-
1
-
-
0017162163
-
Proposals for the classification of the acute leukemias
-
Bennett, J. M., Calovsky, D., Daniel, M. T., Flandrin, G., Galton, D., Gralnick, M., and Sultan, C. (1976) Proposals for the classification of the acute leukemias. Br. J. Haematol. 33, 451-458
-
(1976)
Br. J. Haematol.
, vol.33
, pp. 451-458
-
-
Bennett, J.M.1
Calovsky, D.2
Daniel, M.T.3
Flandrin, G.4
Galton, D.5
Gralnick, M.6
Sultan, C.7
-
2
-
-
0021345113
-
Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia
-
Larson, R. A., Kondo, K., Vardiman, J. W., Butler, A. R. E., Colomb, H. M., and Rowley, J. D. (1984) Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia. Am. J. Med. 76, 827-841
-
(1984)
Am. J. Med.
, vol.76
, pp. 827-841
-
-
Larson, R.A.1
Kondo, K.2
Vardiman, J.W.3
Butler, A.R.E.4
Colomb, H.M.5
Rowley, J.D.6
-
3
-
-
0025875679
-
The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
-
de Thé, H., Lavau, C., Marchio, A., Chomienne, C., Degos, L., and Dejean, A. (1991) The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 66, 675-684
-
(1991)
Cell
, vol.66
, pp. 675-684
-
-
Thé, H.1
Lavau, C.2
Marchio, A.3
Chomienne, C.4
Degos, L.5
Dejean, A.6
-
4
-
-
0025780876
-
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML
-
Kakizuka, A., Miller, W. H., Umesono, K., Warrell, R., Frankel, S., Dmitrovsky, E., and Evans, R. (1991) Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 66, 663-674
-
(1991)
Cell
, vol.66
, pp. 663-674
-
-
Kakizuka, A.1
Miller, W.H.2
Umesono, K.3
Warrell, R.4
Frankel, S.5
Dmitrovsky, E.6
Evans, R.7
-
5
-
-
0027104613
-
Combined therapy with all-trans retinoio acid and high-dose chemotherapy in patients with hyperleukocytic acute promyelocytic leukemia and severe visceral hemorrhage
-
Dombret, H., Sutton, L., Duarte, M., Daniel, M. T., Leblond, V., Castaigne, S., and Degos, L. (1992) Combined therapy with all-trans retinoio acid and high-dose chemotherapy in patients with hyperleukocytic acute promyelocytic leukemia and severe visceral hemorrhage. Leukemia 6, 1237-1242
-
(1992)
Leukemia
, vol.6
, pp. 1237-1242
-
-
Dombret, H.1
Sutton, L.2
Duarte, M.3
Daniel, M.T.4
Leblond, V.5
Castaigne, S.6
Degos, L.7
-
6
-
-
0023752982
-
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
-
Huang, M. E., Yu-Chen, Y., Shu-Rong, C., Lu, M. X., Zhoa, L., Gu, L. J., and Wang, Z. Y. (1988) Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72, 567-572
-
(1988)
Blood
, vol.72
, pp. 567-572
-
-
Huang, M.E.1
Yu-Chen, Y.2
Shu-Rong, C.3
Lu, M.X.4
Zhoa, L.5
Gu, L.J.6
Wang, Z.Y.7
-
7
-
-
0025241453
-
All trans retinoic acid in promyelocytic leukemias. II. in vitro studies structure function relationship
-
Chomienne, C., Ballerini, P., Balitrand, N., Daniel, M. T., Fenaux, P., Castaigne, S., and Degos, L. (1990) All trans retinoic acid in promyelocytic leukemias. II. In vitro studies structure function relationship. Blood 76, 1710-1717
-
(1990)
Blood
, vol.76
, pp. 1710-1717
-
-
Chomienne, C.1
Ballerini, P.2
Balitrand, N.3
Daniel, M.T.4
Fenaux, P.5
Castaigne, S.6
Degos, L.7
-
8
-
-
0025201879
-
All-trans retinoic acid as a differentiating therapy for acute promyelocytic leukemias. I. Clinical results
-
Castaigne, S., Chomienne, C., Daniel, M. T., Berger, R., Fenaux, P., and Degos, L. (1990) All-trans retinoic acid as a differentiating therapy for acute promyelocytic leukemias. I. Clinical results. Blood 76, 1704-1709
-
(1990)
Blood
, vol.76
, pp. 1704-1709
-
-
Castaigne, S.1
Chomienne, C.2
Daniel, M.T.3
Berger, R.4
Fenaux, P.5
Degos, L.6
-
9
-
-
0027957296
-
Review: Acute promyelocytic leukemia: from genetics to treatment
-
Grignani, F., Fagioli, M., Alcalay, M., Longo, L., Pandolfi, P., Donti, E., Biondi, A., Lo Coco, F., and Pellici, P. G. (1994) Review: acute promyelocytic leukemia: from genetics to treatment. Blood 83, 10-25
-
(1994)
Blood
, vol.83
, pp. 10-25
-
-
Grignani, F.1
Fagioli, M.2
Alcalay, M.3
Longo, L.4
Pandolfi, P.5
Donti, E.6
Biondi, A.7
Lo Coco, F.8
Pellici, P.G.9
-
10
-
-
0027173862
-
Acute promyelocytic leukemia
-
Warrell, R. P., Jr., de Thé, H., Wang, Z. Y., and Degos, L. (1993) Acute promyelocytic leukemia. N. Engl. J. Med. 329, 177-183
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 177-183
-
-
Warrell Jr., R.P.1
De Thé, H.2
Wang, Z.Y.3
Degos, L.4
-
11
-
-
0026652137
-
A PML/RARα fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia
-
Castaigne, S., Balitrand, N., de Thé, H., Dejean, A., Degos, L., and Chomienne, C. (1992) A PML/RARα fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia. Blood. 79, 3110-3115
-
(1992)
Blood.
