Parenteral iron increases serum erythropoietin concentration during the 'early anaemia' of 10-20-day-old mice

British Journal of Haematology

Volumn 94, Issue 3, 1996, Pages 529-532

  Bechensteen, Anne Grete ^a,b   Halvorsen, Sverre ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

anaemia; Erythropoietin; Iron; Mice; Neonatal

Indexed keywords

ERYTHROPOIETIN; IRON SORBITEX;

AGE; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; FEMALE; IRON DEFICIENCY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029835103     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1818.x     Document Type: Article

References (21)

1. Bechensteen, A.G. & Halvorsen, S. (1994) Serum immunoreactive erythropoietin (siEpo) during the early anaemia in mice: effects of parenteral iron. (Abstract). Clinical Investigation, 72, B12.
2. Bechensteen, A.G., Halvorsen, S. & Skottner, A. (1994) Recombinant human insulin-like growth factor 1 (rh-IGF-1) stimulates erythropoiesis in adult but not in new-born mice. Acta Physiologica Scandinavica, 151, 117-123.
3. Birgegard, G., Wide, L. & Simonsson, B. (1989) Marked erythropoietin increase before fall in Hb after treatment with cytostatic drugs suggests mechanism other than anaemia for stimulation. British Journal of Haematology, 72, 462-466.
4. Bjarnason, I., Cotes, P.M., Knowles, S., Reid, C., Wilkins, R. & Peter, T. (1984) Giant lymph node hyperplasia (Castleman's disease) of the mesentery: observations on the associated anaemia. Gasteroenterology, 87, 216-223.
5. Bozzini, C.E., Alippi, R.M., Barcelo, A.C. & Carro, J. (1989) Correlation between erythropoietic activity and body growth rate in hypertransfused polycythemic growing rats as the result of an erythropoietin-dependent operating mechanism. Experimental Hematology, 17, 77-80.
6. Cazzola, M. & Beguin, Y. (1992) New tools for clinical evaluation of erythron function in man. British Journal of Haematology, 80, 278-284.
7. Deacon, R., Hellebostad, M., Gaines Das, R.E., Milne, A., Rowley, M. & Cotes, P.M. (1993) Invalidity from nonparallelism in a radioimmunoassay for erythropoietin accounted for by human serum antibodies to rabbit lgG. Experimental Hematology, 21, 1680-1685.
8. Goldberg, M.A., Dunning, S.P. & Bunn, H.F. (1988) Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. Science, 242, 1412-1415.
9. Halvorsen, K. & Halvorsen, S. (1973) The 'early anaemia': its relation to postnatal growth rate, milk feeding, and iron availability: experimental study in rabbits. Archives of Diseases in Childhood, 48, 842-849.
10. Halvorsen, K. & Halvorsen, S. (1974) The regulation of erythropoiesis in the suckling rabbit. Pediatric Research, 8, 176-183.
11. Hamilton, D.L. & Cotes, P.M. (1993) The effect of bilateral removal of the submandibular salivary glands on the erythropoietic response of mice. Experimental Hematology, 21, 656-659.
12. Harrison, J., Kappas, A., Levere, R.D., Lutton, J.D., Chertkov, J.L., Jiang, S. & Abraham, N.G. (1993) Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment. Blood, 82, 3574-3579.
13. Holter, P.H., Sanengen, T., Halvorsen, S. & Refsum, H.E. (1987) Regulation of erythropoiesis in suckling rabbits with and without postnatal anemia: partial suppression of production release of erythropoiesis stimulating factor(s) by iron supplements. Pediatric Research, 21, 1-4.
14. Lacombe, C., Dusanter, I., Gobert, S., Muller, O., Gisselbrecht, S. & Mayeux, P. (1994) Intracellular pathways activated by erythropoietin. Annals of the New York Academy of Sciences, 718, 223-230.
15. Porter, D.I., & Goldberg, M.A. (1994) Physiology of erythropoietin production. Seminars in Hematology, 31, 112-121.
16. Sanengen, T., Clemons, G.K., Halvorsen, S. & Widness, J.A. (1989) Immunoreactive erythropoietin and erythropoiesis stimulating factor(s) in plasma from hypertransfused neonatal and adult mice: studies with a radioimmunoassay and a cell culture assay for erythropoietin. Acta Physiologica Scandinavica, 135, 11-16.
17. Sanengen, T. & Halvorsen, S. (1985) Regulation of erythropoiesis during rapid growth. British Journal of Haematology, 61, 273-279.
18. Sjastad, O.V., Framstad, T. & Blom, A.K. (1996) Iron has a direct stimulatory effect on erythropoietin production in anaemic piglets. Acta Veterinaria Scandinavica, 37, in press.
19. Talbot, R.B. & Swenson, M.J. (1970) Blood volume of pigs from birth through 6 weeks of age. American Journal of Physiology, 218, 1141-1144.
20. Wang, G.L. & Semenza, G.L. (1993) Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood, 82, 3610-3615.
21. Widness, J.A., Sanengen, T., Haga, P., Clemons, G.K., Myhre, K. & Halvorsen, S. (1989) Correlation of plasma erythropoiesis stimulating factors and immunoreactive erythropoietin levels during rapid growth in the mouse. Acta Physiologica Scandinavica, 136, 527-533.