Contrasting effects of IL-4, IL-10 and corticosteroids on RANTES production by human monocytes

International Immunology

Volumn 8, Issue 10, 1996, Pages 1587-1594

  Marfaing Koka, Anne ^a   Maravic, Milka ^a   Humbert, Marc ^a   Galanaud, Pierre ^a   Emilie, Dominique ^a  

^a INSERM   (France)

Author keywords

Allergy; Chemokine; Delayed type hypersensitivity reaction; Inflammation; Reactive oxygen intermediates; T(h)2 type cytokines

Indexed keywords

ACETYLCYSTEINE; INTERLEUKIN 10; INTERLEUKIN 4; RANTES; TRANSFORMING GROWTH FACTOR ALPHA;

ALLERGIC REACTION; ARTICLE; HUMAN; HUMAN CELL; HYPERSENSITIVITY REACTION; MACROPHAGE; MACROPHAGE FUNCTION; MONOCYTE; PRIORITY JOURNAL;

ACETYLCYSTEINE; ADRENAL CORTEX HORMONES; CELLS, CULTURED; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; MONOCYTES; RANTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029838835     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.10.1587     Document Type: Article

References (80)

1. Schall, T. J., Jongstra, J, Dyer B. J., Jorgensen, J., Clayberger, C., Davis, M. M. and Krensky, A. M. 1988. A human T cell-specific molecule is a member of a new gene family. J. Immunol. 141:1018.
2. Taub, D. D. and Oppenheim, J. J. 1994. Chemokines, inflammation and the immune system. Therapeutic Immunol. 1: 229.
3. Ben-Baruch, A., Michiel, D. F. and Oppenheim, J. J. 1995. Signals and receptors involved in recruitment of inflammatory cells. J. Biol. Chem. 270:11703.
4. Schall, T. J., Bacon, K., Toy, K. J. and Goeddel, D. V. 1990. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347:669.
5. Kuna, P., Reddigari, S. R., Schall, T. J., Rucinski, D., Viksman, M. Y. and Kaplan, A. P. 1992. RANTES, a monocyte and T lymphocyte chemotactic cytokine releases histamine from human basophils. J. Immunol. 149:636.
6. Kameyoshi, Y., Dorschner, A., Mallet, A. I., Christophers, E. and Schroder, J. M. 1992. Cytokine RANTES released by thrombin- stimulated platelets is a potent attractant for human eosinophils. J. Exp. Med. 176:587.
7. Rot, A., Krieger, M., Brunner, T., Bischoff, S. C., Schall, T. J. and Dahinden, C. A. 1992. RANTES and macrophage inflammatory protein 1α induce the migration and activation of normal human eosinophil granulocytes. J. Exp. Med. 176:1489.
8. Alam, R., Stafford, S., Forsythe, P., Harrison, R., Faubion, D., Lett- Brown, M. A. and Grant, J. A. 1993. RANTES is a chemotactic and activating factor for human eosinophils. J. Immunol. 150:3442.
9. Ebisawa, M., Yamada, T., Bickel, C., Klunk, D. and Schleimer, R. P. 1994. Eosinophil transendothelial migration induced by cytokines. III. Effect of the chemokine RANTES. J. Immunol. 153:2153.
10. Devergne, O., Marfaing-Koka, A., Schall, T. J., Leger-Ravet, M. B., Sadick, M., Peuchmaur, M., Crevon, M. C., Kim, T., Galanaud, P. and Emilie, D. 1994. Production of the RANTES chemokine in delayed-type hypersensitivity reactions: involvement of macrophages and endothelial cells. J. Exp. Med. 179:1689.
11. Williams, G. T. and Williams, W. J. 1983. Granulomatous inflammation - a review. J. Clin. Pathol. 36:723.
12. Dannenberg, A. M. 1991. Delayed-type hypersensitivity and cell- mediated immunity in the pathogenesis of tuberculosis. Immunol. Today. 12:228.
13. Kindler, V., Sappino, A. P., Grau, G. E., Piguet, P. F. and Vassalli, P. 1989. The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell 56:731.