, vol.79
, pp. 3110-3115
-
-
Castaigne, S.1
Balitrand, N.2
De Thé, H.3
Dejean, A.4
Degos, L.5
Chomienne, C.6
-
12
-
-
0027237223
-
Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for PML-RARα fusion mRNA
-
Miller, W. H., Levine, K., DeBlasio, A., Frankel, S. R., Dmitrovsky, E., and Warrell, R. P. (1993) Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for PML-RARα fusion mRNA. Blood 82, 1689-1694
-
(1993)
Blood
, vol.82
, pp. 1689-1694
-
-
Miller, W.H.1
Levine, K.2
DeBlasio, A.3
Frankel, S.R.4
Dmitrovsky, E.5
Warrell, R.P.6
-
13
-
-
0028575953
-
Monitoring of treatment outcome in acute promyelocytic leukemia by RT-PCR
-
Diverio, D., Pandolfi, P .P., Rossi, V., Biondi, A., Pelicci, P. G., and LoCoco, F. (1994) Monitoring of treatment outcome in acute promyelocytic leukemia by RT-PCR. Leukemia 8, 1105-1107
-
(1994)
Leukemia
, vol.8
, pp. 1105-1107
-
-
Diverio, D.1
Pandolfi, P.P.2
Rossi, V.3
Biondi, A.4
Pelicci, P.G.5
Lococo, F.6
-
14
-
-
0028899552
-
Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)
-
Licht J. D, Chomienne, C., Goy, A., Chen, A., Scott, A. A, Head, D. R., Michaux, J. L., Wu, Y., Deblasio, A., and Miller, W. H. (1995) Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17). Blood 85, 1083-1094
-
(1995)
Blood
, vol.85
, pp. 1083-1094
-
-
Licht, J.D.1
Chomienne, C.2
Goy, A.3
Chen, A.4
Scott, A.A.5
Head, D.R.6
Michaux, J.L.7
Wu, Y.8
Deblasio, A.9
Miller, W.H.10
-
15
-
-
0028040305
-
Poor response to all-trans retinoic acid therapy in a t(11;17) PLZF/RARα patient
-
Guidez, F., Huang, W., Tong, J. H., Dubois, C., Balitrand, N., Waxman, S., Michaux, J. L., Martiat, P., Degos, L., Chen, Z., and Chomienne, C. (1994) Poor response to all-trans retinoic acid therapy in a t(11;17) PLZF/RARα patient. Leukemia 8, 312-317
-
(1994)
Leukemia
, vol.8
, pp. 312-317
-
-
Guidez, F.1
Huang, W.2
Tong, J.H.3
Dubois, C.4
Balitrand, N.5
Waxman, S.6
Michaux, J.L.7
Martiat, P.8
Degos, L.9
Chen, Z.10
Chomienne, C.11
-
16
-
-
0030022316
-
The t(5;17) variant of acute promyelocytic leukemis expresses a nucleophosmin-retinoic acid receptor fusion
-
Redner, R. L., Rush, E. A., Faas, S., Rudert, W. A., and Corey, S. J. (1996) The t(5;17) variant of acute promyelocytic leukemis expresses a nucleophosmin-retinoic acid receptor fusion. Blood 87, 882-886
-
(1996)
Blood
, vol.87
, pp. 882-886
-
-
Redner, R.L.1
Rush, E.A.2
Faas, S.3
Rudert, W.A.4
Corey, S.J.5
-
17
-
-
0027219913
-
Retinoic acid supports granulocytic but not erythroid differentiation of myetoid progenitors in normal bone marrow cells
-
Gratas, C., Menot, M. L., Dresch, C., and Chomienne, C. (1993) Retinoic acid supports granulocytic but not erythroid differentiation of myetoid progenitors in normal bone marrow cells. Leukemia 7, 1156-1162
-
(1993)
Leukemia
, vol.7
, pp. 1156-1162
-
-
Gratas, C.1
Menot, M.L.2
Dresch, C.3
Chomienne, C.4
-
18
-
-
0027502549
-
Direct effects of 13-cis and all-trans retinoic acid on normal bone marrow (BM) progenitors: Comparative study on BM mononuclear cells and on isolated CD34+ BM cells
-
Van Bockstaele, D. R., Lenjou, M., Snoeck, H. W., Lardon, F., Stryckmans, P., and Peetermans, M. E. (1993) Direct effects of 13-cis and all-trans retinoic acid on normal bone marrow (BM) progenitors: comparative study on BM mononuclear cells and on isolated CD34+ BM cells. Ann. Haematol. 66, 61-66
-
(1993)
Ann. Haematol.
