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Volumn 88, Issue 6, 1996, Pages 2219-2227

Interleukin-6 promotes multiple myeloma cell growth via phosphorylation of retinoblastoma protein

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CD40 ANTIGEN; ELONGATION FACTOR 2; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; MONOCLONAL ANTIBODY; RETINOBLASTOMA PROTEIN;

EID: 0029837401     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.6.2219.bloodjournal8862219     Document Type: Article
Times cited : (85)

References (59)
  • 1
    • 0024360388 scopus 로고
    • The biology of interleukin-6
    • Kishimoto T: The biology of interleukin-6. Blood 74:1, 1989
    • (1989) Blood , vol.74 , pp. 1
    • Kishimoto, T.1
  • 2
    • 0019495308 scopus 로고
    • T cell-replacing factor (TFR)-induced IgG secretion in human B blastoid cell line and demonstration of acceptors for TRF
    • Muraguchi A, Kishimoto T, Miki Y, Kuritani T, Kaieda T, Yoshizaki K, Yamamura Y: T cell-replacing factor (TFR)-induced IgG secretion in human B blastoid cell line and demonstration of acceptors for TRF. J Immunol 127:412, 1981
    • (1981) J Immunol , vol.127 , pp. 412
    • Muraguchi, A.1    Kishimoto, T.2    Miki, Y.3    Kuritani, T.4    Kaieda, T.5    Yoshizaki, K.6    Yamamura, Y.7
  • 5
    • 0024391288 scopus 로고
    • Response of purified myeloma cells to hematopoietic growth factors
    • Anderson KC, Jones RC, Morimoto C, Leavitt P, Barut B: Response of purified myeloma cells to hematopoietic growth factors. Blood 73:1915, 1989
    • (1989) Blood , vol.73 , pp. 1915
    • Anderson, K.C.1    Jones, R.C.2    Morimoto, C.3    Leavitt, P.4    Barut, B.5
  • 6
    • 0027302498 scopus 로고
    • Interleukin-6 gene expression in multiple myeloma: A characteristic of immature tumor cells
    • Hata H, Xiao H, Petrucci MT, Woodliff J, Chang R, Epstein J: Interleukin-6 gene expression in multiple myeloma: A characteristic of immature tumor cells. Blood 81:3357, 1993
    • (1993) Blood , vol.81 , pp. 3357
    • Hata, H.1    Xiao, H.2    Petrucci, M.T.3    Woodliff, J.4    Chang, R.5    Epstein, J.6
  • 8
    • 0026005560 scopus 로고
    • Role of interleukin-6 in the proliferation of human multiple myeloma cell lines OCI-MY1-7 established from patients with advanced stage of the disease
    • Hitzler J, Martinez-Valdez H, Bergsagel D, Minden MD: Role of interleukin-6 in the proliferation of human multiple myeloma cell lines OCI-MY1-7 established from patients with advanced stage of the disease. Blood 78:1996, 1991
    • (1991) Blood , vol.78 , pp. 1996
    • Hitzler, J.1    Martinez-Valdez, H.2    Bergsagel, D.3    Minden, M.D.4
  • 9
    • 0028172986 scopus 로고
    • Disruption by interferon-α of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterogenous down-regulation of IL-6 receptor α- and β-chains
    • Schwab M, Brini AT, Bosco MC, Rubboli F, Egawa M, Zhao J, Princler GL, Kung H: Disruption by interferon-α of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterogenous down-regulation of IL-6 receptor α- and β-chains. J Clin Invest 94:2317, 1994
    • (1994) J Clin Invest , vol.94 , pp. 2317
    • Schwab, M.1    Brini, A.T.2    Bosco, M.C.3    Rubboli, F.4    Egawa, M.5    Zhao, J.6    Princler, G.L.7    Kung, H.8
  • 10
    • 0025737915 scopus 로고
    • Interleukin-6 antisense oligonucleotides inhibit the growth of human myeloma cell lines
    • Levy Y, Tsapis A, Brouet JC: Interleukin-6 antisense oligonucleotides inhibit the growth of human myeloma cell lines. J Clin Invest 88:696, 1991
    • (1991) J Clin Invest , vol.88 , pp. 696
    • Levy, Y.1    Tsapis, A.2    Brouet, J.C.3
  • 12
    • 0024419152 scopus 로고
    • Production of cytokines by bone marrow cells obtained from patients with multiple myeloma
    • Lichtenstein A, Berenson J, Norman D, Chang MP, Carlile A: Production of cytokines by bone marrow cells obtained from patients with multiple myeloma. Blood 74:1266, 1989
    • (1989) Blood , vol.74 , pp. 1266
    • Lichtenstein, A.1    Berenson, J.2    Norman, D.3    Chang, M.P.4    Carlile, A.5
  • 15
    • 0027133422 scopus 로고
    • Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion
    • Uchiyama H, Barut BA, Mohrbacher AF, Chauhan D, Anderson KC: Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. Blood 82:3712, 1993
