELETAL MUSCLE;

EID: 0029839993     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.271.3.e434     Document Type: Article

References (29)

1. 31P NMR measurement of glucose-6-phosphate in the rat muscle after exercise. Magn. Reson. Med. 30: 347-350, 1993.
2. Bonadonna, R. C., S. Del Prato, M. P. Saccomani, E. Bonora, G. Gulli, E. Ferrannini, D. Bier, C. Cobelli, and R. A. DeFronzo. Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes. J. Clin. Invest. 92: 486-494, 1993.
3. 31P in vivo NMR measurement of muscle glucose after exercise (Abstract). Annu. Meet. Soc. Magn. Reson. Med. 12th New York 1993, p. 28.
4. DeFronzo, R. A., R. C. Bonadonna, and E. Ferrannini. Pathogenesis of NIDDM. A balanced overview. Diabetes Care 15: 318-368, 1992.
5. DeFronzo, R. A., J. D. Tobin, and R. Andres. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 237 (Endocrinol. Metab. Gastrointest. Physiol. 6): E214-E223, 1979.
6. Fell, D. A. Metabolic control analysis: a survey of its theoretical and experimental development. Biochem. J. 286: 313-330, 1992.
7. Froguel, P., G. Velho, P. Passa, and D. Cohen. Genetic determinants of non insulin dependent diabetes mellitus: lessons learned from family studies. Diabete Metab. 19: 1-10, 1993.
8. Gibbs, E. M., J. L. Stock, S. C. McCoid, H. A. Stukenbrok, J. E. Pessin, R. W. Stevenson, A. J. Milici, and J. D. McNeish. Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4). J. Clin. Invest. 95: 1512-1518, 1995.
9. Goodyear, L. J., M. F. Hirshman, R. J. Smith, and E. S. Horton. Glucose transporter number, activity, and isoform content in plasma membranes of red and white skeletal muscle. Am. J. Physiol. 261 (Endocrinol. Metab. 24): E556-E561, 1991.
10. 13C NMR spectroscopy. Proc. Natl. Acad. Sci. USA 89: 1109-1112, 1992.
11. Harris, R. C., E. Hultman, and L. O. Nordesjo. Glycogen, glycolytic intermediates and high energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest: methods and variance of values. Scand. J. Clin. Lab. Invest. 33: 109-120, 1974.
12. Jehenson, P., and G. Bloch. Elimination of surface signals by a surface-spoiling magnetic field gradient. Theoretical optimization and application to human in vivo NMR spectroscopy. J. Magn. Reson. 94: 59-72, 1991.
13. Kacser, H., and J. A. Burns. The control of flux. Symp. Soc. Exp. Biol. 32: 65-104, 1973.
14. Katz, A., B. L. Nyomba, and C. Bogardus. No accumulation of glucose in human skeletal muscle during euglycemic hyperinsulinemia. Am. J. Physiol. 255 (Endocrinol. Metab. 18): E942-E945, 1988.
15. Katz, A., I. Raz, M. K. Spencer, R. Rising, and D. M. Mott. Hyperglycemia induces accumulation of glucose in human skeletal muscle. Am. J. Physiol. 260 (Regulatory Integrative Comp. Physiol. 29): R698-R703, 1991.
16. Kubo, K., and J. E. Foley. Rate-limiting steps for insulin-mediated glucose uptake into perfused rat hindlimb. Am. J. Physiol. 250 (Endocrinol. Metab. 13): E100-E102, 1986.
17. Morgan, C. R., and A. Lazarow. Immunoassay of insulin: two-antibody system: plasma insulin levels of normal, subdiabetic and diabetic rats. Diabetes 12: 115-126, 1963.
18. Ploug, T., H. Galbo, T. Ohkuwa, J. Tranum-Jensen, and J. Vinten. Kinetics of glucose transport in rat skeletal muscle membrane vesicles: effects of insulin and contractions. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E700-E711, 1992.
19. Ploug, T., J. Wojtaszewski, S. Kristiansen, P. Hespel, H. Galbo, and E. A. Richter. Glucose transport and transporters in muscle giant vesicles: differential effects of insulin and contractions. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E270-E278, 1993.
20. Ren, J. M., B. A. Marshall, E. A. Gulve, J. Gao, D. W. Johnson, J. O. Holloszy, and M. Mueckler. Evidence from transgenic mice that glucose transport is rate-limiting for glycogen deposition and glycolysis in skeletal muscle. J. Biol. Chem. 268: 16113-16115, 1993.
21. Ren, J.-M., B. A. Marshall, M. M. Mueckler, M. McCaleb, J. M. Amatruda, and G. I. Shulman. Overexpression of GLUT4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice. J. Clin. Invest. 95: 429-432, 1995.
22. Rothman, D. L., I. Magnusson, G. Cline, D. Gerard, C. R. Kahn, R. G. Shulman, and G. I. Shulman. Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA 92: 983-987, 1995.
23. 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus. J. Clin. Invest. 89: 1069-1075, 1992.
24. Shulman, G. I., D. L. Rothman, D. Smith, C. M. Johnson, J. B. Blair, R. G. Shulman, and R. A. DeFronzo. Mechanism of liver glycogen repletion in vivo by nuclear magnetic resonance spectroscopy. J. Clin. Invest. 76: 1229-1236, 1985.
25. Shulman, R. G., G. Bloch, and D. L. Rothman. In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis. Proc. Natl. Acad. Sci. USA 92: 8535-8542, 1995.
26. Sjøgaard, G., and B. Saltin. Extra- and intracellular water spaces in muscles of man at rest and with dynamic exercise. Am. J. Physiol. 243 (Regulatory Integrative Comp. Physiol. 12): R271-R280, 1982.
27. 13C absolute quantitation method by referencing to tissue water and fat (Abstract). Annu. Meet. Soc. Magn. Reson. 3rd Nice 1995, p. 258.
28. Yki-Järvinen, H., A. A. Young, C. Lamkin, and J. E. Foley. Kinetics of glucose disposal in whole body and across the forearm in man. J. Clin. Invest. 79: 1713-1719, 1987.
29. Ziel, F. H., N. Venkatesan, and M. B. Davidson. Glucose transport is rate limiting for skeletal muscle glucose metabolism in normal and STZ-induced diabetic rats. Diabetes 37: 885-890, 1988.