Susceptibility of plasma low- and high-density lipoproteins to oxidation in patients with severe hyperhomocysteinemia

Journal of Molecular Medicine

Volumn 74, Issue 12, 1996, Pages 771-776

  Córdoba Porras, Alfonso ^a,b,c   Sánchez Quesada, José Luis ^b   González Sastre, Francesc ^b,d   Ordóñez Llanos, Jordi ^b,d   Blanco Vaca, Francisco ^b  

^a Corporacio Sanit Inst Bioquim C ^*  (Spain)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^c Facultad de Medicina   (Colombia)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Atherosclerosis; Classical homocystinuria; Hyperhomocysteinemia; Lipoprotein oxidation; Thromboembolism; Thrombosis

Indexed keywords

CYSTEINE; HIGH DENSITY LIPOPROTEIN; HOMOCYSTEINE; LOW DENSITY LIPOPROTEIN;

ADOLESCENT; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL WALL; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LIPOPROTEIN METABOLISM; MALE; OXIDATION; RISK FACTOR; THROMBOEMBOLISM;

EID: 0029839284     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050079     Document Type: Article

References (41)

1. Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG (1995) A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA 274:1049-1057
2. Mudd SH, Levy HL, Skovby F (1989) Disorders of transulfuration. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The metabolic basis of inherited disease. McGraw-Hill, New York, pp 693-734
3. Kang S-S, Wong PWK (1996) Genetic and nongenetic factors for moderate hyperhomocyst(e)inemia. Atherosclerosis 119:135-138
4. Rosenblatt DS (1989) Inherited disorders of folate transport and metabolism. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The metabolic basis of inherited disease. McGraw-Hill, New York, pp 2049-2064
5. Malinow MR (1994) Plasma homocyst(e)ine and arterial occlusive diseases: a mini-review. Clin Chem 40:173-176
6. Holvoet P, Collen D (1994) Oxidized lipoproteins in atherosclerosis and thrombosis. FASEB J 8:1279-1284
7. Nagano Y, Arai H, Kita T (1991) High density lipoprotein loses its effect to stimulate efflux of cholesterol from foam cells after oxidative modification. Proc Natl Acad Sci USA 88:6457-6461
8. Mackness MI, Durrington PN (1995) HDL, its enzymes and its potential to influence lipid peroxidation. Atherosclerosis 115:243-253
9. Parthasarathy S, Santanan N (1994) Mechanisms of oxidation, antioxidants, and atherosclerosis. Curr Opin Lipidol 5:371-375
10. Saez G, Thornalley PJ, Hill PJ, Hems HAO, Hems R, Bannister JV (1982) The production of free radicals during the auto oxidation of cysteine and their effect on isolated rat hepatocytes. Biochim Biophys Acta 719:24-31
11. Heinecke JW, Rosen H, Suzuki LA, Chait A (1987) The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells. J Biol Chem 262:10098-10103
12. Parthasarathy S (1987) Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor. Biochim Biophys Acta 917:337-340
13. Heinecke JW, Kawamura M, Suzuki L, Chait A (1993) Oxidation of low density lipoprotein by thiols: superoxide-dependent and -independent mechanisms. J Lipid Res 34:2051-2061
14. Sparrow CP, Olszewski J (1993) Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions. J Lipid Res 34:1219-1228
15. Wood JL, Graham A (1995) Structural requirements for oxidation of low-density lipoproteins by thiols. FEBS Letters 366:75-80
16. Yagi K. Lipid peroxides and human diseases (1987) Chem Phys Lipids 45:337-351
17. Andrews B, Burnand K, Paganga G, Browse N, Rice-Evans C, Sommerville K, Leake D, Taub N (1995) Oxidisahility of low-density lipoproteins in patients with carotid or femoral artery atherosclerosis. Atherosclerosis 112:77-84
18. Sanderson KJ, van Rij AM, Wade CR, Sutherland WHF (1995) Lipid peroxidation of circulating low density lipoproteins with age, smoking and in peripheral vascular disease. Atherosclerosis 118:45-51
19. Regnström J, Nilsson J, Tornvall P, Landou C, Hamsten A (1992) Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet 339:1183-1186