    • (1993) Blood , vol.82 , pp. 3712
    • Uchiyama, H.1    Barut, B.A.2    Mohrbacher, A.F.3    Chauhan, D.4    Anderson, K.C.5
  • 16
    • 0026661556 scopus 로고
    • Lymphocyte function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma
    • Ahsmann EJM, Lokhorst HM, Dekker AW, Bloem AC: Lymphocyte function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma. Blood 79:2068, 1992
    • (1992) Blood , vol.79 , pp. 2068
    • Ahsmann, E.J.M.1    Lokhorst, H.M.2    Dekker, A.W.3    Bloem, A.C.4
  • 18
    • 0028928641 scopus 로고
    • Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis
    • Kawano MM, Mihara K, Huang N, Tsujimoto T, Kuramoto A: Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis. Blood 85:487, 1995
    • (1995) Blood , vol.85 , pp. 487
    • Kawano, M.M.1    Mihara, K.2    Huang, N.3    Tsujimoto, T.4    Kuramoto, A.5
  • 20
    • 0024832002 scopus 로고
    • Serum levels of interleukin-6, a potent myeloma cell growth factor, as a reflect of disease severity of plasma cell dyscrasias
    • Bataille R, Jourdan M, Zhang X-G, Klein B: Serum levels of interleukin-6, a potent myeloma cell growth factor, as a reflect of disease severity of plasma cell dyscrasias. J Clin Invest 84:2008, 1989
    • (1989) J Clin Invest , vol.84 , pp. 2008
    • Bataille, R.1    Jourdan, M.2    Zhang, X.-G.3    Klein, B.4
  • 22
    • 0028267592 scopus 로고
    • High levels of interleukin-6 are associated with low tumor burden and low growth fraction in multiple myeloma
    • Ballester OF, Moscinski, LC, Lyman GH, Chancy JV, Saba HI, Spiers ASD, Klein B: High levels of interleukin-6 are associated with low tumor burden and low growth fraction in multiple myeloma. Blood 83: 1903, 1994
    • (1994) Blood , vol.83 , pp. 1903
    • Ballester, O.F.1    Moscinski, L.C.2    Lyman, G.H.3    Chancy, J.V.4    Saba, H.I.5    Spiers, A.S.D.6    Klein, B.7
  • 25
    • 0029069307 scopus 로고
    • Interleukin 6 is essential for in vivo development of B lineage neoplasms
    • Hubert DM, Kopf M, Mock BA, Kohler G, Rudikoff S: Interleukin 6 is essential for in vivo development of B lineage neoplasms. J Exp Med 182: 243, 1995
    • (1995) J Exp Med , vol.182 , pp. 243
    • Hubert, D.M.1    Kopf, M.2    Mock, B.A.3    Kohler, G.4    Rudikoff, S.5
  • 29
    • 0025810049 scopus 로고
    • G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment
    • Mittnacht S, Weinberg RA: G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment. Cell 65: 381, 1991
    • (1991) Cell , vol.65 , pp. 381
    • Mittnacht, S.1    Weinberg, R.A.2
  • 30
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA: The retinoblastoma protein and cell cycle control. Cell 81: 323, 1995
    • (1995) Cell , vol.81 , pp. 323
    • Weinberg, R.A.1
  • 32
    • 0028267869 scopus 로고
    • DRTF1/E2F: An expanding family of heterodimeric transcription factors implicated in cell-cycle control
    • LaThangue NB; DRTF1/E2F: An expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem Sci 19:108, 1994
    • (1994) Trends Biochem Sci , vol.19 , pp. 108
    • LaThangue, N.B.1
  • 37
    • 0023243773 scopus 로고
    • Establishment and phenotypic characterization of three new human myeloma cell lines (U-1957, U-1958, and U-1996)
    • Jernberg H, Nilsson K, Zech L, Lutz D, Nowotny H, Scheirer W: Establishment and phenotypic characterization of three new human myeloma cell lines (U-1957, U-1958, and U-1996). Blood 69:1605, 1987
    • (1987) Blood , vol.69 , pp. 1605
    • Jernberg, H.1    Nilsson, K.2    Zech, L.3    Lutz, D.4    Nowotny, H.5    Scheirer, W.6
  • 38
  • 39
    • 0024364791 scopus 로고
    • Establishment of a human leukaemic cell line (CMK) with megakaryocytic characteristics from a Down's syndrome patient with acute megakaryocytic leukemia
    • Sato T, Fuse A, Eguchi M, Hayashi Y, Ryo R, Adachi M, Kishimoto Y, Teramura M, Mizoguchi H, Shima Y: Establishment of a human leukaemic cell line (CMK) with megakaryocytic characteristics from a Down's syndrome patient with acute megakaryocytic leukemia. Br J Haematol 72:184, 1989
    • (1989) Br J Haematol , vol.72 , pp. 184
    • Sato, T.1    Fuse, A.2    Eguchi, M.3    Hayashi, Y.4    Ryo, R.5    Adachi, M.6    Kishimoto, Y.7    Teramura, M.8    Mizoguchi, H.9    Shima, Y.10
