Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons

Journal of Physiology

Volumn 494, Issue 2, 1996, Pages 465-477

  Zorumski, Charles F ^a   Mennerick, Steven ^a   Que, Jian ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYASPARTIC ACID; AGGLUTININ; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; CALCIUM ION; CYCLOTHIAZIDE; GLUTAMIC ACID; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PERTUSSIS TOXIN; POSTSYNAPTIC RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; HIPPOCAMPUS; MEMBRANE CURRENT; NERVE CELL CULTURE; NERVE EXCITABILITY; NEWBORN; NONHUMAN; PATCH CLAMP; POSTSYNAPTIC MEMBRANE; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SYNAPTIC TRANSMISSION; WHEAT GERM;

EID: 0029838753     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021506     Document Type: Article

References (37)

1. AMBROS-INGERSON, J. & LYNCH, G. (1993). Channel gating kinetics and synaptic efficacy: hypothesis for expression of long-term potentiation. Proceedings of the National Academy Sciences of the USA 90, 7903-7907.
2. BASKYS, A. & MALENKA, R. C. (1991). Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus. Journal of Physiology 444, 687-701.
3. BENVENISITE, H., DREJER, J., SCHOUSBOE, A. & DIEMER, N. H. (1984). Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. Journal of Neurochemistry 43, 1369-1374.
4. BOUVIER, M., SZATKOWSKI, M., AMATO, A. & ATTWELL, D. (1992). The glial cell glutamate uptake carrier countertransports pH-changing anions. Nature 360, 471-474.
5. BURGER, P. M., MEHL, E., CAMERON, P. L., MAYCOX, P. R., BAUMERT, M., LOTTSPEICH, F., DE CAMILLI, P. & JAHN, R. (1989). Synaptic vesicles immunoisolated from rat cerebral cortex contain high levels of glutamate. Neuron 3, 715-720.
6. CLARK, G. D., CLIFFORD, D. B. & ZORUMSKI, C. F. (1990). The effect of agonist concentration, membrane voltage, and calcium on N-methyl-D-aspartate receptor desensitization. Neuroscience 39, 787-797.
7. COAN, E. J., IRVING, A. J. & COLLINGRIDE, G. L. (1989). Low-frequency activation of the NMDA receptor system can prevent the induction of LTP. Neuroscience Letters 105, 205-210.
8. COLQUHOUN, D., JONAS, P. & SAKMANN, B. (1992). Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices. Journal of Physiology 458, 261-287.
9. DANBOLT, N. C. (1994). The high affinity uptake system for excitatory amino acids in the brain. Progress in Neurobiology 44, 377-396.
10. DIAMOND, J. S. & JAHR, C. E. (1995). Asynchronous release of synaptic vesicles determines the time course of AMPA receptor-mediated EPSC. Neuron 15, 1097-1107.
11. FORSYTHE, I. D. & CLEMENTS, J. D. (1990). Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones. Journal of Physiology 429, 1-16.
12. HUANG, Y.-Y., COLINO, A., SELIG, D. K. & MALENKA, R. C. (1992). The influence of prior synaptic activity on the induction of long-term potentiation. Science 255, 730-733.
13. JONAS, P., MAJOR, G. & SAKMANN, B. (1993). Quantal components of unitary EPSCs at the mossy fibre synapse on CA3 pyramidal cells of rat hippocampus. Journal of Physiology 472, 615-663.
14. LEGENDRE, P., ROSENMUND, C. & WESTBROOK, G. L. (1993). Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium. Journal of Neuroscience 13, 674-684.
15. LERMA, J., HERRANZ, A. S., HERRARAS, O., ABRAIRA, V. & MARTIN DEL Rio, R. (1986). In vivo determination of extracellular concentration of amino acids in the rat hippocampus. A method based on brain dialysis and computerized analysis, Brain Research 384, 145-155.
16. LIN, F. & STEVENS, C. F. (1994). Both open and closed NMDA receptor channels desensitize. Journal of Neuroscience 14, 2153-2160.
