Cloning and identification of HEM14, the yeast gene for mitochondrial protoporphyrinogen oxidase

Yeast

Volumn 12, Issue 14, 1996, Pages 1421-1425

  Glerum, D Moira ^a   Shtanko, Andrey ^a   Tzagoloff, Alexander ^a   Gorman, Nadia ^b   Sinclair, Peter R ^b  

^a Columbia University ^*  (United States)

^b VA MEDICAL CENTER   (United States)

Author keywords

chromosome V; functional analysis; HEM14; protoporphyrinogen oxidase; Saccharomyces cerevisiae; YER014

Indexed keywords

PROTOPORPHYRINOGEN OXIDASE;

ARTICLE; CHROMOSOME 5; CONTROLLED STUDY; DNA SEQUENCE; GENETIC ANALYSIS; MOLECULAR CLONING; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

CLONING, MOLECULAR; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; HEME; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; OXYGEN CONSUMPTION; PHENOTYPE; PORPHYRINS; PROTOPORPHYRINOGEN OXIDASE; RESTRICTION MAPPING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY; SPECIES SPECIFICITY;

SACCHAROMYCES CEREVISIAE;

EID: 0029836923     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0061(199611)12:14<1421::AID-YEA38>3.0.CO;2-W     Document Type: Article

References (22)

1. Amillet, J. M. and Labbe-Bois, R. (1995). Isolation of the gene HEM4 encoding uroporphyrinogen III synthase in Saccharomyces cerevisiae. Yeast 11, 419-424.
2. Botstein, D. and Davis, R. W. (1982). Principles and practice of recombinant DNA research with yeast. In Strathern, J. N., Jones, E. W. and Broach, J. R. (Eds), The Molecular Biology of the Yeast Saccharomyces cerevisiae: Metabolism and Gene Expression. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 607-636.
3. Camadro, J. M., Thome, F., Brouillet, N. and Labbe, P. (1994). Purification and properties of protoporphyrinogen oxidase from the yeast Saccharomyces cerevisiae. Mitochondrial location and evidence for a precursor form of the protein. J. Biol. Chem. 269, 32085-32091.
4. Dailey, T, A., Meissner, P. and Dailey, H. A. (1994). Expression of a cloned protoporphyrinogen oxidase. J. Biol. Chem. 269, 813-815.
5. Dietrich, F. S., et al. (1995). Complete sequence Saccharomyces cerevisiae chromosome V. GenBank, Accession No. U18778.
6. Faye, G., Kujawa, C. and Fukuhara, H. (1974). Physical and genetic organization of petite and grande yeast mitochondrial DNA. J. Mol. Biol. 88, 185-203.
7. Feinberg, A. P. and Vogelstein, B. (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6-13.
8. Garey, J. R., Labbe-Bois, R., Chelstowska, A., et al. (1992). Uroporphyrinogen decarboxylase in Saccharomyces cerevisiae. HEM12 gene and evidence for two conserved glycines essential for enzymatic activity. Eur. J. Biochem. 205, 1011-1016.
9. Gollub, E. G., Liu, K. P., Dayan, J., Adlersberg, M. and Sprinson, D. B. (1977). Yeast mutants deficient in heme biosynthesis and a heme mutant additionally blocked in cyclization of 2,3-oxidosqualene. J. Biol. Chem. 252, 2846-2854.
10. Granick, S. and Beale, S. I. (1978). Hemes, chlorophylls, and related compounds: Biosynthesis and metabolic regulation. In Meister, A. (Ed.), Advances in Enzymology and Related Areas of Molecular Biology. Wiley, New York, pp 33-203.
11. Hill, J. E., Myers, A. M., Koerner, T. J. and Tzagoloff, A. (1986). Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast 2, 163-167.
12. Jacobs, J. M., Sinclair, P. R., Gorman, N., et al. (1992). Effects of diphenyl ether herbicides on porphyrin accumulation by cultured hepatocytes. J. Biochem. Toxicol. 7, 87-95.
13. Labbe-Bois, R. (1991). The ferrochelatase from Saccharomyces cerevisiae. Sequence, disruption, and expression of its structural gene. J. Biol. Chem. 265, 7278-7283.
14. Maniatis, T., Fritsch, E. F. and Sambrook, J. (1982). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
15. Maxam, A. M. and Gilbert, W. (1977). A new method for sequencing DNA. Proc. Natl. Acad. Sci. USA 74, 560-565.
16. Myers, A. M., Pape, K. L. and Tzagoloff, A. (1985). Mitochondrial protein synthesis is required for maintenance of intact mitochondrial genomes in Saccharomyces cerevisiae. EMBO J. 4, 2087-2092.
17. Rothstein, R. J. (1983). One-step gene disruption in yeast. Methods Enzymol. 101, 202-211.
18. Schiestl, R. H. and Gietz, R. D. (1989). High efficiency transformation of intact yeast cells using single stranded nucleic acids as carriers. Curr. Genet. 16, 339-346.
19. Sinclair, P. R., Gorman, N., Walton, H. S., Sinclair, J. F., Jacobs, J. M. and Jacobs, N. J. (1994). Protoporphyrinogen accumulation in cultured hepatocytes treated with the diphenyl ether herbicide, acifluorfen. Cell. Mol. Biol. 40, 891-897.
20. Tzagoloff, A. and Dieckmann, C. L. (1990). PET genes of Saccharomyces cerevisiae. Microbiol. Rev. 54, 211-225.
21. Urban-Grimal, D. and Labbe-Bois, R. (1981). Genetic and biochemical characterization of mutations of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis. Molec. Gen. Genet. 183, 85-92.
22. Urban-Grimal, D., Volland, C., Gamier. T., Dehoux, P. and Labbe-Bois, R. (1986). The nucleotide sequence of the HEM1 gene and evidence for a precursor form of the mitochondrial 5-aminolevulinate synthase in Saccharomyces cerevisiae. Eur. J. Biochem. 156, 511-519.