14. Yamamura, M., Uyemura, K., Deans, R. J., Weinberg, K., Rea, T. H., Bloom, B. R. and Modlin, R. L. 1991. Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 254:277.
15. Yamamura, M., Wang, X. H., Ohmen, J. D., Uyemura, K., Rea, T. H., Bloom, B. R. and Modlin, R. L., 1992. Cytokine patterns of immunologically mediated tissue damage. J. Immunol. 149:1470.
16. h1-type cells (IFN-γ, IL2) in classical delayed-type (tuberculin) hypersensitivity reactions in human skin. J. Immunol. 148:2058.
17. Devergne, O., Emilie, D., Peuchmaur, M., Crevon, M. C., D'Agay, M. F. and Galanaud, P. 1992. Production of cytokines in sarcoid lymph nodes: preferential expression of interleukin 1β and Interferon γ genes. Hum. Pathol. 23:317.
18. Marfaing-Koka, A., Devergne, O., Gorgone, G., Portier, A., Schall, T. J., Galanaud, P. and Emilie, D. 1995. Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-γ plus TNF-α and inhibition by IL4 and IL13. J. Immunol. 154:1870.
19. Sadick, M. D., Heinzel, B. J., Holaday, R. T., Pu, R. T., Dawkins, R. S. and Locksley, R. M. 1990. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody: evidence for a T cell- dependent, interferon γ independent mechanism. J. Exp. Med. 171:115.
20. Powrie, F., Menon, S. and Coffman, R. L. 1993. Interleukin 4 and interleukin 10 synergize to inhibit cell-mediated immunity in vivo. Eur J. Immunol. 23:3043.
21. Li, L., Elliott, J. F. and Mosmann, T. R. 1994. IL10 inhibits cytokine production, vascular leakage, and swelling during T helper1 cell- induced delayed-type hypersensitivity. J. Immunol. 153:3967.
22. Pinkston, P., Saltini, C., Muller-Quernhaim, J. and Crystal, R. G. 1987. Corticosteroid therapy suppresses spontaneous interleukin 2 release and spontaneous proliferation of lung T lymphocytes of patients with active pulmonary sarcoidosis. J. Immunol. 139:755.
23. Baggiolini, M. and Dahinden, C. A. 1994. CC chemokines in allergic inflammation. Immunol. Today 15:127.
24. Ying, S., Taborda-Barata, L., Meng, Q., Humbert, M. and Kay, A. B. 1995. The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein 3 and RANTES in the skin of human atopic subjects: relationship to eosinophil, T cell and macrophage recruitment. J. Exp. Med. 181:2153.
25. Humbert, M., Ying S., Corrigan, C., Menz, G., Barkans, J., Pfister, R., Meng, Q., Van Damme, J., Opdenakker, G., Durham, S. R. and Kay, A. B. 1996. Bronchial mucosa expression of the gene encoding CC chemokines RANTES and MCP-3 in symptomatic atopic and non atopic asthmatics: relationship to the eosinophil- active cytokines IL-5, GM-CSF, IL-3. Am. J. Respir Cell. Mol. Biol., in press.
26. Wahl, L. M., Katona, I. M., Wilder, R. L., Winter C. C., Haraoui, B., Sher, I. and Wahl, S. M. 1984. Isolation of human monocytes cell subsets by counterflow centrifugal elutriation (CEE). I. Characterisation of B lymphocyte, T lymphocyte, and monocyte- enriched fraction by flow cytometric analysis. Cell. Immunol. 85:373.
27. Peuchmaur, M., Emilie, D., Crevon, M. C., Solal-Celigny, P., Maillot M. C., Lemaigre, G. and Galanaud, P. 1990. IL-2 mRNA expression in Tac-positive malignant lymphomas. Am. J. Pathol. 136:383.
28. Collart, M. A., Belin, D., Vassalli, J. D., De Kossodo, S. and Vassalli, P. 1986. Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin1, and urokinase genes, which are controlled by short-lived repressors. J. Exp. Med. 164:2113.
29. Hart, P. H., Whitty, G. A., Piccoli, D. S. and Hamilton, J. A. 1989. Control by IFN-gamma and PGE2 of TNF-alpha and IL1 production by human monocyte Immunology 66:376.