, vol.66
, pp. 61-66
-
-
Van Bockstaele, D.R.1
Lenjou, M.2
Snoeck, H.W.3
Lardon, F.4
Stryckmans, P.5
Peetermans, M.E.6
-
19
-
-
0025271098
-
Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RARα)
-
Collins S. J., Roberton K. A., and Mueller, L. (1990) Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RARα). Mol. Cell. Biol. 10, 2154-2163
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 2154-2163
-
-
Collins, S.J.1
Roberton, K.A.2
Mueller, L.3
-
20
-
-
0028176437
-
The PML-RARα gene product of the t(15:17) translocation inhibits retinoic acid induced granulocytic differentiation
-
Rousselot, P., Hardas, B., Castaigne, S., Dejean, A., de Thé, H., Degos, L., Farzaneh, F., and Chomienne, C. (1994) The PML-RARα gene product of the t(15:17) translocation inhibits retinoic acid induced granulocytic differentiation. Oncogene 9, 545-551
-
(1994)
Oncogene
, vol.9
, pp. 545-551
-
-
Rousselot, P.1
Hardas, B.2
Castaigne, S.3
Dejean, A.4
De Thé, H.5
Degos, L.6
Farzaneh, F.7
Chomienne, C.8
-
21
-
-
0028179425
-
PLZF-RAR fusion protein generated from the translocation t(11;17)(q23;q21) displays altered transactivation properties against the wild-type retinoic acid receptors
-
Chen, Z., Guidez, F., Rousselot, P., Agadir, A., Chen, S. J., Wang, Z. Y., Degos, L., Waxman, S., Zelent, A., and Chomienne, C. (1994) PLZF-RAR fusion protein generated from the translocation t(11;17)(q23;q21) displays altered transactivation properties against the wild-type retinoic acid receptors. Proc. Natl. Acad. Sci. USA 91, 1178-1182
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1178-1182
-
-
Chen, Z.1
Guidez, F.2
Rousselot, P.3
Agadir, A.4
Chen, S.J.5
Wang, Z.Y.6
Degos, L.7
Waxman, S.8
Zelent, A.9
Chomienne, C.10
-
22
-
-
0028293945
-
The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion
-
Koken, M. H. M., Puvion-Dutilleuil, F., Guillemin, M. C., Viron, A., Linares-Cruz, G., Stuurman, N., de Jong, L., Szostecki, C., Calvo, F., Chomienne, C., Degos, L., Puvion, E., and de Thé, H. (1994) The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion. EMBO J. 13, 1073-1083
-
(1994)
EMBO J.
, vol.13
, pp. 1073-1083
-
-
Koken, M.H.M.1
Puvion-Dutilleuil, F.2
Guillemin, M.C.3
Viron, A.4
Linares-Cruz, G.5
Stuurman, N.6
De Jong, L.7
Szostecki, C.8
Calvo, F.9
Chomienne, C.10
Degos, L.11
Puvion, E.12
De Thé, H.13
-
23
-
-
0027320110
-
The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells
-
Crignani, F., Ferrucci, P. F., Testa, U., Talamo, G., Fagioli, M., Alcalay, M., Mencarelli, A., Crignani, F., Peschle, C., Nicoletti, L., and Pellici P. G. (1993) The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. Cell 74, 423-431
-
(1993)
Cell
, vol.74
, pp. 423-431
-
-
Crignani, F.1
Ferrucci, P.F.2
Testa, U.3
Talamo, G.4
Fagioli, M.5
Alcalay, M.6
Mencarelli, A.7
Crignani, F.8
Peschle, C.9
Nicoletti, L.10
Pellici, P.G.11
-
24
-
-
0028894265
-
Promyelocytic leukemia-specific PML-retinoic acid alpha receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells
-
Grignani, F., Testa, U., Mascuilli, R., Mariani, G., Fagioli, M., Barberi, T., Peschle, C., and Pelicci, P. G. (1995) Promyelocytic leukemia-specific PML-retinoic acid alpha receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells. Cancer Res. 55, 440-443
-
(1995)
Cancer Res.
, vol.55
, pp. 440-443
-
-
Grignani, F.1
Testa, U.2
Mascuilli, R.3
Mariani, G.4
Fagioli, M.5
Barberi, T.6
Peschle, C.7
Pelicci, P.G.8
-
25
-
-
0028942312
-
Highly purified primitive hematopoietic stem cells are PML-RARα negative and generate monoclonal progenitors in acute promyelocytic leukemia
-
Turhan, A. G., Lemoine, F. M., Debert, C., Bonnet, M. L., Baillou, C., Picard, F., Macintyre, E. A., and Varet, B. (1995) Highly purified primitive hematopoietic stem cells are PML-RARα negative and generate monoclonal progenitors in acute promyelocytic leukemia. Blood 85, 2154-2161
-
(1995)
Blood
, vol.85
, pp. 2154-2161
-
-
Turhan, A.G.1
Lemoine, F.M.2
Debert, C.3
Bonnet, M.L.4
Baillou, C.5
Picard, F.6
Macintyre, E.A.7
Varet, B.8
-
26
-
-
0030051723
-
All-trans retinoic acid rapidly decreases cathepsin G synthesis and mRNA expression in acute promyelocytic leukemia
-
Seale, J, Delva L., Renesto P., Balitrand, N., Dombret, H., Scrobohaci, M. L., Degos. L., Paul, P., and Chomienne, C. (1996) All-trans retinoic acid rapidly decreases cathepsin G synthesis and mRNA expression in acute promyelocytic leukemia. Leukemia 10, 95-101
-
(1996)
Leukemia
, vol.10
, pp. 95-101
-
-
Seale, J.1
Delva, L.2
Renesto, P.3
Balitrand, N.4
Dombret, H.5
Scrobohaci, M.L.6
Degos, L.7
Paul, P.8
Chomienne, C.9
-
27
-
-
0028061922
-
Induction of high-affinity CM-CSF receptor during all- Trans retinoic acid treatment of acute promyelocylic leukemia
-
De Gentile, A., Toubert, M. E., Dubois, C., Krawice, I., Schlageter, M. H., Balitrand, N., Castaigne, S., Degos, L., Rain, J. D., Najean, Y., and Chomienne, C. (1994) Induction of high-affinity CM-CSF receptor during all- trans retinoic acid treatment of acute promyelocylic leukemia Leukemia 8, 1758-1762
-
(1994)
Leukemia
, vol.8
, pp. 1758-1762
-
-
De Gentile, A.1
Toubert, M.E.2
Dubois, C.3
Krawice, I.4
Schlageter, M.H.5
Balitrand, N.6
Castaigne, S.7
Degos, L.8
Rain, J.D.9
Najean, Y.10
Chomienne, C.11
-
28
-
-
0028171394
-
Modulation of 11-6 and 11-1β and G-CSF secretion by all-trans retinoic acid in acute promyelocylic leukemia
-
Dubois, C., Schlageter, M. H., De Gentile, A., Guidez, F., Balitrand, N., Toubert, M. E., Krawice, I., Fenaux, P., Castaigne, S., Najean, Y., Degos, L., and Chomienne, C. (1994) Modulation of 11-6 and 11-1β and G-CSF secretion by all-trans retinoic acid in acute promyelocylic leukemia Leukemia 8, 1750-1757
-
(1994)
Leukemia
, vol.8
, pp. 1750-1757
-
-
Dubois, C.1
Schlageter, M.H.2
De Gentile, A.3
Guidez, F.4
Balitrand, N.5
Toubert, M.E.6
Krawice, I.7
Fenaux, P.8
Castaigne, S.9
Najean, Y.10
Degos, L.11
Chomienne, C.12
-
29
-
-
0025139398
-
HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis
-
Martin, S. J., Bradley, J. G., and Cotter, T. G. (1990) HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis. Clin. Exp. Immunol. 79, 448-453
-
(1990)
Clin. Exp. Immunol.