20. Holvoet P, Perez G, Zhao Z, Brouwers E, Bernar H, Collen D (1995) Malondialdehyde-modified low density lipoproteins in patients with atherosclerotic disease. J Clin Invest 95:2611-2619
21. Andersson A, Lindgren A, Hultberg B (1995) Effect of thiol oxidation and thiol export from erythrocytes on determination of redox status of homocysteine and other thiols in plasma from healthy subjects and patients with cerebral infarction. Clin Chem 41:361-366
22. Hyland K, Bottiglieri T (1992) Measurement of total plasma and cerebrospinal fluid homocysteine by fluorescence following high-performance liquid chromatography and precolumn derivatization with ortho-phthaldialdehyde. J Chromatogr 579: 55-62
23. Cohen SA, Bidlingmeyer BA, Tarvin TL (1986) PITC derivatives in amino acid analysis. Nature 320:769-770
24. Havel RJ, Eder HA, Bragdon JH (1955) The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34:1345-1353
25. Sánchez-Quesada JL, Homs-Serradesanferm R, Serrat-Serrat J, Serra-Grima JR, González-Sastre F, Ordóñez-Llanos J (1995) Increase of LDL susceptibility to oxidation occurring after intense, long duration acrobic exercise. Atherosclerosis 118:297-305
26. Esterbauer H, Striegl G, Puhl H, Rothender M (1989) Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Rad Res Common 6:67-75
27. Fontanals-Ferrer N, Serrat-Serrat J, Sorribas-Vivas A, González-García C, González-Sastre F, Gómez-Gerique JA (1988) Quick method for determining lipoproteins, including those of intermediate density, in serum. Clin Chem 34:1753-1757
28. Serrat-Serrat J, Ordóñez-Llanos J, Serra-Grima R, Gómez-Gerique JA, Pellicer-Thoma E, Payés-Romero A, González-Sastre F (1993) Marathon runners presented lower serum eholesteryl ester transfer activity than sedentary subjects. Atherosclerosis 101:43-49
29. Lavy A, Brook GJ, Dankner G, Amotz AB, Aviram M (1991) Enhanced in vitro oxidation of plasma lipoproteins derived from hypercholesterolemic patients. Metabolism 40:794-799
30. 100. Arterioscler Thromb 14:489-493
31. Mansoor MA, Ueland PM, Aarsland A, Svardal AM (1993) Redox status and protein binding of plasma homocysteine and other aminothiols in patients with homocystinuria. Metabolism 42:1481-1485
32. Gutteridge JMC, Halliwell B (1990) The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem Sci 15:129-134
33. Blom HJ, Engelen DPE, Boers GHJ, Stadhouders AM, Sengers RCA, de Abreu R, TePoele-Pothoff MTWB, Trijbels JMF (1992) Lipid peroxidation in homocysteinaemia. J Inherit Metab Dis 15:419-422
34. Dudman NPB, Wilcken DEL, Stocker R (1993) Circulating lipid hydroperoxide levels in human hyperhomocysteinemia. Relevance to development of atherosclerosis. Arterioscler Thromb 13:512-516
35. Steinberg D, Parthasarathy S, Carew TE, Khoo J, Witzum JL, Beyond cholesterol (1989) Modifications of low-density lipoproteins that increase their atherogenicity. New Engl J Med 320:915-924
36. Tribble DE (1995) Lipoprotein oxidation in dyslipidemia: insights into general mechanisms affecting lipoprotein oxidative behavior. Curr Opin Lipidol 6:196-208
37. Blom HJ, Kleinveld HA, Boers GHJ, Demacker PNM, HakLemmers HLM, Te Poele-Pothoff MTWB, Trijbels JMF (1995) Lipid peroxidation and suceptibility of low-density lipoprotein to vitro oxidation in hyperhomocysteinemia. Eur J Clin Invest 25:149-154
38. Wicken DEL, Dudman NPB (1992) Homocystinuria and atherosclerosis. In: Lusis AJ, Rotter JI, Sparkes RS (eds) Genetic factors in atherosclerosis: candidate genes and processes. Karger. Basel, pp 311-323
39. Jones BG, Rose FA, Tudball N (1994) Lipid peroxidation and homocysteine induced toxicity. Atherosclerosis 105:165-170
40. Frei B, Stocker R, Ames BN (1988) Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci USA 9748-9752
41. Santanan N, Parthasarathy S (1995) Cellular cysteine does not contribute to the initiation of LDL oxidation. J Lipid Res 36:2203-2211