The pulmonary uptake of intravenously administered liposomal α-tocopherol is augmented in acute lung injury

Journal of Drug Targeting

Volumn 4, Issue 3, 1996, Pages 151-159

  Suntres, Z E ^a   Shek, P N ^a,b  

^a DEF AND CIV INST OF ENVIRON MED   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Antioxidant; Drug delivery; Liposome; Lung injury; tocopherol

Indexed keywords

ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; ANTIOXIDANT; DIPALMITOYLPHOSPHATIDYLCHOLINE; DIPEPTIDYL PEPTIDASE; LIPOSOME; PARAQUAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIUM; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG TISSUE LEVEL; DRUG UPTAKE; ENZYME ACTIVITY; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0029837618     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611869609015972     Document Type: Article

References (37)

1. Bakker-Woudenberg, I.A.J.M., Lokerse, A.F., Ten Kate, M.T., Storm, G. (1992) Enhanced localization of liposomes with prolonged blood circulation time in infected lung tissue. Biochim Biophys Acta 1138, 318-326.
2. Bernard, G.R., Luce, J.M., Sprung, C.L., Rinaldo, J.E., Tate, R.M., Sibbald, W.J., Kariman, K., Higgins, S., Bradley, R , Metz, C.A., Harris, T.R., Brigham, K.L. (1987) High-dose corticosteroids in patients with adult respiratory distress syndrome. N Eng J Med 317, 1565-1570.
3. Blennerhassett, J.B. (1985) Shock lung and diffuse alveolar damage: Pathological and pathogenetic considerations. Pathology 17, 239-247.
4. Boobis, A.R., Fawthrop, D.J., Davis, D.S. (1989) Mechanisms of cell death. Trends Pharmacol Sci 10, 275-280.
5. Boudreau, J., Nadeau, D (1987) Lung hydrolases in paraquat poisoning: early response of alkaline phosphatase. J Toxicol Environm Health 22, 329-340.
6. Bucher, J.R., Roberts, R. (1981) α-Tocopherol (vitamin E) content of lung, liver and blood in the newborn rat and human infant: influence of hyperoxia. J Pediat 98, 806-811.
7. Byrne, K., Carey, P.D., Sugerman, H.J. (1987) Adult respiratory distress syndrome. Acute Care 13, 206-234.
8. Cross, C.E., van der Vliet, A., O'Neill, C.A., Eiserich, J.P. (1994) Reactive oxygen species and the lung. Lancet 344, 930-933.
9. Gad, S.C., Weil, C.S. (1994) Statistics for Toxicologists. In Principles and Methods of Toxicology, A.W. Hayes (ed), Raven Press, New York, pp 221-274.
10. Heath, D., Smith, P. (1977) The pathology of the lung in paraquat poisoning. In Biochemical Mechanisms of Paraquat Toxicity, A.P. Autor (ed), Academic Press, New York, pp 39-51.
11. Hybertson, B.M., Leff, J.A., Repine, J.E. (1993) Pretreatment with inhaled vitamin E aerosol rapidly increases vitamin E levels and decreases interleukin-1-induced acute oxidative lung leak in rats. Free Rad Biol 15, 549 (A 12:4).
12. Hwang, K.J. (1987) Liposome pharmacokinetics. In: Liposomes: From Biophysics to Therapeutics, M.J. Ostro (ed), Marcel Dekker, Inc., New York, pp 109-156.
13. Janssen, Y.M.W., van Houten, B., Borm, P.J.A., Mossman, B.T. (1993) Cell and tissue responses to oxidative damage. Lab Invest 69, 261-274.
14. Kehrer, J.P., Kacew, S. (1985) Systematically applied chemicals that damage lung tissue. Toxicol 35, 251-293.
15. Lazo, J.S., Lynch, T.J., McCallister, J. (1986) Bleomycin inhibition of angiotensin converting enzyme activity from serum, lungs and cultured pulmonary artery endothelial cells. Am Rev Respir Dis 134, 73-78.
16. Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193, 265-275.
