Growth hormone response to growth hormone-releasing hormone varies with the hypothalamic-pituitary abnormalities

European Journal of Endocrinology

Volumn 135, Issue 2, 1996, Pages 198-204

  Maghnie, Mohamad ^a   Moretta, Antonia ^a   Valtorta, Anice ^a   Larizza, Daniela ^a   Sayegh, Mariam ^a   Greco, Anna Maria ^a   Castoldi, Enio ^a   Severi, Francesca ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR[1-29]; GROWTH HORMONE RELEASING FACTOR[1-40]; LEVODOPA; PROTIRELIN; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GROWTH HORMONE DEFICIENCY; HUMAN; HYPOPITUITARISM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INTRAVENOUS DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL;

EID: 0029838607     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1350198     Document Type: Article

References (34)

1. Vance ML, Kaiser DL, Evans WS, Thorner MO, Furlanetto R, Rivier J, et al. Evidence for a limited growth hormone (GH)-releasing hormone (GHRH)-releasable quantity of GH: effects of 6-hour infusions of GHRH on GH secretions in normal man. J Clin Endocrinol Metab 1985;60:370-5
2. Vance ML, Kaiser DL, Evans WS, Furlanetto R, Vale W, Rivier J, et al. Pulsatile growth hormone secretion in normal man during a continuous 24-hour infusion of human growth hormone releasing factor (1-40). Evidence for intermittent somatostatin secretion. J Clin Invest 1985;75:1584-90
3. Vance ML, Kaiser DL, Rivier J, Vale W, Throner MO. Dual effects of growth hormone (GH)-releasing hormone infusion in normal men: somatotroph desensitization and increase in releasable GH. J Clin Endocrinol Metab 1986;62:591-4
4. Davis JRB, Sheppard MC, Shakespear RA, Lynch SS, Clayton RN. Does growth hormone releasing factor desensitize the somatotroph? interpretation of responses of growth hormone during and after 10-hour infusion of GRF 1-29 amide in man. Clin Endocrinol (Oxf) 1986;24:135-40
5. Brain C, Hindmarsh PC, Brook CGD, Matthews DR. Continuous subcutaneous growth hormone releasing factor augments growth hormone secretion in normal male subjects with no desensitization of the somatotroph. Clin Endocrinol (Oxf) 1988;28:543-9
6. Davies RR, Turner SJ, Parkin JM, Johnson DG. The response of normal subjects and patients with idiopathic growth hormone deficiency to continuous infusion of human pancreatic growth hormone releasing factor 1-44. Clin Endocrinol (Oxf) 1984; 21:569-74
7. Borges JLC, Blizzard RM, Evans WS, Furlanetto R, Rogol AD, Kaiser DL, et al. Stimulation of growth hormone (GH) and somatomedin C in idiopathic GH-deficient subjects by intermittent pulsatile administration of synthetic human pancreatic tumor GH-releasing factor. J Clin Endocrinol Metab 1984;59:1-6
8. Hizuka H, Takano K, Shizume K, Tanaka I, Honda N, Ling NC. Plasma growth hormone (GH) and somatomedin C response to continuous growth hormone-releasing factor (GHRF) infusion in patients with GH deficiency. Acta Endocrinol (Copenh) 1985; 110:17-23
9. Takano K, Hizuka N, Shizume K, Asakawa K, Miyakawa M, Hirose N, et al. Plasma growth hormone (GH) response to GH-releasing factor in normal children with short stature and patients with pituitary dwarfism. J Clin Endocrinol Metab 1984;58:236-41
10. Maghnie M, Triulzi F, Larizza D, Scotti G, Beluffi G, Cecchini A, et al. Hypothalamic-pituitary dwarfism: comparison between MR imaging and CT findings. Pediatr Radiol 1990;20:229-35
11. Maghnie M, Triulzi F, Larizza D, Preti P, Prior C, Scotti G, et al. Hypothalamic-pituitary dysfunction in growth hormone-deficient patients with pituitary abnormalities. J Clin Endocrinol Metab 1991;73:79-83
12. Maghnie M, Larizza D, Triulzi F, Sampaolo P, Scotti G, Severi F. Hypopituitarism and stalk agenesis: a congenital syndrome worsened by breech delivery? Horm Res 1991;35:104-8
13. Cohen L, Wondisford FE, Salvatoni A, Maghnie M, Brucker-Davis F, Weintraub BD, et al. A hot spot in the Pit-1 gene responsible for combined pituitary hormone deficiency: clinical and molecular correlates. J Clin Endocrinol Metab 80:579-84
14. Gelato MC, Malozowski S, Caruso-Nicoletti M, Levine Ross J, Pescovitz OH, Rose S, et al. Growth hormone (GH) responses to GH-releasing hormone during pubertal development in normal boys and girls: comparison to idiopathic short stature and GH deficiency. J Clin Endocrinol Metab 1986;63:174-9