30. Farrar, M. A. and Schreider, R. D. 1993. The molecular cell biology of interferon γ and its receptor. Annu. Rev. Immunol. 11:571
31. Meyer, R., Hatada, E. N., Hohmann, H. P., Haiker, M., Bartsch, C., Rothlisberger, U., Lahm, H. W., Schlaeger, E. J., Van Loon, A. P. G. M. and Scheidereit, C. 1991. Cloning of the DNA-binding subunit of human nuclear factor κB: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor α. Proc. Natl Acad. Sci. USA 88:966.
32. Schutze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K. and Kronke M. 1992. TNF- activation NF-κB by phosphatidylcholine-specific phospholipase C-induced 'acidic' sphingo- myelin breakdown. Cell 71:765.
33. Schulze-Osthoff, K., Bakker, A. C., Vanhaesebroeck, B., Beyaert, R., Jacob, W. A. and Fiers, W. 1992. Cytotoxic activity of tumor necrosis factor is mediated by early damage to mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. J. Biol. Chem. 267:5317.
34. Schulze-Osthoff, K., Beyaert, R., Vandervoorde, V., Haegeman, G. and Fiers, W. 1993. Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene induction effects of TNF-α. EMBO J. 12:3095.
35. Schreck, R., Rieber, P. and Baeuerle, P. A. 1991. Reactive oxygen intermediates as apparently widely used messengers in the activation of NF-κB transcription factor and HIV-1. EMBO J. 10:2247.
36. Los, M., Schenk, H., Hexel, K., Baeuerle, P. A., Droge, W. and Schulze-Osthoff, K. 1995. IL-2 gene expression and NF-κB activation through CD28 requires reactive oxygen production by 5-lipoxygenase. EMBO J. 14:3731.
37. 2 and antioxidants have opposite effects on activation of NFkB and AP1 in intact cells: AP1 as secondary antioxidant-responsive factor. EMBO J. 12:2005.
38. Nelson, P. J., Kim, H. T., Manning, W. C., Goralski, T J. and Krensky, A. M. 1993. Genomic organization and transcriptional regulation of the RANTES chemokine gene. J. Immunol. 151:2601.
39. Yasumoto, K., Okamoto, S. I., Makaida, N., Murakami, S., Mai, M. and Matsushima, K. 1993. Tumor necrosis factor α and interferon γ synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP1 and NF-κB like binding sites of the interleukin 8 gene. J. Biol. Chem. 267:22506.
40. Ohomori, Y. and Hamilton, T. A. 1995. The interferon-stimulated response element and a κB site mediate synergistic induction of murine IL10 gene transcription by IFN-γ and TNF-α. J. Immunol. 154:5235.
41. Mehindate, K., al-Daccak, R., Schall, T. J. and Mourad, W. 1994. Induction of chemokine gene expression by major histocompatibility complex class II ligands in human fibroblast- like synoviocytes. Differential regulation by interleukin 4 and dexamethasone. J. Biol. Chem. 269:32063.
42. Gessani, S., McCandless, S. and Baglioni, C. 1988. The glucocorticoid dexamethasone inhibits synthesis of interferon by decreasing the level of its mRNA. J. Biol. Chem. 263:7454.
43. Zuckerman, S. H., Shellhaas, J. and Butler, L. D. 1989. Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary- adrenal axis. Eur. J. Immunol. 19:301
44. Han, J., Thompson, P. and Beutler, B. 1990. Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway. J. Exp. Med. 172:391.
45. Moreira, A. L., Sampaio, E. P., Zmuidzinas, A., Frindt, P., Smith, K. A. and Kaplan, G. 1993. Thalidomide exerts its inhibitory action on tumor necrosis factor by enhancing rnRNA degradation. J. Exp. Med. 177:1675.
46. Ray, A. and Prefontaine, K. E. 1994. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 91:752