, vol.79
, pp. 448-453
-
-
Martin, S.J.1
Bradley, J.G.2
Cotter, T.G.3
-
30
-
-
0028168185
-
All-trans retinoic acid and induction of apoptosis in acute promyelocylic leukemia cells
-
Tosi, P., Visani, G., Gibellini, D., Zauli, G., Ottoviani, E., Cenacchi, A., Gamberi, B., Manfrois, S., Marchisio M., and Turas, S. (1994) All-trans retinoic acid and induction of apoptosis in acute promyelocylic leukemia cells. Leukemia & Lymphoma 14, 503-507
-
(1994)
Leukemia & Lymphoma
, vol.14
, pp. 503-507
-
-
Tosi, P.1
Visani, G.2
Gibellini, D.3
Zauli, G.4
Ottoviani, E.5
Cenacchi, A.6
Gamberi, B.7
Manfrois, S.8
Marchisio, M.9
Turas, S.10
-
31
-
-
0029557419
-
In vitro treatment with retinoids or the lopoisomerase inhibitor, VP16, evidences different functional apoptotic pathways in acute promyelocytic leukemic cells
-
Calabresse, C., Barbey, S., Venturini, L., Balitrand, N., Degos, L., Fenaux, P., and Chomienne, C. (1995) In vitro treatment with retinoids or the lopoisomerase inhibitor, VP16, evidences different functional apoptotic pathways in acute promyelocytic leukemic cells. Leukemia 9, 2049-2057
-
(1995)
Leukemia
, vol.9
, pp. 2049-2057
-
-
Calabresse, C.1
Barbey, S.2
Venturini, L.3
Balitrand, N.4
Degos, L.5
Fenaux, P.6
Chomienne, C.7
-
32
-
-
0028339174
-
Hematopoietic growth factor expression and ATRA sensitivity in acute promyelocytic leukemia
-
Dubois, C., Schlageter, M. H., De Gentile, A., Guidez, F., Balitrand, N., Toubert, M. E., Krawice, I., Fenaux, P., Castaigne, S., Najean, Y., Degos, L., and Chomienne, C. (1991) Hematopoietic growth factor expression and ATRA sensitivity in acute promyelocytic leukemia. Blood 83, 3264-3270
-
(1991)
Blood
, vol.83
, pp. 3264-3270
-
-
Dubois, C.1
Schlageter, M.H.2
De Gentile, A.3
Guidez, F.4
Balitrand, N.5
Toubert, M.E.6
Krawice, I.7
Fenaux, P.8
Castaigne, S.9
Najean, Y.10
Degos, L.11
Chomienne, C.12
-
33
-
-
0029794132
-
A decade of molecular biology of retinoic acid receptors
-
Chambon, P. (1996) A decade of molecular biology of retinoic acid receptors. FASEB J. 10, 940-954
-
(1996)
FASEB J.
, vol.10
, pp. 940-954
-
-
Chambon, P.1
-
34
-
-
0029121672
-
Characterization of nuclear retinoic acid binding activity in sensitive leukemic cell lines: Cell specific uptake of ATRA and RARα protein modulation
-
Agadir, A., Cornic, M., Jerome, M., Menot, M. L., Cambier, N., Gaub, M. P., Gourmel, B., Lefebvre, P., Degos L., and Chomienne, C. (1995) Characterization of nuclear retinoic acid binding activity in sensitive leukemic cell lines: cell specific uptake of ATRA and RARα protein modulation. BBRC 213, 112-122
-
(1995)
BBRC
, vol.213
, pp. 112-122
-
-
Agadir, A.1
Cornic, M.2
Jerome, M.3
Menot, M.L.4
Cambier, N.5
Gaub, M.P.6
Gourmel, B.7
Lefebvre, P.8
Degos, L.9
Chomienne, C.10
-
35
-
-
0026316082
-
All-trans retinoic acid modulates the retinoic acid receptor alpha in promyelocylic cells
-
Chomienne, C., Balitrand, N., Ballerini, P., Castaigne, S., de Thé, H., and Degos, L. (1991) All-trans retinoic acid modulates the retinoic acid receptor alpha in promyelocylic cells. J. Clin. Invest. 88, 2150-2154
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 2150-2154
-
-
Chomienne, C.1
Balitrand, N.2
Ballerini, P.3
Castaigne, S.4
De Thé, H.5
Degos, L.6
-
36
-
-
0026583943
-
Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins
-
Kastner, P., Perez, A., Lutz, Y., Rochette-Egly, C., Gaub, M. P., Durand, B., Lanotte, M., Berger, R., and Chambon, P. (1992) Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins. EMBO J. 11, 629-642
-
(1992)
EMBO J.