17. MAKI, R., ROBINSON, M. B. & DICHTER, M. A. (1994). The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate depresses excitatory synaptic transmission via a presynaptic mechanism in cultured hippocampal neurons. Journal of Neuroscience 14, 6754-6762.
18. MANZONI, O. J., MANABE, T. & NICOLL, R. A. (1994). Release of adenosine by activation of NMDA receptors in the hippocampus. Science 265, 2098-2101.
19. MENNERICK, S., BENZ, A. & ZORUMSKI, C. F. (1996). Components of glial responses to exogenous and synaptic glutamate in rat hippocampal microcultures. Journal of Neuroscience 16, 55-64.
20. MENNERICK, S. & ZORUMSKI, C. F. (1994). Glial contributions to excitatory neurotransmission in cultured hippocampal cells. Nature 368, 59-62.
21. MENNERICK, S. & ZORUMSKI, C. F. (1995a). Presynaptic influence upon the time course of fast excitatory synaptic currents in cultured hippocampal cells. Journal of Neuroscience 15, 3178-3192.
22. MENNERICK, S. & ZORUMSKI, C. F. (1995b). Paired-pulse modulation of fast excitatory synaptic currents in microcultures of rat hippocampal neurones. Journal of Physiology 488, 85-101.
23. MENNERICK, S, & ZORUMSKI, C. F. (1996). Postsynaptic modulation of NMDA synaptic currents in rat hippocampal microcultures by paired-pulse stimulation. Journal of Physiology 490, 405-417.
24. PATNEAU, D. K. & MAYER, M. L. (1990). Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors. Journal of Neuroscience 10, 2385-2399.
25. PERKEL, D. J. & NICOLL., R. A. (1994). Evidence for all-or-none regulation of neu neurotransmitter release: implications for long-term potentiation. Journal of Physiology 471, 481-500.
26. ROSENMUND, C., FELTZ, A. & WESTBROOK, G. L. (1995). Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons. Journal of Neurophysiology 73, 427-430.
27. SAH, P., HESTRIN, S. & NICOLL, R. A. (1989). Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons. Science 246, 815-818.
28. SATHER, W., DIEUDONNE, S., MACDONALD, J. F. & ASCHER, P. (1992). Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones. Journal of Physiology 450, 643-672.
29. SEGAL, M. M. & FURSHPAN, E. J. (1990). Epileptiform activity in microcultures containing small numbers of hippocampal neurons. Journal of Neurophysiology 64, 1390-1399.
30. SHARP, R. L., MAYNE, N. G. & BURNETT, J. P. (1994). Cyclothiazide differentially modulates human metabotropic glutamate receptors linked to phosphoinositide hydrolysis stimulation in oocytes, European Journal of Pharmacology 269, R5-7.
31. THIO, L. L., CLARK, G. D., CLIFFORD, D. B. & ZORUMSKI, C. F. (1992). Wheat germ agglutinin enhances EPSCs in cultured postnatal rat hippocampal neurons by blocking ionotropic quisqualate receptor desensitization. Journal of Neurophysiology 68, 1930-1938.
32. TONG, G. & JAHR, C. E. (1994a). Multivesicular release from excitatory synapses of cultured hippocampal neurons. Neuron 12, 51-59.
33. TONG, G. & JAHR, C. E. (1994b). Block of glutamate transporters potentiates postsynaptic excitation. Neuron 13, 1195-1203.
34. TONG, G. SHEPHERD, D. & JAHR, C. E. (1995). Synaptic desensitization of NMDA receptors by calcineurin. Science 267, 1510-1512.
35. TRUSSELL, L. O. & FISCHBACH, G. D. (1989). Glutamate receptor desensitization and its role in synaptic transmission. Neuron 3, 209-218.
36. VYKLICKY, L. JR, PATNEAU, D. K. & MAYER, M. L. (1991). Modulation of excitatory synaptic transmission by drugs that reduce desensitization at AMPA/kainate receptors. Neuron 7, 971-984.
37. YAMADA, K. A. & TANG, C.-M. (1993). Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents. Journal of Neuroscience 13, 3904-3915.