  • 40
    • 0026090394 scopus 로고
    • Interleukin 6, a possible autocrine growth and differentiation factor for the human megakaryocytic cell line, CMK
    • Fuse A, Kakuda T, Shima Y, Van Damme J, Billiau A, Sato T: Interleukin 6, a possible autocrine growth and differentiation factor for the human megakaryocytic cell line, CMK. Br J Haematol 77:32, 1991
    • (1991) Br J Haematol , vol.77 , pp. 32
    • Fuse, A.1    Kakuda, T.2    Shima, Y.3    Van Damme, J.4    Billiau, A.5    Sato, T.6
  • 41
    • 0028795345 scopus 로고
    • Growth enhancement of normal human keratinocytes by the antisense oligonucleotide of retinoblastoma susceptibility gene
    • Koike M, Ishino K, Ikuta T, Huh N, Kuroki T: Growth enhancement of normal human keratinocytes by the antisense oligonucleotide of retinoblastoma susceptibility gene. Oncogene 10:117, 1995
    • (1995) Oncogene , vol.10 , pp. 117
    • Koike, M.1    Ishino, K.2    Ikuta, T.3    Huh, N.4    Kuroki, T.5
  • 42
  • 46
    • 0028880424 scopus 로고
    • Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities
    • Tricot G, Barlogie B, Jagannath S, Bracy D, Mattox S, Vesole DH, Naucke S, Sawyer JR: Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities. Blood 86:4250, 1995
    • (1995) Blood , vol.86 , pp. 4250
    • Tricot, G.1    Barlogie, B.2    Jagannath, S.3    Bracy, D.4    Mattox, S.5    Vesole, D.H.6    Naucke, S.7    Sawyer, J.R.8
  • 48
    • 0029134016 scopus 로고
    • Role of the cyclin-dependent kinase inhibitors in the development of cancer
    • Hirama T, Koeffler PH: Role of the cyclin-dependent kinase inhibitors in the development of cancer. Blood 86:841, 1995
    • (1995) Blood , vol.86 , pp. 841
    • Hirama, T.1    Koeffler, P.H.2
  • 51
    • 0025775929 scopus 로고
    • Repression of interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product
    • Santhanam U, Ray A, Sehgal P: Repression of interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product. Proc Natl Acad USA 88:7605, 1991
    • (1991) Proc Natl Acad USA , vol.88 , pp. 7605
    • Santhanam, U.1    Ray, A.2    Sehgal, P.3
  • 52
    • 0025168432 scopus 로고
    • Negative regulation of human c-fos expression by the retinoblastoma gene product
    • Robbins PD, Horowitz JM, Mulligan RC: Negative regulation of human c-fos expression by the retinoblastoma gene product. Nature 346:668, 1990
    • (1990) Nature , vol.346 , pp. 668
    • Robbins, P.D.1    Horowitz, J.M.2    Mulligan, R.C.3
  • 53
    • 0025047444 scopus 로고
    • On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: Enhancer, TATA box, and RNA start site (Inf Motif) occlusion
    • Ray A, LaForge K, Sehgal PB: On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (Inf Motif) occlusion. Mol Cell Biol 10:5736, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 5736
    • Ray, A.1    LaForge, K.2    Sehgal, P.B.3
  • 54
    • 0028942949 scopus 로고
    • The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter
    • Adnanet J, Shao ZZ, Robbins PD: The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter. J Biol Chem 270:8837, 1995
    • (1995) J Biol Chem , vol.270 , pp. 8837
    • Adnanet, J.1    Shao, Z.Z.2    Robbins, P.D.3
  • 57
    • 0028365819 scopus 로고
    • Decreased retinoblastoma protein expression in acute myeloblastic leukemia is associated with the autologous proliferation of clonogenic blasts
    • Zhu Y-M, Bradbury D, Russell N: Decreased retinoblastoma protein expression in acute myeloblastic leukemia is associated with the autologous proliferation of clonogenic blasts. Br J Haematol 86:533, 1994
    • (1994) Br J Haematol , vol.86 , pp. 533
    • Zhu, Y.-M.1    Bradbury, D.2    Russell, N.3
  • 58
    • 0028125327 scopus 로고
    • Absence of retinoblastoma protein expression results in autocrine production of interleukin-6 and promotes the autonomous growth of acute myeloid leukemia blast cells
    • Zhu Y-M, Bradbury DA, Keith FJ, Russell N: Absence of retinoblastoma protein expression results in autocrine production of interleukin-6 and promotes the autonomous growth of acute myeloid leukemia blast cells. Leukemia 8:1982, 1994
    • (1994) Leukemia , vol.8 , pp. 1982
    • Zhu, Y.-M.1    Bradbury, D.A.2    Keith, F.J.3    Russell, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.