, vol.11
, pp. 629-642
-
-
Kastner, P.1
Perez, A.2
Lutz, Y.3
Rochette-Egly, C.4
Gaub, M.P.5
Durand, B.6
Lanotte, M.7
Berger, R.8
Chambon, P.9
-
37
-
-
0026316097
-
Pharmacokinetics of all-trans RA in patients with acute promyelocylic
-
Lefebvre, P., Thomas, G., Gourmel, B., Dreux, C., Castaigne, S., and Chomienne, C. (1991) Pharmacokinetics of all-trans RA in patients with acute promyelocylic. Leukemia 5, 1054-1058
-
(1991)
Leukemia
, vol.5
, pp. 1054-1058
-
-
Lefebvre, P.1
Thomas, G.2
Gourmel, B.3
Dreux, C.4
Castaigne, S.5
Chomienne, C.6
-
38
-
-
0026536835
-
Continuous treatment with all-trans RA progressively decreases plasma drug concentrations: Implications for relapse and resistance in acute promyelocytic leukemia
-
Muindi, J., Frazkel, S. R., Miller, W. H., Jakubowski, A., Scheinberg, D. A., Young, C. W., and Dimitrovsky, E. (1992) Continuous treatment with all-trans RA progressively decreases plasma drug concentrations: implications for relapse and resistance in acute promyelocytic leukemia. Blood 79, 299-303
-
(1992)
Blood
, vol.79
, pp. 299-303
-
-
Muindi, J.1
Frazkel, S.R.2
Miller, W.H.3
Jakubowski, A.4
Scheinberg, D.A.5
Young, C.W.6
Dimitrovsky, E.7
-
39
-
-
0028922809
-
Differential uptake of all-trans retinoic acid by acute promyelocytic leukemic cells: Evidence for its role in retinoic acid efficacity
-
Agadir, A., Cornic, C., Lefebvre, P., Gourmel, B., Balitrand, N., Degos, L., and Chomienne, C. (1995) Differential uptake of all-trans retinoic acid by acute promyelocytic leukemic cells: Evidence for its role in retinoic acid efficacity. Leukemia 9, 139-145
-
(1995)
Leukemia
, vol.9
, pp. 139-145
-
-
Agadir, A.1
Cornic, C.2
Lefebvre, P.3
Gourmel, B.4
Balitrand, N.5
Degos, L.6
Chomienne, C.7
-
40
-
-
0029151010
-
All-trans retinoic acid pharmacokinetics and bioavailability in acute promyelocytic leukemia: Intracellular concentrations and biologic response relationship
-
Agadir, A., Cornic, M., Lefebvre, P., Gourmel, B., Jerome, M., Degos, L., Fenaux, P., and Chomienne, C. (1995) All-trans retinoic acid pharmacokinetics and bioavailability in acute promyelocytic leukemia: Intracellular concentrations and biologic response relationship. J. Clin. Oncol. 13, 2517-2523
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 2517-2523
-
-
Agadir, A.1
Cornic, M.2
Lefebvre, P.3
Gourmel, B.4
Jerome, M.5
Degos, L.6
Fenaux, P.7
Chomienne, C.8
-
41
-
-
0029839230
-
Retinoic acid biosynthesis and metabolism
-
Napoli, J. L. (1996) Retinoic acid biosynthesis and metabolism. FASEB J. 10, 993-1001
-
(1996)
FASEB J.
, vol.10
, pp. 993-1001
-
-
Napoli, J.L.1
-
42
-
-
0027517243
-
Resistance to all-trans retinoic acid therapy in relapsing acute promyelocytic leukemia
-
Delva, L., Cornic, M., Balitrand, N., Guidez, F., Miclea, J. M., Delmer, A., Teillet, F., Fenaux, P., Castaigne, S., Degos, L., and Chomienne, C. (1993) Resistance to all-trans retinoic acid therapy in relapsing acute promyelocytic leukemia. Blood 82, 2175-2181
-
(1993)
Blood
, vol.82
, pp. 2175-2181
-
-
Delva, L.1
Cornic, M.2
Balitrand, N.3
Guidez, F.4
Miclea, J.M.5
Delmer, A.6
Teillet, F.7
Fenaux, P.8
Castaigne, S.9
Degos, L.10
Chomienne, C.11
-
43
-
-
0028056048
-
In vitro all-trans retinoic acid (ATRA) sensitivity and cellular retinoic acid binding protein (CRABP) levels in relapse leukemic cells after remisssion induction by ATRA in acute promyelocytic leukemia
-
Cornic, M., Delva, L., Castaigne, S., Balitrand, N., Degos, L., and Chomienne, C. (1994) In vitro all-trans retinoic acid (ATRA) sensitivity and cellular retinoic acid binding protein (CRABP) levels in relapse leukemic cells after remisssion induction by ATRA in acute promyelocytic leukemia. Leukemia 8, 914-917
-
(1994)
Leukemia
, vol.8
, pp. 914-917
-
-
Cornic, M.1
Delva, L.2
Castaigne, S.3
Balitrand, N.4
Degos, L.5
Chomienne, C.6
-
44
-
-
0025882306
-
Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans retinoic acid)
-
Warrell, R. P., Frankel, S. R., Miller, W., Itri, L., Andreeff, M., Jabukowski, A., Gabrilove, J., Gordon, M. S., and Dmitrovsky, E. (1991) Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans retinoic acid). N. Engl. J. Med. 324, 1385-1393
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 1385-1393
-
-
Warrell, R.P.1