47. Mukaida, N., Morita, M., Ishikawa, Y., Rice, N., Okamoto, S., Kasahara, T. and Matsushima, K. 1994. A novel mechanism of glucocorticoid-mediated gene repression. NF-κB is target of glucocorticoid-mediated interleukin 8 gene expression. J. Biol. Chem. 269:13289.
48. Peters-Golden, M. and Thebert, P. 1987. Inhibition by methyl- prednisolone of zymosan-induced leukotriene synthesis in alveolar macrophages. Am. Rev. Respir. Dis. 135:1020.
49. Sironi, M., Munoz, C., Pollicino, T., Siboni, A., Sciacca, F. L., Bernasconi, S., Vecchi, A., Colotta, F. and Mantovani, A. 1993. Divergent effect of interleukin-10 on cytokine production by mononuclear phagocytes and endothelial cells. Eur. J. Immunol. 23:2692.
50. De Waal Malefyt, R., Abrams, J., Bennett, B., Fidgor, C. G. and De Vries, J. E. 1991. Interleukin 10 inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL10 produced by monocyte. J. Exp. Med. 174:1209.
51. Bogdan, C. Vodovotz, Y. and Nathan, C. 1991. Macrophage deactivation by interleukin 10. J. Exp. Med. 174:1549.
52. Fiorentino, D. F., Zlotnik, A., Mosmann, T. R., Howard, M. and O'Garra, A. 1991. IL10 inhibits cytokine production by activated macrophages. J. Immunol. 147:3815
53. Oswald, I. P., Wynn, T. A., Sher, A. and James, S. L. 1992. Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor a required as a costimulatory factor for Interferon γ induced activation. Proc. Natl Acad. Sci. USA 89:8676.
54. Pradier, O., Gerard, C., Delvaux, A., Lybin, M., Abramowicz, D., Capel, P., Velu, T. and Goldman, M. 1993. Interleukin 10 inhibits the induction of monocyte procoagulant activity by bacterial lipopolysaccharide. Eur. J. Immunol. 23:2700.
55. Willems, F., Marchant, A., Delville, J. P., Gerard, C., Delvaux, A., Velu, T., De Boer, M. and Goldman, M. 1994. Interleukin 10 inhibits B7 and intercellular adhesion molecule-1 on human monocytes. Eur. J. Immunol. 24:1007.
56. Kambayashi, T., Alexander, H. R., Fong, M. and Strassmann, G. 1995. Potential involvement of IL10 in suppressing tumor- associated macrophages. J. Immunol. 154:3383.
57. Essner, R., Rhoades, K., McBride, W. H., Morton, D. L. and Economou, J. S. 1989. IL4 down-regulates IL1 and TNF-α gene expression in human monocytes. J. Immunol. 142:3857.
58. Standiford, T. J., Strieter, R. M., Chensue, S. W., Westwick, J., Kasahara, K. and Kunkel, S. L. 1990. IL4 inhibits the expression of IL8 from stimulated human monocytes. J. Immunol. 145:1435.
59. Te Velde, A. A., Huijbens, R. J. F., Heije, K., De Vries, J. E. and Fidgor, C. G. 1990. Interleukin 4 inhibits secretion of IL1β, TNF-α, and IL6 by human monocytes. Blood 76:1392.
60. Deng, W., Ohmori, Y. and Hamilton, T. A. 1994. Mechanisms of IL4-mediated suppression of IP10 gene expression in murine macrophages. J. Immunol. 153:2130.
61. 2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-γ . J. Immunol. 143:3020.
62. Te Velde, A. A., Klomp, J. P. G., Yard, B. A., De Vries, J. E. and Fidgor, C. G. 1988. Modulation of phenotypic and functional properties of human peripheral blood monocytes by IL-4. J. Immunol. 140:1548.
63. Crawford, R. M., Finbloom, D. S., Ohara, J., Paul, W. E. and Meltzer, M. S. 1987. B cell stimulatory factor-1 (interleukin 4) activates macrophages for increased tumoricidal activity and expression of 1a antigens. J. Immunol. 139:135.