17. McLean, J.S., Byrick, R.J. (1993) ARDS and sepsis-definitions and new therapy. Can J Anaesth 40, 585-590.
18. Muller, M.J., Herndon, D.N. (1994) The challenge of burns. Lancet 343, 216-219.
19. Mulligan, M.S., Varani, J., Dame, M.K., Lane, C.L., Smith, C.W., Anderson, D.C., Ward, P.A. (1991) Role of endothelial-leukocyte adhesion molecule-1 (ELAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest 88, 1396-1406.
20. Nakagawa, Y., Nojima, S., Inoue K. (1980) Transfer of steroids and α-tocopherol between liposomal membranes. J. Biochem. 87, 497-502.
21. Omri, A., Beaulac, C., Bouhajib, M., Montplaisir, S., Sharkawi, M., Lagace, J. (1994) Pulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with Pseudomonas aeruginosa. Antimicrob Agents Chemother 38, 1090-1095.
22. Padmanabhan, R.V., Gudapaty, R., Liener, I.E., Schwartz, B.A., Hoidal, J.R. (1985) Protection against pulmonary oxygen toxicity in rats by the intratracheal administration of liposome-encapsulated superoxide dismutase or catalase. Am Rev Respir Dis 32, 164-167.
23. Panus, P.C., Freeman, B.A. (1988) Liposome-entrapped superoxide dismutase: in vitro and in vivo effects. In Liposomes as Drug Carriers, G. Gregoriadis (ed), John Willey, Chichester, pp. 473-482.
24. Pasi, A. (1978) The toxicity of Paraquat, Diquat and Morfamquat. Hans Huber Publishers, Bern.
25. Poste, G., Kirsh, R., Koestler, T. (1984) The challenge of liposome targeting in vivo. In CRC Liposome Technology. Volume III: Targeted Drug Delivery and Biological Interaction. G. Gregoriadis (ed), CRC Press, Inc., Boca Raton, pp. 1-28.
26. 1 does not alter mortality of adult respiratory distress syndrome. Chest 92, 59S.
27. Schiller, H.J., Reilly, P.M., Bulkley, G.B. (1993) Antioxidant therapy. Crit Care Med 21, S92-S103.
28. Senior, J.H. (1987) Fate and behavior of liposomes in vivo: a review of controlling factors. Crit Rev Ther Drug Carrier Systems 3, 123-193.
29. Shek, P.N., Suntres, Z.E., Brooks, J.I. (1994) Liposomes in pulmonary applications: Physicochemical considerations, pulmonary distribution and antioxidant delivery. J Drug Targeting 2, 431-442.
30. Smith, L.J., Anderson, J. (1993) Lung retention of phosphatidylcholine and cholesterol from liposomes: effects of oxygen exposure and fasting. J Appl Physiol 74, 1899-1904.
31. Suntres, Z.E., Hepworth, S.R., Shek, P.N. (1992) Protective effect of liposome-associated α-tocopherol against paraquat-induced acute lung toxicity. Biochem Pharmacol 44, 1811-1818.
32. Suntres, Z.E., Shek, P.N. (1995) Liposome-associated antioxidants for pulmonary applications. In Liposomes in Biomedical Application, P.N. Shek (ed), Harwood Academic Publishers, Amsterdam, pp. 179-198.
33. Turrens, J.F., Crapo, J.D., Freeman, B.A. (1984) Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase. J Clin Inv 73, 87-95.
34. Villar, J., Slutsky, A.S. (1989) The incidence of the adult respiratory distress syndrome. Am Rev Respir Dis 140, 814-816.
35. Ward, H.E., Hicks, M., Nicholson, A., Berend, N. (1988) Deferoxamine infusion does not inhibit bleomycin-induced lung damage in the rat. Am Rev Respir Dis 137, 1356-1359.
36. Weinberger, S.E. (1993) Recent advances in pulmonary medicine. N Engl J Med 328, 1462-1470.
37. Wispe, J.R., Knight, M., Roberts, R.J. (1986) Lipid peroxidation in newborn rabbits: effects of oxygen, lipid emulsion, and vitamin E. Pediatric Res 20, 505-510.