Frankel, S.R.2
Miller, W.3
Itri, L.4
Andreeff, M.5
Jabukowski, A.6
Gabrilove, J.7
Gordon, M.S.8
Dmitrovsky, E.9
-
45
-
-
0028198870
-
Treatment of acute promyelocytic leukemia with all-trans retinoic acid: An update of the New York experience
-
Warrell, R. P., Maslak, P., Eardley, A., Heller, G., Miller, W. H., and Frankel, S. R. (1994) Treatment of acute promyelocytic leukemia with all-trans retinoic acid: an update of the New York experience. Leukemia 8, 926-933
-
(1994)
Leukemia
, vol.8
, pp. 926-933
-
-
Warrell, R.P.1
Maslak, P.2
Eardley, A.3
Heller, G.4
Miller, W.H.5
Frankel, S.R.6
-
46
-
-
0028960267
-
All-trans retinoic acid for the treatment of newly diagnosed acute promyelocytic leukemia
-
Kanamaru, A., Takemoto, Y., Tanimoto, M., Murakami, H., Asou, N., Kobayashi, T., Kuriyama, K., Ohmoto E., Sakamaki, H., Tsubaki, K., Hiraoka, A., Yamada, O., Oh, H., Saito, K., Matsuda, S., Minato, K., Ueda, T., and Ohno, R. (1995) all-trans retinoic acid for the treatment of newly diagnosed acute promyelocytic leukemia. Blood 85, 1202-1206
-
(1995)
Blood
, vol.85
, pp. 1202-1206
-
-
Kanamaru, A.1
Takemoto, Y.2
Tanimoto, M.3
Murakami, H.4
Asou, N.5
Kobayashi, T.6
Kuriyama, K.7
Ohmoto, E.8
Sakamaki, H.9
Tsubaki, K.10
Hiraoka, A.11
Yamada, O.12
Oh, H.13
Saito, K.14
Matsuda, S.15
Minato, K.16
Ueda, T.17
Ohno, R.18
-
47
-
-
0029069494
-
Reduction of pulmonary toxicity by prednisolone prophylaxis during all-trans retinoic acid treatment of acute promyelocylic leukemia
-
Wiley, J. S., and Firkin, F. C. (1995) Reduction of pulmonary toxicity by prednisolone prophylaxis during all-trans retinoic acid treatment of acute promyelocylic leukemia. Leukemia 9, 774-778
-
(1995)
Leukemia
, vol.9
, pp. 774-778
-
-
Wiley, J.S.1
Firkin, F.C.2
-
48
-
-
0026788363
-
All-trans retinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia: A pilot study on 26 cases
-
Fenaux, P., Castaigne, S., Dombret, H., Archimbaud, E., Duarte, M., Morel, P., Lamy, T., Tilly, H., Guerci, A., Maloisel, F., Bordessoule, D., Sadoun, A., Tiberghien, P., Fegueux, N., Daniel, M. T., Chomienne, C., and Degos, L. (1992) All-trans retinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia: a pilot study on 26 cases. Blood 80, 2176-2181
-
(1992)
Blood
, vol.80
, pp. 2176-2181
-
-
Fenaux, P.1
Castaigne, S.2
Dombret, H.3
Archimbaud, E.4
Duarte, M.5
Morel, P.6
Lamy, T.7
Tilly, H.8
Guerci, A.9
Maloisel, F.10
Bordessoule, D.11
Sadoun, A.12
Tiberghien, P.13
Fegueux, N.14
Daniel, M.T.15
Chomienne, C.16
Degos, L.17
-
49
-
-
0028228247
-
Prolonged follow up confirms that all-trans retinoic acid (ATRA) followed by chemotherapy reduces the risk of relapse in newly diagnosed acute promyelocytic leukemia (APL)
-
Fenaux, P., Wattel, E., Archimbaud, E., Sanz, M., Hecquet, B., Guerci, A., Link,. H, Fegueux, N., Fey, M., Castaigne, S., and Degos, L. (1994) Prolonged follow up confirms that all-trans retinoic acid (ATRA) followed by chemotherapy reduces the risk of relapse in newly diagnosed acute promyelocytic leukemia (APL). Blood 84, 666-667
-
(1994)
Blood
, vol.84
, pp. 666-667
-
-
Fenaux, P.1
Wattel, E.2
Archimbaud, E.3
Sanz, M.4
Hecquet, B.5
Guerci, A.6
Link, H.7
Fegueux, N.8
Fey, M.9
Castaigne, S.10
Degos, L.11
-
50
-
-
0027368561
-
Effect of all trans retinoic acid in newly diagnosed acute promyelocytic leukemia. Results of a multicenter randomized trial
-
Fenaux, P., Le Deley, M. C., Castaigne, S., Archimbaud, E., Chomienne, C., Link, H., Guerci, A., Duarte, M., Daniel, M. T., Bowen, D., Huebner, G., Bauters, F., Fegueux, N., Fey, M., Sanz, M., Lowenberg, B., Maloisel, F., Auzanneau, G., Sadoun, A., Gardin, C., Bastion, Y., Ganser, A., Jacky, E., Dombret, H., Chastang, C., and Degos, L. (1993) Effect of all trans retinoic acid in newly diagnosed acute promyelocytic leukemia. Results of a multicenter randomized trial. Blood 82, 3241-3249
-
(1993)
Blood
, vol.82
, pp. 3241-3249
-
-
Fenaux, P.1
Le Deley, M.C.2
Castaigne, S.3
Archimbaud, E.4
Chomienne, C.5
Link, H.6
Guerci, A.7
Duarte, M.8
Daniel, M.T.9
Bowen, D.10
Huebner, G.11
Bauters, F.12
Fegueux, N.13
Fey, M.14
Sanz, M.15
Lowenberg, B.16
Maloisel, F.17
Auzanneau, G.18
Sadoun, A.19
Gardin, C.20
Bastion, Y.21
Ganser, A.22
Jacky, E.23
Dombret, H.24
Chastang, C.25
Degos, L.26
more..