64. Zlotnik, A., Fischer, M., Roehm, N. and Zipori D. 1987. Evidence for effects of interleukin 4 on macrophages: enhancement of antigen presenting ability of bone marrow-derived macrophages. J. Immunol. 138:4275.
65. Aiello, F. B., Longo, D. L., Overton, R., Takacs, L. and Durum, S. K. 1990. A role for cytokines in antigen presentation: IL-1 and IL-4 induce accessory functions of antigen-presenting cells. J. Immunol. 144:2572.
66. Vannier, E., Miller, L. C. and Dinarello, C. A. 1992. Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. Proc. Natl Acad. Sci. USA 89:4076.
67. Ferrajoli, A., Talpaz, M., Ordonez, N. G., Stanley, E. R., Hirsch- Ginsberg, C., Zipf, T. F., Wetzler, M., Kurzrock, R. and Estrov, Z. 1994. Interleukin 4 alters human bone marrow stroma and modulates its interaction with hematopoietic progenitors. Stem Cells Dayt. 12:638.
68. Bradding, P., Roberts, J. A., Britten, K. M., Montefort, S., Djukanovic, R., Mueller, R., Heusser, C. H., Howarth, P. H. and Holgate, S. T. 1994. Interleukin-4, -5, -6 and tumor necrosis factor-α in normal and asthmatic airways: evidence for human mast cells as a source of these cytokines. Am. J. Respir. Cell Mol. Biol. 10:471.
69. Gordon, J. R. and Galli, S. J. 1990. Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin. Nature 346:274.
70. Ying, S., Robinson D., Varney V., Meng Q., Tsicopoulos A., Moqbel R., Durham, S. R., Kay, A. B. and Hamid, Q. 1991. TNF-alpha mRNA expression in allergic inflammation. Clin. Exp. Allergy 21:745.
71. Robinson, D. S., Hamid, Q., Ying, A., Tsicopoulos, J., Barkans, J., Bentley, A. M., Corrigan, C., Durham, S. R. and Kay, A. B. 1992. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med 326:298.
72. Nonaka, M., Nonaka, R., Wooley, K., Adelroth, E., Miura, K., Okhawara, Y., Glibetic, M., Nakano, K., O'Byrne, P., Dolovich, J. and Jordana, M. 1995. Distinct immunohistochemichal localization of IL-4 in inflamed airway tissues: IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils. J. Immunol. 155:3234.
73. h1 type (IL-2 and IFN-gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatics and normal controls. Am. J. Respir. Cell. Mol. Biol. 21:477.
74. Lukacs, N. W., Strieter, R. M., Chensue, S. W., Widmer, M. and Kunkel, S. L. 1995 TNF-α mediates recruitment of neutrophils and eosinophils during airway inflammation. J. Immunol. 154:5411.
75. Berg, D. J., Leach, M. W., Kuhn, R., Rajewsky, K., Muller, W., Davidson, N. J. and Rennick, D. 1995. Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J. Exp. Med. 182:99.
76. Ferguson, T. A., Dube, P. and Griffith, T. S. 1994. Regulation of contact hypersensitivity by interleukin 10. J. Exp. Med. 179:1597.
77. Wang, P., Wu, P., Siegel, M. I., Egan, R. W. and Billah M. M. 1995. Interleukin 10 inhibits nuclear factor kB activation in human monocytes. J. Biol. Chem. 270:9558.
78. Yousefi, S., Hemmann, S., Weber, M., Holzer, C., Hartung, K., Blaser, K. and Simon, H. U. 1995. IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma. J. Immunol. 154:5481.
79. Schweizer, R. C., Welmers, B. A. C., Raaijmakers, J. A. M., Zanen, P., Lammers, J. W. J. and Koenderman, L. 1994. RANTES-and interleukin 8-induced responses in normal human eosinophils: effects of priming with interleukin 5. Blood 83:3697.
80. Taub, D. D., Lloyd, A. R., Conlon, K., Wang, J M., Ortaldo, J. R., Harada, A., Matsushima, K., Kelvin, D. J. and Oppenheim, J. J. 1993. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes cell adhesion to endothelial cells. J. Exp. Med. 177:1809.