15. Duck SC, Schwarz HP, Costin G, Rapaport R, Arslanian S, Hayek A, et al. Subcutaneous growth hormone-releasing hormone therapy in growth-deficient children: first year of therapy. J Clin Endocrinol Metab 1992;75:1115-20
16. Maghnie M, Marconi M, Toniolo D, Bartolini P, Larizza D, Preti P, et al. Growth hormone releasing hormone gene analysis by phGRF54 probe in hypopituitarism [abstract]. Horm Res 1992;37 Suppl 4:S201
17. Maghnie M, Lorini R, Vitali L, Mastricci N, Carrà AM, Severi F. Organ-and non-organ-specific auto-antibody in children with hypopituitarism on growth hormone therapy. Eur J Pediatr 1995;154:450-3
18. Maghnie M, Larizza D, Zuliani I, Severi F. Congenital central nervous system abnormalities, idiopathic hypopituitarism and breech delivery: what is the connection? [letter], Eur J Pediatr 1993;152:175-6
19. Di Chiro G, Nelson KB. Volume of the sella turcica. Am J Radiol 1962;87:989-1008
20. Loche S, Cambiaso P, Merola B, Colao A, Faedda A, Imbimbo BP, et al. The effect of hexarelin on growth hormone (GH) secretion in patients with GH deficiency. J Clin Endocrinol Metab 1995;80: 2692-6
21. Pombo M, Barreiro J, Penalva A, Peino R, Dieguez C, Casanueva FF. Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH). GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary transection. J Clin Endocrinol Metab 1995;80:3180-4
22. Van Hauthem H. Toppet V, Van Vliet G. Congenital hypopituitarism: results of pituitary stimulation tests and of magnetic resonance imaging in a newborn girl. Eur J Pediatr 1992;151: 174-6
23. Toogood AA, Beardwell CG, Shalet SM. The severity of growth hormone deficiency in adults with pituitary disease is related to the degree of hypopituitarism. Clin Endocrinol (Oxf) 1994;41: 511-6
24. Cella SG, Locatelli V, Mennini T, Zanini A, Bendotti C, Forloni GL, et al. Deprivation of growth hormone-releasing hormone early in the rat's neonatal life permanently affects somatotropic function. Endocrinology 1990;127:1625-34
25. Cella SG, De Gennaro Colonna V, Locatelli V, Bestetti GE, Rossi GL, Torsello A, et al. Somatotropic dysfunction in growth hormone-releasing hormone-deprived neonatal rats: effect of growth hormone replacement therapy. Pediatr Res 1994;36: 315-22
26. Rimoin DL, Schecther JE. Histological and ultrastructural studies in isolated growth hormone deficiency. J Clin Endocrinol Metab 1973;37:725-35
27. Maghnie M, Valtorta A, Moretta A, Larizza D, Preti P, Palladini G, et al. Diagnosing growth hormone hormone deficiency: the value of short term hypocaloric diet. J Clin Endocrinol Metab 1993;77:1372-8
28. Rosenthal SM, Kaplan SL, Grumbach MM. Short term continuous intravenous infusion of growth hormone (GH) inhibits GH-releasing hormone-induced GH secretion: a time-dependent effect. J Clin Endocrinol Metab 1989;68:1101-5
29. Wu RHK, Youlaine STL, Di Martino-Nardi J, Wesoly S, Sobel EH, Sherman B, et al. Preservation of physiological growth hormone (GH) secretion in idiopathic short stature after recombinant GH therapy. J Clin Endocrinol Metab 1990;70:1612-5
30. Abrams RL, Grumbach MM, Kaplan SL. The effect of administration of human growth hormone on the plasma growth hormone, cortisol, glucose, and free fatty acid response to insulin: evidence for growth hormone autoregulation in man. J Clin Invest 1971;50:940-50
31. Devesa J, Lima L, Lois N, Lechjga MJ, Arche V. Tresguerres JAF. Reasons for the variability in growth hormone (GH) responses to GHRH challenge: the endogenous hypothalamic-somatotroph rythm (HSR). Clin Endocrinol (Oxf) 1989;30: 367-77
32. Suri D, Hindmarsh PC, Brain CE, Pringle PJ, Brook CGD. The interaction between clonidine and growth hormone releasing hormone in the stimulation of growth hormone seecretion in man. Clin Endocrinol (Oxf) 1990;33:399-406
33. Tannenbaum GS, Ling N. The interrelationship of growth hormone-releasing factor and somatostatin in generation of the ultradian rhythm of growth hormone secretion. Endocrinology 1984;115:1952-7
34. Copeland KC, Underwood LE, Van Wyk JJ. Induction of immunoreactive somatomedin C in human serum by growth of hormone: dose-response relationships and effect on chromatographic profiles. J Clin Endocrinol Metab 1980;50: 690-7