-
51
-
-
0028205216
-
Tretinoin with chemotherapy in newly diagnosed acute promyelocytic leukaemia
-
Fenaux, P., Chastang, C., Chomienne, C., and Degos, L. (1994) Tretinoin with chemotherapy in newly diagnosed acute promyelocytic leukaemia. Lancet 343, 1033
-
(1994)
Lancet
, vol.343
, pp. 1033
-
-
Fenaux, P.1
Chastang, C.2
Chomienne, C.3
Degos, L.4
-
52
-
-
0028999532
-
All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocylic leukemia
-
Degos, L., Dombret, H., Chomienne, C., Daniel, M. T., Miclea, J. M., Chastang, C., Castaigne, S., and Fenaux, P. (1995) All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocylic leukemia. Blood 85, 2643-2653
-
(1995)
Blood
, vol.85
, pp. 2643-2653
-
-
Degos, L.1
Dombret, H.2
Chomienne, C.3
Daniel, M.T.4
Miclea, J.M.5
Chastang, C.6
Castaigne, S.7
Fenaux, P.8
-
53
-
-
0025223760
-
Treatment of first relapse in acute promyelocytic leukaemia with all trans retinoic acid
-
Degos, L., Chomienne, C., Daniel, M. T., Berger, R., Dombret, H., Fenaux, P., and Castaigne, S. (1990) Treatment of first relapse in acute promyelocytic leukaemia with all trans retinoic acid. Lancet 2, 1440-1441
-
(1990)
Lancet
, vol.2
, pp. 1440-1441
-
-
Degos, L.1
Chomienne, C.2
Daniel, M.T.3
Berger, R.4
Dombret, H.5
Fenaux, P.6
Castaigne, S.7
-
54
-
-
0011894435
-
Phase III randomized study of all-trans retoinoic acid Vs Daunorubicin and Ara-C as induction therapy, 10 patients with previously untreated APL
-
Tallman, M. S., Andersen, J., Schiffer, C. A., Appelbaum, F, R., Feusner, J. E., Woods, W. G., Ogder, A., Weinstein, H., Sheperd, L., Rowe, J. M., and Wierznik, P. M. (1995) Phase III randomized study of all-trans retoinoic acid Vs Daunorubicin and Ara-C as induction therapy, 10 patients with previously untreated APL. Blood 86 (Suppl.), 125a
-
(1995)
Blood
, vol.86
, Issue.SUPPL.
-
-
Tallman, M.S.1
Andersen, J.2
Schiffer, C.A.3
Appelbaum, F.R.4
Feusner, J.E.5
Woods, W.G.6
Ogder, A.7
Weinstein, H.8
Sheperd, L.9
Rowe, J.M.10
Wierznik, P.M.11
-
55
-
-
0028336778
-
Morbidity and costs of remission induction therapy with all-trans retinoic acid compared with standard chemotherapy in acute promyelocyitic leukemia
-
Eardley, A. M., Heller, G., and Warrell, R. P. (1994) Morbidity and costs of remission induction therapy with all-trans retinoic acid compared with standard chemotherapy in acute promyelocyitic leukemia. Leukemia 8, 934-939.
-
(1994)
Leukemia
, vol.8
, pp. 934-939
-
-
Eardley, A.M.1
Heller, G.2
Warrell, R.P.3
-
56
-
-
0026647140
-
The "retinoic acid syndrome" in acute promyelocytic leukemia
-
Frankel, S. R., Eardley, A., Lauwers, G., Weiss, M., and Warrell, R. (1992) The "retinoic acid syndrome" in acute promyelocytic leukemia. Ann. Int. Med. 117, 292-296
-
(1992)
Ann. Int. Med.
, vol.117
, pp. 292-296
-
-
Frankel, S.R.1
Eardley, A.2
Lauwers, G.3
Weiss, M.4
Warrell, R.5
-
57
-
-
0027484628
-
Multi-institutional study of all-trans retinoic acid as a differentiation therapy of refractory acute promyelocytic leukemia
-
Ohno, R., Yoshida, H., and Fukutani, H. (1993) Multi-institutional study of all-trans retinoic acid as a differentiation therapy of refractory acute promyelocytic leukemia. Leukemia 7, 1722-1727
-
(1993)
Leukemia
, vol.7
, pp. 1722-1727
-
-
Ohno, R.1
Yoshida, H.2
Fukutani, H.3
-
58
-
-
0027417853
-
Coagulation disorders associated with acute promyelocytic leukemia: Corrective effect of all-trans retinoic acid treatment
-
Dombret, H., Scrobohaci, M. L., Ghorra, P., Zini, J. M., Daniel, M. T., Castaigne, S., and Degos, L. (1993) Coagulation disorders associated with acute promyelocytic leukemia: Corrective effect of all-trans retinoic acid treatment. Leukemia 7, 2-9
-
(1993)
Leukemia
, vol.7
, pp. 2-9
-
-
Dombret, H.1
Scrobohaci, M.L.2
Ghorra, P.3
Zini, J.M.4
Daniel, M.T.5
Castaigne, S.6
Degos, L.7
-
59
-
-
0026766042
-
Retinoic acid in the treatment of acute promyelocytic leukemia: Inefficacy of the 13-cis isomer and induction of complete remission by the all-trans isomer complicated by thromboembolic events
-
Runde, V., Aul, C., Sudhoff, T., Heyll, A., and Schneider, W. (1993) Retinoic acid in the treatment of acute promyelocytic leukemia: Inefficacy of the 13-cis isomer and induction of complete remission by the all-trans isomer complicated by thromboembolic events. Ann. Hematol. 64, 270-272
-
(1993)
Ann. Hematol.
