Insulin-stimulated glucose uptake involves the transition of glucose transporters to a caveolae-rich fraction within the plasma membrane: Implications for type II diabetes

Molecular Medicine

Volumn 2, Issue 3, 1996, Pages 367-372

  Gustavsson, Johanna ^a   Parpal, Santiago ^a   Strålfors, Peter ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; DETERGENT; GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; ISOPRENALINE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CONTROLLED STUDY; EPIDIDYMIS FAT; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0029836236     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03401634     Document Type: Article

References (22)

1. Cushman SW, Wardzala LJ. (1980) Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. J. Biol. Chem. 255: 4758-4762.
2. Suzuki K, Kono T. (1980) Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site. Proc. Natl. Acad. Sci. U.S.A. 77: 2542-2545.
3. Karnieli E, Zarnowski M, Hissin PJ, Simpson IA, Salans LB, Cushman SW. (1981) Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. J. Biol. Chem. 256: 4772-4777.
4. Satoh S, Nishimura H, Clark A, et al. (1993) Use of bis-mannitol photolabel to elucidate insulin-regulated GLUT-4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action. J. Biol. Chem. 268: 17820-17829.
5. Gibbs EM, Lienhard GE, Gould GW. (1988) Insulin-induced translocation of glucose transporters to the plasma membrane pre-cedes full stimulation of hexose transport. Biochemistry 27: 6681-6685.
6. Joost HG, Weber TM, Cushman SW. (1988) Qualitative and quantitative comparison of glucose transport activity and glucose transporter concentration in plasma membranes from basal and insulin-stimulated rat adipose cells. Biochem. J. 249: 155-161.
7. Lange K, Brandt U. (1990) Insulin-responsive glucose transporters are concentrated in a cell surface-derived membrane fraction of 3T3-L1 adipocytes. FEBS Lett. 261: 459-463.
8. Clark AE, Holman GD, Kozka IJ. (1991) Determination of the rates of appearance and loss of glucose transporters at the cell surface of rat adipose cells. Biochem. J. 278: 235-241.
9. Smith RM, Charron MJ, Shah N, Lodish HF, Jarett L. (1991) Immunoelectron microscopic demonstration of insulin-stimulated translocation of glucose transporters to the plasma membrane of isolated rat adipocytes and masking of the carboxyl-terminal epitope of intracellular GLUT4. Proc. Natl. Acad. Sci. U.S.A. 88: 6893-6897.
10. Vannucci SJ, Nishimura H, Satoh S, Cushman SW, Holman GD, Simpson IA. (1992) Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells, modulation by isoprenaline and adenosine. Biochem. J. 288: 325-330.
11. Holman GD, Leggio LL, Cushman SW. (1994) Insulin-stimulated GLUT4 glucose transporter recycling. J. Biol. Chem. 269: 17516-17524.
12. Scherer PE, Lisanti MP, Baldini G, Sargiacomo M, Mastick CC, Lodish HF. (1994) Induction of caveolin during adipogenesis and association of GLUT4 with cavolin-rich vesicles. J. Cell Biol. 127: 1233-1243.
13. Kandror KV, Stephens JM, Pilch PF. (1995) Expression and compartmentalisation of caveolin in adipose cells: co-ordinate regulation with and structural segregation from GLUT4. J. Cell Biol. 129: 999-1006.
14. Parpal S, Gustavsson J, Strålfors P. (1995) Isolation of phosphooligosaccharide/phosphoinositol glycan from caveolae and from cytosol of insulin-stimulated cells. J. Cell Biol. 131: 125-135.
15. Strålfors P, Honnor RC. (1989) Insulin-induced dephosphorylation of hormone-sensitive lipase, correlation with lipolysis and cAMP-dependent protein kinase activity. Eur. J. Biochem. 182: 379-385.
16. Strålfors P. (1988) Insulin stimulation of glucose uptake can be mediated by diacylglycerol in adipocytes. Nature (Lond.) 335: 554-556.
17. Oka Y, Czech M. (1984) Photoaffinity labelling of insulin-sensitive hexose transporters in intact rat adipocytes, direct evidence that latent transporters become exposed to the extracellular space in response to insulin. J. Biol. Chem. 259: 8125-8133.
18. McKeel DW, Jarett L. (1970) Preparation and characterisation of a plasma membrane fraction from isolated fat cells. J. Cell Biol. 44: 417-432.
19. Chang WJ, Ying YS, Rothberg KG, et al. (1994) Purification and characterisation of smooth muscle cell caveolae. J. Cell Biol. 126: 127-138.
20. Sargiacomo M, Sudol M, Tang ZL, Lisanti MP. (1993) Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells. J. Cell Biol. 122: 789-807.
21. Parton GP, Simons K. (1995) Digging into caveolae. Science 269: 1398-1399.
22. Smart EJ, Ying YS, Mineo C, Anderson RGW. (1995) A detergent-free method for purifying caveolae membrane from tissue culture cells. Proc. Natl. Acad. Sci. U.S.A. 92: 10104-10108.