, vol.64
, pp. 270-272
-
-
Runde, V.1
Aul, C.2
Sudhoff, T.3
Heyll, A.4
Schneider, W.5
-
60
-
-
0027194394
-
Acute promyelocytic leukemia: Clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse
-
Huang, W., Sun, G. L., Li, X. S., Cao, Q., Lu, Y., Jang, G. S., Zhang, F Q., Chai, J. R., Wang, Z. Y., and Waxman, S. (1993) Acute promyelocytic leukemia: clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse. Blood 82, 1264-1269
-
(1993)
Blood
, vol.82
, pp. 1264-1269
-
-
Huang, W.1
Sun, G.L.2
Li, X.S.3
Cao, Q.4
Lu, Y.5
Jang, G.S.6
Zhang, F.Q.7
Chai, J.R.8
Wang, Z.Y.9
Waxman, S.10
-
61
-
-
0027937940
-
Early mortality and the retinoic acid syndrome in acute promyelocytic leukemia. Impact of leucocytosis, low dose chemotherapy, PML-RARα isoform and CDB expression in patients treated with all-trans retinoic acid
-
Vadhat, L., Maslak, P., Miller, W. H., Eardley, A., Heller, G., Scheinberg, D. A., and Warrell, R. P. (1994) Early mortality and the retinoic acid syndrome in acute promyelocytic leukemia. Impact of leucocytosis, low dose chemotherapy, PML-RARα isoform and CDB expression in patients treated with all-trans retinoic acid. Blood 84, 3843-3849
-
(1994)
Blood
, vol.84
, pp. 3843-3849
-
-
Vadhat, L.1
Maslak, P.2
Miller, W.H.3
Eardley, A.4
Heller, G.5
Scheinberg, D.A.6
Warrell, R.P.7
-
62
-
-
0028908197
-
Prognostic significance of the RT-PCR assay of PML-RARα transcripts in acute promyelocytic leukemia. the Leukemia Study Group of the Ministry of Health and Welfare (Kouseisho)
-
Fukutani, H., Naoe, T., Ohno, R., Yoshida, H., Kiyooi, H., Miyawaki, S., Morishita, H., Sano, F., Kmibayashi, H., and Matsue, K. (1995) Prognostic significance of the RT-PCR assay of PML-RARα transcripts in acute promyelocytic leukemia. The Leukemia Study Group of the Ministry of Health and Welfare (Kouseisho). Leukemia 9, 588-593
-
(1995)
Leukemia
, vol.9
, pp. 588-593
-
-
Fukutani, H.1
Naoe, T.2
Ohno, R.3
Yoshida, H.4
Kiyooi, H.5
Miyawaki, S.6
Morishita, H.7
Sano, F.8
Kmibayashi, H.9
Matsue, K.10
-
63
-
-
0030009694
-
RT-PCR in acute promyelocylic leukemia. Second Workshop of the European Retinoic Group, Paris, France, December 17-18, 1994
-
Chomienne, C. (1995) RT-PCR in acute promyelocylic leukemia. Second Workshop of the European Retinoic Group, Paris, France, December 17-18, 1994. Leukemia 10, 368-371
-
(1995)
Leukemia
, vol.10
, pp. 368-371
-
-
Chomienne, C.1
-
64
-
-
0027405942
-
Time course of induction of metabolism of all trans retinoic acid and the up regulation of cellular retinoic acid binding protein
-
Adamson, P. C., Boylan, J. F., Balis, F. M., Murphy, R. F., Godwin, K. A., Cudas, L. J., and Poplack, D. G. (1993) Time course of induction of metabolism of all trans retinoic acid and the up regulation of cellular retinoic acid binding protein. Cancer Res 53, 472-476
-
(1993)
Cancer Res
, vol.53
, pp. 472-476
-
-
Adamson, P.C.1
Boylan, J.F.2
Balis, F.M.3
Murphy, R.F.4
Godwin, K.A.5
Cudas, L.J.6
Poplack, D.G.7
-
65
-
-
0027524546
-
Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid and its modulation by ketoconazole
-
Rigas, J. R., Francis, P. A., Muindi, J. R. F., Kris, M. G., Huselton, C., DeGrazia, F., Orazem, J. P., Young, C. W., and Warrell, R. P. (1993) Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid and its modulation by ketoconazole. J. Natl. Cancer Inst. 85, 1921-1926
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 1921-1926
-
-
Rigas, J.R.1
Francis, P.A.2
Muindi, J.R.F.3
Kris, M.G.4
Huselton, C.5
DeGrazia, F.6
Orazem, J.P.7
Young, C.W.8
Warrell, R.P.9
-
66
-
-
0029050432
-
9-cis Retinoic acid induces complete remission, but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia
-
Miller, W. H., Jakubowski A., Tong, W. A., Miller, V. A., Rigas, J. R., Bendetti, F., Gill, G. M., Truglia, J. A., Ulm, E., Shirley, M., and Warrell, R. P. (1995). 9-cis Retinoic acid induces complete remission, but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia. Blood 85, 3021-3027
-
(1995)
Blood
, vol.85
, pp. 3021-3027
-
-
Miller, W.H.1
Jakubowski, A.2
Tong, W.A.3
Miller, V.A.4
Rigas, J.R.5
Bendetti, F.6
Gill, G.M.7
Truglia, J.A.8
Ulm, E.9
Shirley, M.10
Warrell, R.P.11
-
67
-
-
0029906356
-
Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinnid, Am80
-
Tukeshita, A., Shibata, Y., Shinjo, K., Yanagi, M., Tobita, T., Ohnishi, K., Miyawaki, S., Shudo, K., and Ohno, R (1996) Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinnid, Am80. Ann. Int. Med. 124, 893-896
-
(1996)
Ann. Int. Med.
, vol.124
, pp. 893-896
-
-
Tukeshita, A.1
Shibata, Y.2
Shinjo, K.3
Yanagi, M.4
Tobita, T.5
Ohnishi, K.6
Miyawaki, S.7
Shudo, K.8
Ohno, R.9
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